KEGG   Hyaena hyaena (striped hyena): 120227958
Entry
120227958         CDS       T07257                                 
Symbol
RAC1
Name
(RefSeq) ras-related C3 botulinum toxin substrate 1 isoform X1
  KO
K04392  Ras-related C3 botulinum toxin substrate 1
Organism
hhv  Hyaena hyaena (striped hyena)
Pathway
hhv04010  MAPK signaling pathway
hhv04014  Ras signaling pathway
hhv04015  Rap1 signaling pathway
hhv04024  cAMP signaling pathway
hhv04062  Chemokine signaling pathway
hhv04071  Sphingolipid signaling pathway
hhv04145  Phagosome
hhv04148  Efferocytosis
hhv04151  PI3K-Akt signaling pathway
hhv04310  Wnt signaling pathway
hhv04360  Axon guidance
hhv04370  VEGF signaling pathway
hhv04380  Osteoclast differentiation
hhv04510  Focal adhesion
hhv04520  Adherens junction
hhv04530  Tight junction
hhv04613  Neutrophil extracellular trap formation
hhv04620  Toll-like receptor signaling pathway
hhv04650  Natural killer cell mediated cytotoxicity
hhv04662  B cell receptor signaling pathway
hhv04664  Fc epsilon RI signaling pathway
hhv04666  Fc gamma R-mediated phagocytosis
hhv04670  Leukocyte transendothelial migration
hhv04722  Neurotrophin signaling pathway
hhv04810  Regulation of actin cytoskeleton
hhv04932  Non-alcoholic fatty liver disease
hhv04933  AGE-RAGE signaling pathway in diabetic complications
hhv04972  Pancreatic secretion
hhv05014  Amyotrophic lateral sclerosis
hhv05020  Prion disease
hhv05022  Pathways of neurodegeneration - multiple diseases
hhv05100  Bacterial invasion of epithelial cells
hhv05132  Salmonella infection
hhv05135  Yersinia infection
hhv05163  Human cytomegalovirus infection
hhv05167  Kaposi sarcoma-associated herpesvirus infection
hhv05169  Epstein-Barr virus infection
hhv05170  Human immunodeficiency virus 1 infection
hhv05200  Pathways in cancer
hhv05203  Viral carcinogenesis
hhv05205  Proteoglycans in cancer
hhv05208  Chemical carcinogenesis - reactive oxygen species
hhv05210  Colorectal cancer
hhv05211  Renal cell carcinoma
hhv05212  Pancreatic cancer
hhv05231  Choline metabolism in cancer
hhv05415  Diabetic cardiomyopathy
hhv05416  Viral myocarditis
hhv05417  Lipid and atherosclerosis
hhv05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hhv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120227958 (RAC1)
   04014 Ras signaling pathway
    120227958 (RAC1)
   04015 Rap1 signaling pathway
    120227958 (RAC1)
   04310 Wnt signaling pathway
    120227958 (RAC1)
   04370 VEGF signaling pathway
    120227958 (RAC1)
   04071 Sphingolipid signaling pathway
    120227958 (RAC1)
   04024 cAMP signaling pathway
    120227958 (RAC1)
   04151 PI3K-Akt signaling pathway
    120227958 (RAC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    120227958 (RAC1)
   04148 Efferocytosis
    120227958 (RAC1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    120227958 (RAC1)
   04520 Adherens junction
    120227958 (RAC1)
   04530 Tight junction
    120227958 (RAC1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    120227958 (RAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    120227958 (RAC1)
   04620 Toll-like receptor signaling pathway
    120227958 (RAC1)
   04650 Natural killer cell mediated cytotoxicity
    120227958 (RAC1)
   04662 B cell receptor signaling pathway
    120227958 (RAC1)
   04664 Fc epsilon RI signaling pathway
    120227958 (RAC1)
   04666 Fc gamma R-mediated phagocytosis
    120227958 (RAC1)
   04670 Leukocyte transendothelial migration
    120227958 (RAC1)
   04062 Chemokine signaling pathway
    120227958 (RAC1)
  09154 Digestive system
   04972 Pancreatic secretion
    120227958 (RAC1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    120227958 (RAC1)
