Hyaena hyaena (striped hyena): 120230195
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Entry
120230195 CDS
T07257
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
120230195 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
hhv03021
]
120230195 (SETX)
Enzymes [BR:
hhv01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
120230195 (SETX)
5.6.2.5 RNA 5'-3' helicase
120230195 (SETX)
Transcription machinery [BR:
hhv03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
120230195 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
nSTAND3
ResIII
TniB
Helicase_RecD
SLFN-g3_helicase
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
120230195
NCBI-ProteinID:
XP_039085633
LinkDB
All DBs
Position
Unknown
AA seq
2688 aa
AA seq
DB search
MSTCCWCTPGGISTVDFLKRYASRTRASECQTADEDLCYCLECVAEYHKARDELPFLHQV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEAQLFDFPGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLEDPDIYTSSVLEKGKLILLPAHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQADDDSVDPFWPALHCFMVILDRL
GSKVWGQRIDPIEAFQTIINNMSYNREIQNIRNSSVRTKLDPESYSDNMVSCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTTQETHELQTCLKQIIRNIKLKVP
PCSTFVDLAPVCKTPPASYNKEESKQIGKKSKKDLLCLESSSPTFSKEPMKAEAYQMQEN
ISIKASNTIGEDNKQNYVKDLKLEDHLSAESCIKQGSKSLFTDRAQDPVKTSKGKHKSVK
ENRTSRNGPERGGDRVVIVSAHSLTDSGIDSLAKASTSTEDFSFKDDIFGKTLRAKTKPQ
KAEICAKLSHVIKKQHRKSTSVNDAVNLEENLTVATIDSFFSKKDSGGQKGEGFINHLSL
DPNDIPDDKNGERKSQNSLLLKKKQLKSEEFDIFSSRENSRQIQERQADDKDLVSLTEMT
DPCVKKTLPFKNPMTVLESRGKEVSKSTTSQVSSHLRDQPPSLSPQSEALTDSQVDRDLH
DLSLIAQASVIKFPSDSAQNSSQLQRKVKGKRCFTVNPNNAGEACQGQVIIISDSEDDDG
DEGVLGFEKHIKQDKRSIKKEYPEECVSVAGANVEKNLIKEEETKSLWEFEESDSQFFEF
ESPHDVFSVWHDQEPDKNSVQEDEKNSHLTHINDVTNDWGYDTDYVSEEVIKKVAEGIEK
HTEAQSSSSVGEFCETEVKKPKRKRYEKPVAEDPLRPSPSERNEDQSDILNERGLTENDL
KSTELRSSPSSNIQRDSPISRKKSPKLRTYSKPIRRVPHSKTSKKTHSETKKGQNKSSNY
ISCRTTPAIVPPKILRQYPEPTSAVEKLGLKKAPRRAFQLSQRSQGYVAQLRDHGKTVGV
VDTRKKTKLISPQTLSVKNNKKLLTSQDLQSRRQVKHKSKQNRQGSLGSESTGTRRAGRH
SAQNLDTLVPESDSSDRSSKGGAEVRASNTGKRSVKRVSSEPEPVKTKCVSQVADDPCLL
TQSASVVLNGRIPTDEVIASTSADPLGGGDLAGHHVELTTLKERKLESNSDSEDENLFLT
QRDPEDMDLCSQMANGSEKLIEIGQGKDTAPKEESWSGTKCKYKECVETPQNQGEYCSKH
CEAKAEDEDVFRKPGLPLYASKRPSTTKVFSSRSTSRIANLSKSLESTSALPPSLKRKSN
GVPSASKAPQPTSPLSPKPVGELKSLSNVLRPQTPNNSNRQGYKFLFGESKSFSASSAVN
IVLSSQSISDTFVKEVLKWKYEMFVNFDQCGPPTSLCQSISRPVPVRFQDCGDYFNVFFP
