Hyaena hyaena (striped hyena): 120230198
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Entry
120230198 CDS
T07257
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv00790
Folate biosynthesis
hhv01100
Metabolic pathways
hhv01240
Biosynthesis of cofactors
hhv01523
Antifolate resistance
hhv04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
120230198 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
120230198 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
120230198 (FPGS)
Enzymes [BR:
hhv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
120230198 (FPGS)
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Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
120230198
NCBI-ProteinID:
XP_039085642
LinkDB
All DBs
Position
Unknown
AA seq
581 aa
AA seq
DB search
MSQTRRHLRPALFLAAVSARVPTTRVAARRGLSAWPAPQEPGMEYQDAVRTLNTLQTNAG
YLEQVKRQRGDPQTQLEAMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGRPISPELFTKHFWHLYHRLEESKDSSSCVSMPAYFR
FLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGISSLGLDHTSILGDTVEKI
AWQKGGIFKRGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLARCWLQQKDHRGLGELKVSRPSLLRQMPLAPVFQPTTHMRHGLRDTE
WLGRTQVLRRGPLTWYLDGAHTASSMQACVRWFCQALHRHPRPGRGPEVRVLLFNSTGDR
DPVTLLKLLQPCQFDYAVFCPNLTEVSTAGNADQQNFMVTLDQVLLRCLAHQEHWSRLEE
EQAGPEPGAPASLLLAPHPPEAHSAASSLVFSCISHALQWISQGRDPVFQPPDPPQGLLA
HAVAGSGADVLREAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1746 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcagacgcgccgccacctgcgccccgctcttttcctggcggcggtttctgcgcgc
gttccaactacccgggtagctgcgcggcgagggctgagcgcgtggcctgcgccgcaggag
cccggcatggagtatcaggatgccgtgcgcacactgaacaccctgcagaccaatgctggc
tacctggagcaggtaaagcgccagcgcggtgaccctcaaacacagctggaagccatgaag
ctgtacttggcacggagtgggctgcaggtggaagacttggaccagctgaacattattcac
gtcactgggaccaaggggaagggttccacttgtgcctttactgaacgtattctccgaagc
tatggcctgaagacaggattctttagctctccccacctggtgcaggtgcgggagcggatc
cgcatcaacgggcggcccataagccctgagctcttcaccaagcacttctggcacctctac
caccggctggaggagagcaaggacagcagcagctgtgtctccatgcccgcctacttccgc
ttcctcacgctcatggccttccatgtcttcctccaagagaaggtagacctggcagtggtg
gaagtgggcattggtggcgcttacgactgcaccaacatcatcaggaagcctgtggtatgt
ggcatctcctctctcggcctcgaccacaccagcattctgggagacacggtggagaagatc
gcctggcagaaagggggcatcttcaagcgtggcgtccccgccttcaccgtgctccagcct
gacggtcccctggcagtgctgagggaccgtgctcagcagatctcatgtcctctctacctg
tgcccaccgctggaagctctggaggaaggggggcctccgctgaccctgggcctggaggga
gagcaccagcggtccaatgccgccttggccttgcagctggctcgctgttggctgcagcag
aaggaccaccggggcctcggggagctgaaggtgtccaggcccagtctcttgcggcagatg
cccctggcacccgtgttccagcccacgacccacatgcggcatgggcttcgggacacggag
tggctgggccggacgcaggtgctgcggcgcgggcccctcacctggtacctggacggcgcg
cacactgccagcagcatgcaggcctgcgtgcgctggttctgccaggcgctacaccgccac
ccgaggccgggccgcgggcctgaggtgcgcgtcctgctttttaactccacgggggaccgg
gatcctgtgaccctgttgaagctgctgcagccctgtcagtttgactatgccgttttctgc
cctaacctgacagaggtctcaactgccggcaatgcagaccagcagaacttcatggtgacc
ttggaccaggtgttgctccgctgcctcgcgcaccaggagcattggagccgcctggaggag
gagcaggccggcccggagcccggagcgcccgcatctctgctgctggctccccacccaccc
gaagcccatagtgccgccagctccctcgtcttcagctgcatctcccatgccctgcagtgg
atcagccaaggccgggaccctgtgtttcagccacccgatcccccacagggtctcctcgcc
catgctgtggcaggcagcggggccgacgtgctccgtgaggctgctgccatccacgtgctg
gtcacaggcagcctgcacctggtgggtggcgtcctgaagctgctggagcccagcctgtcc
cagtag
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