Hyaena hyaena (striped hyena): 120238910 Help Entry 120238910         CDS       T07257                                  Symbol GCK Name (RefSeq) hexokinase-4 isoform X1   KO K12407   glucokinase [EC:2.7.1.2] Organism hhv  Hyaena hyaena (striped hyena) Pathway hhv00010   Glycolysis / Gluconeogenesis hhv00052   Galactose metabolism hhv00500   Starch and sucrose metabolism hhv00520   Amino sugar and nucleotide sugar metabolism hhv00524   Neomycin, kanamycin and gentamicin biosynthesis hhv01100   Metabolic pathways hhv01200   Carbon metabolism hhv01250   Biosynthesis of nucleotide sugars hhv04910   Insulin signaling pathway hhv04911   Insulin secretion hhv04917   Prolactin signaling pathway hhv04922   Glucagon signaling pathway hhv04930   Type II diabetes mellitus hhv04950   Maturity onset diabetes of the young hhv05230   Central carbon metabolism in cancer Module hhv_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate hhv_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:hhv00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     120238910 (GCK)    00052 Galactose metabolism     120238910 (GCK)    00500 Starch and sucrose metabolism     120238910 (GCK)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     120238910 (GCK)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     120238910 (GCK)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     120238910 (GCK)    04910 Insulin signaling pathway     120238910 (GCK)    04922 Glucagon signaling pathway     120238910 (GCK)    04917 Prolactin signaling pathway     120238910 (GCK)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     120238910 (GCK)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     120238910 (GCK)    04950 Maturity onset diabetes of the young     120238910 (GCK) Enzymes [BR:hhv01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.2  glucokinase      120238910 (GCK) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  120238910 NCBI-ProteinID:  XP_039098922 LinkDB All DBs Position Unknown AA seq 465 aa AA seqDB search MLDDRARMEATKKEKAEQILADFQLQEADLKKVMWRMQKEMARGLRLETHEEASVKMLPT YVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAE MLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNN IVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMQN VELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLYEKLIGGKYMGE LVRLVLLKLVDENLLFRGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLRPT ATDCDIVRRACESVSTRAAHMCAAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFK ERFHAIVRKLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ NT seq 1398 nt NT seq  +upstreamnt  +downstreamnt atgctggatgacagagccaggatggaggccaccaagaaggagaaggcagagcagatcctg gcagacttccagctgcaggaagctgacctgaagaaggtgatgtggcggatgcagaaggag atggcacgaggcctgcggctggagacccacgaggaggccagtgtgaagatgctgcccacc tacgtgcgctccaccccagaaggctctgaagtcggggacttcctctccctggacctgggc ggcaccaacttcagggtgatgctggtgaaggtgggggagggcgaagaggggcagtggagt gtgaagaccaagcaccagatgtattccatccccgaggatgccatgaccggtactgctgaa atgctctttgactacatctctgagtgcatctctgacttcctggacaagcatcagatgaag cataagaagcttcccttgggcttcacattctcctttcccgtgaggcatgaagacatcgac aagggcatcctcctcaattggaccaagggcttcaaggcctcgggagcagaagggaacaac atcgtggggctcctacgtgacgccatcaaacggcgaggggactttgaaatggacgtggtg gcgatggtgaatgacaccgtggccacgatgatctcctgctactatgaagaccgccgctgt gaggtcggcatgattgtgggcacaggctgcaatgcctgctacatggaggagatgcagaac gtggaactggtggaaggggatgagggccgcatgtgtgtcaacaccgagtggggcgccttc ggggactccggggagctggacgagttcctgctggagtacgaccgcgtggtggatgagaac tccctgaaccccgggcagcagctgtacgagaagctcatcggtggcaagtacatgggcgag ctggtgcggctcgtgctgctgaagctcgtggacgagaacctgctcttccgcggggaggcc tcggagcagctgcgcacgcgcggcgccttcgagacgcgcttcgtgtcgcaggtggagagc gactctggcgaccgcaagcagatctacaacatcctaagcacgctggggctgaggcccacg gccaccgactgcgacatcgtgcgccgcgcctgcgagagcgtgtccacgcgggcggcacac atgtgcgccgcggggctggcaggcgtcatcaaccgcatgcgcgagagccgcagcgaggac gtgatgcgcattaccgtgggcgtggatggctcggtgtacaagctgcaccccagcttcaag gagaggttccatgccatcgtgcgcaagctgacacccagctgcgagatcaccttcatcgag tcagaggagggcagcggccgaggcgcggccctggtgtccgcagtggcctgtaagaaggcc tgcatgctgggccagtga

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