Hyaena hyaena (striped hyena): 120224519
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Entry
120224519 CDS
T07257
Symbol
POLE
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv03030
DNA replication
hhv03410
Base excision repair
hhv03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
120224519 (POLE)
03410 Base excision repair
120224519 (POLE)
03420 Nucleotide excision repair
120224519 (POLE)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
hhv03032
]
120224519 (POLE)
03400 DNA repair and recombination proteins [BR:
hhv03400
]
120224519 (POLE)
Enzymes [BR:
hhv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
120224519 (POLE)
DNA replication proteins [BR:
hhv03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
120224519 (POLE)
DNA repair and recombination proteins [BR:
hhv03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
120224519 (POLE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DUF1744
POL2_thumb
DNA_pol_B_exo1
zf_DPOE_2
zf-DPOE
DNA_pol_B
DNA_pol_B_exo2
RNase_H_2
APP_N
Motif
Other DBs
NCBI-GeneID:
120224519
NCBI-ProteinID:
XP_039078689
LinkDB
All DBs
Position
Unknown
AA seq
2240 aa
AA seq
DB search
MDMRFGFERLKEPGEKTGWLINMHPTEILDEDKRLVSAVDYYFIQDDGSRFKVALPYKPY
FYIATRKGCEREVSSFLSKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIKLSFNTVEDL
VRVRKDISPAVKKNREQSHASDAYTAMLSSVLQGASVVVDDEEASKKVTDQLDNIVDMRE
YDVPYHIRLSIDLKIHVAHWYNVRYRGNALPVEITRRDDLVERPDPVVLAFDIETTKLPL
KFPDAETDQIMMISYMIDGQGYLITNREIVSEDIGDFEFTPKPEYEGPFCVFNEPDEVHL
IQRWFEHVQETKPTIMVTYNGDFFDWPFVEARAAVHGLSMYQEIGFQKDSQGEYRAPQCI
HMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDA
VATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQE
FNKLTDDGHVLDAETYVGGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMRHAIE
EEEKVPMEQVTNFQEVCDQIKTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPS
AVVDEATCAACDFNKPGADCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLTAEGP
ARAFHELSREEQAKYEKRRLTDYCRKAYKKIHVTRVEERLTTICQRENSFYVDTVRAFRD
RRYEFKGLHKVWKKKLSAAMEVGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRRG
ARWYSMEMAGIVCFTGANIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVIKTTSV
KKPKVTISYPGAMLNIMVKEGFTNDQYQELTEPSSLTYVTRSENSIFFEVDGPYLAMILP
ASKEEGKKLKKRYAVFNEDGSLAELKGFEIKRRGELQLIKIFQSSVFEAFLKGSTLEEVY
GSVAKVADYWLDVLYSKAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEF
LGDQMVKDAGLSCRYIISRKPEGSPVTERAVPLAIFQAEPMVRKHFLRKWLKSSSLQDFD
IRTILDWDYYIERLGSAIQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDICKQKKI
SELFVLEGRRQVGVAQAPESSESLGAPDMEDFGLVKPLHSAVPVATKRKRVLWESQEESQ
DLELAVPWQEVLGAPPALGTTQEEWLVWLRFHKKKWQLQARQRLAHKKRRRLEVAEGDPR
PGAVRERPAAGLGGFLRRTARSILDLPWQIVQISETSQAGLFRLWAVISSDLHCIKLNIP
