Hyaena hyaena (striped hyena): 120233932
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Entry
120233932 CDS
T07257
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2 isoform X1
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv01521
EGFR tyrosine kinase inhibitor resistance
hhv01522
Endocrine resistance
hhv04012
ErbB signaling pathway
hhv04066
HIF-1 signaling pathway
hhv04140
Autophagy - animal
hhv04150
mTOR signaling pathway
hhv04151
PI3K-Akt signaling pathway
hhv04152
AMPK signaling pathway
hhv04211
Longevity regulating pathway
hhv04213
Longevity regulating pathway - multiple species
hhv04350
TGF-beta signaling pathway
hhv04371
Apelin signaling pathway
hhv04666
Fc gamma R-mediated phagosome formation
hhv04714
Thermogenesis
hhv04910
Insulin signaling pathway
hhv04931
Insulin resistance
hhv05163
Human cytomegalovirus infection
hhv05165
Human papillomavirus infection
hhv05170
Human immunodeficiency virus 1 infection
hhv05200
Pathways in cancer
hhv05205
Proteoglycans in cancer
hhv05207
Chemical carcinogenesis - receptor activation
hhv05210
Colorectal cancer
hhv05212
Pancreatic cancer
hhv05221
Acute myeloid leukemia
hhv05224
Breast cancer
hhv05225
Hepatocellular carcinoma
hhv05226
Gastric cancer
hhv05231
Choline metabolism in cancer
hhv05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
120233932 (RPS6KB2)
04350 TGF-beta signaling pathway
120233932 (RPS6KB2)
04371 Apelin signaling pathway
120233932 (RPS6KB2)
04066 HIF-1 signaling pathway
120233932 (RPS6KB2)
04151 PI3K-Akt signaling pathway
120233932 (RPS6KB2)
04152 AMPK signaling pathway
120233932 (RPS6KB2)
04150 mTOR signaling pathway
120233932 (RPS6KB2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
120233932 (RPS6KB2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagosome formation
120233932 (RPS6KB2)
09152 Endocrine system
04910 Insulin signaling pathway
120233932 (RPS6KB2)
09149 Aging
04211 Longevity regulating pathway
120233932 (RPS6KB2)
04213 Longevity regulating pathway - multiple species
120233932 (RPS6KB2)
09159 Environmental adaptation
04714 Thermogenesis
120233932 (RPS6KB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
120233932 (RPS6KB2)
05205 Proteoglycans in cancer
120233932 (RPS6KB2)
05207 Chemical carcinogenesis - receptor activation
120233932 (RPS6KB2)
05231 Choline metabolism in cancer
120233932 (RPS6KB2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
120233932 (RPS6KB2)
09162 Cancer: specific types
05210 Colorectal cancer
120233932 (RPS6KB2)
05212 Pancreatic cancer
120233932 (RPS6KB2)
05225 Hepatocellular carcinoma
120233932 (RPS6KB2)
05226 Gastric cancer
120233932 (RPS6KB2)
05221 Acute myeloid leukemia
120233932 (RPS6KB2)
05224 Breast cancer
120233932 (RPS6KB2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
120233932 (RPS6KB2)
05163 Human cytomegalovirus infection
120233932 (RPS6KB2)
05165 Human papillomavirus infection
120233932 (RPS6KB2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
120233932 (RPS6KB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
120233932 (RPS6KB2)
01522 Endocrine resistance
120233932 (RPS6KB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hhv01001
]
120233932 (RPS6KB2)
Enzymes [BR:
hhv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
120233932 (RPS6KB2)
Protein kinases [BR:
hhv01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
120233932 (RPS6KB2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Pkinase_fungal
ABC1
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
120233932
NCBI-ProteinID:
XP_039091436
LinkDB
All DBs
Position
Unknown
AA seq
480 aa
AA seq
DB search
MAAVFDLDLETEEGSEGEPEFSPSDVCPLGELRAAGLEPVGHCEEVELTETSVNLGPERI
GPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNI
LESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLAL
GHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILV
RSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLTLPPYLTPDARDLVKK
FLKRNPSQRIGGGPGDAADVQRHPFFRHIHWDDLLARRVDPPFRPCLQSEEDVSQFDIHF
TRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRTPV
SPLKFSPFEGFRPSPGPVEPSEPPLPPLLPPPPPSSSAPLPIRPPSGTKKSKRGRGRPGR
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atggcggccgtgtttgacctggacctggagacagaggaaggcagcgagggtgagccagag
ttcagcccctcggacgtgtgtccccttggcgagttgagggcagctggcctggagcctgtg
ggacactgtgaggaggtggagctgacggagaccagtgtgaacctgggccctgagcgcatt
gggccccactgctttgagctgctgcgtgtgctgggcaaagggggttacggcaaggtgttc
caggtgcgaaaggtgcagggcaccaacttggggaagatatatgccatgaaagtcctgagg
aaggccaaaattgtgcgtaacgccaaggacacagcacacacgcgagctgaacggaacatt
ctggagtcggtgaagcaccccttcattgtggagctggcctatgccttccagaccggcggc
aaactctacctcatcctcgagtgcctcagtggcggtgagctcttcacgcatctggagcga
gaaggcatcttcctggaagacacagcctgcttctacctggcagagatcacgctggccctg
ggacatctccactcccaaggcatcatctaccgggacctcaagcctgagaacatcatgctc
aacagccagggccacatcaaactgacagacttcggactctgcaaggagtcgatccacgag
ggcgctgtcacccacactttctgtggcaccattgagtacatggcccctgagattctggtg
cgcagtggccacaaccgggcggtggactggtggagcctgggggccctgatgtatgacatg
ctcactggatcgccacccttcaccgcagagaaccggaagaaaaccatggacaagatcatc
aaagggaagctgacgctgcccccctacctcaccccggatgcccgggacctcgtcaaaaag
tttctgaagcggaatcccagccagcggatcgggggtggccccggggacgctgctgatgtg
cagagacaccccttcttccggcacattcactgggacgacctcctggctcgccgcgtggac
cctcctttcaggccctgtctgcagtcagaggaggacgtgagccagtttgacatccacttc
acacggcagacgccggtggacagtcccgatgacacggccctcagcgagagcgccaaccag
gccttcctgggcttcacgtacgtggctccctccgtcctggacagcatcaaggagggcttc
tccttccagcccaagctccgctcccccaggcggctgaacagcagcccccggaccccggtc
agccccctgaaattctcaccctttgaggggttccggcccagccctggcccagtggagccc
tcggagccccccctacctcctctcctgccgccgccgccgccctcgagctctgcacccctc
cccatccgacccccctcagggaccaagaagtccaagaggggccgtgggcgccctgggcgc
tag
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