Hyaena hyaena (striped hyena): 120241477 Help Entry 120241477         CDS       T07257                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism hhv  Hyaena hyaena (striped hyena) Pathway hhv04072   Phospholipase D signaling pathway hhv04115   p53 signaling pathway hhv04140   Autophagy - animal hhv04150   mTOR signaling pathway hhv04151   PI3K-Akt signaling pathway hhv04152   AMPK signaling pathway hhv04211   Longevity regulating pathway hhv04218   Cellular senescence hhv04714   Thermogenesis hhv04910   Insulin signaling pathway hhv04919   Thyroid hormone signaling pathway hhv05163   Human cytomegalovirus infection hhv05165   Human papillomavirus infection hhv05168   Herpes simplex virus 1 infection hhv05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:hhv00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     120241477 (TSC2)    04151 PI3K-Akt signaling pathway     120241477 (TSC2)    04152 AMPK signaling pathway     120241477 (TSC2)    04150 mTOR signaling pathway     120241477 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     120241477 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     120241477 (TSC2)    04218 Cellular senescence     120241477 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     120241477 (TSC2)    04919 Thyroid hormone signaling pathway     120241477 (TSC2)   09149 Aging    04211 Longevity regulating pathway     120241477 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     120241477 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     120241477 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     120241477 (TSC2)    05163 Human cytomegalovirus infection     120241477 (TSC2)    05165 Human papillomavirus infection     120241477 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:hhv01009]     120241477 (TSC2) Protein phosphatases and associated proteins [BR:hhv01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      120241477 (TSC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  120241477 NCBI-ProteinID:  XP_039102525 LinkDB All DBs Position Unknown AA seq 1639 aa AA seqDB search MDIGLSSEFLLVLVNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVC YNCLPAESLPLFIVTLCRTVNVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYME DAPLLRGAVFFVGMALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLVK KYRRELQAVTWDILLRILERLLQQLQSLDSPELRAIVHDLLTTVEELCDQNEFHGSHERY FELVERCADQRPESSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLD VLSFVLLINRQFYEEELISSVVISQLSHIPEDRDPQVRKLATQLLVDLAEGCHTHHFNSL LDIVEKVMARSLSAPPELEERDAAAYSASLEDVKTAVLGLLVILQTKLYALPASHAVRVY ETLVSHLQLHYKHGYTLPIASSIRLQAFDFLLLLRADSLHRLGLPSKDGAVRFSPYCVCD SMEPERSSEKKASGPLSPPTGTPGPAPAGPAVRLGSLPYSLLFRVLLQCLKQETDWKVLK LVLSKLPESLRYKVLIFTSPCSVDQLSSALCSMLSGPRTLERLRGTPEGFSRTDLHLAVV PVLTALISYHNYLDKTRQREMVYCLEQGLIYRCASQCVVALAVCSVEMPDIIIKALPVLV VKLTHISATASMAIPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVC LAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSL RIARPPKQGLNNSPPVKEFQESCAADAFRCRSVSVSERVVRSRIQTSLTSASLGSADENS MAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLV TVTTSVGTGTRSLLGLDSGELQGSPELTSDPGVHVRQTKEAPAKLESQAGQQVCRGARDR VRSMSGGHGLRVGALDAPATHVPGAQTAPASTSERASAAAPFPAQEKTSLAAYVPLLTQG WAEILVRRPTGNTSWLMSLENPLSPFSSDIDNMPLQELSNALMAAERFKERRDTALYKSL SVPAAGSVKPPPPPRSNTVASFSSLYQTSCQGELHRSISWADSAVVLEEGSPSDADLPLE PTELEDFEATLGTERHGRRPGAYSRSSSSSSQEEKPFAAEEAAARGLPIERAVSAEGARP SAGLSFQPAQPLSKSSSSPELQTLQDTLGDPADKADVGRLSPEAKARSQSGTLDGAGAAW STPGDESQGRGPARPEGPLPSGCPRSPGGLRPRGYTISDSAPSRRGRRVERDTFKSRAGA SSTEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVL YVGEGQSSSELAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTY CWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNF VHVIITPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHS RSNPTDIYPSKWIARLRHIKRLRHRIREEAHYPNPSLPLTQMHPPGHAKAPAPAEPAPAY ETGQRKRLISSVDDFTEFV NT seq 4920 nt NT seq  +upstreamnt  +downstreamnt atggacatcggcctgtcctcagagttccttctggtgcttgtgaacttggtcaaattcaac agctgttacctggatgaatacattgcgtcaatggtccacatgatctgcctgctgtgcgtc cagactgtgtcctctgtggacatagaggtgtctctccaggtcctggacgccgtcgtctgc tacaactgcctgccggccgagagcctgcccctgttcatcgtcaccctctgccgtaccgtc aacgtcaaggagctctgtgagccctgctggaagctgatgaggaacctcctgggcacccac ctgggccacagtgccatctacaacatgtgccgcatcatggaggacagggcctacatggaa gatgccccgctgctgagaggggccgtgttctttgtgggcatggctctctggggggcgcac cggctctactcgctcaagaactctcccacgtccgtgctgccgtcgttttacgaggccatg acatgtccgaacgaggtggtgtcctatgagatcgtcctgtccatcaccaggctcgtcaag aagtacaggagggagctccaggcggtcacgtgggatatcctgctgcgcatcctcgaacgc ctgctgcagcagctccagagcctggacagcccggagctcagagccattgtccacgacctg ctgaccacagtggaggagctgtgtgatcagaacgagttccatggctcgcacgagagatac ttcgagcttgtcgagaggtgtgcagaccagaggccggagtcgtccctcctaaacttaata acctacagggctcagtcgattcatccggcgaaggatggctggattcacaatctgcagtta ctgatggagagattcttcaggaacgagtcccgcagtgccgtgcgcatcaaggtgctggac gtcctgtccttcgtgctgctcatcaataggcagttctatgaggaggagctgattagctca gtggtcatctcgcagctctcccacatcccagaggacagagacccccaagtccgaaaactg gccacccagttgctggtggacctggccgaaggctgtcacacccaccacttcaacagcctg ctggacatcgtggagaaggtgatggcccgctccctttccgcaccccctgagctggaggaa agggacgcggcggcgtactcggcctccttagaggacgtgaagactgctgtcctggggctg ctggtcatcctgcagactaagctgtacgccttgcctgccagccatgcggtgcgtgtgtac gagacgctcgtcagccacctgcagctccactacaagcacggctacacactgcccatcgcc agtagcatccggctgcaggcctttgacttcctgctgctgctgagggccgactcgctgcac cgcctgggcctccccagcaaggatggggctgtgaggttcagcccctactgcgtctgtgat tccatggagccagagagaagctctgagaagaaggccagcggccccctgtcgcctcccacc gggacgcccggcccagctcctgccggccccgctgtgcggctgggctccttgccctactcc ctgctcttccgagtcctgctgcagtgcttgaagcaggagacggactggaaggtgctgaag ctcgtgctcagcaagctgcccgagtcgctgcgctacaaggtcctcatcttcacctccccg tgcagtgtcgaccagctgtcctctgccctgtgctccatgctttccggccccagaaccctg gagcggctcagagggaccccagaaggcttctcccggaccgacctgcacctggccgtggtt cccgtgctgacggcattaatctcttaccacaactatttggacaaaaccagacagcgggag atggtgtactgcctggagcaaggcctgatctaccgctgcgccagccagtgcgtggtagcc ctggccgtctgcagcgtggagatgccggacatcatcatcaaggcgcttccggtcttggtc gtgaagctcacacacatttcggccacagccagcatggctattccactcctcgaattcctt