RRFYVNQRVAKAEEGPSYRKVSRVLPRSNMVHNLYEYSVPEDMYQEHINEINTELSAPDI
EGVYETQVPLLFRALVQLGCVCVVNKQLVRHLSGREAETFALEHLEMRSLAQFSYLEPGS
IRHLYLYHHAQGHKALFGLFVPSQRKACVFVLDTVRSNQMPGLSTLYSAEHGLLMEKVGP
ELLPPPKHTFEVRAETDLKTICRAIQRFLLAYKEERRGPTLIAVQSNWELKSLAGEVPVL
EEFPLVPVHVADRISYGVLDWQRLGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPED
ISTFGSDLFFARHLQRHNHLLWLSPTARPDLGGKEADDNRLVMEFDDQASVEINCPGCYS
TVCVELDIQNLAVNTILQSHHINDMEGADSVGVSFDVIQQASLEDMITGNQAAGTPASYD
ETALCSSTFRILKSMVVGWVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHS
MMKKLFLQLIAEFKRLGSSVVYANFNRIILCTKKRRIADAIAYVEYITNSIHSKEIFHSL
TISFSRCWEFLLWMDPSNYGGIKGNVPSSVHCGQQDSQKEGGGEEEEESGEEEEQEEEEG
AQEPDVEDMLENSWSIVHFLPQAASCQSYFLMIVSAYIVAVYHSMKEELRRSAPGSTPVR
RRGPSQLSQEAQAVAGALPGMITFSQDYVANELTQNFFTITQKIQKKVTGSRNSTELSEM
FPVLPGSHLLLNNPALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRD
PCRSYVLPEVICRSCNFCRDLDLCREPSFSQDGAVLPRWLCSNCQVAYDSSVIEMALVEA
VQKKLMAFTLQDLICLKCRGVKETNMPVYCGCAGDFALTIRTKVFMDQIRIFQNIAQHYG
MSYLMETLEWLLQKSPQLGH
NT seq
6723 nt
NT seq
+upstream
nt +downstream
nt
atggatatgcggtttggttttgagagactcaaggagcctggtgagaagacgggctggctc
atcaacatgcaccctaccgagattttagatgaagataaacgcctagtcagcgccgtggat
tactactttattcaggatgatgggagcagatttaaggtggccttgccctacaagccgtat
ttctacattgcaaccagaaagggttgcgagcgagaagtttcatcttttctgtccaagaag
tttcagggtaaaattgctaaagtagagactgtgcccaaagaggacctggacttgccaaat
cacttggtgggtttgaagcggaattacattaaactgtccttcaacacagtagaggacctt
gtcagagtgaggaaggacatctcccctgctgtgaagaagaatcgggagcaaagccatgcc
agtgatgcctacacagctatgctctccagtgttctgcaaggggccagtgtggtggttgac
gacgaggaagcctctaagaaggtcaccgaccagttggacaacatcgtggacatgcgggag
tatgatgtgccctaccacatccgcctctccattgacctgaagatccatgtggctcactgg
tacaacgtcaggtaccgaggaaacgccctccctgtggaaatcacccgccgagatgacctt
gttgaacgacctgaccctgtggttttggcatttgacatcgagacaaccaaactgcccctc
aagtttcctgacgctgagaccgaccagattatgatgatttcctatatgattgacggtcaa
ggctacctcatcaccaacagggagattgtgtcagaggacattggagattttgagttcacc
cccaagccagagtatgagggacccttctgtgtcttcaatgaacccgatgaggttcatcta
atccagaggtggtttgaacatgtccaagagacaaaacccaccatcatggtcacctacaat
ggagacttttttgactggccgtttgtggaggccagagcagcagtccatgggctgagcatg
taccaggagatagggttccagaaggacagccaaggggagtacagggcgccccagtgcatc
cacatggactgcctcaggtgggtgaagagggacagttacctccctgtgggcagccacaac
ctcaaggcagctgccaaagccaagctgggctacgaccctgtggagctggaccccgaagac
atgtgccggatggccactgagcagccccagactctggccacgtactcggtgtcagacgca
gtggccacgtactacctgtacatgaagtacgtccaccccttcatattcgccctctgcacc
attatccccatggagcccgatgaggtgctccggaagggctccgggacgctgtgcgaggcc
ttgttgatggtgcaggccttccatgccaacatcatcttccccaacaagcaggaacaggag
tttaacaagctgactgacgatggccatgtgctggacgccgagacctacgtgggtggccac
gtggaggccctggaatcgggcgtgttccgcagtgacatcccctgccggttcaggatgaat
