Hyaena hyaena (striped hyena): 120221751
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Entry
120221751 CDS
T07257
Symbol
ATR
Name
(RefSeq) serine/threonine-protein kinase ATR isoform X1
KO
K06640
serine/threonine-protein kinase ATR [EC:
2.7.11.1
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv03460
Fanconi anemia pathway
hhv04110
Cell cycle
hhv04115
p53 signaling pathway
hhv04218
Cellular senescence
hhv05165
Human papillomavirus infection
hhv05166
Human T-cell leukemia virus 1 infection
hhv05170
Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09120 Genetic Information Processing
09124 Replication and repair
03460 Fanconi anemia pathway
120221751 (ATR)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
120221751 (ATR)
04115 p53 signaling pathway
120221751 (ATR)
04218 Cellular senescence
120221751 (ATR)
09160 Human Diseases
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
120221751 (ATR)
05170 Human immunodeficiency virus 1 infection
120221751 (ATR)
05165 Human papillomavirus infection
120221751 (ATR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hhv01001
]
120221751 (ATR)
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
hhv03400
]
120221751 (ATR)
Enzymes [BR:
hhv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
120221751 (ATR)
Protein kinases [BR:
hhv01001
]
Serine/threonine kinases: Other
PIKK family [OT]
120221751 (ATR)
DNA repair and recombination proteins [BR:
hhv03400
]
Eukaryotic type
Check point factors
Other check point factors
120221751 (ATR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
N-HEAT_ATR
PI3_PI4_kinase
FAT
M-HEAT_ATR
HEAT_ATR
UME
FATC
HEAT
Mad3_BUB1_I
THP2
Motif
Other DBs
NCBI-GeneID:
120221751
NCBI-ProteinID:
XP_039075246
LinkDB
All DBs
Position
Unknown
AA seq
2644 aa
AA seq
DB search
MGDHGLELASMIPALRELGSASPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTD
SQPTSVMLLDFIQHIMKSSPLMFVNVNGNQGQNEAKGSCIAFSNWIITRLLRIAATPSCH
TLHKKICEVICSLLFLFKSKSPAIFGVLTKELLHLFEDVICVHKRNAVGHFVEWPVVVSQ
FLSQLDEHVGYLQPAPLQFMNMQNLEFIEVTLLIVLIRIIPIVFFRRQELLLWRIGCILL
EYGSPKIKSLAISLSTELFELGGLPAQPASTFFRSFLELLKHLVEMDADQLKLCEEPLSK
LIKTLFPFEAEAYKNIEPVYLNMLLEKLCVMFEDGVLLRLKSDLLKAALCHLLQYFLKYV
PAGYESALQVRKVYVRNICKVLVDALGFQVDAEYLLGPLYAALKMESMEIIEEVHCQIQQ
ENLSSDSDVISSKRRRLSSSLNSSKRPPKQIEEIKHVDMNKKSILWSALKQKGESLQISL
EDGSLKNPVIETLEGIMVILQLTALCTVHCSHQNMNWHNFKDCQQKCEKKPSVVITWMSL
DFYTKVLKSCRNLLESVQKPDLEAVIDKVVKIYDALIYIHIKASFEDHILEDLCGMLSLP
WIHSHSDDGSLKLTTFATNFLALSQRISDSYSPQAESRCVFLLTLFPRRIFLEWRTAVYS
WALQSSHEIIRASCVHGFFILLQQQNSCNRVPKILIDKVKDDSDFVKKEFASILGQLVCT
LHGMFHLTSSLTEPFSQHGPIDLLCKSLKVTSQHECSSSRLKASVCKPFLFLLKKKTPSP
VKLAFIDNLYHLCKHLEFREDETDVKTVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDS
EDGFIKELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLL
SKSASVSGAAYTEIRALVAAKSVKLQNFFSQYKKPICQFLVESLHSSQMTALPSTPCQNA
EMRKQDVAHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTL
GKQLNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHN
ELLLRIGEHYQQVFNGLSILASFASSDDPYQGPREITSPELMADYLQPKLLGILAFFNMQ
LLSSSVGIEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWD
CFVRCLDHAYLGSLLSHVIVALLPLIHIQPKETAAIFHYLIIENRDAVQDFLHEIYFLPD
HPELKKIKAVLQEYREETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQEK
LIKYATDSETVEPVISQLVTVLLKGCQDANSQARLLCGECLGELGAVDPGRLDFSTTESQ
GKDFTFVTGVEDSSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMQTNG
PGHQLWRRFPEHVREILEPHLNTRYKSSQKSTDWSGVKKPIYLSKLGNNFAEWSASWAGY
LITKVRHDLASKVFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLK
HDDQHTISTQDSASDLCQLSTQTVFSMLDHLTQWARHKFQALNAEKFPQSKSNRDKVDSI
VSSVDYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFLQ
KLYAAMHEPDGVAGVSAIRKAEPSLKEQILEHESIGLLRDATACYDRAIQLEPDQIIHYH
GVVKSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKS
TTWSVRLGQLLLSAKKRDITAFYDTLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHML
CELEHSIKPLFHQSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRALLSLNKRPDYN
EMVGECWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQ
KGVELCFPENKTPTESKNMLIHGRAMLLVGRFMEETANFESNAVMKKYKDVTLFLPEWED
GHFYLAKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLSLWLDF
GAKAYEWEKAGRSDRVQMRTDLAKINKVITEHTNQLAPYQFLTAFSQLISRICHSHDEVF
VVLMEIIAKVFLAYPQQAMWMMTAVSKSSYPTRVNRCKEILNKAIHMKKSLEKFVGDATR
LTDKLLELCNKPVDGNSSTLSMSTHFKMLKKLVEEPTFSEILIPLQSVMIPTLPSILGTH
ANHEPFPGHWAYLASFDDTVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLME
FNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVY
MTGKELRQCMLPKAAALSEKLKVFQEFLLPRHPPVFHEWFLRTFPDPTSWYSSRSAYCRS
TAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMV
NGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPLNET
GEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGW
TPYM
NT seq
7935 nt
NT seq
+upstream
nt +downstream
nt
atgggcgaccacggcctggagctggcgtctatgatccccgcgctgcgggagttgggaagt
gccagtccagaggaatataatacagttgtacagaagccaagacaaattctatgtcagttc
attgaccgaatacttacagatgtaaatgttgttgctgtagaacttgtaaagaaaaccgac
tcccagccaacctctgtgatgttgcttgatttcatccagcatataatgaaatcttctcca
cttatgtttgtaaatgtgaatggaaaccaagggcaaaatgaggccaaaggcagttgtatt
gcattcagtaattggatcataacaagacttctgcggattgcagcaactccatcctgtcat
acattacacaagaaaatctgtgaagttatctgctcattattatttctttttaaaagcaag
agtcctgcaatttttggagtactgacaaaggaattactgcatctttttgaagatgtgatt
tgcgtccataaaagaaatgcagtggggcactttgttgaatggccagtggtagtgagccag
tttttaagtcaattagatgaacatgtgggatatttacaaccagctcctttgcaattcatg
aacatgcaaaatttagaatttattgaagttaccttattaatagttcttattcgtattatt
ccaattgtgttttttagaaggcaagaactcttactttggcggataggttgtattctgcta
gagtatggtagtccaaaaattaaatccttagcaattagcctttcaactgaactctttgag
cttggaggattaccagcacaaccagccagcacttttttcaggtcatttttggaattatta
aaacatcttgtagagatggatgcagaccagttgaaactctgtgaagagccattatcaaag
ctgataaaaacactatttccctttgaagcagaagcttataaaaatattgaacctgtctat
ttaaatatgctgctggaaaaactctgtgtcatgtttgaagatggtgtgctattgcggctt
aagtctgatttgctaaaagcagctttgtgccacttactgcagtatttccttaaatatgtg
ccagctgggtatgaatctgctttacaagtcaggaaggtttatgtgagaaacatttgtaaa
gttcttgtggatgcacttggatttcaggtagatgcagagtatttgttgggcccactttat
gctgccttaaagatggaaagtatggaaatcattgaggaagttcattgccaaattcaacag
gaaaacctcagcagtgacagtgatgtaatatcatccaaaaggcgtcgactcagctcatct
ctaaactcttccaaaagaccaccaaaacagattgaggaaattaaacatgtggatatgaac
aaaaagagcattttatggagtgcactgaaacagaaaggtgaatcccttcagatttccctt
gaagatggtagtctaaagaatcctgttatcgagactttagaaggaatcatggtcatccta
caactgactgctctatgtactgttcattgttctcatcaaaacatgaactggcataatttc
aaggactgccaacagaagtgtgagaagaaaccttcagtagtgataacttggatgtctttg
gatttttacacaaaagtgcttaagagctgtaggaatttgttagaatctgttcagaaacct