LVVLNTFETVAQEWMSSPNKDKFYQLHLRKFPADYKKYWEFVVHLEECELTKQLHPKEND
LVFLVLENGEDTEGNRMPDFNEYYCGYVHKFRRTSVMRNGKSECSLSIQTQDNLMLNLNE
LVKCTVISSLVTTQRKLKAMSLLSGRNQLARVVLNPNPMDFCTKDLLTTTSERIIAYLKD
FNEDQKKAIETAYAMVKHSPSVAKVCLIHGPPGTGKSKTIVGLLYRLLTESQRRGHSDEN
SNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPMGNCGDINLVRLGPEKSIN
NEVLRFSLDSQVNHRMKKDLPSHVQEMHRRKEFLDHQLDELSRQRALCRGGKETQRQELD
EKIAKVSKERQELASKIKEVQGRPQKTQSIIILESHVICCTLSTSGGLLLESAFRGQGGV
PFSCVIVDEAGQSCEVETLTPLIHRCNKLVLVGDPKQLPPTVISMGWNQKRPFSESLLVG
NLTPPKPCHKAQEYGYDQSMMARFYKLLEDNVEQNVIGRLPVLQLTVQYRMHPDICLFPS
NYVYNKSLKTNRLTETNRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKL
IKDKRRDVTFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTC
VRANAMQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIK
TCDKNYRHDAAKILKLKPVLQRSLTQPPTGAPEMAWPQGGLPGSKPDGEFARTSSPSSLY
HVPSDSKESAGTVTAKDPERPPIQDRLRDPRLLRRLGLDPEAKGTCPWDPQPLSPQHPGA
TPPLGEPGFPSSHQDLGGAQPPAARGAALGTHKPPVQREPPAAGTEASASKRTYDWEGGV
SHRRETRAFSEGDQELQSPERRHVRRHSGWDHRRLEGDDGGSKKRRFL
NT seq
8067 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgctgttggtgtacgccaggtggtatttccaccgttgacttcctgaagcgc
tatgcgtccaggacccgcgccagtgaatgtcagacagctgacgaagacctctgttactgc
ctagagtgtgtggccgagtaccacaaagcccgggacgagctgccattcttgcatcaggtt
ttgtgggaattagaaactttacgtctcataaatcattttgaaaaatccatgaaggcagaa
attggagatgatgatgaattgtacatagtagacaacaatggagaggcacaactatttgac
ttccccggccaagactttgaaaataagcttcgagttcctcttcttgaaatcctgaagtat
ccatatctgcttttacatgaacgtgtcaacgaattatgtgtcgaagcactttgtcggatg
gaacaagctaattgctcctttcaggttttcgacaaacatccaggcatttatttgtttctg
gtccatcccaacgaaatggttcgacgttgggctatcctgaccgcaaggaatttgggaaaa
gtggacagagatgactattatgacttgcaggaagttttaacttgcctttttaaagtcatc
gagctgggacttttggaagatccggacatttatacttcctctgtcctcgagaagggtaaa
ctgatccttctacctgcccacatgtacgataccaccaactacaagaactactggttgggt
atttgcatgttgctgaccattcttgaagagcaggccatggactccctgttgctgggctca
gacaaacagaatgatttcatgcagtccatacttcacaccatggagaggcaagcagacgat
gatagcgtggatcctttctggccagcattacactgtttcatggtgattctggatcgcctt
ggatcaaaggtctggggtcaacgcattgatcctattgaggcatttcagaccataatcaac
aatatgagctacaatagagagatccagaatatacggaacagctctgtaaggaccaagtta
gacccggagtcatattcggataatatggtgtcctgcagccagattgtatacaattataat
cctgaaaagaccaaaaaggattctgggtggagatcagccatttgcccagattactgtcct
aacatgtatgaggagatggaaacattagccagcgtgcttcagtcagatattggtcaagac
atgcgtgttcacaacagcacgtttctgtggttcatcccttttgttcagtccctcatggat