cccgctgcctttgactttctgctgcagcgggtggagaagaccatgcgtcatgccatcgag
gaagaggagaaggtgcccatggagcaggtcacaaacttccaagaggtatgtgatcagatt
aagaccaagctcacctccctgaaggatgttccaaacagaatcgagtgtccccttatctac
cacctggatgtgggggccatgtaccccaacatcatcctgacaaaccgcctgcagccctct
gccgtggtggacgaggccacctgtgctgcctgtgacttcaacaagcctggagcagactgc
cagaggaagatggcctggcagtggaggggcgagttcatgccagccagtcgcagcgagtac
catcggatccagcaccagctggagtcagagaagttccctcccttgactgcagagggccca
gcccgggcctttcacgagctgtcccgcgaggagcaggctaaatatgagaagcggaggctg
acagattactgccggaaggcctacaagaagatccacgtgaccagggtggaggagcgcctc
accaccatctgtcagcgggagaactccttctatgtggacacggtgcgcgccttccgggac
aggcgctatgagttcaagggtctccacaaggtctggaagaagaagctgtccgcggccatg
gaggtgggcgacgcggccgaggtgaagcgctgcaagaacatggaggttctgtacgactcc
ctgcagctggcgcacaagtgcatcctgaactccttctacggctacgtcatgcgcagaggg
gctcgctggtactccatggagatggcaggcattgtctgcttcacaggagccaacatcatc
acccaggcgcgggagctgatcgagcagatcgggaggcccttagagctggacacagacgga
atatggtgcgtcctgcccaacagcttccctgaaaactttgtcatcaagacgaccagtgta
aaaaaacccaaggtgaccatctcctaccctggggccatgttaaatatcatggtcaaggaa
ggcttcaccaatgatcaataccaggagctgactgagccgtcctcactcacctatgtcacc
cgctcagagaatagcatcttttttgaagttgatggaccctaccttgccatgatccttcca
gcctccaaggaagagggcaagaaactgaagaagagatacgctgtcttcaatgaggacggt
tccctggctgagctaaagggcttcgagatcaaacgccggggggagctgcagctgattaag
atcttccagtcttcagtgttcgaggccttcctcaagggcagcaccctagaagaagtgtat
ggctctgtcgccaaggtggctgactactggctggatgtgctgtatagtaaggctgcaaac
atgcctgattctgagctgtttgagctgatctctgagaaccgctccatgtctcggaagctg
gaagattatggggagcagaagtccacgtctatcagcacagccaagcgtctggctgagttc
ctgggggatcagatggtgaaggacgcagggctgagctgccgctacatcatctcccggaag
cccgagggctctccggtcacagagagggccgtcccacttgccattttccaggcagagccc
atggtgaggaagcattttctccggaaatggcttaagagttcttctctccaagattttgat
attcggacgatcctggattgggactactacattgagcggctggggagtgccatacagaag
atcatcacaatccctgcggccctacagcaggtgaagaacccagtgccacgtgtcaagcac
cctgactggctgcacaagaaacttttggagaagaatgacatctgcaagcagaagaagatc
agtgagctcttcgtcctcgaaggcaggagacaggtgggcgtggcccaggctccagaaagc
tcggagagcctcggtgctcctgacatggaggattttggcctggtgaagccactgcactca
gcggttcctgttgccaccaagaggaagcgtgtcctctgggagagccaggaggagtcgcag
gacctggagctggcagtgccctggcaggaggtcttgggggcgcctcctgccctcgggacc
acgcaggaagagtggctggtctggctccggttccacaagaagaagtggcagctgcaggcc
cggcagcgcctggctcacaagaagaggcggcgtctggaggtggcagagggcgaccctcgg
cctggggctgtccgcgaaaggcccgccgctgggctggggggcttcttgcgaagaaccgcc
cgcagcattttggacctcccgtggcagattgtgcagatcagtgagactagccaggccggc
ttgttcaggctgtgggccgtcatcagcagtgacttacactgtatcaaactgaacatcccc
cgccggttctacgttaaccagcgggtagctaaagccgaggaggggccttcataccgcaag
gtcagtcgagtgcttcctcgctccaacatggtccacaatctctacgagtactcggtgccc
gaggatatgtaccaggaacatatcaatgagatcaatactgaattgtcggccccagacatc
gagggtgtatacgagacgcaggttccgttattgttccgggccctggtgcagctgggctgt
