Hyaena hyaena (striped hyena): 120239388
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Entry
120239388 CDS
T07257
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv04010
MAPK signaling pathway
hhv04020
Calcium signaling pathway
hhv04022
cGMP-PKG signaling pathway
hhv04024
cAMP signaling pathway
hhv04218
Cellular senescence
hhv04260
Cardiac muscle contraction
hhv04261
Adrenergic signaling in cardiomyocytes
hhv04270
Vascular smooth muscle contraction
hhv04530
Tight junction
hhv04713
Circadian entrainment
hhv04723
Retrograde endocannabinoid signaling
hhv04724
Glutamatergic synapse
hhv04725
Cholinergic synapse
hhv04726
Serotonergic synapse
hhv04727
GABAergic synapse
hhv04728
Dopaminergic synapse
hhv04911
Insulin secretion
hhv04912
GnRH signaling pathway
hhv04921
Oxytocin signaling pathway
hhv04924
Renin secretion
hhv04925
Aldosterone synthesis and secretion
hhv04927
Cortisol synthesis and secretion
hhv04929
GnRH secretion
hhv04930
Type II diabetes mellitus
hhv04934
Cushing syndrome
hhv04935
Growth hormone synthesis, secretion and action
hhv04973
Carbohydrate digestion and absorption
hhv05010
Alzheimer disease
hhv05020
Prion disease
hhv05022
Pathways of neurodegeneration - multiple diseases
hhv05031
Amphetamine addiction
hhv05207
Chemical carcinogenesis - receptor activation
hhv05410
Hypertrophic cardiomyopathy
hhv05412
Arrhythmogenic right ventricular cardiomyopathy
hhv05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
120239388 (CACNA1D)
04020 Calcium signaling pathway
120239388 (CACNA1D)
04024 cAMP signaling pathway
120239388 (CACNA1D)
04022 cGMP-PKG signaling pathway
120239388 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
120239388 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
120239388 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
120239388 (CACNA1D)
04929 GnRH secretion
120239388 (CACNA1D)
04912 GnRH signaling pathway
120239388 (CACNA1D)
04921 Oxytocin signaling pathway
120239388 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
120239388 (CACNA1D)
04924 Renin secretion
120239388 (CACNA1D)
04925 Aldosterone synthesis and secretion
120239388 (CACNA1D)
04927 Cortisol synthesis and secretion
120239388 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
120239388 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
120239388 (CACNA1D)
04270 Vascular smooth muscle contraction
120239388 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
120239388 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
120239388 (CACNA1D)
04727 GABAergic synapse
120239388 (CACNA1D)
04725 Cholinergic synapse
120239388 (CACNA1D)
04728 Dopaminergic synapse
120239388 (CACNA1D)
04726 Serotonergic synapse
120239388 (CACNA1D)
04723 Retrograde endocannabinoid signaling
120239388 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
120239388 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
120239388 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
120239388 (CACNA1D)
05020 Prion disease
120239388 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
120239388 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
120239388 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
120239388 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
120239388 (CACNA1D)
05414 Dilated cardiomyopathy
120239388 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
120239388 (CACNA1D)
04934 Cushing syndrome
120239388 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hhv04040
]
120239388 (CACNA1D)
Ion channels [BR:
hhv04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
120239388 (CACNA1D)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
120239388
NCBI-ProteinID:
XP_039099535
LinkDB
All DBs
Position
Unknown
AA seq
2183 aa
AA seq
DB search
MMMMMMMKNMHHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIIAEEDPAPCAFSGNGRQCAANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GGGENQGGCGSLWCWWKRRGTAKAGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPP
CDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCH
KLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMAT
FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFI
LYKDGDVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGP
IYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHHEQSKIFNDAMDIL
NMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPTESDNVPVP
TATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAML
FFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKL
CDPESDYSPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPH
HLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNS
DGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDE
VTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISC
DLQDDEPEETKREEEEDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPP
ASDTEKPLFPPAGNSVCHNHHNHNSIGKQAPSSTNANLNNANMSKAAPGKRPSIGNLEHM
SENGHHSSHKRDREPQRRSSIKRTRYYETYIRSDSGDEQFPTICREDPEIHGYFRDPRCL
EEQEYFSGEESYEEAGSPAGSRQNYSYSYYNRYPGSNWDFERPRGYHHPQGFLEDDDSPV
CYDSRRSPRRRLLPPTPTSRRRSSFNFECLRRQSSQEEAPPPPAFPQRTALPLHLMQQQI
MAVAGLDSSKAQKYSPSHSARSWATPPATPPYREWTPCYAPLIQVERLEALDQVNGSLPS
LHRSSWYTDEPGISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDP
KFVSATKHEIADACDLTIDEMESAASNLLNGTVHPRANGGVGPVSHRQDYELQDFGPGYS
DEEPDPGRDEEDLADEMICITTL
NT seq
6552 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaacatgcaccatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccagactccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaaccgtcctgtcttggcaagctgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcacctccgcacccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgtgcccttttctgtttatcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcatatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattctggaacaattaaccaaagaa
acagaaggcggtaaccactccagtggcaagtcaggaggcttcgatgtcaaagccctccga
gcctttcgagtgttacgaccacttcgactagtgtcaggagtacccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgcttttttgctgactcagatatcatagctgaagaggacccagcgccgtgtgcgttctca
gggaatggacgccagtgtgccgccaacggcacagagtgtaggagtggctgggttggccca
aatgggggcatcaccaactttgataactttgcctttgccatgctcaccgtgtttcagtgc
atcaccatggagggctggacagacgtgctctactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattctcaaaggaaagggagaaggctaaagcccgggga
gatttccagaagctccgggagaagcagcagctagaggaggatctaaagggctacttggac
tggatcacccaagcagaggacatcgatcctgagaacgaggaagaaggaggagaagaaagc
aaacgcaacaccagcatgccgaccagcgagacggagtctgtgaacacagaaaacgtgagt
ggcggaggcgagaaccaaggcggctgtgggagtctctggtgctggtggaaaagaagaggc
acggccaaggctgggccctctgggtgccggcggtggggccaagccatctcaaaatccaag
ctcagccgccgctggcgtcgctggaaccgattcaatcgcagaagatgtagggctgctgtg
aagtctgtcacgttttactggctggttattgtcctggtgtttctcaacaccttaaccatt
tcctctgagcactacaaccagcctgattggttgacgcagattcaagatatcgcgaacaaa
gtcctcctggctctgttcacctgcgagatgctggtaaaaatgtacagcttgggtctccag
gcgtattttgtctctctttttaatcgttttgactgcttcgtggtgtgcggtggaattacc
gagaccatcctggtggagctggagatcatgtcccccctggggatctctgtgtttcgatgt
gtgcgcctcttaaggattttcaaggtgaccaggcactggacttccctgagcaacttagtg
gcctccttgttaaactccatgaagtccatcgcttcgctgttgctcctgctttttctcttc
atcatcatcttttctttgcttgggatgcagctgtttggtggcaagtttaattttgacgaa
acgcagaccaagcggagcaccttcgacaatttccctcaagcccttctgacggtattccag
attctgacaggtgaagactggaacgctgtgatgtatgatggcatcatggcctatggcggc
ccgtcgtcctcgggaatgatcgtctgcatctacttcatcatcctcttcatttgtggtaac
tatatcctactgaatgtcttcttggccattgctgtagacaatctggctgatgctgaaagt
ttgaatactgcccagaaagaggaagctgaagagaaggaaaggaaaaagattgccagaaaa
gaaagcctggagaataaaaagaacaataaaccagaggtcaaccagatagccaacagtgac
aataaggttacaattgatgactatcgagaagaggatgaagacaaggacccctacccacct
tgcgatgtaccagtaggggaagaggaagaggaggaggaggaggatgaacctgaggttcca
gctggcccccgtcctcgtagaatctcggagttgaacatgaaggagaaaatcgcccccatc
cctgaagggagcgcattcttcattctgagcaagaccaacccgatccgcgtgggctgccac
aagctcatcaaccaccacatcttcaccaacctcatccttgtcttcatcatgctgagtagc
gccgcccttgctgccgaggaccccatccgcagccactccttccggaacactatactgggt
