KEGG   Hyaena hyaena (striped hyena): 120222817
Entry
120222817         CDS       T07257                                 
Symbol
NFKB1
Name
(RefSeq) nuclear factor NF-kappa-B p105 subunit isoform X1
  KO
K02580  nuclear factor NF-kappa-B p105 subunit
Organism
hhv  Hyaena hyaena (striped hyena)
Pathway
hhv01523  Antifolate resistance
hhv04010  MAPK signaling pathway
hhv04014  Ras signaling pathway
hhv04024  cAMP signaling pathway
hhv04062  Chemokine signaling pathway
hhv04064  NF-kappa B signaling pathway
hhv04066  HIF-1 signaling pathway
hhv04071  Sphingolipid signaling pathway
hhv04151  PI3K-Akt signaling pathway
hhv04210  Apoptosis
hhv04211  Longevity regulating pathway
hhv04218  Cellular senescence
hhv04380  Osteoclast differentiation
hhv04613  Neutrophil extracellular trap formation
hhv04620  Toll-like receptor signaling pathway
hhv04621  NOD-like receptor signaling pathway
hhv04622  RIG-I-like receptor signaling pathway
hhv04623  Cytosolic DNA-sensing pathway
hhv04625  C-type lectin receptor signaling pathway
hhv04657  IL-17 signaling pathway
hhv04658  Th1 and Th2 cell differentiation
hhv04659  Th17 cell differentiation
hhv04660  T cell receptor signaling pathway
hhv04662  B cell receptor signaling pathway
hhv04668  TNF signaling pathway
hhv04722  Neurotrophin signaling pathway
hhv04917  Prolactin signaling pathway
hhv04920  Adipocytokine signaling pathway
hhv04926  Relaxin signaling pathway
hhv04931  Insulin resistance
hhv04932  Non-alcoholic fatty liver disease
hhv04933  AGE-RAGE signaling pathway in diabetic complications
hhv04936  Alcoholic liver disease
hhv05010  Alzheimer disease
hhv05022  Pathways of neurodegeneration - multiple diseases
hhv05030  Cocaine addiction
hhv05132  Salmonella infection
hhv05133  Pertussis
hhv05134  Legionellosis
hhv05135  Yersinia infection
hhv05140  Leishmaniasis
hhv05142  Chagas disease
hhv05145  Toxoplasmosis
hhv05146  Amoebiasis
hhv05152  Tuberculosis
hhv05160  Hepatitis C
hhv05161  Hepatitis B
hhv05162  Measles
hhv05163  Human cytomegalovirus infection
hhv05164  Influenza A
hhv05165  Human papillomavirus infection
hhv05166  Human T-cell leukemia virus 1 infection
hhv05167  Kaposi sarcoma-associated herpesvirus infection
hhv05168  Herpes simplex virus 1 infection
hhv05169  Epstein-Barr virus infection
hhv05170  Human immunodeficiency virus 1 infection
hhv05171  Coronavirus disease - COVID-19
hhv05200  Pathways in cancer
hhv05202  Transcriptional misregulation in cancer
hhv05203  Viral carcinogenesis
hhv05206  MicroRNAs in cancer
hhv05207  Chemical carcinogenesis - receptor activation
hhv05208  Chemical carcinogenesis - reactive oxygen species
hhv05212  Pancreatic cancer
hhv05215  Prostate cancer
hhv05220  Chronic myeloid leukemia
hhv05221  Acute myeloid leukemia
hhv05222  Small cell lung cancer
hhv05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hhv05321  Inflammatory bowel disease
hhv05415  Diabetic cardiomyopathy
hhv05417  Lipid and atherosclerosis
hhv05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hhv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120222817 (NFKB1)
   04014 Ras signaling pathway
    120222817 (NFKB1)
   04064 NF-kappa B signaling pathway
    120222817 (NFKB1)
   04668 TNF signaling pathway
    120222817 (NFKB1)
   04066 HIF-1 signaling pathway
    120222817 (NFKB1)
   04071 Sphingolipid signaling pathway
    120222817 (NFKB1)
   04024 cAMP signaling pathway
    120222817 (NFKB1)
   04151 PI3K-Akt signaling pathway
    120222817 (NFKB1)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    120222817 (NFKB1)
   04218 Cellular senescence
    120222817 (NFKB1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    120222817 (NFKB1)
   04620 Toll-like receptor signaling pathway
    120222817 (NFKB1)
   04621 NOD-like receptor signaling pathway
    120222817 (NFKB1)
   04622 RIG-I-like receptor signaling pathway
    120222817 (NFKB1)
   04623 Cytosolic DNA-sensing pathway
    120222817 (NFKB1)
   04625 C-type lectin receptor signaling pathway
    120222817 (NFKB1)
