Hyaena hyaena (striped hyena): 120237374
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Entry
120237374 CDS
T07257
Symbol
IDH1
Name
(RefSeq) isocitrate dehydrogenase [NADP] cytoplasmic
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv00020
Citrate cycle (TCA cycle)
hhv00480
Glutathione metabolism
hhv01100
Metabolic pathways
hhv01200
Carbon metabolism
hhv01210
2-Oxocarboxylic acid metabolism
hhv01230
Biosynthesis of amino acids
hhv04146
Peroxisome
hhv05230
Central carbon metabolism in cancer
Module
hhv_M00009
Citrate cycle (TCA cycle, Krebs cycle)
hhv_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
120237374 (IDH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
120237374 (IDH1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
120237374 (IDH1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
120237374 (IDH1)
Enzymes [BR:
hhv01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
120237374 (IDH1)
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Motif
Pfam:
Iso_dh
XRN1_D2_D3
Motif
Other DBs
NCBI-GeneID:
120237374
NCBI-ProteinID:
XP_039096581
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All DBs
Position
Unknown
AA seq
414 aa
AA seq
DB search
MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATGDQVTKDA
AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEIAYTSSDGSKKMTYLVHNFEEGGGVAM
GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDDNKELSFFAKALE
EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAKL
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgtctcaaaaaatccgtggcggttctgtggtagagatgcaaggagatgaaatgacacga
atcatttgggagttgattaaagaaaaactcatttttccctacgtggaactggacctgcac
agctatgatttaggcatagagaatcgcgatgccaccggtgaccaggtcaccaaagatgct
gcagaagctataaagaagtacaacgttggtgtcaaatgtgctaccatcacccccgatgag
aagagggttgaggagttcaagctgaaacaaatgtggaagtcaccaaatggcaccatccga
aatattctgggtggcactgtcttcagggaagctatcatctgcaaaaatatcccccggctt
gtgagcggatgggtaaaacctatcatcataggacgccatgcttatggggatcaatacaga
gccaccgattttgttgttcctgggcctggaaaagtagagatagcctacacatcaagtgat
ggatccaaaaaaatgacgtacctggtacataactttgaagagggtggtggtgttgccatg
gggatgtacaatcaagataagtcgattgaagattttgcacacagttccttccagatggct
ctgtctaagagttggcctttgtatttgagcaccaagaacactattctgaagaaatatgac
ggccgttttaaagacatctttcaggaaatctatgacaagcagtacaaatcccagttcgaa
gcccaaaatatttggtatgagcacaggctcattgatgacatggtggcccaagctatgaaa
tccgaggggggcttcatctgggcctgtaaaaactatgatggcgatgtgcagtcagactcc
gtggcccaaggttatggctcccttggcatgatgaccagcgtgctggtttgtccagacggc
aagacagtggaagcagaggcggcccatgggactgtgacacgtcactaccgcatgtatcag
aaaggacaagagacgtccaccaatcccattgcttccatttttgcttggaccagaggattg
gcgcacagagcgaagctggatgacaataaagagctcagcttctttgcaaaggctttggag
gaagtctgtattgagaccattgaggctggtttcatgaccaaggacttggctgcttgtatt
aaaggtttgcctaacgtgcaacgttctgactacttgaatacatttgagttcatggacaaa
ctcggagaaaacttgaatataaaactagctcaggccaaactctaa
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