KEGG   Hyaena hyaena (striped hyena): 120235229
Entry
120235229         CDS       T07257                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
hhv  Hyaena hyaena (striped hyena)
Pathway
hhv04010  MAPK signaling pathway
hhv04022  cGMP-PKG signaling pathway
hhv04137  Mitophagy - animal
hhv04141  Protein processing in endoplasmic reticulum
hhv04151  PI3K-Akt signaling pathway
hhv04210  Apoptosis
hhv04211  Longevity regulating pathway
hhv04261  Adrenergic signaling in cardiomyocytes
hhv04668  TNF signaling pathway
hhv04720  Long-term potentiation
hhv04722  Neurotrophin signaling pathway
hhv04725  Cholinergic synapse
hhv04728  Dopaminergic synapse
hhv04911  Insulin secretion
hhv04912  GnRH signaling pathway
hhv04915  Estrogen signaling pathway
hhv04918  Thyroid hormone synthesis
hhv04922  Glucagon signaling pathway
hhv04925  Aldosterone synthesis and secretion
hhv04926  Relaxin signaling pathway
hhv04927  Cortisol synthesis and secretion
hhv04928  Parathyroid hormone synthesis, secretion and action
hhv04932  Non-alcoholic fatty liver disease
hhv04934  Cushing syndrome
hhv04935  Growth hormone synthesis, secretion and action
hhv05010  Alzheimer disease
hhv05012  Parkinson disease
hhv05014  Amyotrophic lateral sclerosis
hhv05020  Prion disease
hhv05022  Pathways of neurodegeneration - multiple diseases
hhv05030  Cocaine addiction
hhv05031  Amphetamine addiction
hhv05034  Alcoholism
hhv05161  Hepatitis B
hhv05163  Human cytomegalovirus infection
hhv05166  Human T-cell leukemia virus 1 infection
hhv05203  Viral carcinogenesis
hhv05207  Chemical carcinogenesis - receptor activation
hhv05215  Prostate cancer
hhv05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hhv00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    120235229 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120235229 (ATF4)
   04668 TNF signaling pathway
    120235229 (ATF4)
   04022 cGMP-PKG signaling pathway
    120235229 (ATF4)
   04151 PI3K-Akt signaling pathway
    120235229 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    120235229 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    120235229 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    120235229 (ATF4)
   04922 Glucagon signaling pathway
    120235229 (ATF4)
   04912 GnRH signaling pathway
    120235229 (ATF4)
   04915 Estrogen signaling pathway
    120235229 (ATF4)
   04926 Relaxin signaling pathway
    120235229 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    120235229 (ATF4)
   04918 Thyroid hormone synthesis
    120235229 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    120235229 (ATF4)
   04925 Aldosterone synthesis and secretion
    120235229 (ATF4)
   04927 Cortisol synthesis and secretion
    120235229 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    120235229 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    120235229 (ATF4)
   04728 Dopaminergic synapse
    120235229 (ATF4)
   04720 Long-term potentiation
    120235229 (ATF4)
   04722 Neurotrophin signaling pathway
    120235229 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    120235229 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    120235229 (ATF4)
   05203 Viral carcinogenesis
    120235229 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    120235229 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    120235229 (ATF4)
   05161 Hepatitis B
    120235229 (ATF4)
   05163 Human cytomegalovirus infection
    120235229 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    120235229 (ATF4)
   05012 Parkinson disease
    120235229 (ATF4)
   05014 Amyotrophic lateral sclerosis
    120235229 (ATF4)
   05020 Prion disease
    120235229 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    120235229 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    120235229 (ATF4)
   05031 Amphetamine addiction
    120235229 (ATF4)
   05034 Alcoholism
    120235229 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    120235229 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    120235229 (ATF4)
   04934 Cushing syndrome
    120235229 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hhv03000]
    120235229 (ATF4)
Transcription factors [BR:hhv03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    120235229 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 CEP89 DUF4407 BNI5_helical MCU NOCA1_mid KIF21A Asd-4 DUF3450 OVT1 AAA_13 Nop53
Other DBs
NCBI-GeneID: 120235229
NCBI-ProteinID: XP_039093372
LinkDB
Position
Unknown
AA seq 352 aa
MAEMMSFLSSEVLEGDLMSPFDQSGLGAEVSLGLLDDYLEVAKHFKPHGFSSDKAKAGSS
EWLAVDGLVGASDNGKEDAFSGTDWMVEKMDLKEFDFDSLFSIDDLETMPDELLATLDDT
CDLFDPLVQETDKEPPQTVNPIGHLPESLPKTDQVAPFTFLQSLPLSPGALSSTPDHSFS
LELGSEVDISEGDRKPDSTAYILMIPQCIKEEDAPSDNDSGICMSPESYLGSPQHSPSTS
RGSPNKSLLSPCSLCGSARPKPYDPPGEKAAAKVKVEKLDKKLKKMEQNKTAATRYRQKK
RAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKAREKKRVP
NT seq 1059 nt   +upstreamnt  +downstreamnt
atggccgagatgatgagcttcctgagcagcgaggtgttggagggggacttgatgtccccc
ttcgaccagtcgggtttgggggctgaagtaagcctagggctcttagacgattacctggag
gtggccaagcacttcaaaccccatgggttctccagcgacaaggctaaggcgggctcctcc
gaatggctggctgtggatgggttggtcggtgcctcagacaacggcaaggaggatgccttc
tccgggacagattggatggtggagaaaatggacctgaaggagtttgattttgattctctg
ttcagtatagatgacctggaaaccatgccagatgagcttttggccactttggatgacaca
tgtgatctctttgaccccctagtccaggagactgataaggagcccccccagaccgtgaac
ccgattggccatctcccagaaagtttacccaaaacagaccaggttgccccttttaccttc
ctgcaatctcttcctctctcccccggggccttgtcctccactccagatcattcctttagt
ttagagttgggcagtgaggtggatatctcggaaggagatagaaagccagactcgactgct
tatattctaatgatccctcagtgcataaaggaggaggatgccccctctgataatgatagt
ggcatctgtatgagtcctgagtcctatctggggtccccccagcatagcccctctacttcg
aggggctctccaaataagagcctgctgtctccatgttccctctgtggttctgcccgcccc
aaaccctatgatcctcctggagagaaagccgcagcaaaagtaaaggtggaaaaattggat
aagaagctgaaaaaaatggagcagaacaagacagcagccactaggtaccgccagaagaag
agggccgagcaggaggcccttactggcgagtgtaaagagctagaaaagaagaatgaggct
ctgaaagagcgggcagattctttggccaaggaaatccagtatctgaaggatttgatagaa
gaggttcggaaggcccgggagaagaaaagggtcccctag

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