gacctggaggcagttattgataaagttgtgaaaatatatgatgctctgatttatattcac
ataaaagcttcatttgaagatcatattctggaagatttatgtgggatgctctcacttcca
tggattcattcccattctgatgatggctctttaaagttgactacatttgccactaatttt
ctagcattaagccagaggatttcagatagctactcaccacaggcagagtcacggtgtgtg
tttcttctgactttgtttccaagaagaatattccttgaatggagaacagcagtttatagc
tgggccttacagagctcccatgaaataatccgggctagttgtgttcatggattttttatc
ttattgcagcagcagaattcttgtaacagagttcccaagattcttatagataaagtcaaa
gatgattctgattttgtcaaaaaagaatttgcctctattcttggtcaacttgtctgtact
cttcatggcatgtttcatttgacaagttctttaacagaacctttctctcaacatggaccg
attgacttactctgtaagagcctaaaagtcacttctcaacatgaatgttcatcttcacga
ctaaaagcttctgtttgcaagccatttcttttcctcctgaaaaaaaaaacacctagccca
gtgaaacttgctttcatagataatttatatcatctttgtaagcaccttgaatttagagaa
gatgaaacagatgtaaaaacagttcttggaactttattaaatttaatggaagatccagac
aaggatgttagagtggcttttagtggaaatatcaagcatatattggaatccttggactct
gaagatggatttataaaagagctttttgtcttaagaatgaaggaagcatacacacatgct
caaatctcaagaaataatgagttgaaggataccttgattcttacaacaggggatattgga
agggcagcaaaaggagacttggtaccttttgcacttttgcacttattgcattgtttatta
tccaagtcagcatctgtctctggagcagcatacacggaaatcagagctctggttgcagct
aagagtgttaaactgcaaaactttttcagccagtataagaaacccatctgtcagttttta
gtagaatccctccactccagtcaaatgacagcacttcctagtactccatgccagaatgct
gagatgcggaaacaagatgtggctcaccagagagaaatggctttaaataccttgtctgaa
attgccaatgtttttgactttcctgatcttaatcgtttccttactaggacattacaagtt
ctgctccctgaccttgctgccaaagcaagccctgcagcctctgctctcattcgaacttta
ggaaaacagttaaatgtcaatcgtagagaaattttaataaataacttcaaatatattttt
tctcatttggtttgttcctgttccaaagatgaattagaacgtgcccttcattatctgaag
aatgaaacagaaattgaactaggaagcctattgagacaagatttccaaggattgcataat
gaattattgctacgtattggagaacactatcaacaagttttcaatggtttgtcaatactt
gcatcatttgcatctagtgatgatccatatcagggccccagagaaatcacatctcctgaa
ttaatggctgattatttgcaacctaaattgttgggcattttggccttttttaacatgcag
ttactgagctccagtgttggcattgaagataagaaaatggctttgaacagtttgatgtct
ttgatgaagttgatgggaccaaaacatgtcagttctgtgagagtgaagatgatgaccaca
ctaagaactggcctgagattcaaggatgattttcctgaattgtgttgcagagcttgggat
tgctttgttcgttgcctggatcatgcttatcttggttcccttctcagtcatgtgatagta
gctttgttgcctcttatacacatccagcctaaagaaactgcagctatatttcactacctc
ataattgaaaacagggatgctgtgcaagattttcttcatgaaatatattttttacctgat
catccagaattaaaaaagataaaagcagttctacaggaatacagagaggagacctctgag
agtactgatcttcagacaactcttcaactatccatgaaagcaattcaacatgaaaatgta
gatgttcgtattcatgctcttacaagcttgaaggaaactttgtataaaaatcaggaaaaa
ctgataaaatatgcaacagatagtgaaacagtggaacctgttatctcacagttggtgacg
gtacttttgaaaggttgccaagatgcaaactctcaagctcggttgctctgtggggaatgt
ttaggagaactgggggcagtagatccaggtcgactagatttctcaacaactgaaagccaa
ggaaaagattttacatttgtgactggagtagaagattcaagctttgcctatggattacta
atggaacttacaagagcttaccttgcatatgcagataacagtcgagctcaagattcagct
gcttatgccattcaggagctactttctatttatgactgcagagagatgcagaccaatggc
ccaggtcaccagttgtggaggagatttcctgagcatgttcgggaaatcctggaacctcat
ctaaatactagatataagagttctcagaagtcaacagattggtctggagtaaagaagcca
atttacttaagtaaattaggtaataactttgcagaatggtcagcatcttgggcaggttat
cttataacaaaggttcggcatgatcttgccagtaaagtcttcacctgctgtagcattatg
atgaaacatgatttcaaagtgactatctatcttcttccacatattctagtgtatgtctta
ttgggttgtaatcaagaagatcagcaagaggtttatgcagaaattatggcagttctaaag
catgatgatcagcataccataagtacccaagacagtgcatctgatctgtgtcaactcagt
acacagactgtattctccatgcttgaccatctcacacaatgggcaagacacaaatttcag
gcactgaatgcagagaaatttccacaaagcaaatcaaacagagataaggtagactcaata