  09158 Development and regeneration
   04360 Axon guidance
    120227958 (RAC1)
   04380 Osteoclast differentiation
    120227958 (RAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    120227958 (RAC1)
   05205 Proteoglycans in cancer
    120227958 (RAC1)
   05208 Chemical carcinogenesis - reactive oxygen species
    120227958 (RAC1)
   05203 Viral carcinogenesis
    120227958 (RAC1)
   05231 Choline metabolism in cancer
    120227958 (RAC1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    120227958 (RAC1)
   05212 Pancreatic cancer
    120227958 (RAC1)
   05211 Renal cell carcinoma
    120227958 (RAC1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    120227958 (RAC1)
   05163 Human cytomegalovirus infection
    120227958 (RAC1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    120227958 (RAC1)
   05169 Epstein-Barr virus infection
    120227958 (RAC1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    120227958 (RAC1)
   05135 Yersinia infection
    120227958 (RAC1)
   05100 Bacterial invasion of epithelial cells
    120227958 (RAC1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    120227958 (RAC1)
   05020 Prion disease
    120227958 (RAC1)
   05022 Pathways of neurodegeneration - multiple diseases
    120227958 (RAC1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    120227958 (RAC1)
   05418 Fluid shear stress and atherosclerosis
    120227958 (RAC1)
   05415 Diabetic cardiomyopathy
    120227958 (RAC1)
   05416 Viral myocarditis
    120227958 (RAC1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    120227958 (RAC1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    120227958 (RAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hhv04131]
    120227958 (RAC1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hhv04147]
    120227958 (RAC1)
   04031 GTP-binding proteins [BR:hhv04031]
    120227958 (RAC1)
Membrane trafficking [BR:hhv04131]
 Exocytosis
  Small GTPases and associated proteins
   Rho GTPases
    120227958 (RAC1)
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    120227958 (RAC1)
  Macropinocytosis
   Ras GTPases
    120227958 (RAC1)
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    120227958 (RAC1)
Exosome [BR:hhv04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   120227958 (RAC1)
  Exosomal proteins of other body fluids (saliva and urine)
   120227958 (RAC1)
  Exosomal proteins of colorectal cancer cells
   120227958 (RAC1)
  Exosomal proteins of bladder cancer cells
   120227958 (RAC1)
GTP-binding proteins [BR:hhv04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    120227958 (RAC1)
SSDB
Motif
Pfam: Ras Roc Arf CagD
Other DBs
NCBI-GeneID: 120227958
NCBI-ProteinID: XP_039081963
LinkDB
Position
Unknown
AA seq 211 aa
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPVADVFLICFSLVSPASFENVRAKWYPEV
RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT
QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
NT seq 636 nt   +upstreamnt  +downstreamnt
atgcaggccatcaagtgtgtggtggtgggagacggagctgtaggtaaaacgtgcctactt
atcagttacacaaccaatgcatttcctggagaatatatccccactgtttttgacaactac
tctgccaacgttatggtggatggaaaaccggtgaatctgggcttatgggacacagctgga
caagaagattatgacagattacgtcccttatcctatccgcaaacagttggagaaacgtat
ggtaaggatataacctccaggggcaaagacaagccggttgccgatgtattcctaatttgc
ttttctcttgtgagtcctgcatcatttgaaaatgttcgagcaaagtggtaccctgaagtg
cgacaccactgtcccaacacccccatcatcttggtgggaaccaaacttgacctcagggac
gacaaagacacgattgaaaaactgaaggagaagaagctgactcccatcacctacccgcag
ggtttggccatggccaaggagatcggtgctgtaaaatacctggagtgctcggcgctcacg
cagcgaggcctcaagacagtgtttgatgaagccattcgagcagttctgtgcccccctccc
gtcaagaagaggaagagaaaatgcctgctgttgtaa

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