KEGG   Hyaena hyaena (striped hyena): 120229394
Entry
120229394         CDS       T07257                                 
Symbol
RHOA
Name
(RefSeq) transforming protein RhoA
  KO
K04513  Ras homolog gene family, member A
Organism
hhv  Hyaena hyaena (striped hyena)
Pathway
hhv04014  Ras signaling pathway
hhv04015  Rap1 signaling pathway
hhv04022  cGMP-PKG signaling pathway
hhv04024  cAMP signaling pathway
hhv04062  Chemokine signaling pathway
hhv04071  Sphingolipid signaling pathway
hhv04072  Phospholipase D signaling pathway
hhv04081  Hormone signaling
hhv04144  Endocytosis
hhv04150  mTOR signaling pathway
hhv04270  Vascular smooth muscle contraction
hhv04310  Wnt signaling pathway
hhv04350  TGF-beta signaling pathway
hhv04360  Axon guidance
hhv04510  Focal adhesion
hhv04520  Adherens junction
hhv04530  Tight junction
hhv04611  Platelet activation
hhv04621  NOD-like receptor signaling pathway
hhv04625  C-type lectin receptor signaling pathway
hhv04660  T cell receptor signaling pathway
hhv04670  Leukocyte transendothelial migration
hhv04722  Neurotrophin signaling pathway
hhv04810  Regulation of actin cytoskeleton
hhv04921  Oxytocin signaling pathway
hhv04928  Parathyroid hormone synthesis, secretion and action
hhv04972  Pancreatic secretion
hhv05100  Bacterial invasion of epithelial cells
hhv05132  Salmonella infection
hhv05133  Pertussis
hhv05135  Yersinia infection
hhv05152  Tuberculosis
hhv05163  Human cytomegalovirus infection
hhv05200  Pathways in cancer
hhv05203  Viral carcinogenesis
hhv05205  Proteoglycans in cancer
hhv05206  MicroRNAs in cancer
hhv05210  Colorectal cancer
hhv05417  Lipid and atherosclerosis
hhv05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hhv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    120229394 (RHOA)
   04015 Rap1 signaling pathway
    120229394 (RHOA)
   04310 Wnt signaling pathway
    120229394 (RHOA)
   04350 TGF-beta signaling pathway
    120229394 (RHOA)
   04072 Phospholipase D signaling pathway
    120229394 (RHOA)
   04071 Sphingolipid signaling pathway
    120229394 (RHOA)
   04024 cAMP signaling pathway
    120229394 (RHOA)
   04022 cGMP-PKG signaling pathway
    120229394 (RHOA)
   04150 mTOR signaling pathway
    120229394 (RHOA)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    120229394 (RHOA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    120229394 (RHOA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    120229394 (RHOA)
   04520 Adherens junction
    120229394 (RHOA)
   04530 Tight junction
    120229394 (RHOA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    120229394 (RHOA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    120229394 (RHOA)
   04621 NOD-like receptor signaling pathway
    120229394 (RHOA)
   04625 C-type lectin receptor signaling pathway
    120229394 (RHOA)
   04660 T cell receptor signaling pathway
    120229394 (RHOA)
   04670 Leukocyte transendothelial migration
    120229394 (RHOA)
   04062 Chemokine signaling pathway
    120229394 (RHOA)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    120229394 (RHOA)
   04928 Parathyroid hormone synthesis, secretion and action
    120229394 (RHOA)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    120229394 (RHOA)
  09154 Digestive system
   04972 Pancreatic secretion
    120229394 (RHOA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    120229394 (RHOA)
  09158 Development and regeneration
   04360 Axon guidance
    120229394 (RHOA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    120229394 (RHOA)
   05206 MicroRNAs in cancer
    120229394 (RHOA)
   05205 Proteoglycans in cancer
    120229394 (RHOA)
   05203 Viral carcinogenesis
    120229394 (RHOA)
  09162 Cancer: specific types
   05210 Colorectal cancer
    120229394 (RHOA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    120229394 (RHOA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    120229394 (RHOA)
   05135 Yersinia infection
    120229394 (RHOA)
   05133 Pertussis
    120229394 (RHOA)
   05152 Tuberculosis
    120229394 (RHOA)
   05100 Bacterial invasion of epithelial cells
    120229394 (RHOA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    120229394 (RHOA)
   05418 Fluid shear stress and atherosclerosis
    120229394 (RHOA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hhv04131]
    120229394 (RHOA)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hhv04147]
    120229394 (RHOA)
   04031 GTP-binding proteins [BR:hhv04031]
    120229394 (RHOA)
Membrane trafficking [BR:hhv04131]
 Endocytosis
  Lipid raft mediated endocytosis
   RhoA-dependent endocytosis
    120229394 (RHOA)
Exosome [BR:hhv04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   120229394 (RHOA)
  Exosomal proteins of other body fluids (saliva and urine)
   120229394 (RHOA)
  Exosomal proteins of colorectal cancer cells
   120229394 (RHOA)
  Exosomal proteins of bladder cancer cells
   120229394 (RHOA)
GTP-binding proteins [BR:hhv04031]
 Small (monomeric) G-proteins
  Rho Family
   RhoA/B/C [OT]
    120229394 (RHOA)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU Gtr1_RagA SRPRB VASP_tetra
Other DBs
NCBI-GeneID: 120229394
NCBI-ProteinID: XP_039084323
LinkDB
Position
Unknown
AA seq 193 aa
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
ARRGKKKSGCLVL
NT seq 582 nt   +upstreamnt  +downstreamnt
atggctgccatcaggaagaaactggtgattgttggtgatggagcctgtggcaagacttgc
ttgctcatcgtctttagcaaggaccagttcccagaggtgtatgtacccacagtgtttgag
aactatgtggcagatattgaagttgatggaaagcaggtagagttggctttgtgggataca
gctgggcaggaagattatgatcgcttgaggcctctctcctatccggacactgatgttata
ctgatgtgtttctccatcgacagccctgatagtttagaaaacatcccagaaaaatggact
ccggaagtcaagcacttctgccccaatgtgcccatcatcctggttgggaacaagaaggat
cttcggaatgatgagcacacaaggcgggagctggccaagatgaagcaggagccagtgaaa
ccggaagaaggcagagatatggcgaacaggattggtgcttttgggtacatggagtgttca
gcaaagaccaaagatggagtgagggaggtttttgaaatggccacgagagctgctctgcaa
gccagacgtgggaagaaaaaatctgggtgccttgtcttgtga

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