Hyaena hyaena (striped hyena): 120234190 Help Entry 120234190         CDS       T07257                                  Symbol PRKCA Name (RefSeq) protein kinase C alpha type   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism hhv  Hyaena hyaena (striped hyena) Pathway hhv01521   EGFR tyrosine kinase inhibitor resistance hhv04010   MAPK signaling pathway hhv04012   ErbB signaling pathway hhv04014   Ras signaling pathway hhv04015   Rap1 signaling pathway hhv04020   Calcium signaling pathway hhv04066   HIF-1 signaling pathway hhv04070   Phosphatidylinositol signaling system hhv04071   Sphingolipid signaling pathway hhv04072   Phospholipase D signaling pathway hhv04082   Neuroactive ligand signaling hhv04150   mTOR signaling pathway hhv04151   PI3K-Akt signaling pathway hhv04261   Adrenergic signaling in cardiomyocytes hhv04270   Vascular smooth muscle contraction hhv04310   Wnt signaling pathway hhv04360   Axon guidance hhv04370   VEGF signaling pathway hhv04510   Focal adhesion hhv04540   Gap junction hhv04613   Neutrophil extracellular trap formation hhv04650   Natural killer cell mediated cytotoxicity hhv04664   Fc epsilon RI signaling pathway hhv04666   Fc gamma R-mediated phagocytosis hhv04670   Leukocyte transendothelial migration hhv04713   Circadian entrainment hhv04720   Long-term potentiation hhv04723   Retrograde endocannabinoid signaling hhv04724   Glutamatergic synapse hhv04725   Cholinergic synapse hhv04726   Serotonergic synapse hhv04727   GABAergic synapse hhv04728   Dopaminergic synapse hhv04730   Long-term depression hhv04750   Inflammatory mediator regulation of TRP channels hhv04911   Insulin secretion hhv04912   GnRH signaling pathway hhv04916   Melanogenesis hhv04918   Thyroid hormone synthesis hhv04919   Thyroid hormone signaling pathway hhv04921   Oxytocin signaling pathway hhv04925   Aldosterone synthesis and secretion hhv04926   Relaxin signaling pathway hhv04928   Parathyroid hormone synthesis, secretion and action hhv04929   GnRH secretion hhv04933   AGE-RAGE signaling pathway in diabetic complications hhv04935   Growth hormone synthesis, secretion and action hhv04960   Aldosterone-regulated sodium reabsorption hhv04961   Endocrine and other factor-regulated calcium reabsorption hhv04970   Salivary secretion hhv04971   Gastric acid secretion hhv04972   Pancreatic secretion hhv05017   Spinocerebellar ataxia hhv05022   Pathways of neurodegeneration - multiple diseases hhv05031   Amphetamine addiction hhv05032   Morphine addiction hhv05143   African trypanosomiasis hhv05146   Amoebiasis hhv05161   Hepatitis B hhv05163   Human cytomegalovirus infection hhv05164   Influenza A hhv05170   Human immunodeficiency virus 1 infection hhv05171   Coronavirus disease - COVID-19 hhv05200   Pathways in cancer hhv05205   Proteoglycans in cancer hhv05206   MicroRNAs in cancer hhv05207   Chemical carcinogenesis - receptor activation hhv05214   Glioma hhv05223   Non-small cell lung cancer hhv05225   Hepatocellular carcinoma hhv05231   Choline metabolism in cancer hhv05415   Diabetic cardiomyopathy hhv05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:hhv00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     120234190 (PRKCA)    04012 ErbB signaling pathway     120234190 (PRKCA)    04014 Ras signaling pathway     120234190 (PRKCA)    04015 Rap1 signaling pathway     120234190 (PRKCA)    04310 Wnt signaling pathway     120234190 (PRKCA)    04370 VEGF signaling pathway     120234190 (PRKCA)    04066 HIF-1 signaling pathway     120234190 (PRKCA)    04020 Calcium signaling pathway     120234190 (PRKCA)    04070 Phosphatidylinositol signaling system     120234190 (PRKCA)    04072 Phospholipase D signaling pathway     120234190 (PRKCA)    04071 Sphingolipid signaling pathway     120234190 (PRKCA)    04151 PI3K-Akt signaling pathway     120234190 (PRKCA)    04150 mTOR signaling pathway     120234190 (PRKCA)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     120234190 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     120234190 (PRKCA)    04540 Gap junction     120234190 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     120234190 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     120234190 (PRKCA)    04664 Fc epsilon RI signaling pathway     120234190 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     120234190 (PRKCA)    04670 Leukocyte transendothelial migration     120234190 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     120234190 (PRKCA)    04929 GnRH secretion     120234190 (PRKCA)    04912 GnRH signaling pathway     120234190 (PRKCA)    04921 Oxytocin signaling pathway     120234190 (PRKCA)    04926 Relaxin signaling pathway     120234190 (PRKCA)    04935 Growth hormone synthesis, secretion and action     120234190 (PRKCA)    04918 Thyroid hormone synthesis     120234190 (PRKCA)    04919 Thyroid hormone signaling pathway     120234190 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     120234190 (PRKCA)    04916 Melanogenesis     120234190 (PRKCA)    04925 Aldosterone synthesis and secretion     120234190 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     120234190 (PRKCA)    04270 Vascular smooth muscle contraction     120234190 (PRKCA)   09154 Digestive system    04970 Salivary secretion     120234190 (PRKCA)    04971 Gastric acid