cttaaggatttgggtgtggcttatatagtagaggttattcaccatctgcactctgaagtc
aaagatgtcctcaaccaaacagatgctgtgtgcgacaaagttactgagttttttcttcta
attttggtgtccgtgattgagctgcacagaaataaaaaatgtttgcacttgctgtgggtt
agctcccagcagtgggtggaggctgttgtaaaatgcgccaagcttcctaccactgcattt
gcacggagttccgagaagtcgtctggaaattgttccaaaggaacagcaatgatatcatct
ctgtcgttacattcgatgccatctaactctgtccagctggcttgtgtgcagctcattaga
agtctccttaaagaaggttatcagcttgggcagcaaactctgtgcaagcgattctgggat
aagctcaacttatttctgcgtggaaatttgtctctaggttggcaattgactactcaggaa
acccatgagttacaaacttgtttaaagcaaattattaggaacataaaattaaaagtacct
ccatgtagcacttttgtggatctggcccctgtttgtaaaacccctcctgcgtcttataat
aaagaagaaagtaagcagatagggaagaagtctaaaaaagacctgctctgtctggaaagc
tccagcccaacattttctaaagaaccaatgaaagcagaggcatatcaaatgcaagagaat
atatcaatcaaagcaagtaacactataggagaggataataagcaaaattatgtaaaagat
ttgaaattggaagaccatctctcagctgagtcatgcataaagcagggtagtaaaagcctt
ttcactgacagagctcaagacccagttaaaacaagtaaagggaagcataagtctgtgaaa
gagaatcgtacttccagaaatggtcccgaaaggggaggtgacagagtggtgatagtgtca
gcacactcgttgactgattctggcattgactctctagcaaaggcgtccacatcaactgag
gatttctctttcaaggatgatatttttggcaaaaccttgagagcaaaaactaagccacag
aaagccgaaatctgcgctaagttatcacatgtgataaagaagcaacacaggaaaagtact
tcggtcaatgatgctgtcaatttagaggaaaacctaactgtggctaccattgacagtttc
ttttcaaagaaagattcaggaggtcagaaaggggagggcttcataaaccatctctctcta
gaccctaatgacattcccgatgataaaaatggggaacgaaaatctcaaaacagtttattg
ctgaaaaagaaacaattaaagagtgaagagtttgatatcttctcttcccgtgaaaatagc
cgtcaaatacaggaacgtcaggccgatgataaagatttggtctcattgacggaaatgact
gatccttgtgtgaagaaaaccttgcccttcaaaaatcccatgactgttcttgaatcaaga
ggtaaggaagttagcaagagtaccaccagtcaggtgtcttctcacttgagagaccagcct
cccagcctaagtccacagtccgaagccttgacggactcccaggtcgaccgcgacctccac
gacttatctttaatagctcaagccagtgttattaagtttccatcagattcagcccaaaac
tcgtcccagctacaaaggaaagtaaaaggtaaaagatgtttcacagttaacccaaataat
gctggcgaagcctgccagggccaggtgattattatttcagattccgaagatgatgatggc
gatgaaggagttttgggttttgagaaacacatcaaacaagacaaaagaagcatcaagaag
gagtacccggaggagtgtgtttcagtagctggtgcaaatgtggaaaagaatctaataaag
gaagaagagacaaagtccctgtgggagtttgaggaatcggattctcagttttttgagttt
gaaagtccacatgacgtgttttcagtttggcacgatcaggaaccagacaagaattcagtt
caagaggatgaaaaaaattcacatttgactcacataaacgatgtcacaaatgactggggt
tatgatacagattatgtatctgaagaggttattaagaaagtagcagagggcattgaaaaa
cacacagaagcacagagtagtagttctgttggggaattttgcgaaactgaagtaaaaaaa
cctaagagaaaacgatatgaaaaacctgtagctgaagatcctctgaggccttcaccttct
