Hyaena hyaena (striped hyena): 120230153
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Entry
120230153 CDS
T07257
Symbol
ABL1
Name
(RefSeq) tyrosine-protein kinase ABL1 isoform X1
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv04012
ErbB signaling pathway
hhv04014
Ras signaling pathway
hhv04110
Cell cycle
hhv04360
Axon guidance
hhv04722
Neurotrophin signaling pathway
hhv05200
Pathways in cancer
hhv05206
MicroRNAs in cancer
hhv05208
Chemical carcinogenesis - reactive oxygen species
hhv05220
Chronic myeloid leukemia
hhv05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
120230153 (ABL1)
04014 Ras signaling pathway
120230153 (ABL1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
120230153 (ABL1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
120230153 (ABL1)
09158 Development and regeneration
04360 Axon guidance
120230153 (ABL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
120230153 (ABL1)
05206 MicroRNAs in cancer
120230153 (ABL1)
05208 Chemical carcinogenesis - reactive oxygen species
120230153 (ABL1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
120230153 (ABL1)
09166 Cardiovascular disease
05416 Viral myocarditis
120230153 (ABL1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hhv01001
]
120230153 (ABL1)
Enzymes [BR:
hhv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
120230153 (ABL1)
Protein kinases [BR:
hhv01001
]
Non-receptor tyrosine kinases
ABL family
120230153 (ABL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
Kinase-like
SH3_6
ABC1
Motif
Other DBs
NCBI-GeneID:
120230153
NCBI-ProteinID:
XP_039085554
LinkDB
All DBs
Position
Unknown
AA seq
1152 aa
AA seq
DB search
MGQQPGKVLGDQRRPSLPALHFIKGAGKKESSRHGGPHCNVFVEHEALQRPVASDFEPQG
LSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCE
AQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQR
SISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRN
KPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE
EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLL
YMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF
PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERP
EGCPEKVYELMRACWQWTPSDRPSFAEIHQAFETMFQESSISDEVEKELGKKGVRGAAGT
LLQAPELPTKTRTSRRAAEHREPADAAEAPHSRGPGETDPLDHEPPVSPLLPRKERGPQD
GGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERKGPGEDEGRES
SNGAPALAPSDAAEPAKAPKPGGGAGIPNGAFRESGGAGFRSPHLWKKSSTLTSSRLAAG
EEEGGCGSGKRFLRSCSASCVPHGARDTEWRSVTLPRDLQSTGRQFDASTFGGRKSEKPA
LPRKRAGESRSDQAARGAVTPPPRLPKKPEEAADEVFRDTGESSPGSSPPSLTPKLLRRQ
GTGAPPAGLPHRDEAAKSSALGTPAAAEPVPPAGRAGPAAAGGTARAPAEEPRARRHKPS
SESPGRDKAKLAKLKPAPPPPPPASVGKAGKPAHSPTQEAASEAGAGGKAKAAAVVADAV
NSDAVKAGPLGEGIKKPGLPSVPKPQSSGKPAGAPAGAAPAPAPSTVPSASSALAGDPPA
STPFIPLISTRVSLRKTRQPPERIASGTITKGVVLDGTEALCLAISRNSEQMASHSAVLE
AGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPASAWSGPAATQDFSKLL
SSVKEISDIVQR
NT seq
3459 nt
NT seq
+upstream
nt +downstream
nt
atggggcagcagcctggaaaagttcttggggaccagagaaggccgagtttgcctgccctg
cactttatcaaaggagcagggaagaaggagtcatcgaggcacgggggtccacactgcaat
gtttttgtggagcatgaagcccttcagaggccagtagcatctgactttgagccccagggt
ctgagcgaagcagctcgttggaactccaaggaaaaccttctcgctggtcccagtgaaaat
gaccccaacctttttgttgcgctgtatgattttgtggccagtggggacaataccctaagc
atcactaaaggtgaaaagctccgggttttaggctacaatcacaacggggagtggtgtgaa
