Hyaena hyaena (striped hyena): 120244482
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Entry
120244482 CDS
T07257
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv04217
Necroptosis
hhv04380
Osteoclast differentiation
hhv04620
Toll-like receptor signaling pathway
hhv04621
NOD-like receptor signaling pathway
hhv04630
JAK-STAT signaling pathway
hhv04658
Th1 and Th2 cell differentiation
hhv04659
Th17 cell differentiation
hhv05145
Toxoplasmosis
hhv05160
Hepatitis C
hhv05161
Hepatitis B
hhv05162
Measles
hhv05164
Influenza A
hhv05165
Human papillomavirus infection
hhv05167
Kaposi sarcoma-associated herpesvirus infection
hhv05168
Herpes simplex virus 1 infection
hhv05169
Epstein-Barr virus infection
hhv05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
120244482 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
120244482 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
120244482 (TYK2)
04621 NOD-like receptor signaling pathway
120244482 (TYK2)
04658 Th1 and Th2 cell differentiation
120244482 (TYK2)
04659 Th17 cell differentiation
120244482 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
120244482 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
120244482 (TYK2)
05160 Hepatitis C
120244482 (TYK2)
05171 Coronavirus disease - COVID-19
120244482 (TYK2)
05164 Influenza A
120244482 (TYK2)
05162 Measles
120244482 (TYK2)
05168 Herpes simplex virus 1 infection
120244482 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
120244482 (TYK2)
05169 Epstein-Barr virus infection
120244482 (TYK2)
05165 Human papillomavirus infection
120244482 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
120244482 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hhv01001
]
120244482 (TYK2)
Enzymes [BR:
hhv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
120244482 (TYK2)
Protein kinases [BR:
hhv01001
]
Non-receptor tyrosine kinases
JAK family [OT]
120244482 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kinase-like
Kdo
FERM_C_FAK1
RIO1
ABC1
Motif
Other DBs
NCBI-GeneID:
120244482
NCBI-ProteinID:
XP_039106972
LinkDB
All DBs
Position
Unknown
AA seq
1194 aa
AA seq
DB search
MACLFPAEPAIKSMPLCRWGVTTRNGRPDGDAQPMATREGLKVLLHWAGPDGGDPWVTFS
EATLTAEEVCIHIARRVGITPSCLNLFALFDAQAQVWLPPNHILEVSRDMNLTLYFRMRF
YFRNWHSMNPQEPAVYRCGPPGAKPSSERAEQGVQLLDPASFEYLFEQGKHEFVNDVAPL
WELTSEEEIHHFKNESLGMAFLHLCHLALCHGIPLEKVARKISFKDCIPRSFRLQIRRHN
ALTRLRLRRLFRRFVRAFQPGHVSQQVIMVKYLATLEQLAPRFGTERVPVCHLEEQAQAA
GGPCYVRDSGQSLLEPGPDLATGPPTHEVLVTGTGGIRWRPVQAEGLRSDDGSSRNPRTG
PSGKKTKAQEGGSPPVGRPQEAPWAYFCDFQDITHVVLKEHLVSIHCQDKCLELTLPSRA
AARSLVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVLAKLRAEDGLY
LIHWSTGHLDRLILTVAQRDQAPGAQHLHLRKFPIELRAGSFVLEGWDRAFPSVRELRAA
LQGCSLRAGDDCFSLRRCCLPRPGELSNLIITRGSRASSSPLNLSQLSFHRVCRDDISQL
SHLGQGTRTNVYEGILRVGGRGPKEGTADGGDPPTPTGDCGQELRVVLKVLDPSHHDIAL
AFYETASLMSQVSHVHLAFVHGVCVHGSENIMVTEYVEHGPVDVWLRRERGHVPVAWKVA
VAQQLASALSYLEDKSLVHGNVCGRNVLLARLGLAEGTSPFIKLSDPGVGLGALSREERV
ERIPWTAPECLSGGANTLTTAADKWGFGATLLEICFDGEAPLQGRGPSEKECFYQKQHQL
PQPSCPELATLTSQCLTYEPAQRPSFRTILRDLTQLQPQNLADVLAVNPDLPASDPTIFH
KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAGGGPQLRTGWRREIDILRT
LYHKHIVKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHNVGLAQLLLFAQQICEGMAY
LHAQHYVHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL
KECKFYYASDVWSFGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGER
LPRPEKCPCEIYILMKNCWEAEASFRPTFQNLIPILKTVQEKYQGQAASVFSVC
NT seq
3585 nt
NT seq
+upstream
nt +downstream
nt
atggcctgtctcttcccagccgagccagccatcaagagcatgcctctgtgccgttggggt
gtcaccaccaggaacggcaggcctgatggggatgctcagcccatggccacccgggaaggc