secretion     120234190 (PRKCA)    04972 Pancreatic secretion     120234190 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     120234190 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     120234190 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     120234190 (PRKCA)    04727 GABAergic synapse     120234190 (PRKCA)    04725 Cholinergic synapse     120234190 (PRKCA)    04728 Dopaminergic synapse     120234190 (PRKCA)    04726 Serotonergic synapse     120234190 (PRKCA)    04720 Long-term potentiation     120234190 (PRKCA)    04730 Long-term depression     120234190 (PRKCA)    04723 Retrograde endocannabinoid signaling     120234190 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     120234190 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     120234190 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     120234190 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     120234190 (PRKCA)    05206 MicroRNAs in cancer     120234190 (PRKCA)    05205 Proteoglycans in cancer     120234190 (PRKCA)    05207 Chemical carcinogenesis - receptor activation     120234190 (PRKCA)    05231 Choline metabolism in cancer     120234190 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     120234190 (PRKCA)    05214 Glioma     120234190 (PRKCA)    05223 Non-small cell lung cancer     120234190 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     120234190 (PRKCA)    05161 Hepatitis B     120234190 (PRKCA)    05171 Coronavirus disease - COVID-19     120234190 (PRKCA)    05164 Influenza A     120234190 (PRKCA)    05163 Human cytomegalovirus infection     120234190 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     120234190 (PRKCA)    05143 African trypanosomiasis     120234190 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     120234190 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     120234190 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     120234190 (PRKCA)    05032 Morphine addiction     120234190 (PRKCA)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     120234190 (PRKCA)    05415 Diabetic cardiomyopathy     120234190 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     120234190 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     120234190 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hhv01001]     120234190 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hhv04131]     120234190 (PRKCA) Enzymes [BR:hhv01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      120234190 (PRKCA) Protein kinases [BR:hhv01001]  Serine/threonine kinases: AGC group   PKC family [OT]    120234190 (PRKCA) Membrane trafficking [BR:hhv04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     120234190 (PRKCA) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C ABC1 C1_2 DUF4656 Motif Other DBs NCBI-GeneID:  120234190 NCBI-ProteinID:  XP_039091852 LinkDB All DBs Position Unknown AA seq 672 aa AA seqDB search MADVFPANDSTTSQDVANRFARKGALRQKNVHEVKNHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNME LRQKFEKAKLGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRI DWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN PQFVHPILQSAV NT seq 2019 nt NT seq  +upstreamnt  +downstreamnt atggctgacgttttcccggccaacgactccacgacgtctcaggacgtggccaaccgcttc gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaagaaccacaaattcatc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt ggtaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa tttgtcactttttcttgtcctggggcggataagggaccggacactgacgaccccaggagc aagcacaagtttaaaatccacacttatggaagccccaccttctgtgatcactgtgggtca ttgctgtatggacttatccatcaagggatgaaatgtgacacctgtgatatgaacgtgcac aagcagtgtgtgatcaacgtccccagcctctgcgggatggaccacacagagaagaggggc cggatctacctgaaggccgaggtcaccgatgaaaagctccatgtcactgtacgagatgca aaaaatctaattccgatggatccaaacgggctttcagatccttacgtgaagctgaaactc atccctgatcccaagaatgaaagcaagcagaaaaccaaaaccatccgctccacgctgaac cctcagtggaatgagtccttcacgttcaaattgaaaccttctgacaaagaccgacggctg tccgtagaaatctgggactgggatcgaaccacaaggaatgatttcatgggatccctttcc tttggagtctcggagctgatgaagatgccagccagtggatggtacaagttgcttaaccaa gaagaaggtgagtactacaacgtacccattccagaaggagatgaagaaggaaacatggag ctcaggcagaaattcgagaaagccaagcttggccctgctggtaacaaagtcatcagtcct tcagaagaccgaagacaaccttccaacaaccttgacagagtgaaactcacagacttcaat ttcctcatggtgctggggaaggggagttttggaaaggtgatgctcgccgacaggaagggg acagaagaactgtacgccatcaaaatcctgaagaaggacgtggtgattcaggacgatgat gtggagtgcaccatggtggagaagcgagtcctggccttgcttgacaagcccccgttcctg acacagctacattcctgcttccagacagtggatcgactgtactttgtcatggaatacgtc aacggtggagacctgatgtaccacattcagcaagtagggaagtttaaggaaccacaagca gtattttatgcagcagagatctccattggattgttctttcttcataaaagaggaatcatt tacagggatctgaagttagacaacgtcatgctggactcggaagggcacatcaagattgct gacttcgggatgtgcaaagaacacatgatggatggagtcacaaccaggaccttctgtggg actccagattacattgccccagagataatcgcttatcagccgtatgggaaatccgtggac tggtgggcctatggcgttctgttatatgaaatgctagccgggcagcctccatttgatggc gaagatgaagacgagctgtttcaatcgataatggagcataacgtttcttacccaaaatcc ttgtccaaggaggccgtttccatctgcaaaggactgatgaccaaacaccccggcaagcgg ctgggctgcgggcccgagggggagagggacgtgcgggagcatgccttcttccggaggatc gactgggagaaactcgagaacagggagatccaaccacccttcaagcccaaagtgtgtggc aaaggcgcagaaaactttgacaagttcttcacgcgagggcagcctgtcttaacaccacct gatcagctggtcattgctaacatagaccagtctgattttgaggggttctcatatgtcaac ccccagtttgtgcaccccatcttacagagtgcggtatga

DBGET integrated database retrieval system