Hyaena hyaena (striped hyena): 120233674
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Entry
120233674 CDS
T07257
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv01521
EGFR tyrosine kinase inhibitor resistance
hhv01522
Endocrine resistance
hhv04010
MAPK signaling pathway
hhv04014
Ras signaling pathway
hhv04015
Rap1 signaling pathway
hhv04066
HIF-1 signaling pathway
hhv04068
FoxO signaling pathway
hhv04081
Hormone signaling
hhv04114
Oocyte meiosis
hhv04140
Autophagy - animal
hhv04144
Endocytosis
hhv04150
mTOR signaling pathway
hhv04151
PI3K-Akt signaling pathway
hhv04152
AMPK signaling pathway
hhv04211
Longevity regulating pathway
hhv04213
Longevity regulating pathway - multiple species
hhv04510
Focal adhesion
hhv04520
Adherens junction
hhv04550
Signaling pathways regulating pluripotency of stem cells
hhv04730
Long-term depression
hhv04913
Ovarian steroidogenesis
hhv04914
Progesterone-mediated oocyte maturation
hhv05200
Pathways in cancer
hhv05202
Transcriptional misregulation in cancer
hhv05205
Proteoglycans in cancer
hhv05214
Glioma
hhv05215
Prostate cancer
hhv05218
Melanoma
hhv05224
Breast cancer
hhv05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
120233674 (IGF1R)
04014 Ras signaling pathway
120233674 (IGF1R)
04015 Rap1 signaling pathway
120233674 (IGF1R)
04066 HIF-1 signaling pathway
120233674 (IGF1R)
04068 FoxO signaling pathway
120233674 (IGF1R)
04151 PI3K-Akt signaling pathway
120233674 (IGF1R)
04152 AMPK signaling pathway
120233674 (IGF1R)
04150 mTOR signaling pathway
120233674 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
120233674 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
120233674 (IGF1R)
04140 Autophagy - animal
120233674 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
120233674 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
120233674 (IGF1R)
04520 Adherens junction
120233674 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
120233674 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
120233674 (IGF1R)
04914 Progesterone-mediated oocyte maturation
120233674 (IGF1R)
09156 Nervous system
04730 Long-term depression
120233674 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
120233674 (IGF1R)
04213 Longevity regulating pathway - multiple species
120233674 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
120233674 (IGF1R)
05202 Transcriptional misregulation in cancer
120233674 (IGF1R)
05205 Proteoglycans in cancer
120233674 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
120233674 (IGF1R)
05214 Glioma
120233674 (IGF1R)
05218 Melanoma
120233674 (IGF1R)
05215 Prostate cancer
120233674 (IGF1R)
05224 Breast cancer
120233674 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
120233674 (IGF1R)
01522 Endocrine resistance
120233674 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hhv01001
]
120233674 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hhv04090
]
120233674 (IGF1R)
Enzymes [BR:
hhv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
120233674 (IGF1R)
Protein kinases [BR:
hhv01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
120233674 (IGF1R)
CD molecules [BR:
hhv04090
]
Proteins
120233674 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
120233674
NCBI-ProteinID:
XP_039090971
LinkDB
All DBs
Position
Unknown
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTDSNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWGHRNLTIKSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTGKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDAEPGILLQGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVTQVTNTTMSSRNRNATVADTYNVTDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
ESRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGARLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPEDMESIPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gccgcgctctccctctggccgacgagtggagaaatctgcgggccgggcatcgatatccgt
aacgactatcagcagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacttgctgctgttccgcgtggccggccttgagagcctcggggacctcttc