tcaactctggccaggctgccgcacctctacaggaacttcgcagccgagcagtacgcaagt gtgtttgccatctccctgccgtacaccaatccctccaagtttaatcagtacatcgtttgc ctggcccatcacgtcatagccatgtggttcatcagatgccgcctgcccttccggaaggat tttgttccttatatcactaagggcctgcgctccaatgtcctcctgtcgtttgacgacacc ccggagaaggacagcttcagggcgcggagcaccagtctcaacgagaggcccaagagtttg aggatagccagacccccaaaacaaggcttgaataactccccacccgtgaaagaattccag gagagctgtgcagccgacgccttccggtgccgcagcgtcagtgtgtctgagcgtgtggtc cgcagcaggatccagacgtccctcacaagtgccagcttggggtctgcggatgagaactcg atggcccaggctgacgacaacttgaaaaatctccacctggagctcacggaaacgtgtctg gacatgatggccagatatgtgttctccaacttcacggcggtccccaagaggtccccggtg ggggagttcctcttggctggtggcaggaccaaaacctggctggttgggaacaagctggtc actgtgacgacgagcgtggggaccgggacccggtcactgctgggcttggactccggagag ctgcagggcagcccggagctgacctctgaccccggcgtgcacgtgaggcagacaaaggag gcgcctgccaagctggagtcccaggccgggcagcaggtgtgccgtggggcccgggaccgc gtccgctccatgtccggcggccacggccttcgcgttggtgccctggatgctccggccacc catgtcccaggtgcacagaccgcgccagccagcacgtctgagagggcctcagctgccgcc ccgttcccggcccaggagaagacgagcctggcggcctacgtgcccctgctgacccagggc tgggcggagatcctggtccggaggcccacagggaacaccagctggctgatgagcctggag aacccgctcagcccgttctcctcggacatcgacaacatgcccctgcaggagctgtccaac gccctcatggccgccgagcgcttcaaggagcgtcgcgacacggccctgtacaagtcgctg tcggtgccggcggccggctccgtcaagccccctccgcccccgcgttctaacacagtggcc tctttctcctccctgtaccagaccagttgccaaggagagctgcacaggagcatttcctgg gcagactctgcggtggttctggaggagggaagccccagcgacgctgatttgcccctggag cccaccgagctggaggactttgaggcaacgctgggcaccgagaggcacggccggcgcccc ggagcttacagcaggtcgtcttccagctccagccaagaggagaagccgttcgctgcggaa gaggcagctgcgagagggctccctatcgagcgggccgtgtctgccgagggagcccggccc tccgcggggctctccttccagcccgcccagcccctcagcaagtccagctcctctccggag ctgcagacgctgcaggacacactcggggaccccgcggacaaggccgacgttggccgactg agccccgaggccaaggctcgctcgcagtccgggaccctggacggggcaggcgccgcctgg tcaaccccaggggacgagagccagggccggggccctgcgcggcctgaaggtcccttgcct tctggctgtccccgctctcctggtggcctgcggcccagaggctataccatttctgattca gccccgtcgcgcagaggcaggagggtagagcgggacaccttcaagagcagagctggggcc tccagtactgagaaggtgccaggcatcaaccccagcttcgtgttcctgcagctctaccac tcacctttctttggtgacgagtccaacaaaccgatccttctgcccaatgagtcctttgag cggtcggtgcagctcctcgaccagatcccatcgtacgacacccacaagatcgccgtcctg tacgtgggcgaaggccagagcagcagcgagctcgccatcctgtccaacgagcacggctcc taccggtacacggagttcctgacaggcctgggcaagctcatcgagctcaaggactgccag ccggataaggtgtacctgggcggcctggacgtgtgcggggaggacggccagttcacctac tgctggcatgacgacatcatgcaggccgtcttccacatcgccaccctgatgcccaccaag gacgtggacaagcaccgctgtgacaagaagcgccacctgggcaacgactttgtgtccatt gtctataacgactccggcgaggacttcaagctgggcaccattaaaggccagttcaacttc gtccacgtgatcatcacgcccctggactacgagtgcaacctggtgtcgctgcagtgcagg aaggacatggagggtctcgtggacaccagcgtagccaagatcgtgtctgaccgcaacctg cctttcgtggcccgtcagatggctctgcacgcaaatatggcctcccaggtgcaccacagc cgctcaaaccccacggacatctacccctccaagtggatcgcccggctccgccacattaag cggctccgccaccggatccgtgaggaagcccactacccgaaccccagcctgccgctgacg cagatgcaccccccgggccacgccaaggctccggccccagccgagcctgcgcccgcatat gagacgggccagcgaaagcgcctcatctcttctgtggacgacttcacggagtttgtgtga

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