Hyaena hyaena (striped hyena): 120233505
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Entry
120233505 CDS
T07257
Symbol
GNE
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv00520
Amino sugar and nucleotide sugar metabolism
hhv00541
Biosynthesis of various nucleotide sugars
hhv01100
Metabolic pathways
hhv01250
Biosynthesis of nucleotide sugars
Module
hhv_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
120233505 (GNE)
00541 Biosynthesis of various nucleotide sugars
120233505 (GNE)
Enzymes [BR:
hhv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
120233505 (GNE)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
120233505 (GNE)
BRITE hierarchy
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Paralog
GFIT
Motif
Pfam:
Epimerase_2
ROK
Hexokinase_1
FGGY_N
DRTGG
Glucokinase
Motif
Other DBs
NCBI-GeneID:
120233505
NCBI-ProteinID:
XP_039090716
LinkDB
All DBs
Position
Unknown
AA seq
753 aa
AA seq
DB search
MEINVYPHWKLCFQGPHELYFKNLSKQKKQVMEKNGNNRKLRVCVATCNRADYSKLAPIM
FGIKMEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVG
LALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHA
ITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDV
KSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKG
IEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGE
NVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCF
PPVKDNISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLI
LQMCVEAAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLH
LPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGH
LVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGAVHLIQ
AAKLGNVKAQNILRTAGTALGLGVVNILHTINPSLVILSGVLASHYIHIVKDVIRQQALS
SVQDVDVVVSDLVDPALLGAASMVLDYTTRRIC
NT seq
2262 nt
NT seq
+upstream
nt +downstream
nt
atggaaatcaatgtgtatccccactggaagttatgttttcaaggacctcatgaactctat
tttaagaacctctcaaaacaaaagaaacaagttatggaaaagaatgggaataaccgaaag
cttcgggtttgtgttgcgacttgcaaccgtgctgattattcgaaacttgctccgatcatg
tttggcattaaaatggaacctgagttctttgaacttgatgtggtggtacttggttctcac
ctgatagatgattatgggaatacatatcgcatgattgaacaagatgactttgacattaac
accaggctacacacgattgttaggggggaagatgaggcagccatggtggagtcagtaggc
ttggccctagtgaagctaccagatgtccttaatcgtttgaagcctgatatcatgattgtt
catggagacagatttgatgccctggctttggctacatctgccgccttgatgaatatccga
atccttcatattgaaggtggggaagtcagtgggaccattgatgattccatcagacatgcg
ataacaaaactggctcattatcacgtgtgctgcacccgaagtgcagagcagcacctgata
tccatgtgtgaggaccatgatcgcatccttctggcaggctgcccttcctatgacaaactt
ctctctgccaagaacaaagactacatgagcatcattcggatgtggttaggtgatgatgta
aagtctaaagattacattgttgcactacagcaccccgtgaccactgacattaagcattcc
ataaaaatgtttgaattaacattggatgcgcttatctcatttaacaagcggaccctagtt
ctgtttccaaacattgatgcaggaagcaaagagatggttcgagtgatgcgaaagaagggc
atcgagcatcatcccaatttccgtgcagttaaacacgtcccatttgaccagtttatacag
ttggttgcccatgctggttgtatgattggaaacagcagctgtggagtacgagaggttgga
gcttttggaactcctgtgattaatctaggaacacgtcagattggaagagaaactggggag
aatgtccttcatgtccgggatgctgatacccaagacaaaatactgcaagcactgcatctt
cagtttgggaaacagtacccgtgttcaaagatatatggagatggaaatgctgttccaagg
attttgaagtttctcaaatctatcgatcttcaggagccactgcaaaagaaattctgcttt
cctcctgtaaaggacaacatctctcaagatattgaccatattcttgaaactctaagtgcc
ttggctgttgatctcggtgggacaaacctccgagttgcaatagtcagcatgaagggtgaa
attgtcaagaagtatactcagttcaatcctaaaacctatgaagagaggattaatttaatc
ctacagatgtgtgttgaagctgcagcagaagctgtaaaactgaactgcagaattttggga
gtaggtatttccacgggtggccgtgtaaatcctcgggaaggaattgtgctgcattcaact
aaactgattcaagaatggaactctgtggacctcaggacccccctctctgacaccttacat
ctgcccgtgtgggtggacaatgatggcaattgtgctgccctggcagaaaggaaatttggc
caaggaaagggcctggaaaacttcgtgacacttatcacaggcacaggaattggcggtggc
atcatccatcagcacgaattgatccatggaagctccttctgtgctgcagaacttggccac
cttgtcgtgtctctggatgggcccgattgttcctgtggcagtcacgggtgtattgaagca
tatgcctctggaatggccttgcagagggaagcaaaaaagctacatgatgaagacctgctc
ttggtggaagggatgtccgtgccgaaagacgaggccgtgggtgcagtccatctcatccaa
gctgcaaaactcggcaacgtgaaggcccagaacatcctgagaacagctggaacggctttg
ggtcttggggttgtgaacatcctccacaccatcaacccttctcttgtgatcctctctgga
gtcctagccagtcactacatccacatcgtcaaagatgtcatccgccaacaagccttgtcc
tcggttcaggatgtggacgtggtagtttcggatttggtggaccccgccctgctcggtgcc
gccagcatggttttggactacacaactcgcaggatctgctag
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