gcccagaccaaaaatggccagggctgggtgcccagcaactacatcacgccggtcaacagc
ctggagaagcactcctggtaccacgggcccgtgtcccgcaatgccgccgagtacctgctg
agcagcgggatcaacggcagcttcttggtgcgggagagcgagagcagccccggccagagg
tccatctcgctgcgatacgaggggagggtgtatcactaccggatcaacactgcttccgat
ggcaagctctacgtctcctcggagagtcgcttcaacactttagcggagctggttcaccat
cactcgactgtggcggacgggctcatcaccactctccattacccggcccccaagcgcaac
aagcccacggtctacggcgtgtcccccaactacgacaagtgggagatggagcgcacggac
atcaccatgaagcacaagctgggaggaggccagtacggggaggtgtacgagggcgtctgg
aagaagtatagcctcacggtggccgtgaagaccttgaaggaggacaccatggaggtggag
gagttcttgaaggaagctgcagtgatgaaggagatcaagcaccctaacctcgtgcagttg
ctcggggtgtgcacccgggagcccccgttctatataatcactgagttcatgacctatggg
aacctgttggattacctgagggaatgtaaccggcaggaggtgaacgctgtggtgctgctg
tacatggccacgcagatctcgtcagccatggagtacctggagaagaaaaacttcatccac
agagacctcgctgcccggaactgcctagtaggggagaaccacttggtgaaggtggctgat
ttcggcctgagcaggttaatgacgggggacacgtacacagcccacgccggggccaagttc
cccatcaagtggacggcgccggagagcctggcctacaacaagttctccatcaagtctgac
gtctgggcttttggagtattgctttgggaaatcgctacctacggcatgtccccttaccca
ggaatcgacctgtcccaggtgtacgagctgctagagaaagactatcgcatggagcgcccg
gaaggctgcccagagaaggtctacgaactcatgcgagcgtgttggcagtggacgccctcc
gaccggccctcctttgctgaaatccaccaggcctttgagaccatgttccaagagtccagc
atctcggatgaggtggaaaaggagctggggaagaaaggcgtgcgaggggccgcagggact
ttgctgcaggccccagagctgcccaccaagacgaggacgtccaggagagccgcggagcac
agagagcccgccgacgcggccgaggcgccccactccaggggcccgggagagaccgatcct
ctggaccacgagccgcctgtgtccccgctgctccctcggaaagaacggggtccccaggac
ggcggcctgaacgaggacgaacgccttctccccaaagacaagaagaccaacttgttcagt
gccttgatcaagaagaagaagaaaacggccccgacgcccccgaaacgcagcagctccttc
cgggagatggacggccagcccgagcgcaaggggcccggcgaggacgagggccgagaaagc
agcaacggggcgccggcgctcgcaccctcggacgcagccgagccagccaaggccccgaag
cccggcggcggggccggcatccccaacggagccttccgggagtcggggggcgcgggcttc
cggtctccccacctgtggaaaaagtccagcacactgaccagcagccgcctggccgccggc
gaggaggagggcggctgcggctccggcaagcgcttcctgaggtcctgctctgcctcctgc
gtcccccacggggccagggacacggagtggaggtccgtcacgctgcctcgggacctgcag
tccacgggcaggcagttcgacgcgtccacgttcgggggccgcaagagcgagaagccggcc
ctgcctcggaagcgggccggcgagagcaggtccgaccaggcggccagaggcgcggtgacg
cccccaccccggctgccaaagaagcccgaggaggcagctgacgaggtcttccgagacacg
ggcgagtccagcccgggctccagccccccgagcctgaccccaaaactcctccgccggcag
ggcacgggggctcctcccgccggccttccccacagggacgaggctgccaagtccagtgcc
ttggggacacctgccgccgccgagccagtgccccccgccggcagagccgggccggctgcg
gccggagggaccgccagagcgcccgccgaggagcccagggcgcggaggcacaagccttcc
tccgagtccccggggagagacaaggcgaaactggccaagctcaaacctgccccgccgccc
ccgccgccggcctccgtggggaaagccgggaagcccgcgcacagcccgacccaggaagcg
gccagtgaggccggcgccggcgggaaggccaaggccgcggctgtggtcgcggatgccgtg
aacagtgacgctgttaaggccggcccgctgggagagggcatcaaaaagcccgggctcccg
tccgtgccaaagccacagtcgtccggcaagcccgcgggggcgccggccggcgcggctccc
gcccccgccccctccacggtgccgtccgcgtcctccgcgctggccggggacccgccagcc
tccacgcccttcatccctctcatatcgacgcgcgtgtctctccggaaaacgcggcagcct
ccggagcggatcgccagcggcaccatcaccaagggcgtggtcctggacggcaccgaggcc
ctgtgcctggccatctccaggaactccgagcagatggccagccacagcgccgtgctggaa
gccggcaaaaacctgtacacgttctgcgtgagctatgtggattccatccagcaaatgagg
aacaaattcgccttccgcgaggccatcaacaaactagagaacaacctccgcgagctgcag
atctgcccggcgtcagcgtggagcggcccggccgccacgcaggacttcagcaaactcctc
agctccgtgaaggagatcagcgacatcgtgcagaggtag
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