KEGG   Hyaena hyaena (striped hyena): 120228759
Entry
120228759         CDS       T07257                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
hhv  Hyaena hyaena (striped hyena)
Pathway
hhv04010  MAPK signaling pathway
hhv04015  Rap1 signaling pathway
hhv04218  Cellular senescence
hhv04620  Toll-like receptor signaling pathway
hhv04664  Fc epsilon RI signaling pathway
hhv04668  TNF signaling pathway
hhv04714  Thermogenesis
hhv04750  Inflammatory mediator regulation of TRP channels
hhv04912  GnRH signaling pathway
hhv04935  Growth hormone synthesis, secretion and action
hhv04936  Alcoholic liver disease
hhv05014  Amyotrophic lateral sclerosis
hhv05022  Pathways of neurodegeneration - multiple diseases
hhv05132  Salmonella infection
hhv05135  Yersinia infection
hhv05145  Toxoplasmosis
hhv05161  Hepatitis B
hhv05169  Epstein-Barr virus infection
hhv05170  Human immunodeficiency virus 1 infection
hhv05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hhv05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hhv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120228759 (MAP2K3)
   04015 Rap1 signaling pathway
    120228759 (MAP2K3)
   04668 TNF signaling pathway
    120228759 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    120228759 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    120228759 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    120228759 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    120228759 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    120228759 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    120228759 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    120228759 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    120228759 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    120228759 (MAP2K3)
   05161 Hepatitis B
    120228759 (MAP2K3)
   05169 Epstein-Barr virus infection
    120228759 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    120228759 (MAP2K3)
   05135 Yersinia infection
    120228759 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    120228759 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    120228759 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    120228759 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    120228759 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    120228759 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hhv01001]
    120228759 (MAP2K3)
Enzymes [BR:hhv01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     120228759 (MAP2K3)
Protein kinases [BR:hhv01001]
 Serine/threonine kinases: STE group
  STE7 family
   120228759 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 Choline_kinase APH RIO1 DUF4344
Other DBs
NCBI-GeneID: 120228759
NCBI-ProteinID: XP_039083282
LinkDB
Position
Unknown
AA seq 347 aa
MESPASSQPSSMPPTKGKSKRKKDLRISCMSKPPAPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTLDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADSFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcccgcctccagtcaaccctccagcatgcccccgaccaaagggaaatccaag
aggaagaaggatttacggatatcctgcatgtccaagccgcctgcacccaaccctacaccc
ccccggaacctggactctcggaccttcattaccatcggagacaggaactttgaggtggag
gccgatgacctggtgaccatctcggagctgggccgtggagcctatggggtggtggagaag
gtgcggcacgcccagagtggcaccatcatggccgttaaacggatccgggccactgtgaac
tcacaggagcagaagcgtctgctcatggacttggacatcaacatgcggacagtcgactgc
ttctacactgtcaccttctacggggccctcttcagagagggcgatgtgtggatctgcatg
gagctcatggacacgtccctggacaagttctaccggaaagtgcttgataaaaacatgacc
attcccgaggacatcctgggggagattgctgtgtctatcgtccgggcgctggagcatctg
cacagcaagctgtccgtgatccacagagatgtgaagccgtccaatgtcctcatcaataag
gagggtcacgtgaagatgtgcgacttcgggattagtggctatttggtggattctgtggcc
aagacgctggatgctggctgcaagccctacatggctcctgagagaatcaacccggagctg
aaccagaagggctacaacgtcaagtctgacgtctggagcctcggcatcaccatgatcgag
atggccattctccggtttccttatgagtcctgggggaccccgttccagcagctgaaacag
gtggtggaggagccatcccctcagctcccggccgactcgttctcccctgagtttgtggac
ttcactgcacagtgcctgaggaagaaccccgcagagcgcatgagctacctggagctgatg
gagcaccctttcttcaccttgcacaaaaccaagaagacggacattgctgcctttgtgaag
gagatcctgggggaggactcgtag

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