gtgtgtgtcgtcaataaacagctggtgagacacctttcgggccgggaagccgaaaccttc
gctcttgagcacctggagatgcgctctctggcccagttcagctacctggaaccagggagc
atccgccacctctacctgtaccaccacgcacagggccacaaggcgctctttggcttattt
gtgccctcccagcgcaaggcatgcgtgttcgtgctggacaccgtgcgaagcaaccagatg
cccggcctcagcaccctgtactcggctgagcatggcctcctgatggagaaggtgggcccc
gaactcctgcctccccctaaacacacttttgaagttcgggctgaaactgacttgaaaacc
atctgcagagccatccagcgcttcctgctggcctacaaggaggagcgccgtgggcccaca
ctcatcgctgttcagtccaactgggagctgaagagcctggctggcgaggtgcccgtcctg
gaggaattcccgctggtgcctgtccacgtggcggacaggatcagctatggagtcctggac
tggcagcgcctcggagcccggcgcatgatccgccactacctcaacctggacacctgcctg
tcccaggccttcgagatgagcaggtactttcatatccccattgggaacctgcctgaggac
atctccaccttcggctccgacctcttctttgcccgccacctgcagcgccacaaccacctg
ctctggctgtcccccacagcgcgccccgacctgggcggcaaggaggccgatgacaatcgc
ctcgtcatggagttcgacgaccaggccagcgtggagatcaactgtccaggctgctactcc
acggtgtgcgtggagctggacatccagaacctggctgtcaacaccatcttgcagtcccac
cacatcaatgacatggagggggctgacagcgtgggcgtcagcttcgacgtgatccagcag
gcctccctggaggacatgatcactggcaatcaggccgccggcacccccgccagctacgac
gagacagctctctgctccagcactttcaggatcctgaagagcatggtggtgggctgggtg
aaggagatcacacagtaccacaacatctacgccgacaaccaggtgatgcacttttaccgc
tggctccggtccccatcctcactgctgcacgaccctgccctgcaccgcacactccacagc
atgatgaagaagctcttcttgcagctcattgccgagttcaagcgcttggggtcctctgtc
gtctatgccaacttcaaccgcatcatcctctgcacgaagaagcggcggatcgcagacgcc
attgcctacgtggagtacatcaccaacagcatccattctaaagagatcttccactccttg
acgatttctttctctcggtgctgggaatttcttctctggatggacccgtctaactacggt
ggaatcaaaggaaacgttccatccagtgttcactgtggacagcaagactcccaaaaagaa
ggcgggggggaggaggaggaggaaagcggggaggaggaggagcaggaggaggaggaaggc
gcccaggagccggacgtggaggacatgctggaaaacagctggagcatcgtgcacttcctg
ccacaggcagcctcctgccagagctacttcctcatgatagtttcagcgtacattgtggcc
gtgtaccacagcatgaaggaggagctgaggcgcagcgccccagggagcacccccgtgcgg
aggagggggcccagccagctctcccaagaggcccaggcagtggccggagccctccctgga
atgatcaccttctctcaagattatgtggcaaatgaactcacccagaacttcttcaccatc
actcaaaagattcagaagaaagtcacgggctctcggaactccactgagctctcggaaatg
tttcctgtcctccctggttctcacttgctgctcaataaccctgctttggagttcatcaaa
tacgtgtgcaaggttctgtctctggacacgaacatcacaaatcaggtgaacaagctgaac
cgggacctgctgcgcctggtggacgttggcgagttctcagaggaggcccagttccgagac
ccctgccgttcctacgtgctccctgaggtcatctgccgcagctgtaatttctgccgggac
ctggacctgtgcagagagccctccttctctcaggacggggctgtgctgcctcggtggctc
tgctccaactgtcaggttgcctatgactcatcagtcattgagatggccctggtggaagcc
gtgcagaagaaactgatggccttcactctgcaggacctgatctgcctcaagtgccggggt
gtgaaggagaccaacatgcctgtgtactgtggctgtgccggggactttgccctcaccatc
cgcaccaaggtcttcatggaccagattagaatcttccagaacattgcccagcactatggc
atgtcatacctcatggagaccctggagtggctgctgcagaagagccctcagctgggccat
tag
DBGET
integrated database retrieval system