ctgaaggtccttctgcactgggctggccctgacggcggggacccctgggtcaccttcagc
gaggccacactgaccgcagaggaggtctgcatccacatcgcacgcagagtcggcatcact
ccctcctgcctcaatctcttcgccctctttgatgcccaggcccaggtgtggctgccccca
aaccacatcttggaggtctccagagacatgaacctgacactgtacttccgcatgaggttt
tatttccggaactggcacagcatgaacccacaggagccagccgtgtaccgctgcgggccc
cccggggccaagccttcctccgaacgggcagagcagggggtgcaactcctggacccagcc
tcctttgagtacctctttgagcagggcaagcatgagtttgtgaatgacgtggcacccctg
tgggagctgaccagcgaggaagagatccaccattttaagaacgagagcctgggcatggcc
ttcctgcacctttgccacctcgccctttgccatggcatccccctggagaaggtggccagg
aagatcagcttcaaggactgcatcccgcgctccttccggctgcagatccggcggcacaac
gcgttaacacggctgcgcctgcggagactgttccgcaggtttgtgcgggccttccagccg
ggccacgtctcccagcaggtcatcatggtcaagtacctggccacactcgagcagctggca
ccccgcttcggcacggagcgcgtgcctgtgtgccacctggaggagcaggcccaggccgcg
ggggggccctgctatgtccgggacagtggccagtccctcctggagccagggcctgacttg
gccaccggaccccccacacatgaggtgctggtgacaggcactggcggcatccggtggcgg
ccagtacaggcagagggtctccgcagcgacgacggtagcagcaggaacccccgcactggc
ccatcagggaagaaaaccaaggcccaggaggggggcagccccccggtgggcaggcctcag
gaagcgccctgggcctacttctgtgacttccaggacatcacccacgtggtgctgaaagag
cacctagtcagcatccactgtcaggacaagtgcctggagctcaccctgccttcccgggct
gcggcccggtccttggtgtcgctggtggacggctacttccgcctaacggccgactcaagc
cactacctgtgccatgaggtggcgcctccgcggctggtgatgagcatccgggatggcatc
cacgggcccctgctggagcccttcgtgttggccaagctgcgggccgaggatggcctctac
ctcatccactggagcaccgggcaccttgaccgcctcatcctcacggtggctcagcgcgac
caggcacctggtgctcagcacctgcacctgcggaaattccccattgagctgcgggccggg
agcttcgtgctggagggctgggaccgcgccttccccagcgtgcgggagctacgcgccgcc
ctgcagggctgctcgctgcgggccggggacgactgtttctccctgcgccgctgctgcctg
ccgcggcccggagagctctccaacctcatcatcacgcgcgggtctcgggccagctccagc
ccactcaacctcagccagctcagcttccaccgcgtctgccgggatgacatcagccagctg
tcccacttgggccaaggcacaaggaccaatgtgtatgagggcatcttacgagtgggggga
agaggccccaaggagggcacggccgatggcggggacccccccacacccactggggactgt
gggcaggagctgcgagtggtactcaaggtgctggaccccagtcaccacgacatcgccctg
gccttctacgagacagccagcctcatgagccaggtctcccacgtgcacctggcctttgtg
catggcgtctgcgtgcatggctctgagaacatcatggtgacagagtacgtggagcacggg
cccgtggacgtgtggctgcggcgggagaggggccacgtgcctgtggcctggaaggtggcc
gtggcccagcagctggccagcgccctcagctacctggaagacaagagcctggtccatggt
aacgtgtgtggccggaacgtcctgctggcccggctgggactggcggagggcaccagcccc
ttcatcaagctgagcgaccccggtgtgggcctgggtgccctttccagggaggagcgggta
gagcggatcccctggacagcccccgagtgcctctctggcggggccaacaccctaaccacc
gcagccgacaaatggggttttggtgccaccctcctggagatctgcttcgacggggaggcc
ccgctacagggccgcggcccctccgagaaagagtgcttctaccagaagcagcaccagctt
cctcaaccctcatgcccggagctggccacactcaccagccagtgcctgacctatgaacca
gcccagcggccctccttccgcaccatcctgcgtgacctcactcagctgcagccccagaat
cttgctgacgtcttggccgtgaaccccgacttgcctgcgtctgaccccaccattttccac
aagcgctatttgaaaaagatccgggatctgggcgagggtcatttcggcaaggtcagtctg
tattgctacgacccgactaacgatggcaccggcgagatggtggctgtgaaggcgctcaag
gcgggcgggggcccccagctccgcaccggctggaggcgggagatcgacatcctgcgcacg
ctctaccacaagcacatcgtcaaatacaagggctgctgtgaggaccaaggagagaagtcg
gtgcagcttgtcatggagtacgtgcctctgggcagcctccgggactaccttccccggcac
aacgtcggactggcgcagctgctgctcttcgcccagcagatctgtgagggcatggcctac
cttcacgcacagcactacgtccaccgagacctggctgcccgcaacgtgctgctagacaac
gacaggctggtcaaaatcggagactttggcctagccaaggctgtgcccgaaggccatgag
tactaccgtgtgcgcgaagatggggacagccccgtattctggtatgcgccggagtgcctg
aaggagtgtaagttctactatgcatctgacgtctggtccttcggggtcaccatgtatgag
ctcctgacctactgtgactccagccagagccccccttcgaaattcatcgagctcataggc
ctcacccaagggcagatgacagtgctgaggctcactgagctgctggagcgaggggagagg
ctgccacggccagagaaatgtccttgcgagatctatatcctcatgaagaactgctgggaa
gcagaggcctcattccgccccaccttccagaacctcatacccattctcaagacggtccag
gagaaataccagggccaggccgcctcggtgttcagtgtgtgctga
DBGET
integrated database retrieval system