ccgaacctcacggtcatccgtggctggaaactcttttacaactacgccctggtcatcttt
gagatgaccaacctcaaggatattgggctttacaatctgaggaacattacccggggggcc
atcaggattgagaaaaatgccgacctctgttacctctccacggtggactggtccctgatc
ctggatgcagtgtccaacaactacatcgtggggaacaagcccccaaaggagtgcggggac
ctgtgtccggggacgatggaggagaagccgttgtgcgagaagactaccatcaacaatgag
tacaactaccgctgctggaccacaaaccgctgccagaaaatgtgcccgagcgcgtgcggg
aagcgggcctgcacggacagcaacgagtgctgtcaccccgagtgcctgggcagctgcagc
gcgcccgacaacgacacggcctgcgtggcctgcaggcattactactacgccggcgtctgc
gtgcccacctgcccgcccaacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccagcgccgagagcagcgactccgaggggttcgtgatccacgat
ggcgagtgcatgcaggagtgcccctcggggttcatccggaacgggagtcagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgtgaggaggagaagaaaacaaagacc
attgattctgttacctctgctcaaatgctccaaggatgcaccatcttcaagggcaacttg
ctcattaatatccgccgaggcaataacattgcctcggagctggagaacttcatggggctc
atcgaggtggtgacaggctacgtgaagatccgccattcccacgccttggtctccttgtcc
ttcctaaaaaaccttcgccagatcttaggagaggagcagctggaggggaactactctttc
tatgtcctcgacaaccagaacctgcagcagctctgggactggggccaccgcaacctgacc
atcaaatccgggaagatgtactttgctttcaatcccaagttgtgcgtctccgaaatttac
cgcatggaggaagtgaccgggacgaaggggcgccagagcaaaggggacatcaataccagg
aacaacggagagcgagcctcctgtgaaagtgacgtcctgcacttcacctctacgactacg
gggaagaaccgcatcatcataacctggcaccggtaccggcccccggactaccgggacctc
atcagcttcaccgtctactacaaggaggcaccttttaaaaacgtcacagagtatgatggc
caggatgcctgtggctccaacagctggaacatggtggacgtggacctccctcccaacaag
gacgccgagcctggcattctgctgcagggtctgaagccctggacgcagtatgctgtctac
gtcaaggcagtgaccctcaccatggtagagaatgaccacatccgcggggccaagagtgaa
atcttgtacattcgcaccaatgcttcagttccttccattcccctggatgttctttcggca
tcgaactcttcttctcagctcatcgtgaagtggaacccgccgtcgctgcccaatggcaac
ctaagttactacatcgtgaggtggcagcggcagcctcaggacagctacctttaccggcac
aactactgctccaaagacaaaatccccatcaggaagtatgccgatggcaccattgacatc
gaggaggtgaccgagaaccccaagaccgaagtgtgcggcggagagaaggggccttgctgc
gcctgccccaaaaccgaggccgagaagcaggccgagaaggaggaggctgagtaccgcaaa
gtctttgagaacttcctgcacaactccatctttgtgcccagacctgaaaggaagcggaga
gatgtcacgcaggtcaccaacaccaccatgtccagccggaacaggaacgccacggtggcc
gacacctataatgtcacagacccggaggagctcgagacagaataccctttctttgagagc
agagtggacaacaaggagagaaccgtgatctctaacctccggcctttcaccttgtaccgc
attgacatccacagctgtaaccacgaggctgaaaagctgggctgcagcgcctccaacttc
gtctttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccggtgacctgg
gagtcaaggcctgaaaactccatctttttaaagtggccagaacctgagaatcccaatgga
ctgattctcatgtatgagataaaatacggatcacaaattgaggaccagcgggaatgtgtg
tccagacaggagtaccggaagtacggcggcgccaggctgaaccggctcaacccagggaac
tacacggcccggatccaggccacctctctctctgggaacgggtcgtggacggatcccgtg
ttcttctacgtccctgccaagataacatatgaaaatttcatccacctgatcatcgccctg
cccgtcgccgtcctgttgatagtggggggactggtcatcatgttgtacgtcttccacaga
aaaagaaataatagcaggctggggaatggagtgctgtacgcatccgtgaacccagagtac
ttcagcgccgcagatgtgtacgtacctgatgagtgggaggttgctcgggagaagatcacc
atgagccgagagctggggcagggctcgttcgggatggtctacgagggagttgccaaaggc
gtggttaaagacgagcccgaaaccagggtggccatcaagacggtgaatgaggccgcgagc
atgcgtgaacggattgagtttctcaacgaggcttcagtgatgaaggagttcaattgtcac
catgtggtacgcttgctgggcgtggtgtcccagggccagccgacgctggtcatcatggag
ctgatgacacggggtgatctcaaaagttatctcaggtctctaaggccagaaatagagaat
aatccagtcctagcacctccgagcctgagcaagatgatccagatggcgggagagattgca
gacggcatggcatacctcaacgccaacaagtttgtccacagggaccttgctgcccggaac
tgcatggtggctgaagatttcacggtcaaaattggagatttcggtatgacgagagatatc
tacgagacagactattaccggaaaggaggcaaggggctgctgcctgtgcgctggatgtcg
cccgagtccctcaaggatggggtcttcaccactcactctgacgtctggtccttcggggtc
gttctctgggagatcgccacgctggccgagcagccgtaccagggcttgtccaacgagcaa
gtcctgcgcttcgtcatggagggcggccttctggacaagccggataactgccccgacatg
ctgtttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaggacgagatggagcccggcttccgggaggtgtccttctac
tacagcgaggagaacaagccgcccgagccggaggagctggacctggagccggaggacatg
gagagcatccccctggacccctccgcctcctcgtcctccctgccgctgcccgacagacac
tcaggacacaaggccgagaacggcccgggccccggcgtgctggtgctccgcgccagcttc
gacgagagacagccttacgcgcacatgaacgggggacgcaagaacgagagggccttgcct
ctgccccagtcttcgacctgctga
DBGET
integrated database retrieval system
