KEGG   Hyaena hyaena (striped hyena): 120221741
Entry
120221741         CDS       T07257                                 
Symbol
TGFB2
Name
(RefSeq) transforming growth factor beta-2 proprotein isoform X1
  KO
K13376  transforming growth factor beta-2
Organism
hhv  Hyaena hyaena (striped hyena)
Pathway
hhv04010  MAPK signaling pathway
hhv04060  Cytokine-cytokine receptor interaction
hhv04068  FoxO signaling pathway
hhv04110  Cell cycle
hhv04218  Cellular senescence
hhv04350  TGF-beta signaling pathway
hhv04380  Osteoclast differentiation
hhv04390  Hippo signaling pathway
hhv04933  AGE-RAGE signaling pathway in diabetic complications
hhv05140  Leishmaniasis
hhv05142  Chagas disease
hhv05144  Malaria
hhv05145  Toxoplasmosis
hhv05146  Amoebiasis
hhv05152  Tuberculosis
hhv05161  Hepatitis B
hhv05166  Human T-cell leukemia virus 1 infection
hhv05200  Pathways in cancer
hhv05205  Proteoglycans in cancer
hhv05206  MicroRNAs in cancer
hhv05210  Colorectal cancer
hhv05211  Renal cell carcinoma
hhv05212  Pancreatic cancer
hhv05220  Chronic myeloid leukemia
hhv05225  Hepatocellular carcinoma
hhv05226  Gastric cancer
hhv05321  Inflammatory bowel disease
hhv05323  Rheumatoid arthritis
hhv05410  Hypertrophic cardiomyopathy
hhv05414  Dilated cardiomyopathy
hhv05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:hhv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120221741 (TGFB2)
   04350 TGF-beta signaling pathway
    120221741 (TGFB2)
   04390 Hippo signaling pathway
    120221741 (TGFB2)
   04068 FoxO signaling pathway
    120221741 (TGFB2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    120221741 (TGFB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    120221741 (TGFB2)
   04218 Cellular senescence
    120221741 (TGFB2)
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    120221741 (TGFB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    120221741 (TGFB2)
   05206 MicroRNAs in cancer
    120221741 (TGFB2)
   05205 Proteoglycans in cancer
    120221741 (TGFB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    120221741 (TGFB2)
   05212 Pancreatic cancer
    120221741 (TGFB2)
   05225 Hepatocellular carcinoma
    120221741 (TGFB2)
   05226 Gastric cancer
    120221741 (TGFB2)
   05220 Chronic myeloid leukemia
    120221741 (TGFB2)
   05211 Renal cell carcinoma
    120221741 (TGFB2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    120221741 (TGFB2)
   05161 Hepatitis B
    120221741 (TGFB2)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    120221741 (TGFB2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    120221741 (TGFB2)
   05144 Malaria
    120221741 (TGFB2)
   05145 Toxoplasmosis
    120221741 (TGFB2)
   05140 Leishmaniasis
    120221741 (TGFB2)
   05142 Chagas disease
    120221741 (TGFB2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    120221741 (TGFB2)
   05321 Inflammatory bowel disease
    120221741 (TGFB2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    120221741 (TGFB2)
   05414 Dilated cardiomyopathy
    120221741 (TGFB2)
   05415 Diabetic cardiomyopathy
    120221741 (TGFB2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    120221741 (TGFB2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hhv04052]
    120221741 (TGFB2)
   00536 Glycosaminoglycan binding proteins [BR:hhv00536]
    120221741 (TGFB2)
Cytokines and neuropeptides [BR:hhv04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   120221741 (TGFB2)
Glycosaminoglycan binding proteins [BR:hhv00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   120221741 (TGFB2)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta CBM96 Beta-prop_RIG_2nd SPEG_u2
Other DBs
NCBI-GeneID: 120221741
NCBI-ProteinID: XP_039075230
LinkDB
Position
Unknown
AA seq 442 aa
MHYCVLSAFLILHLVTAALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEP
EEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSETVCPV
VTTPSGSVGSLCSRHSQVLCGYLDAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFRVF
RLQNPKARVPEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVQEWLH
HKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKSTRK
KNSGKTPHLLLMLLPSYRLESQQSNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGW
KWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILY
YIGKTPKIEQLSNMIVKSCKCS
NT seq 1329 nt   +upstreamnt  +downstreamnt
atgcactactgtgtgctgagcgcttttctgatcctgcatctggtcacggccgcgctcagc
ctgtctacctgcagcacgctcgacatggaccagttcatgcgcaagaggatcgaggcgatc
cgcgggcagatcctcagcaagctgaagctcaccagccccccggaagactatcccgagccc
gaggaggtccccccggaggtgatctccatctacaacagcaccagggacttgctccaggag
aaggcgagccgcagggcggccgcctgcgagcgcgagcggagcgacgaggagtactacgcc
aaggaggtgtacaaaatagacatgccgcccttcttcccctcggaaactgtctgcccagtt
gttacaacaccttctggctctgtgggcagcttgtgttccagacattcccaggtgctctgt
gggtaccttgatgccatcccgcccactttctacagaccttacttcagaattgtccgattt
gacgtctcagcgatggagaagaacgcatccaatttggtgaaagcagagttcagggtcttt
cgtttacagaacccaaaggccagagtgcccgaacaacgcattgaactgtatcagattctc
aaatccaaagatttaacatctccaacccagcgctacattgacagcaaagtcgtgaagaca
agggcagaaggcgaatggctttccttcgatgtgactgacgccgttcaagagtggctccac
cataaagacagaaacctgggatttaaaataagtttacactgtccctgctgcacctttgta
ccatctaataattacatcattccaaataaaagtgaagagctagaagcaagatttgcaggt
attgatggcacctccacatataccagtggtgatcagaaaacaataaagtccactaggaaa
aaaaacagtggcaagaccccacatcttctgctaatgttgttaccctcctacagacttgag
tcacaacagtccaaccggcggaagaagcgtgctttggatgcagcctattgttttagaaat
gtgcaggataattgctgcctgcgtccactttatattgatttcaagagggatcttgggtgg
aaatggattcacgaacctaaagggtacaatgccaacttctgtgcgggagcatgcccgtat
ttgtggagttcagacactcagcacagtagggttctgagcttatataacaccataaatcca
gaagcatccgcatctccttgctgtgtgtcccaggatttagaacccctaaccattctctac
tacatcggcaaaacacccaagatcgaacagctttcaaacatgattgtaaagtcttgcaaa
tgcagctaa

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