gtatcttctgtggattatgaagactatcagagtgtaactcgtttcctagacctcattcct
caggatactctggcagtagcttcctttcgctccaaagcatacacacgagccgtaatgcac
tttgaatcatttattacagaaaagaaacaaaatattcaagagcatcttggatttttacag
aaattgtacgctgctatgcatgaaccggatggagtggctggagtaagcgcaattcgaaag
gcagaaccatccctgaaagaacagatccttgaacacgaaagcattggcttactgagggat
gccactgcttgttatgacagggctattcagctagaaccagaccagattattcattatcat
ggtgtagtgaaatccatgttaggtcttggacagctgtctactgtaatcactcaggtgaac
ggagtgcatgctaacaggtctgaatggacagatgaattaaacacatacagagtggaagca
gcttggaaattgtcacagtgggatttggtggaaaattatttggcagcagatgggaaatct
acaacatggagtgtcagattgggtcagctattattatcagccaaaaaaagagatataaca
gctttttatgacacactgaaactagtaagagcagaacaaattgtacctctttcagctgca
agctttgaaagaggctcctatcaacgaggatatgaatatattgtgagattgcacatgttg
tgtgaattggagcatagcatcaaaccactttttcaccagtcaccaggcgacagctctcaa
gaagattctctaaactgggtagctcgactagaaatgacccagaattcctacagagccaag
gagcccatcctggctctccggagagctttattaagcctcaacaaaagaccagattataat
gaaatggttggagaatgctggctacagagtgccagagttgctaggaaggctggtcaccac
caaacagcctacaatgctctcctaaatgctggagaatcacgacttgctgaactgtatgtg
gaaagggcaaagtggctgtggtccaagggtgatgttcaccaggcactaattgttcttcag
aagggtgttgaattatgttttcctgaaaataaaaccccaaccgagagtaagaacatgtta
atccatggtcgggctatgctactagtgggccgatttatggaagaaacagcgaactttgaa
agcaatgcagttatgaaaaaatataaggacgtaaccttgttcctgccagagtgggaagat
gggcatttttaccttgctaagtactatgacaaattgatgcccatggtcacagacaacaaa
atggaaaagcagggtgatctgattcggtatatagttcttcattttggcagatctctacaa
tatgggaatcagttcatttatcagtctatgccacgaatgttatcactttggcttgatttt
ggtgctaaggcatacgaatgggaaaaagctggccgttctgatcgtgtacaaatgagaact
gatttagctaaaataaacaaggttattacagagcacacaaatcagttagcaccgtatcag
tttttgactgctttttcacagttgatctcccgaatttgtcattctcatgatgaagttttt
gttgtgttgatggaaattatagccaaagtatttctggcctatcctcaacaagcaatgtgg
atgatgacagctgtgtcaaagtcttcttatcccacacgtgtgaacagatgcaaggaaatc
ctaaataaagctattcatatgaaaaaatccttagaaaagtttgttggagatgcaactcgc
ctaacagataagcttctagaattgtgcaataagccggtggatggaaatagctctacatta
agcatgagcactcattttaaaatgcttaaaaagctggtagaagaaccaacatttagtgaa
atcctcattcctttacagtcagtcatgatccctactcttccatcaattctgggtactcat
gccaaccatgagccatttcctgggcattgggcctatcttgcaagctttgatgatacggtg
gaaattcttgcatcccttcagaaaccaaagaagatctctttaaaaggatcagatggaaag
ttctacatcatgatgtgtaagccaaaagatgacctgagaaaggattgtagactgatggaa
tttaattccttaattaataagtgcttgagaaaagatgcagaatctcgcagaagagaactt
catatccgaacatatgcagttattcccctgaatgatgaatgtgggattattgaatgggtt
aacaacactgctggcttgagacctattctgaccaaactatataaggaaaagggagtttat
atgacaggaaaagaacttcgccagtgtatgctaccaaaagctgcagctttgtctgaaaaa
ctcaaagtattccaagaatttctcctacccaggcatcctcctgtttttcatgagtggttt
ctgaggacattccctgatcctacatcatggtacagtagcaggtcagcatactgtcgttcc
accgcagttatgtcaatggttggttatatcctggggcttggagaccgtcatggtgaaaac
atcctctttgattctttgactggtgaatgtgtacatgtggatttcaactgtctcttcaat
aagggagagacctttgaagttccagaaattgttccatttcgactgactcataatatggtt
aatggaatgggtcctatgggaacagagggtctttttcgaagagcttgtgaagttacaatg
aggctgatgcgagatcaaagagagcctttaatgagtgtcttaaaaacttttttacatgat
cctctggtggaatggagtaaaccagtgaaagggcattccaaagcaccactgaatgaaaca
ggggaagttgtcaatgaaaaggccaagacccatgttctggacatcgagcagcgactgcag
ggtgtaatcaagactcgaaatagagtgacagggctgccgttatctattgaaggacatgta
cattaccttatacaagaagctactgatgaaaacttactatgccagatgtaccttggttgg
actccatatatgtga
DBGET
integrated database retrieval system
