Hyaena hyaena (striped hyena): 120234198
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Entry
120234198 CDS
T07257
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv04140
Autophagy - animal
hhv04141
Protein processing in endoplasmic reticulum
hhv04210
Apoptosis
hhv04932
Non-alcoholic fatty liver disease
hhv05010
Alzheimer disease
hhv05012
Parkinson disease
hhv05014
Amyotrophic lateral sclerosis
hhv05016
Huntington disease
hhv05017
Spinocerebellar ataxia
hhv05022
Pathways of neurodegeneration - multiple diseases
hhv05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
120234198 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
120234198 (ERN1)
09143 Cell growth and death
04210 Apoptosis
120234198 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
120234198 (ERN1)
05012 Parkinson disease
120234198 (ERN1)
05014 Amyotrophic lateral sclerosis
120234198 (ERN1)
05016 Huntington disease
120234198 (ERN1)
05017 Spinocerebellar ataxia
120234198 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
120234198 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
120234198 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
120234198 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hhv01001
]
120234198 (ERN1)
Enzymes [BR:
hhv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
120234198 (ERN1)
Protein kinases [BR:
hhv01001
]
Serine/threonine kinases: Other
IRE family
120234198 (ERN1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
120234198
NCBI-ProteinID:
XP_039091866
LinkDB
All DBs
Position
Unknown
AA seq
972 aa
AA seq
DB search
MPVRLLLALLLSGLGTFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQ
VPTHVEEPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQD
IWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYA
ASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHI
NVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEG
VAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFEPGLKGKNKLNYLRNYWLLIG
HHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVEQTSENAPTAVSQDVE
EKFEHAPAKPEAPVDSVLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKEL
EKIQLLQQQQLPFHPPGDVAPDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSSGSASR
AGTSPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPEC
FSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLEP
ITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSF
SRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANI
LLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWGLEKQLQFFQDV
SDRIEKESLDGPIVKQLERGGRAVVKTDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMR
NKKHHYRELPAEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMEPCSHERLFQPYYFHEP
PELRPPVTPDTL
NT seq
2919 nt
NT seq
+upstream
nt +downstream
nt
atgccggtccggctgctgctggcgctgctgctgtccggcctcgggacttttggaagtccc
agcacagtgacgcttcccgaaaccttgctgtttgtgtcaaccctggatggaagcttgcat
gcggtcagcaagaggacaggctccatcaaatggactttaaaagaagatcctgttctgcag
gttccaacgcatgtggaagagcctgccttcctcccagatcccaatgacggcagcctgtac
acgcttgggagcaagaataatgaaggcctgacgaaacttccctttaccatcccagagctc
gtacaggcatccccatgccgaagttcagatggaattctctacatgggtaaaaagcaggac
atttggtatgtaattgacctcctgaccggggagaagcagcagactttgtcatcagccttt
gcagacagtctctgcccatcgacttctctgctgtatctcgggcgaacagagtacaccatc
accatgtacgacaccaaaacccgcgagctccggtggaatgccacctacttcgactatgcg
gcctcgctgccagaggacgacggggactacaagatgtcccactttgtgtccaatggcgat
gggctggtggtgaccgtggacagtgaatctggcgacgtcctgtggatccaaaactatgct
tcccctgtggtggccttttatgtctggcagcgggagggtctgaggaaggtgatgcacatc
aacgtcgcggtggagaccctgcgctacctgaccttcatgtctggggaggtgggccgcatc
accaagtggaagtacccgttccccaaggagacggaggccaagagcaagctgacgcccacc
ctgtatgtcgggaaatactccaccagcctgtacgcctccccctccatggtacatgagggc
gtcgccgttgtgccccgaggcagcacacttcctttgctggaaggtccccagactgacggg
gtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagacctaaagtttgag
cctgggctcaaagggaagaacaagctcaactacttgaggaactactggcttctgatagga
caccatgaaacccccctgtctgcgtctaccaagatgctggagagattccccaataatctg
cccaaacatcgggaaaacgtgattcctgctgattcagagaagaagagctttgaggaagtt
atcaacctggttgagcagacttcagaaaacgcgcccaccgccgtttcacaggatgtggag
gagaagttcgagcacgcccctgccaagcccgaggcccccgtggactctgtgctcaaggat
atagccaccatcatcctgagcaccttcctgctcatcggctgggtggccttcatcattacc
taccccttgagcatgcatcagcagcagcagctccagcaccagcagttccagaaggaactg
gagaaaatccagctcctgcaacagcagcagctgcccttccatccccctggagacgtggct
ccagatgccgagcttctggactcctccggcctgtactcggagagctcgggcaccagcagc
cccagcacatcccccagagcctccaaccactcgctccactccagtggctctgcctccagg
gctggcaccagccccttcctggagcaggacgatgaggatgaggaaaccagcatggtgatc
gttgggaagatctcattctgtcccaaggacgtgctgggccatggagcggaaggcacgatt
gtgtaccggggcatgtttgacaaccgcgacgtggccgtcaagaggatcctccctgagtgt
tttagtttcgcggaccgtgaggtccagctgcttcgagaatcagacgagcaccccaatgtg
attcgttacttctgcacggagagggaccggcagttccagtacattgccatcgagctgtgt
gcggccacgctgcaggagtacgtggagcaaaaggactttgcccacctcggcctggagccc
atcaccttgctgcagcagaccacctcgggcctggcccatctgcactccctcaacatcgtt
cacagagacctgaagccccacaacattctcctgtccatgcccaacgcacatggcaggatc
aaggccatgatctctgactttggcctctgcaagaagctggcggtgggcaggcacagtttc
agccgccgctcgggggtgcctggcacagaaggctggatcgctccagagatgctgagcgaa
gactgtaaggacaatcccacctacacagtggacatcttctctgccggctgtgtcttttac
tatgtgatatctgagggcagtcaccctttcggcaagtccctgcagcggcaagccaacatc
ctcctgggcgcctacagcctcgactgcttacatccggagaagcatgaagacgtcattgcc
cgggagttaatcgagaagatgattgcaatggaccctcagaaacgcccatctgcgaagcac
gtgctgaagcacccgttcttctggggcctggaaaagcagctccagttcttccaggacgtg
agtgaccggatagaaaaggaatccctggacggcccgatagtgaagcagctggagcgaggc
gggagagccgtggtgaagacggactggagagagaacattaccgtccccctgcagacagat
ctgcgtaaattcagaacctataaaggtggctccgtgcgagaccttctccgagccatgaga
aacaagaagcaccactaccgggagctccccgcagaggtgcgggagacgctgggctctctc
cctgacgactttgtgcgctacttcacatcacgcttcccccatctcctctcccacacctac
cgggccatggagccctgcagccacgagaggctcttccagccctactatttccacgagccc
ccagagctccggcccccagtgactccagacaccctttga
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