Hyaena hyaena (striped hyena): 120222584
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Entry
120222584 CDS
T07257
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv01521
EGFR tyrosine kinase inhibitor resistance
hhv04010
MAPK signaling pathway
hhv04014
Ras signaling pathway
hhv04015
Rap1 signaling pathway
hhv04020
Calcium signaling pathway
hhv04072
Phospholipase D signaling pathway
hhv04144
Endocytosis
hhv04151
PI3K-Akt signaling pathway
hhv04510
Focal adhesion
hhv04540
Gap junction
hhv04630
JAK-STAT signaling pathway
hhv04810
Regulation of actin cytoskeleton
hhv05163
Human cytomegalovirus infection
hhv05200
Pathways in cancer
hhv05206
MicroRNAs in cancer
hhv05214
Glioma
hhv05215
Prostate cancer
hhv05218
Melanoma
hhv05230
Central carbon metabolism in cancer
hhv05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
120222584 (PDGFRA)
04014 Ras signaling pathway
120222584 (PDGFRA)
04015 Rap1 signaling pathway
120222584 (PDGFRA)
04630 JAK-STAT signaling pathway
120222584 (PDGFRA)
04020 Calcium signaling pathway
120222584 (PDGFRA)
04072 Phospholipase D signaling pathway
120222584 (PDGFRA)
04151 PI3K-Akt signaling pathway
120222584 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
120222584 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
120222584 (PDGFRA)
04540 Gap junction
120222584 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
120222584 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
120222584 (PDGFRA)
05206 MicroRNAs in cancer
120222584 (PDGFRA)
05230 Central carbon metabolism in cancer
120222584 (PDGFRA)
05231 Choline metabolism in cancer
120222584 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
120222584 (PDGFRA)
05218 Melanoma
120222584 (PDGFRA)
05215 Prostate cancer
120222584 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
120222584 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
120222584 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hhv01001
]
120222584 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hhv04090
]
120222584 (PDGFRA)
Enzymes [BR:
hhv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
120222584 (PDGFRA)
Protein kinases [BR:
hhv01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
120222584 (PDGFRA)
CD molecules [BR:
hhv04090
]
Proteins
120222584 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
Herpes_gE
DUF3475
Kinase-like
Motif
Other DBs
NCBI-GeneID:
120222584
NCBI-ProteinID:
XP_039076397
LinkDB
All DBs
Position
Unknown
AA seq
1089 aa
AA seq
DB search
MGTSHLALLVSVCLLTGLSPASCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP
MSEEENPNVEVRNEENNSGLFVTVLEVVNASAAHTGLYTCYYNHTQTDEHEIEGRRIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPKTPVTLRSSDGVVHASYDSRQGFNG
TFSVGPYICEATVSGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTILANNISNIVTEVHRRD
RSTVEGRVTFTRVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADESTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKHEEDKLKDWEGSLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccacctggcgctcctggtgtcagtctgtctcctcacagggctgagccca
gcctcctgccagctttcattaccctccatccttcccaacgaaaatgaaaaggtcgtgcag
ctgaattcctccttttctctgcggtgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaagtcagaaatgaggaaaacaacagtggcctt
