Hyaena hyaena (striped hyena): 120245671 Help Entry 120245671         CDS       T07257                                  Symbol NF1 Name (RefSeq) neurofibromin isoform X1   KO K08052   neurofibromin 1 Organism hhv  Hyaena hyaena (striped hyena) Pathway hhv01521   EGFR tyrosine kinase inhibitor resistance hhv04010   MAPK signaling pathway hhv04014   Ras signaling pathway Brite KEGG Orthology (KO) [BR:hhv00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     120245671 (NF1)    04014 Ras signaling pathway     120245671 (NF1)  09160 Human Diseases   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     120245671 (NF1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PH_NF1 RasGAP CRAL_TRIO_2 CRAL_TRIO MIF4G_like_2 Motif Other DBs NCBI-GeneID:  120245671 NCBI-ProteinID:  XP_039108751 LinkDB All DBs Position Unknown AA seq 2841 aa AA seqDB search MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL QYINVDCAKLKRLLKETAFKFKSLKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLVLCPEIIQDISKDVVDENNMNKKLFL DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK PTDVETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL REILICRNKFLLKNKQADRSSCHFLFLYGVGCDVPSSGATSQMSMDHEELMRTCTPGASL RKGKGNSSVESAAGCGSAPPICRQAHTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEAD IRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWE DTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWI NMTGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRL LSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNT QFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQL VEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVS LLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRL ASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAE TVLADRFERLVELVTMMGDQGELPIAMALASVVPCSQWDELARVLVTLFDSRHLLYQLLW NMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSEWQHVS FEVDPTRLEQSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLN KATAKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERG LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDTVNHSLSF ISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTH WSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQI NGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVY IYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLK VFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQ FTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIA LLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAAN EPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKL ITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVAL ASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAA HLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSL PKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMR DIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESC LKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVSLYSAGSALL EQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGY RHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHR KSLLLTDISMENVPMDTYPIHHGDPNYRTLKENQPWSSPKGSEGYLAATYPTVGQTSPRA RKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYE METQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRI LYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQY QTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTP TSPYPPAVQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPASGHCSSGRTRHGSA SQVQKQRSAGSFKRNSIKKIV NT seq 8526 nt NT seq  +upstreamnt  +downstreamnt atggccgcgcacaggccggtggaatgggtccaggccgtggtcagccgcttcgacgagcag cttccaataaaaacaggacagcagaacacgcataccaaagtcagtactgaacacaacaag gaatgtcttattaatatttccaaatacaagttttctttggttatcagcggcctcaccact atcttaaagaatgttaacaatatgagaatatttggagaagccgccgaaaaaaatttatat ctctctcagttgattatattggatacactggaaaaatgtcttgctgggcaaccaaaggac acaatgagattagatgaaacgatgctggtcaaacagttgctgccagaaatctgccatttt cttcacacctgtcgtgaaggaaaccagcatgcagctgaacttcggaattctgcgtctggg gttttgttttctctcagttgcaacaacttcaatgcggtgtttagtcgcatttctaccagg ttacaagaattgactgtttgttctgaagacaatgttgacgttcatgatatagaattgtta cagtatatcaatgtggattgcgcaaaattaaaacgactcctaaaggaaacagcatttaaa tttaaatccctaaagaaggttgcacagttagcagttataaatagcctggaaaaagcattt tggaactgggtagaaaattatccagatgagtttacgaagctgtaccagattccacagaca gatatggctgagtgtgcagagaaactgtttgacctggtggatggttttgccgaaagcacc aaacgtaaagcagcagtttggccgctgcagatcattctccttgtcttgtgcccagagata atccaggatatatcgaaggatgtggttgatgaaaacaacatgaataagaagttgtttctg gacagcctacggaaagcactcgctggccacggaggaagcaggcagctgaccgagagtgct