gagagaaacgaggaccagtctgatattcttaatgagagaggtctgactgaaaatgatctt
aaaagtacagagctaaggtctagtcccagttcgaatattcagagagactctccgatttca
cgaaagaaatctccaaagcttcgtacttactccaaacccatcaggagagtcccgcattct
aaaacttctaagaaaacacattcagaaaccaaaaaagggcagaataaaagttcaaattac
ataagttgtaggacaactcctgctatagtcccaccaaagatacttcgccagtaccctgaa
ccaacttcagctgttgagaaactgggtctgaaaaaggctcctcgtagggcgtttcagtta
tctcagcgatctcaagggtatgtagctcagttacgcgaccatggcaaaactgttggagtg
gttgatactagaaaaaagactaaattaatttctcctcagactctctccgtcaaaaataat
aagaagctgttgacaagccaagatcttcagtcacgaaggcaggtgaaacacaaatcgaaa
cagaacaggcaaggatctctgggttctgaaagtacaggtaccagaagagcaggtcggcat
tcggcacagaatcttgacacgcttgtcccagaatctgatagctcagatcgtagttctaaa
ggaggcgctgaggtgcgtgccagcaatactgggaaacgatcagtaaagcgtgtgtcttcc
gaaccagaacccgtgaaaaccaaatgtgtttctcaggtggctgatgatccttgccttttg
acccagagtgcttctgttgtgttaaacggaagaataccaacagatgaagtcattgcctct
acgtcagctgaccctttaggcggaggtgacctagcaggacatcatgtagagttgaccact
ttgaaagagagaaagcttgaatccaacagtgactcggaggatgagaatctatttctaaca
cagcgtgaccctgaagatatggatttatgttcacaaatggcgaacggtagtgagaagctt
attgagataggtcaggggaaagatacagctccgaaggaagaatcttggagtggcacaaag
tgtaagtacaaggaatgtgttgaaaccccacaaaaccagggtgaatactgctcgaaacac
tgtgaagctaaagcagaggatgaagatgtgtttcgtaaaccgggcttgcccctctacgcg
tctaagagaccttccactactaaggtgtttagctcgagaagtacttcacgaattgctaat
ctttccaagtctttggaaagtacctctgcactgccgccgtccctaaaacgtaagtccaac
ggggtgccgtctgcttcgaaagctccacagccaacctctccgttgtctccaaagccagtg
ggtgaactgaagagtttgtccaatgttcttcgtcctcagactccaaataattccaacagg
caaggttacaaatttctgtttggcgaaagcaaatctttttcggcttcctctgcagtaaac
attgtcctgtcctcgcagtccatctctgacacctttgttaaagaggtcttaaagtggaag
tacgaaatgtttgtgaacttcgatcagtgcgggccccccacaagcctttgtcagtccatc
tcaagaccggtgcctgtcagatttcaagactgtggagattactttaatgtttttttccct
ttggtggtattgaatacttttgaaacggtggcgcaggagtggatgagctctccgaacaaa
gacaagttctatcagctgcacttacgaaaatttcctgctgattataaaaaatactgggag
tttgtggttcatcttgaggaatgtgaactaactaaacagctgcatccaaaggaaaatgat
ttggtgtttttggttcttgaaaatggagaggacacagagggaaatcgcatgccggatttc
aacgaatattactgcggttatgttcataaatttcgccgcacttcagtcatgcgtaatggg
aaatctgagtgttccctttccatccagactcaagataatttgatgctcaatttaaacgaa
cttgtgaaatgcactgtcatcagttctctggtaactacacaaaggaagttgaaagccatg
tctttgctgagtggacggaaccaactggccagagttgttctgaatccaaaccccatggac
ttctgtacaaaagatttactaactacaacgtccgagagaatcattgcctacctgaaagat
ttcaatgaagaccagaagaaagcgatagaaactgcatatgccatggtcaaacactcccca
