Hyaena hyaena (striped hyena): 120245065
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Entry
120245065 CDS
T07257
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
120245065 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
hhv03032
]
120245065 (TOP2B)
03036 Chromosome and associated proteins [BR:
hhv03036
]
120245065 (TOP2B)
Enzymes [BR:
hhv01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
120245065 (TOP2B)
DNA replication proteins [BR:
hhv03032
]
Eukaryotic type
DNA Topoisomerases
120245065 (TOP2B)
Chromosome and associated proteins [BR:
hhv03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
120245065 (TOP2B)
Centrosome formation proteins
Centriole proteins
120245065 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
120245065
NCBI-ProteinID:
XP_039107864
LinkDB
All DBs
Position
Unknown
AA seq
1619 aa
AA seq
DB search
MAKAGGGAGAGGNGALTWVTLFDQNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHI
LLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMT
CIKVSIDPESNIISIWNNGKGIPVVEHKVEKVFVPALIFGQLLTSSNYDDDEKKVTGGRN
GYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDL
SKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETG
VALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKK
KNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAAS
NCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGD
SAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYD
DAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKN
KQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGP
EDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKEL
ILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQA
LMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLSRLLFPAVDD
NLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGL
DPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPM
LNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLF
DHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKI
TIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPDFN
YILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQER
EDILAGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASKKLLKRKKGD
LDTTAVKVEFDEEFSGTPVEGTGEEVLIPSAPVNKGPKPKREKKEPGTRVRKTPTSSGKS
TAKKVKKRNPWSDDDSKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADD
DEDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSSHDKKGQDFG
NLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTTA
KPKRTPKQKKVETINSDSDSEFGIPKKTTPPKGKGRGAKKRKASGSENEGDYNPGRKTSK
PPSKKLKKTSFDQDSDVDIFPSDFTSEAPSLPRSGRARKEVKYFAESDDEEDVDFAMFN
NT seq
4860 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcgcgggagccggcggcaacggggcgctgacctgggtgact
ctttttgatcagaacaatgctgcaaaaaaagaagagtcagaaactgcaaacaaaaatgat
tcttcaaagaagttgtctgtagagagagtgtatcagaaaaagacgcaacttgaacatatt
ctccttcgtcctgatacgtatattgggtcagtggagccattgacacagctaatgtgggta
tatgatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggtttatacaag
atctttgatgaaattttggttaatgcagctgacaataaacagagggataagaatatgacc
tgtattaaagtttctattgatcctgaatctaacattatcagcatttggaataatgggaaa
ggcattccagtagtagaacacaaagtagagaaagtttttgttcctgcattaatttttgga
cagcttttaacatccagtaactatgatgatgatgagaaaaaagtaacaggtggtcgcaat
ggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaaccgcttgc
aaagaatacaaacatagttttaagcagacctggatgaataacatgatgaaaacttctgaa
gccaaaattaaacattttgatggtgaagattacacatgcataacattccaaccagatttg
tctaaatttaagatggaaaaacttgacaaggatattgtggccctcatgaccagaagagct
tatgatttggctggttcatgcaaaggggtcaaggtcatgtttaatggaaagaaattgcct
gtaaatggatttcgcagttatgtagatctttatgtgaaagacaagttggatgaaactgga
gtggccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctcacattg
agtgaaaagggattccagcaaatcagctttgtaaatagtattgcaacaacaaaaggtgga
cgtcacgtggattacgtagtagatcaagttgttggtaagctgattgaagtagttaagaaa
aagaacaaagctggtgtatcagtaaaaccatttcaagtaaaaaatcatatatgggttttt
attaattgccttatcgaaaatccaacttttgattctcagactaaggaaaacatgactcta
