Hyaena hyaena (striped hyena): 120237461 Help Entry 120237461         CDS       T07257                                  Symbol HIF1A Name (RefSeq) hypoxia-inducible factor 1-alpha   KO K08268   hypoxia-inducible factor 1 alpha Organism hhv  Hyaena hyaena (striped hyena) Pathway hhv04066   HIF-1 signaling pathway hhv04137   Mitophagy - animal hhv04140   Autophagy - animal hhv04148   Efferocytosis hhv04659   Th17 cell differentiation hhv04919   Thyroid hormone signaling pathway hhv05167   Kaposi sarcoma-associated herpesvirus infection hhv05200   Pathways in cancer hhv05205   Proteoglycans in cancer hhv05208   Chemical carcinogenesis - reactive oxygen species hhv05211   Renal cell carcinoma hhv05230   Central carbon metabolism in cancer hhv05231   Choline metabolism in cancer hhv05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:hhv00001]  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     120237461 (HIF1A)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     120237461 (HIF1A)    04137 Mitophagy - animal     120237461 (HIF1A)    04148 Efferocytosis     120237461 (HIF1A)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     120237461 (HIF1A)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     120237461 (HIF1A)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     120237461 (HIF1A)    05205 Proteoglycans in cancer     120237461 (HIF1A)    05208 Chemical carcinogenesis - reactive oxygen species     120237461 (HIF1A)    05230 Central carbon metabolism in cancer     120237461 (HIF1A)    05231 Choline metabolism in cancer     120237461 (HIF1A)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     120237461 (HIF1A)   09162 Cancer: specific types    05211 Renal cell carcinoma     120237461 (HIF1A)   09172 Infectious disease: viral    05167 Kaposi sarcoma-associated herpesvirus infection     120237461 (HIF1A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:hhv03000]     120237461 (HIF1A) Transcription factors [BR:hhv03000]  Eukaryotic type   Basic helix-loop-helix (bHLH)    Factors with PAS domain     120237461 (HIF1A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  bHLH_HIF1A PAS_3 PAS_11 HIF-1a_CTAD PAS HIF-1 PAS_9 PAS_4 HLH DDRGK Motif Other DBs NCBI-GeneID:  120237461 NCBI-ProteinID:  XP_039096695 LinkDB All DBs Position Unknown AA seq 823 aa AA seqDB search MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR TMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV LKPVESSDMKMTQLFTKVESEDASSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET DDQQLEEVPLYNDVMLPSSNEKLQNINLAMSPLPASETPKPLRSSADPALNQEVVLKLEP NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNEFKLELVEKLF AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTSPQSVGTITVFQ PAQVQEPPLTTASTTATTDELKTVTKDGIEDIKILIASPSPTHVPKVTTGATTSLYGDTG SRTASPNRAGKGVIEQTEKSHPRSPNVLSVTLSQRSTIPEEELNPKILALQNAQRKRKIE NDGSLFQAVGIGTLLQQPDDRATTTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRLL GQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN NT seq 2472 nt NT seq  +upstreamnt  +downstreamnt atggagggcgccggcggcgcgaacgacaagaaaaagataagttctgaacgtcgaaaagaa aagtctagagatgcagcgagatctcggcgaagtaaagagtctgaagttttctatgagctt gctcatcagttaccacttccccataatgtgagctcgcatcttgataaggcttctgttatg aggctcaccatcagctatttgcgtgtgaggaaacttctggatgctggtgatttagatatt gaagatgaaatgaaggcacagatgaattgcttttatttgaaagccctggatggttttgtt atggttctcacagatgatggtgatatgatctacatttctgataatgtgaacaaatacatg ggattgactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac catgaagaaatgagagaaatgcttacacatagaaatggccttgtgaagaagggtaaagag cagaatacacagcgaagcttttttctcagaatgaaatgtaccctaactagccgggggaga accatgaacataaagtcagcaacatggaaagtacttcactgcacaggccatattcatgtc tacgataccaatagtaaccaatctcagtgtgggtataagaaaccacccatgacatgcttg gtgctgatttgtgaacccattcctcatccatcaaatattgaaattcctttagatagcaag acttttctcagtcgtcacagtctggatatgaaattttcttactgtgatgaaagaattact gaattgatgggatatgagccagaggaacttttgggccgctcaatttatgaatattaccat gctttggactctgaccatctgaccaaaactcatcatgatatgtttactaaaggacaagtc accacaggacagtacaggatgcttgctaaaagaggtggatatgtctgggttgaaactcaa gcaaccgtcatatataacactaagaactctcaaccacagtgcattgtatgtgtaaattat gttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc ctcaagccagttgaatcttcagatatgaaaatgactcagctgttcaccaaagttgaatca gaagacgcaagtagtctctttgataaacttaagaaggaacctgatgctttaactttgctg gccccagctgctggagacacaatcatatctttagatttcggcagcaatgacacagaaact gatgaccaacaacttgaggaagttccactgtataatgatgtaatgcttccctcatccaat gaaaaattacagaacataaatttggcaatgtctccattacctgcttctgaaacaccgaag ccacttcgaagtagtgctgaccctgcactcaatcaagaagttgtactaaaattagagcca aacccagagtcactggaactgtcttttactatgccccagattcaagatcagccagctagt ccttctgatggaagcactagacagagttcacctgagcccaacagtcccagtgaatattgt tttgatgtggatagtgatatggtcaatgaatttaagctggaattggtagagaaacttttt gctgaagacacagaagccaagaatccattttccacccaggacactgatttagacttggag atgttagctccgtacatcccaatggatgatgacttccagttacgttccttcgatcagttg tcgccactggaaagcagttctacaagccctcagagtgtgggcacaatcacagtattccag ccagctcaagtgcaggagcctcctcttaccactgccagtaccaccgccaccaccgatgaa ttaaaaacagtgacaaaagatggcatagaagacattaaaatattgattgcatctccatct cctacccacgtacctaaagttactactggtgccacaacatcactgtatggtgatactgga agtcggacagcctcaccaaacagagcaggaaaaggggtcatagaacagacggaaaaatct catccaagaagtcctaatgtgttatctgtcactttgagtcaaagaagtaccattcctgag gaggaactaaatccaaagatactagctttgcagaatgctcagagaaagcgaaaaatagaa aatgacggttcactttttcaagctgtaggaattggaacattattacagcagccagatgat cgtgcaactactacatcactttcttggaaacgtgtaaaaggatgcaaatctagtgagcag aatggaatggagcaaaagacaattattttaataccctctgatttagcatgtagactgctg gggcaatcaatggatgagagtggattaccacaactgaccagttatgattgtgaagttaat gctcctatacaaggcagcagaaacctactgcagggtgaagaattactcagagctttggat caagttaactga

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