tcagttgccaaggtctgtttgattcatggaccacctggaacaggaaaatcaaaaactatc
gttggccttctgtaccgcctgctgacagagagccagaggagggggcactcagatgagaac
tccaacgccaaaatcaaacagaaccgtgtcctcgtgtgtgcgccttccaacgcggctgtt
gacgaacttatgaaaaaaatcatccttgaatttaaagagaagtgtaaagacaagaagaac
cctatgggaaactgtggagatataaatttagtacgtctgggtccagaaaagtctattaat
aatgaggtcctaagatttagtttggacagccaagttaaccacagaatgaaaaaagactta
ccttctcatgttcaggagatgcatagaagaaaagaatttctagatcatcaactagatgaa
ctttcccgccagcgtgctttatgccgaggtggaaaggaaacacagaggcaagaattagat
gaaaaaattgcaaaagtttcaaaagagaggcaggaactagcttctaaaattaaagaggtt
caaggacgcccacagaaaacacagagcatcatcatcttagagtcccatgtcatctgctgc
acgctgagcacgagcggtggtttattgctcgagtctgcttttcgtgggcaagggggtgtc
cccttcagttgtgtcattgtcgatgaggctgggcagtcctgtgaggttgagacccttact
ccactcatccatcgttgcaacaagctggtcctggtcggagaccctaaacagcttcctccc
acggtcatttccatgggctggaatcagaaacgtcctttctctgaatctttgcttgttggt
aatcttacaccaccgaaaccttgccataaggcacaggaatatggctacgaccagtcaatg
atggctcgtttctacaagctgctggaagacaacgttgagcaaaacgtgattggcaggctg
cctgtcttacagctcactgtgcagtacaggatgcacccagacatatgtctcttcccctct
aattatgtttataacaaaagcttgaaaacaaacagactgactgaaaccaatcggtgttca
tcagactggccgtttcaaccttacctcgtgtttgatgtcggagatggctcagagagacgg
gataatgactcatatataaatgttcaagaaataaaactggtaatggaaataattaaactt
attaaagacaaaagaagggatgttactttccggaacattggcataataacccattacaag
gcccagaagacgatgattcagaaggatttggacaaagagtttgatagaaaagggccagcg
gaagtagataccgtggacgcattccagggccgccagaaagattgtgttattgtcacgtgt
gtcagagcgaatgccatgcaaggctcaattggatttctggcaagtttgcaaagattgaat
gtcaccatcacgcgagccaagtacagcctcttcatcctgggacatttaaggaccttgatg
gaaaaccagcactggaaccagctgattcaggacgcgcagaagcggggcgccattatcaag
acgtgcgacaaaaactacaggcatgacgcagccaagattctgaaactcaagcccgtgctg
cagaggagcctgacgcagcctcccaccggggccccggagatggcctggccccagggcggc
ctgcccggcagcaagccagacggtgagtttgccaggacgtcgtccccttcttccctgtat
cacgtgccctctgacagcaaggagtccgccggcaccgttaccgcaaaggacccggaaaga
cctcctattcaggaccggcttcgggacccacgactgctcaggaggctgggcctagaccct
gaagccaaagggacatgcccgtgggatccacagcccctgagcccccagcaccccggagcc
acccctcccctgggagagccaggcttcccctcgagtcaccaggacctgggcggggcccag
ccacccgctgccagaggggccgcgctgggcacccacaaacctcccgtgcagcgggagcct
ccggctgccggcacggaagcgtctgcgagtaaaaggacctatgactgggaaggaggcgtc
agccacaggagggagaccagggctttcagtgaaggggaccaggagctgcagagccctgag
aggcgtcacgtgaggaggcactctggctgggaccacaggagactggagggagacgacggt
ggttccaagaaaagaaggttcttatag
DBGET
integrated database retrieval system