cagcccaaaagttttgggtcaaaatgccagctgtcagaaaaattttttaaagcagcctct
aactgtggcattgtagaaagtattctgaactgggtgaaatttaaagctcagactcagctg
aacaagaagtgttcatcagtaaagtatagtaaaatcaaaggtattcccaaactggatgat
gctaatgatgctggtggcaaacattccctggagtgtacattgatactaacagagggagac
tctgccaaatcgctggctgtgtcgggattaggtgtgattgggcgagacagatacggagtc
tttccacttaggggaaaaattcttaacgtccgagaagcttcgcataaacagatcatggaa
aatgcagaaataaacaatattatcaaaatagttggtctacaatacaagaaaagttatgat
gatgcagaatccctgaaaactttacgctatggaaaaattatgattatgactgatcaggat
caagacggttctcacataaaaggcctgcttattaatttcatccatcataattggccatca
cttttgaagcatggttttcttgaagagttcattactcctattgtgaaggctagcaaaaat
aagcaggaactttccttctatagtattcctgaatttgatgagtggaaaaaacatatagaa
aaccagaaagcctggaaaataaagtactacaaagggttgggtaccagtacagctaaagaa
gcaaaggagtattttgctgatatggaaaggcaccgcatcttgtttagatatgctggccct
gaagatgatgctgccattaccttggcattcagtaagaagaagattgatgacagaaaagaa
tggttaacaaattttatggaagaccggagacagcgtaggttgcatggcttaccagagcaa
tttttgtatggtacagcaacaaagcatttgacttataatgatttcatcaataaggaattg
attctcttctcaaactcagacaatgaaagatctataccatctcttgttgatggctttaag
ccaggccaacgtaaagttttatttacctgtttcaagaggaatgataagcgtgaagtgaaa
gttgcccagttggctggatctgttgctgagatgtctgcttaccatcatggagaacaagca
ttgatgatgactattgtgaatttggctcagaactttgtgggaagtaacaacattaacttg
cttcagccaattggtcagtttggaactcggcttcatggtggtaaagatgctgcaagccct
cgttatattttcacaatgttaagctctttatcaagactgctttttcctgctgtggatgac
aacctgcttaaattcctttatgatgataatcaacgtgtagagcctgagtggtatattcca
ataattcccatggttttaataaatggtgctgagggcattggtactggatgggcttgtaaa
ctacccaactatgatgctagggaaattgtgaataacgtcagacgaatgctagatggcttg
gatcctcatcctatgcttccaaactacaaaaactttaaaggaacgatccaggagctcggt
caaaaccaatatgccgtcagtggtgaaatatttgtggtggatagaaacacagtagagatt
acagagcttcccgttagaacttggacacaggtatacaaagaacaggttttggaacctatg
ctaaatggaacagataaaacaccagcattaatttctgattataaagaatatcatactgat
acaactgtgaaatttgtggtgaaaatgactgaagagaagcttgcacaagcagaagctgct
ggattgcataaagtttttaaacttcaaactactcttacttgtaattccatggtactcttt
gatcatatgggatgtctcaagaagtatgaaactgtgcaagacattttgaaagaattcttt
gatttacgattaagttattatggtttacgtaaggagtggcttgtaggaatgttgggagca
gaatctacaaagcttaataatcaagcccgtttcattttagagaagatacagggaaaaatt
accatagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttatgaa
tctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcggaagaggaagaaacg
caaaaccagcatgatgatagttcctctgattcaggaactccttcaggccccgattttaat
tatattttaaatatgtccctgtggtctcttactaaagaaaaagttgaagaactgattaaa
cagagagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatctccttcagatctt
tggaaagaagatttagcagcatttgttgaagaactggataaagtagaagcgcaagaacga
gaagatattctggctggaatggctgggaaagccataaaaggtaaagttggcaaacctaag
gtgaagaaacttcagttggaagagacaatgccttccccttatgggagaagaatagttcct
gaaattactgctatgaaggcagatgccagcaaaaagttgctgaagaggaaaaagggtgat
cttgataccacagcagtaaaagtagaatttgatgaagaattcagtggaacgccagtagag
ggtacaggagaagaggtattgatcccatcagctcctgtaaataaaggtcctaaacccaaa
agggagaaaaaggaacctggtaccagggtgagaaaaacacctacatcatctggtaaatcc
actgcaaagaaagtgaagaagcggaatccttggtcagatgatgattccaagtcagaaagt
gacttggaagaaacagagcctgtggttattcccagagattctttgcttaggagagcagct
gctgaaaggcctaagtacacatttgacttctcagaagaggaggatgatgatgctgatgat
gatgaagacaataatgatttagaggaattgaaagtgaaagcatctcccataacaaatgat
ggggaagatgaattcgttccttcagatggcctagataaagatgaatatacattttcacct
ggcaaatcaaaagctactccagaaaaatcttcacatgacaaaaaaggtcaagactttggg
aatctgttctcatttccttcatactctcagaagtcagaagatgattctgctaaatttgac
agtaatgaagaagattctgcctctgtcttttcaccatcgtttggtctaaaacaaacagat
aaagttccaagtaaaacagtagctgctaaaaagggaaaaccatcttcagatacaactgct
aagcccaagagaacccctaaacagaagaaagtagagacgataaactctgactcagattca
gaatttggcattccaaagaagactacacccccaaaaggtaaaggccgaggagcaaagaaa
aggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaaacctccaaa
ccaccaagcaagaaactgaagaaaacctcttttgatcaggattcagatgtggacatcttc
ccatcagacttcacttctgaagcaccttctctgccccggagcggtcgggctaggaaagaa
gtaaaatattttgcagagtccgatgatgaagaagatgttgattttgcaatgtttaattaa
DBGET
integrated database retrieval system
