Hyaena hyaena (striped hyena): 120241149
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Entry
120241149 CDS
T07257
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv00280
Valine, leucine and isoleucine degradation
hhv00640
Propanoate metabolism
hhv00785
Lipoic acid metabolism
hhv01100
Metabolic pathways
hhv01210
2-Oxocarboxylic acid metabolism
Module
hhv_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
120241149 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
120241149 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
120241149 (BCKDHA)
Enzymes [BR:
hhv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
120241149 (BCKDHA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
120241149
NCBI-ProteinID:
XP_039102017
LinkDB
All DBs
Position
Unknown
AA seq
446 aa
AA seq
DB search
MAVAAAAKLWGSGRGLGRAGHLLLRRFGARGLARYHPQRQEQQQHFPSPDDKPQFPGASA
EFVDKLEFIQPNVISGIPVYRVMDRQGQIINPSEDPHLPQETVLKFYKSMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHVGSAAALDSMDLVFGQYREAGVLMYRDYPLELFMAQCY
GNVSDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANTNRVVICYFGEG
AASEGDAHAGFNFAATLECPVIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVD
GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYLQGRGWWDDEQEKAWRKQSRRKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQ
LRKQQESLARHLQTYGEHYPLDHFEK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggtggcggcggcggcgaagctctggggctcaggtcgaggcttgggccgggctggc
catctgctcctgcggcggtttggtgctcgggggctggctagatatcacccccagagacag
gagcagcagcagcacttcccgtccccggatgacaagccccagttcccaggggcctcggcg
gagtttgtggacaagctcgaattcatccagcccaatgtcatctctgggatccccgtctac
cgcgtcatggaccggcagggccagatcatcaaccccagcgaggatccccacctgccccag
gagacggtgctcaagttctacaagagcatgactctgctcaacaccatggaccgcatcctc
tacgagtcccagcggcagggccggatctccttctacatgaccaactatggcgaggagggg
acacacgtggggagcgcagcagcgctggacagcatggacctggtgttcggccagtaccgg
gaggcaggcgtgctcatgtaccgggactaccccctggagctgttcatggcccagtgctac
ggcaacgtgagcgacctgggcaaggggcgccagatgcccgtgcactacggctgcaaggag
cgccacttcgtcaccatctcttctccactggccacgcagatcccgcaggcggtgggggcg
gcctacgcggccaagcgtgccaacaccaacagagtggtcatctgttacttcggggagggg
gcggccagcgagggggatgcccacgccggcttcaacttcgctgccaccctcgagtgcccc
gtcatcttcttctgccggaacaacggctatgccatctccacgcccacctctgagcagtac
cgcggggacggcatcgctgctcgaggcccgggctacggcatcatgtccatccgcgtggac
ggcaatgacgtgttcgccgtgtacaacgccaccaaggaggcccggcggcgggctgtggcc
gagaaccagcccttcctcattgaggccatgacctacaggatcgggcaccacagcaccagt
gacgacagctcggcctaccgctcggtggatgaagtcaattactgggacaagcaggaccac
cccatttcccggctgcggcactacttgcagggccgaggctggtgggacgacgagcaggag
aaggcctggagaaagcagtcccgcaggaaggtgatggaggcctttgagcaggcggagcgg
aagccgaagcccaaccccaacctgctcttctcggacgtgtaccaggagatgcccgcccag
cttcgcaagcagcaggagtccctggcccggcacctccagacctacggcgagcactacccc
ctggaccacttcgagaagtga
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