   04660 T cell receptor signaling pathway
    120222817 (NFKB1)
   04658 Th1 and Th2 cell differentiation
    120222817 (NFKB1)
   04659 Th17 cell differentiation
    120222817 (NFKB1)
   04657 IL-17 signaling pathway
    120222817 (NFKB1)
   04662 B cell receptor signaling pathway
    120222817 (NFKB1)
   04062 Chemokine signaling pathway
    120222817 (NFKB1)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    120222817 (NFKB1)
   04917 Prolactin signaling pathway
    120222817 (NFKB1)
   04926 Relaxin signaling pathway
    120222817 (NFKB1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    120222817 (NFKB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    120222817 (NFKB1)
  09149 Aging
   04211 Longevity regulating pathway
    120222817 (NFKB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    120222817 (NFKB1)
   05202 Transcriptional misregulation in cancer
    120222817 (NFKB1)
   05206 MicroRNAs in cancer
    120222817 (NFKB1)
   05207 Chemical carcinogenesis - receptor activation
    120222817 (NFKB1)
   05208 Chemical carcinogenesis - reactive oxygen species
    120222817 (NFKB1)
   05203 Viral carcinogenesis
    120222817 (NFKB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    120222817 (NFKB1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    120222817 (NFKB1)
   05221 Acute myeloid leukemia
    120222817 (NFKB1)
   05220 Chronic myeloid leukemia
    120222817 (NFKB1)
   05215 Prostate cancer
    120222817 (NFKB1)
   05222 Small cell lung cancer
    120222817 (NFKB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    120222817 (NFKB1)
   05170 Human immunodeficiency virus 1 infection
    120222817 (NFKB1)
   05161 Hepatitis B
    120222817 (NFKB1)
   05160 Hepatitis C
    120222817 (NFKB1)
   05171 Coronavirus disease - COVID-19
    120222817 (NFKB1)
   05164 Influenza A
    120222817 (NFKB1)
   05162 Measles
    120222817 (NFKB1)
   05168 Herpes simplex virus 1 infection
    120222817 (NFKB1)
   05163 Human cytomegalovirus infection
    120222817 (NFKB1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    120222817 (NFKB1)
   05169 Epstein-Barr virus infection
    120222817 (NFKB1)
   05165 Human papillomavirus infection
    120222817 (NFKB1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    120222817 (NFKB1)
   05135 Yersinia infection
    120222817 (NFKB1)
   05133 Pertussis
    120222817 (NFKB1)
   05134 Legionellosis
    120222817 (NFKB1)
   05152 Tuberculosis
    120222817 (NFKB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    120222817 (NFKB1)
   05145 Toxoplasmosis
    120222817 (NFKB1)
   05140 Leishmaniasis
    120222817 (NFKB1)
   05142 Chagas disease
    120222817 (NFKB1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    120222817 (NFKB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    120222817 (NFKB1)
   05022 Pathways of neurodegeneration - multiple diseases
    120222817 (NFKB1)
  09165 Substance dependence
   05030 Cocaine addiction
    120222817 (NFKB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    120222817 (NFKB1)
   05418 Fluid shear stress and atherosclerosis
    120222817 (NFKB1)
   05415 Diabetic cardiomyopathy
    120222817 (NFKB1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    120222817 (NFKB1)
   04932 Non-alcoholic fatty liver disease
    120222817 (NFKB1)
   04931 Insulin resistance
    120222817 (NFKB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    120222817 (NFKB1)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    120222817 (NFKB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hhv03000]
    120222817 (NFKB1)
Transcription factors [BR:hhv03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    120222817 (NFKB1)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer Ank Ank_2 Ank_4 Ank_3 Ank_5 Death
Other DBs
NCBI-GeneID: 120222817
NCBI-ProteinID: XP_039076751
LinkDB
Position
Unknown
AA seq 972 aa
MAEDDSYLGGPEQMFHLDPLTHTMFNPEIFQPEMPLPTADGPYLQILEQPKQRGFRFRYV
CEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCED
GICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACTKGYNPGLLVHPDLAYLQA
EGGGDRQLTDREKEIIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIY
DSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGIWEGFGDF
SPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQ
RKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGAGSTGPGYGFPHYGFPTYGGITFH
PGTTKSNAGMKHGTIDSPSKNDPESCGKSVDREAVNLSRKVTEPTEQNKEPGTRENELAL
TYTVGGKEENFRFQDDLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENG
DSVLHLAIIHLHAQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEAVVEDLLR
AGADLSLLDRLGNSVLHLAAKEGQDKILSVLLKHRKAALLIDHPNGEGLNAIHIAVMSNS
MACLLLLVAAGADVNAQERKSGRSALHLAVERDNISLAGCLLLEGDAHVDSTTYDGTTPL
HIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWEKDGEDEGVVPGTTPLDMATNWQ
VFDILNGKPYEPEFTSDDLLAQGDMKQLTEDAKLQLYKLLEIPDPDKNWATLAQKLGLGI
LNNAFRLSPAPSKTLMDNYEVSGGTIKELVEALRQMGYTEAIEVIQAAFCAPGTAAPSAA
KTVSHTLSLPLSPASTRPPVDEARDDSICDSGVETSFRKLSFTESLTGGGSLLTLNKVPR
EYAREGPIEGKI
NT seq 2919 nt   +upstreamnt  +downstreamnt
atggcagaagacgattcatatttgggaggacctgaacaaatgtttcatttggatcctttg
actcatacaatgtttaatccagaaatatttcaaccagagatgccactacctacagcagat
ggtccataccttcaaatattagagcaacctaaacagagaggatttcgtttccgttatgta
tgtgaaggcccctcccatggtggactcccaggtgcatctagtgaaaagaacaagaagtcc
taccctcaggtcaaaatctgcaactatgtgggacctgcaaaggttattgttcagttggtc
acaaatggaaaaaacatccacctgcatgcacacagcctggtgggaaaacactgtgaggac
gggatctgcacagtaactgccggacccaaggacatggtggtcggctttgcaaacttaggt
atacttcatgtgacaaagaaaaaggtatttgaaacactggaagcacgaatgacagaggca
tgtacaaagggctacaatcccggacttctggtccatcctgatcttgcctatttgcaagca
gaaggcggaggagaccggcagctcacagatcgggaaaaagagatcatccgccaggcagcc
cttcagcagacgaaggagatggacctcagcgtggtgaggctcatgtttacagcttttctc
ccggatagcaccggcagcttcacgaggcgtctggaacccgtggtgtctgatgccatctat
gacagcaaagcccccaatgcgtccaacttgaaaattgtaagaatggacaggacagctgga
tgtgtaactggaggggaagagatttaccttctctgtgacaaggtgcagaaagatgacatc
caaattcgattttatgaagaggaggaaaatggtggaatctgggaaggatttggagatttt
tctcccacagatgttcatagacaatttgccatcgtcttcaaaactccaaagtataaagat
gtcaacatcacaaaaccagcttccgtgtttgtccaacttcggaggaaatctgatttggaa
actagcgaacccaaaccttttctctactaccctgaaatcaaagataaagaggaagtgcag
aggaaacggcagaagctcatgcctaatttctcagatagtttcggcggcggtagtggtgcc
ggagctggaggcggaggcatgtttggcagtggcggtggaggagggggtgctggaagtacg
ggtccagggtatggcttcccccactatggattccctacatacggtggaattaccttccat
cctggaaccactaaatctaatgctgggatgaaacatggaaccatagactccccatctaaa
aatgatcctgagagttgtggcaagagtgtggacagagaggcagtgaacctctctaggaaa
gtaactgaacccacagaacaaaataaggagcctggcactagagaaaatgagcttgccctg
acgtatacagtaggaggaaaggaagagaacttcaggtttcaggatgacctcttcctagag
aaggctatgcagctggccaagcggcatgccaatgccctttttgactacgcggtgacagga
gatgtgaagatgctgctggctgtccagcgccatctcactgcagtgcaggatgagaatggg
gacagtgtcttacacttagcaatcatccatcttcatgctcagcttgtgagggacctacta
gaagtcacatctggtttgatttctgatgacattatcaatatgagaaatgatctctaccag
acacccttgcacttggccgtgatcaccaagcaggaggctgtggtggaggacttgctgagg
gccggggccgacctgagcctcctggaccgcttgggtaactctgttttgcacctagctgcc
aaagaaggacaagacaaaattctcagtgttttactcaagcacagaaaggcagcactactt
atcgaccaccctaacggggaaggtctaaacgccattcacatagccgtgatgagcaacagc
atggcgtgtctgctgctgctggtggccgccggggctgacgtcaatgcacaggagcggaag
tcggggcgctcggcgctgcacctggctgtggagcgtgacaacatctctcttgctggctgc
ctgctcctggagggtgatgcccatgtagacagtaccacgtatgatggaaccacacccctg
cacatagcagccgggagagggtccaccaggctggcggctcttctcaaagcagcaggcgca
gatcccctcgtggagaactttgagcctctctatgacctggatgactcttgggaaaaagat
ggagaggatgaaggagtcgtgcctggaaccacacccctagatatggccaccaactggcag
gtgttcgatatattaaatgggaaaccgtatgagccagagtttacatctgatgatttactc
gcacaaggagacatgaaacagctgactgaagatgccaagttgcagctctacaagttgcta
gaaatccctgatccagacaaaaactgggctaccctggcacagaaattaggtctggggata
ctaaataacgccttccggctgagtcccgctccttctaaaactctcatggacaactacgag
gtctctggggggacaataaaagagctagtggaggccctgagacagatgggctataccgaa
gccatcgaagtgatccaggctgccttctgcgccccaggaactgcagcccccagtgcagcg
aagactgtctctcacaccctctcgctgcctctctcgcctgcctccacgaggccaccagta
gacgaggcccgggacgacagcatctgtgacagcggcgtggagacctccttccgcaaactc
agctttacagagtctctgaccggcggcggctccttgctgactcttaacaaagtgccccgc
gagtacgcgcgggaaggacctatcgaaggcaaaatctag

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