tttgtgacggtgctggaagtggtcaatgcgtcggcggcccacacggggctgtacacttgc
tattacaaccacactcagacagatgaacatgagatcgaaggcaggcgcatttacatctat
gtcccagacccagatgtagccttcgttcctctaggaatgacggattatttagtcatcgtg
gaggatgatgactctgccattataccttgtcgcacaactgaccccaagactcccgttacc
ttacgcagcagtgacggggtggtccacgcctcctatgacagcagacagggctttaatggg
accttcagcgtcgggccctatatctgcgaagccaccgtcagcgggaagaagttccagacc
attccatttaatgtttatgctttaaaagcaacatcagaacttgatctagaaatggaagcc
cttaaaactgtgtataagtcaggggagacgattgtggtcacctgcgccgtctttaacaac
gaggtggttgaccttcagtggacttaccccggagaagtgaaaggcaaaggcatcacaatg
ctggaggaaattaaggtcccgtccatcaagttggtgtacaccctgacggtccccgaggcc
accgtgaaggacagtggagattatgaatgtgctgcccgccaggccaccaaggaggtcaaa
gagatgaagaaagtcaccatctctgtccatgagaaagggttcattgaaatcaaacccaac
ttcagcccgttggaagctgtggacctgcatgaagttaaacactttgtggtggacgttcag
gcctacccccctcccaggatatcctggctgaaggacaacctaactctgattgaaaatctc
accgagatcaccaccgacatagagaagattcaggaaataagatatcgaagcaaactaaag
ctgatccgtgctaaggaagaagacagtggccattacacgattgtcgttcaaaatgaagat
gacgtgaagagctatactttcgaactcttaactcaagttccctcgtctattctggacttg
gtcgatgaccaccacggctccaccgggggacagactgtgagatgcacagctgaagggaca
cctcttcccgatattgagtggatgatttgcaaggatattaagaaatgtaataacgaaact
tcatggacgattctggccaacaacatctcgaacatcgtcacggaggtccaccgccgggac
aggagtaccgtggagggtcgagtgacattcaccagagtggaggagaccattgccgttcga
tgcctggccaagaatctccttggggccgagaaccgagagctgaagctggtggcccccact
ctgcgttccgaacttacggtggcggctgcggtcctggtgctgctggtgattgtgatcatc
tccctcattgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgttggagg
gtcattgaatcgatcagccctgatggacatgagtatatttacgtggacccaatgcagctg
ccttatgactctcgatgggagtttccgagagatggactagtgcttggtcgcatcctggga
tcgggggcctttgggaaagtggtcgaaggaactgcctacggattgagccggtcccagcct
gtcatgaaagtggcagtgaagatgctaaaacccacagccagatccagtgagaaacaagct
ctcatgtcggaactgaagataatgactcacctagggccgcatttaaacattgtgaacttg
ctgggggcctgtaccaagtcaggccctatttacatcattacggagtactgcttctacggg
gatttggtcaactatttgcataagaatagggacagcttcctgagccgacatccagagaag
ccaaagaaagagttggacatttttgggttgaaccctgctgatgaaagcacacggagttat
gttatcttgtcttttgaaaacaatggtgactacatggacatgaagcaggctgataccaca
cagtacgtccccatgctggaaaggaaagaggtttctaaatactcggacatccagcgatcg
ctgtatgatcgcccagcctcgtataagaagaaatctatgttagactcagaagtcaaaaac
ctcctttcagatgataactcagaaggcctgactttgctggatttgttgagctttacctat
caagttgcgcgaggaatggaatttttggcttccaaaaattgtgtccaccgggacctggct
gctcgaaacgtccttctggcacaagggaaaatcgtgaagatctgtgacttcggcctggcc
agggacatcatgcatgattcaaactacgtgtccaaaggcagtacctttctccctgtgaag
tggatggctcccgagagcatctttgacaacctctacaccacgctgagtgatgtctggtct
tatggcattctgctctgggagatcttttccctcgggggcacaccgtaccctggcatgatg
gtggattccactttctacaacaagatcaagagtggataccggatggccaagcctgaccac
gccaccagtgaagtctatgaaatcatggtcaagtgctggcacagtgagccggagaagaga
ccctccttttaccacctgagtgagattgtggagaatctgttgccaggacagtataagaag
agttacgaaaagattcacctggacttcctgaagagtgaccaccctgccgtggcgcgcatg
cgcgtggactcggacaacgcctacatcggagtcacctacaaacacgaggaagacaagctg
aaggactgggaaggcagcctggatgagcagaggctgagtgcagacagtggctacatcatc
cctctgcccgacatcgaccctgttcctgaggaggaggacctgggcaagaggaacaggcac
agctcgcagacctcagaagagagtgccattgagacaggttccagcagctctaccttcatc
aagagagaggacgaaaccattgaggacatcgatatgatggatgacattggcatagactcc
tcagacctggtagaggacagcttcctgtga
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integrated database retrieval system
