Hyaena hyaena (striped hyena): 120232428
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Entry
120232428 CDS
T07257
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC isoform X1
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv00230
Purine metabolism
hhv00670
One carbon pool by folate
hhv01100
Metabolic pathways
hhv01523
Antifolate resistance
Module
hhv_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
120232428 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
120232428 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
120232428 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hhv04147
]
120232428 (ATIC)
Enzymes [BR:
hhv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
120232428 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
120232428 (ATIC)
Exosome [BR:
hhv04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
120232428 (ATIC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-GeneID:
120232428
NCBI-ProteinID:
XP_039089074
LinkDB
All DBs
Position
Unknown
AA seq
592 aa
AA seq
DB search
MAPSQLALFSVSDKTGLVEFARNLTSVGLNLIASGGTAKTLRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVVCNLYPFVKTVASPDVTVEQA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVAVAAEMQNSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQVYTLKPKLPITVLNGAPGFINL
CDALNAWQLVQELKEALDLPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
TAYARARGADRMSSFGDFIALSDICDVPTAKIISREVSDGIIAPGYEDEALKILSKKKNG
SYCVLQMDQSYSPDENEVRTLFGLRLSQKRNNGVIDRSLFSNVVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKADCWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVSGTIGEDEDLVKWKALFEDVPALLTEAEKKEWIDKLNEVSISSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADRVVVEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccagccagctcgccttatttagtgtctctgacaaaacgggcctcgtggaattt
gccagaaacttaacttctgttggtttgaatctgatcgcttctggagggactgcaaaaacc
ctcagggatgcaggtctggcggtcagagatgtctctgagttaacgggatttcctgaaatg
ttagggggacgtgtgaaaaccttgcatcctgcagtccacgctggaatcttggctcgtaat
atcccagaagataatgctgacatggcaagacttgattttaatcttatcagggttgtcgtc
tgtaatctgtatccctttgtgaagacagtggcttctcccgatgtaactgttgaacaggct
gttgagcagattgatattggtggagtaaccctactgagagcagcagccaaaaaccatgct
cgagtaacagtagtatgtgaacccgaggactatgtggccgtggccgcagagatgcagaac
tccgacagtaaagacacctccttggagactagacgccagttagctttgaaggctttcact
catacggcacaatatgatgaagcaatttcagattacttcaggaaacagtatagtaaagga
atatctcagatgcccttgaggtatggaatgaatcctcaccaaactcctgctcaggtatac
acgctgaagcccaagcttcccatcacagttctaaatggagcccctggatttataaatttg
tgtgatgctttgaatgcctggcagctggtgcaggagctcaaagaagctttagaccttcct
gccgctgcctctttcaaacatgtcagcccagcaggtgctgctgttggaattccactaagt
gaagatgaggccaaagtctgcatggtctatgatctgtataaaaccttgacgcccatatca
actgcgtatgcaagagcaagaggggctgataggatgtcttcatttggtgactttattgca
ttatctgatatttgtgatgtccctactgccaaaattatctccagagaggtatctgatggt
atcattgccccaggatatgaagatgaagctttgaaaatactttctaaaaagaaaaatggg
agctactgtgttcttcagatggaccagtcttacagtccagatgaaaatgaagttcgaact
ctctttggtcttcgcttaagtcagaagagaaataatggtgtcatcgacaggtcattattt
agcaatgttgtgaccaagaataaagatttgccagagtctgcactcagagacctcatcgta
gccaccattgctgtgaagtacacgcagtctaactctgtgtgttatgccaagaatggtcag
gttattggcattggagcaggacagcagtcgcgaatacattgcacacgccttgctggggat
aaggcagactgttggtggcttagacatcatccgcaagtgctttcaatgaagtttaaaact
ggagtgaagagagcagaaatctccaatgccattgatcagtatgtttctgggaccattggc
gaggatgaagatttggtaaagtggaaggcattatttgaggatgtgcctgcactattaact
gaagcagagaagaaggagtggattgacaaacttaatgaagtttctatcagctctgatgct
ttctttcctttcagggataacgtagacagagctaaaaggagcggcgtggcgtacattgct
gctccttctggttctgctgccgacagagttgtggtagaggcttgcgatgaactggggata
attctcgctcatacgaatcttcggctctttcatcattga
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