tactttgactatgcattcacagccatctttacagttgaaatcctgttaaagatggcgacc
tttggagctttcctccacaaaggggctttctgcaggaactacttcaatctgctggatatg
ctggtcgtcggggtatccctggtgtcattcgggatccaatccagtgccatctccgttgtg
aagattctgagggtcttaagggtcctgaggccactcagggcgatcaacagagcgaaagga
cttaagcacgtggtccagtgtgtcttcgtggccatccggaccattggcaacatcatgatc
gtcaccacccttctccagttcatgtttgcctgcatcggggtccagttgttcaagggaaag
ttctatcgctgcacggacgaggccaaaagtaaccctgaagagtgcagggggcttttcatc
ctctacaaggatggggatgttgataaccctgtggtccgtgagaggatctggcaaaacagt
gatttcaactttgacaacgtcctttctgctatgatggcgctgttcacggtctccacattt
gagggctggcctgcgttgctgtataaagccatcgactcaaacggtgagaatgtcggcccc
atctacaactaccgcgtggagatctccatcttcttcatcatctacatcatcatcgtggct
ttcttcatgatgaacatctttgtgggcttcgtcatcgtcacatttcaggagcagggagag
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgtcgaatacgccttg
aaagcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtac
gtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcaccacgagcagtccaagatatttaatgacgccatggacattctg
aacatggtcttcactggggtgttcaccgtcgagatggttttgaaagtcatcgcatttaaa
cctaaggggtactttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagc
attatagacgtggccctcagcgaagccgacccaactgaaagtgacaatgtccctgtccca
accgctacacccgggaactctgaagagagcaatagaatctccatcacctttttccgtctt
ttccgagtgatgcggttggtgaagcttctcagcaggggggaaggcatccggacgctgctg
tggacttttataaagtcctttcaggcactgccctatgttgccctgctcatagccatgctg
tttttcatctacgctgttatcggcatgcagatgtttgggaaggttgctatgagagataac
aaccagatcaacaggaacaacaatttccagacatttccccaggcggtgctgctgctcttc
aggtgtgccacaggggaggcctggcaggagatcatgctggcttgcctcccggggaagctc
tgtgaccccgagtccgactacagccccggggaggagtacacgtgtggcagcaacttcgcc
attgtttacttcatcagtttttacatgctctgcgcgtttctgatcatcaacctgtttgtg
gctgtcatcatggacaactttgattatctgacccgggattggtctattctggggcctcac
catttagatgaattcaaaagaatatggtcagaatacgaccctgaggcaaagggaaggatc
aagcaccttgatgtggtcaccctgctccgccgtatccagcctcccctggggtttgggaag
ctatgcccacacagagtagcctgtaagagacttgttgccatgaacatgcctctcaacagt
gatgggacagtcatgtttaacgcaaccctgtttgctttggttcgaacggctcttaaaatc
aagacagaagggaacctggaacaagctaatgaagagctccgagctgtgataaagaaaatc
tggaagaaaaccagcatgaaactgcttgaccaagttgtccctccagctggtgatgatgag
gtaaccgtggggaagttctatgccactttcctgatacaggactactttaggaaattcaag
aaacggaaagaacaaggcctggtgggaaaataccctgcgaagaacaccaccattgcccta
caggcaggattaaggacactgcatgacattgggccagaaatccggcgtgctatatcatgt
gatttgcaagatgacgagccggaggaaacaaaacgagaagaagaagaagatgtattcaaa
agaaatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagagattcc
cttcagcagaccaataccacccaccgtcccctgcatgtccaaaggccttcaattccacct
gcaagtgatactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataaccat
cataaccataattccataggaaagcaagctcccagctcaacaaatgccaatctcaataat
gccaatatgtccaaagctgcccctggaaagcggcccagcattgggaaccttgagcatatg
tctgaaaacgggcatcactcctcccacaagcgtgaccgtgagcctcaaagaaggtccagt
attaaaagaacccgctattatgaaacttacattaggtctgactcaggagatgagcagttc
ccaactatttgccgggaagatccagagatacatggctacttcagggacccccgctgcttg
gaggagcaggagtatttcagtggtgaggagagctatgaggaggccggctcaccggccggg
agcaggcagaactacagctacagctactacaacagatacccaggcagcaactgggacttc
gagcggcctcgaggctaccatcacccccaaggcttcttggaggatgatgactcacctgtt
tgctatgactcccggagatctccaaggagacgcctactacctcccactccaacatcccgc
cggagatcctccttcaacttcgagtgtctgcgccggcagagcagccaggaggaggccccg
ccgccccccgccttcccccagcgcacagccctgcccctgcacctgatgcagcagcagatc
atggcagttgcaggcctggattccagtaaagcccagaagtactcgccgagccattcagcc
cggtcatgggccacccctccagcgactcctccgtaccgggaatggacgccgtgctatgca
cccctgatccaggtggagcggctggaggccctggaccaggtcaacggcagcctgccgtcc
ctgcaccgaagctcgtggtacacggacgagcccggcatctcgtaccgaactttcacacca
gctagcctgactgtccccagcagcttccgcaacaaaaacagcgacaaacagaggagcgca
gacagcttggtggaagcagtcctaatatccgaaggtttgggaaggtatgcaagggaccca
aaatttgtatcggccacaaaacatgaaatcgccgatgcctgtgacctaaccatcgacgag
atggagagtgcagccagcaacctgctcaatgggaccgtacatccccgagccaacgggggt
gtgggcccggtctcacaccggcaggactatgagctccaggacttcgggccaggctacagc
gatgaagagcctgaccccggaagggatgaggaggacctggcagatgaaatgatatgtatc
accaccctgtag
DBGET
integrated database retrieval system
