KEGG   Hyaena hyaena (striped hyena): 120233735
Entry
120233735         CDS       T07257                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
hhv  Hyaena hyaena (striped hyena)
Pathway
hhv04010  MAPK signaling pathway
hhv04020  Calcium signaling pathway
hhv04022  cGMP-PKG signaling pathway
hhv04114  Oocyte meiosis
hhv04218  Cellular senescence
hhv04310  Wnt signaling pathway
hhv04360  Axon guidance
hhv04370  VEGF signaling pathway
hhv04380  Osteoclast differentiation
hhv04625  C-type lectin receptor signaling pathway
hhv04650  Natural killer cell mediated cytotoxicity
hhv04658  Th1 and Th2 cell differentiation
hhv04659  Th17 cell differentiation
hhv04660  T cell receptor signaling pathway
hhv04662  B cell receptor signaling pathway
hhv04720  Long-term potentiation
hhv04724  Glutamatergic synapse
hhv04728  Dopaminergic synapse
hhv04921  Oxytocin signaling pathway
hhv04922  Glucagon signaling pathway
hhv04924  Renin secretion
hhv05010  Alzheimer disease
hhv05014  Amyotrophic lateral sclerosis
hhv05020  Prion disease
hhv05022  Pathways of neurodegeneration - multiple diseases
hhv05031  Amphetamine addiction
hhv05152  Tuberculosis
hhv05163  Human cytomegalovirus infection
hhv05166  Human T-cell leukemia virus 1 infection
hhv05167  Kaposi sarcoma-associated herpesvirus infection
hhv05170  Human immunodeficiency virus 1 infection
hhv05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hhv05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hhv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120233735 (PPP3CB)
   04310 Wnt signaling pathway
    120233735 (PPP3CB)
   04370 VEGF signaling pathway
    120233735 (PPP3CB)
   04020 Calcium signaling pathway
    120233735 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    120233735 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    120233735 (PPP3CB)
   04218 Cellular senescence
    120233735 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    120233735 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    120233735 (PPP3CB)
   04660 T cell receptor signaling pathway
    120233735 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    120233735 (PPP3CB)
   04659 Th17 cell differentiation
    120233735 (PPP3CB)
   04662 B cell receptor signaling pathway
    120233735 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    120233735 (PPP3CB)
   04921 Oxytocin signaling pathway
    120233735 (PPP3CB)
   04924 Renin secretion
    120233735 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    120233735 (PPP3CB)
   04728 Dopaminergic synapse
    120233735 (PPP3CB)
   04720 Long-term potentiation
    120233735 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    120233735 (PPP3CB)
   04380 Osteoclast differentiation
    120233735 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    120233735 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    120233735 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    120233735 (PPP3CB)
   05163 Human cytomegalovirus infection
    120233735 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    120233735 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    120233735 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    120233735 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    120233735 (PPP3CB)
   05020 Prion disease
    120233735 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    120233735 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    120233735 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    120233735 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hhv01009]
    120233735 (PPP3CB)
Enzymes [BR:hhv01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     120233735 (PPP3CB)
Protein phosphatases and associated proteins [BR:hhv01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     120233735 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 120233735
NCBI-ProteinID: XP_039091102
LinkDB
Position
Unknown
AA seq 525 aa
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVF
SVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSF
EEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ
NT seq 1578 nt   +upstreamnt  +downstreamnt
atggccgccccggagccggcccgggctgcaccgcccccacccccgcccccgccgccccct
cccggggctgaccgcgtcgtcaaagctgtaccttttcccccaacacatcgcttgacatct
gaagaagtatttgatttggatgggatacccagggttgatgttttgaagaaccacttagta
aaagaaggtcgggtagatgaagaaattgcacttagaattatcaatgagggtgctgccatc
cttcggagagagaaaaccatgatagaagtagaggctccaattacagtgtgtggtgacatc
catggccaattttttgatctgatgaaactttttgaagtaggaggatcacctgctaataca
cgatacctttttcttggtgattatgtggacagaggttattttagtatagagtgtgtctta
tatttatgggtcctgaagattctttacccaagcacattatttcttctgagaggcaatcat
gaatgcagacaccttactgaatattttacctttaagcaggaatgtaaaattaaatattca
gaaagagtctatgaagcttgtatggaagcttttgatagcctgcctcttgctgcactttta
aatcaacaatttctttgtgttcatggtggactttcaccagaaatacacacactggatgat
attaggagattagatagattcaaagagccacctgcatttggaccaatgtgtgacttgcta
tggtccgatccttctgaagattttggaaacgaaaaatcacaggaacattttagtcacaat
acagttcgaggatgttcttatttttataactatccagcagtgtgtgaatttttgcaaaac
aataatttgttatcgattattagagctcatgaagctcaagatgcaggctatagaatgtac
agaaaaagtcaaactacagggttcccttcattaataacaattttttcggcacctaattac
ttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtgatgaatatt
cgacaatttaactgttctccacatccttactggttgcccaattttatggatgtcttcaca
tggtctttaccctttgttggagaaaaagtgacagaaatgttggtaaatgttctgagtatt
tgctctgatgatgaactgatgactgaaggtgaagaccagtttgatgtaggttcagctgca
gcccggaaagaaatcataagaaacaaaattcgagcaattggcaagatggcaagggtcttc
tctgttctcagggaggagagtgaaagcgtgctgacactcaagggcctgactcccacaggg
atgttgcctagtggagtgttggctggaggacgacagaccctgcaaagtgccacagttgag
gctattgaggctgaaaaagcaatacgaggattctctccaccacatagaatctgcagtttt
gaagaggcaaagggtttggataggatcaatgagagaatgccaccccggaaagatgctgta
cagcaagatggtttcaattctctgaacaccgcacatgccactgagaaccacgggactggc
aaccatagtgcccagtga

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