KEGG   Hyaena hyaena (striped hyena): 120231429
Entry
120231429         CDS       T07257                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
hhv  Hyaena hyaena (striped hyena)
Pathway
hhv04010  MAPK signaling pathway
hhv04012  ErbB signaling pathway
hhv04620  Toll-like receptor signaling pathway
hhv04664  Fc epsilon RI signaling pathway
hhv04668  TNF signaling pathway
hhv04912  GnRH signaling pathway
hhv04926  Relaxin signaling pathway
hhv04935  Growth hormone synthesis, secretion and action
hhv04936  Alcoholic liver disease
hhv05132  Salmonella infection
hhv05135  Yersinia infection
hhv05142  Chagas disease
hhv05161  Hepatitis B
hhv05166  Human T-cell leukemia virus 1 infection
hhv05167  Kaposi sarcoma-associated herpesvirus infection
hhv05169  Epstein-Barr virus infection
hhv05208  Chemical carcinogenesis - reactive oxygen species
hhv05417  Lipid and atherosclerosis
hhv05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hhv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120231429 (MAP2K4)
   04012 ErbB signaling pathway
    120231429 (MAP2K4)
   04668 TNF signaling pathway
    120231429 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    120231429 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    120231429 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    120231429 (MAP2K4)
   04926 Relaxin signaling pathway
    120231429 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    120231429 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    120231429 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    120231429 (MAP2K4)
   05161 Hepatitis B
    120231429 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    120231429 (MAP2K4)
   05169 Epstein-Barr virus infection
    120231429 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    120231429 (MAP2K4)
   05135 Yersinia infection
    120231429 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    120231429 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    120231429 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    120231429 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    120231429 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hhv01001]
    120231429 (MAP2K4)
Enzymes [BR:hhv01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     120231429 (MAP2K4)
Protein kinases [BR:hhv01001]
 Serine/threonine kinases: STE group
  STE7 family
   120231429 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Seadorna_VP7 Pkinase_fungal ABC1 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 120231429
NCBI-ProteinID: XP_039087514
LinkDB
Position
Unknown
AA seq 400 aa
MAAPSPSGGGGGSGGGSGSGTPGPVGPPAPGHPAVSSMQGKRKALKLNFANPPFKSTARF
TLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKM
VHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICME
LMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDR
SGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYE
LATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYK
ELLKHPFILMYEERTVEVACYVCKILDQMPATPSSPMYVD
NT seq 1203 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggcggctccgggggcggcagcggcagcggc
accccgggccccgtggggcccccggcgccgggccacccggccgtcagcagcatgcagggt
aaacgcaaagcactgaagttgaattttgcaaatccacctttcaaatctacagcaaggttt
actctgaatcccaatcctacaggagttcaaaacccacacatagagagactgagaacacac
agcatcgagtcatcggggaaactgaagatctcccctgagcagcactgggatttcaccgcg
gaggacttgaaagacctcggagagattggacgaggagcatacggttctgtcaacaaaatg
gtccacaaaccaagtgggcaaataatggcagttaaaagaattcggtcaacagtggatgaa
aaagaacaaaaacaacttctaatggatttggatgtagtaatgcgcagtagtgattgcccg
tacattgttcagttttatggtgcactcttcagagagggtgactgttggatctgtatggaa
ctcatgtctacctcgtttgataagttttacaaatatgtatatagtgtattagatgatgtt
attccagaagaaattttaggcaaaatcactttagcaactgtgaaagcactaaaccactta
aaagaaaacttgaaaatcattcacagagatatcaaaccttccaatattcttctggacagg
agtggaaatattaagctctgtgactttggcatcagtggacagctggtggactccattgcc
aagacaagagatgccgggtgtaggccatacatggcacctgagagaatagacccgagcgca
tctcgacaaggatatgatgtccgctctgatgtctggagtttggggatcacattgtacgag
ttagccacaggccgatttccgtatccaaagtggaatagtgtattcgatcaactaacacaa
gtcgtgaaaggagaccctccccagctgagcaactcggaggaaagggagttctcccccagt
ttcatcaactttgtcaacttgtgccttacgaaggatgaatccaaaaggccaaagtataaa
gaacttctgaaacatccctttattttgatgtatgaagaacgcaccgtagaggtcgcatgc
tatgtttgtaaaatcctggatcaaatgccagccactcccagctcccccatgtacgtcgac
tga

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