Hyaena hyaena (striped hyena): 120236301
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Entry
120236301 CDS
T07257
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv03060
Protein export
hhv04141
Protein processing in endoplasmic reticulum
hhv04612
Antigen processing and presentation
hhv04918
Thyroid hormone synthesis
hhv05012
Parkinson disease
hhv05014
Amyotrophic lateral sclerosis
hhv05020
Prion disease
hhv05022
Pathways of neurodegeneration - multiple diseases
hhv05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
120236301 (HSPA5)
04141 Protein processing in endoplasmic reticulum
120236301 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
120236301 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
120236301 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
120236301 (HSPA5)
05014 Amyotrophic lateral sclerosis
120236301 (HSPA5)
05020 Prion disease
120236301 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
120236301 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
120236301 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
hhv03110
]
120236301 (HSPA5)
04131 Membrane trafficking [BR:
hhv04131
]
120236301 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hhv04147
]
120236301 (HSPA5)
Enzymes [BR:
hhv01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
120236301 (HSPA5)
Chaperones and folding catalysts [BR:
hhv03110
]
Heat shock proteins
HSP70 / DNAK
120236301 (HSPA5)
Membrane trafficking [BR:
hhv04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
120236301 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
120236301 (HSPA5)
Exosome [BR:
hhv04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
120236301 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
120236301 (HSPA5)
Exosomal proteins of colorectal cancer cells
120236301 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
120236301
NCBI-ProteinID:
XP_039094966
LinkDB
All DBs
Position
Unknown
AA seq
654 aa
AA seq
DB search
MKLSLVAAVLLLLGAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGDEEPADKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgtccctggtggccgcggtgctgctgctgctcggcgcggcacgggccgaggag
gaggacaagaaggaggacgtgggcacggtggtcggcatcgacctggggaccacctactcc
tgcgtcggggtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaatcgc
atcacgccgtcttatgtggccttcactcctgaaggggagcggctgatcggcgatgcagcc
aagaaccagctcacctccaaccctgagaacactgtcttcgacgccaagcggctcatcggc
cgcacatggaacgacccatctgtgcagcaggacataaagttcttgcctttcaaggtggtt
gaaaagaaaactaaaccatatattcaagttgatattggaggagggcaaacaaagacattt
gctcctgaagaaatttctgccatggttctcactaaaatgaaggaaactgctgaggcttat
ttgggaaagaaggttacccatgcagttgttactgtaccagcctattttaacgatgcccaa
cgccaggcaaccaaagatgctggaactattgctggattgaatgttatgagaatcatcaat
gagcctacagcagctgccattgcttatggcttggataaaagggaaggggagaagaacatc
ctggtatttgacctcggtggtggaacttttgatgtgtctcttctcaccatcgataatggt
gtttttgaagtcgtggctactaatggagacactcatttgggtggagaagactttgaccaa
cgtgtcatggaacacttcatcaagctctacaaaaagaagactggcaaagatgtcaggaaa
gacaacagagctgtgcagaaactccgacgtgaggtagaaaaggccaaacgggccctgtct
tctcaacatcaagcaagaattgaaattgagtctttctatgaaggagaagacttctctgaa
actctgactcgggccaaatttgaagagctaaacatggacctgttccgttctaccatgaag
cctgtccagaaggtgctggaggattctgacttaaagaagtctgatattgatgaaattgtt
cttgttggtggctctactcgaattccaaagattcaacaactggttaaagagttcttcaat
ggcaaggagccatcccgtggcataaacccagatgaggctgtagcatatggtgctgctgtc
caggctggggtactctctggtgatcaagatacaggtgatctggtactgcttgatgtatgt
ccccttacacttggtattgagactgtgggaggtgtcatgaccaaactgattccaaggaac
accgtggtgcccaccaagaagtctcagatcttttctacagcttctgataatcaaccaact
gttacgatcaaggtctatgaaggtgaacgacccctgaccaaagacaatcacctcctggga
acttttgatctgactggaattcctcctgctcctcgtggggtcccacagattgaagtcacc
tttgaaatagatgtgaatggcattcttcgagtgacagccgaagacaaaggtacaggtaac
aaaaataagatcacaattaccaatgaccaaaatcgcctgacacctgaagaaattgaaagg
atggttaatgatgctgagaagtttgccgaggaagacaagaagctcaaggagcgcattgat
actagaaatgagttggaaagctatgcctactctctaaagaatcagattggagataaagaa
aagctgggaggtaaactctcttctgaagacaaggagaccatggaaaaagccgtagaggaa
aagattgaatggctagaaagtcaccaagatgctgacattgaagatttcaaagctaaaaag
aaggaactagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggccct
cccccaactggtgatgaagaaccagcagataaagatgagttgtag
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