gcgatcgcctgtgtgaaactgtgcaaggccagtacttacatcaactgggaggacaactct gtcatcttcctactagtccagtccatggtggtggatcttaagaacctgctttttaatcca agtaagccattctcaagaggcagtcagcccgcagatgtggatctcatgattgactgcctt gtttcttgctttcgtataagtcctcacaacaaccaacactttaagatctgcctggctcag aattccccttctacatttcactacgtgctggtaaattcactccatcgaatcatcaccaat tctgcgttggattggtggcctaagattgatgctgtgtactgtcactcagtcgagcttcga aacatgtttggtgaaacgcttcataaagcggtgcagggctgtggagcccacccggcaata cgaatggccccgagtcttacgtttaaagaaaaagtaacaagccttaaatttaaagaaaaa cctacagacgtggagacaagaagctataagtatcttctcctgtccatggtgaaactcatt catgcggatccaaagctcttgctttgtaaccccaggaagcaggggcctgagacccagggc agcacagcggagttaattacagggcttgtgcagctggtccctcagtcacacatgcccgag atcgctcaggaggcaatggaggccctgctcgttcttcatcagttagatagcattgatttg tggaatcctgatgctcctgtggaaacgttttgggaaattagctctcaaatgcttttttac atctgcaagaaattaactagccatcaaatgcttagtagcacagaaatcctcaaatggttg cgggaaattttgatctgcaggaataaatttcttcttaaaaataagcaggcagatagaagt tcctgtcactttctcttcctttatggggtaggctgtgacgttccttcaagtggagccacc agtcagatgtccatggatcatgaagaattaatgcgcacctgcactcccggagcctctctt cggaagggaaaaggaaactcgtccgtggagagcgcggcagggtgcggcagcgccccaccc atatgccggcaggcgcacaccaaactggaagtggccctgtacatgtttctgtggagccct gacaccgaagccgtcctggtggccatgtcctgtttccgccacctctgtgaggaagcagac atccgctgtggggtggatgaagtgtcggtgcacaacttcctgcccaactataacacgttc atggagtttgcctctgtcagcaatatgatgtcaacaggaagagcagcgcttcagaagaga gtgatggcactactcaggcgcatcgagcaccccactgcagggaacacggaggcttgggaa gatacacatgcaaagtgggaacaagccacgaaactaatcctcaactatccaaaagcgaaa atggaagatggccaggcagcagaaagccttcacaagaccattgttaagaggcgaatgtct cacgtgagtggaggaggatccatagatttgtctgacacggactccctgcaggagtggatc aacatgaccggcttcctgtgtgcccttgggggagtgtgcctgcagcagagaagcaactct ggcttggcaacctacagcccgcccatgggcccagtcagcgaacgcaagggctccatgatt tccgtgatgtcctcggagggaaatgcagatacacctgtcagcaaattcatggaccggctc ttatccttaatggtgtgtaaccatgagaaagtgggacttcagatacggaccaacgttaag gatctggtgggcctagaattgagtcctgctctttatccaatgctgtttaacaaactgaag aacactatcagcaagttctttgactcccagggacaggttttattgactgacaccaacact cagtttgtggagcaaaccatagctatcatgaagaacttactagataatcatactgaaggc agctctgaacatctggggcaagctagcattgaaacaatgatgttaaatctagtcagatat gttcgagtgcttgggaacatggtccatgcaattcaaatcaaaacaaaactgtgtcagttg gtcgaggtaatgatggcaaggagagatgacctctcgttttgtcaagagatgaaatttagg aataagatggtagaatacctgacagactgggtcatgggaacatcaaaccaggcagcagat gatgatgtaaagtgtcttacaagagacttggaccaggcgagtatggaagcagtcgtgtca ctcctggccggccttccgctgcagcccgaggaaggagacggcgtggaattgatggaagcc aaatcacagttatttcttaagtatttcacgttgtttatgaaccttttgaacgactgtagt gaagttgaagatgaaaatgcacaaacaggcggcaggaaacgtggcatgtctcggaggctg gcatcactgaggcactgtaccgtacttgcaatgtccaacctactcaatgcgaatgtggac agtggcctcatgcactccataggtttaggttatcacaaagatcttcagacaagagccaca tttatggaagttctgaccaaaatcctccagcagggcacagaatttgacacacttgcagaa acggtgctggccgaccggtttgagaggctggtagagctggtgacgatgatgggggaccag ggggagctgccgatagccatggctctggccagcgtggtcccgtgttctcagtgggatgaa ctagctcgagttctagtcactctgtttgattctcgccatttgctctaccaactgctctgg aacatgttttctaaggaggtagaattggcagactccatgcagactcttttccggggaaac agcttagccagtaaaatcatgaccttctgtttcaaggtatatggtgctacctacctacag aaactcctggatccgttattacgaatcgtaatcacatcctctgagtggcagcacgttagc tttgaagtggatcccaccaggttagaacagtcagagagccttgaggaaaaccagcggaac cttcttcagatgactgaaaagttcttccatgccatcattagttcctcctcagaattcccc cctcagcttcgaagtgtatgccactgtttataccaggcaacttgccactccctactgaat aaagctacagcaaaagaaaaaaaggaaaacaaaaaatccgttgttagccagcgtttccct cagaacagcatcggtgcggtgggaagtgccatgttcctcagatttatcaatcctgccatt gtctcaccgtatgaagcagggattttagataaaaagccgccacctagaattgaaaggggc ttgaagttaatgtcaaagatacttcagagcattgccaatcatgttctcttcacaaaagaa gagcatatgcggccttttaatgattttgtgaaaagcaactttgatgcagcacggaggttt ttccttgatatagcatcggactgtcctacaagtgacacagtgaaccatagcctctccttc atcagcgatggcaatgtgctcgctttacatcgtctcctctggaacaatcaagagaaaatt ggccagtatctttccagcaacagggatcacaaagctgttggaagacgaccttttgataag atggcaacacttcttgcctacctgggtcctccggagcacaaacccgtggccgacacacac tggtccagccttaaccttaccagttcaaagtttgaggaatttatgactaggcatcaagta catgaaaaagaagagttcaaggctttgaaaacattaagtattttctaccaagctgggact tccaaagctgggaatcctatattttattatgtggcacggaggtttaaaactggtcagatc aatggtgatttgctgatttaccacgtcttgctgaccttaaagccatattatgcaaagcca tatgaaatcgtagtggaccttactcacaccgggcctagcaatcgctttaaaacggacttc ctctccaagtggtttgttgtgtttcctggctttgcttacgacaacgtctctgcagtctac atctataactgtaactcctgggtcagggagtacaccaagtaccacgagcggctgctcacg ggcctcaaaggcagcaagaggctcattttcatagactgtcctgggaagctggctgagcac atagagcacgagcaacagaagctccccgctgccacactggccttagaagaggacctgaag gtgttccacaatgctctcaagctggcgcacaaagacaccaaggtctctattaaagttggt tctactgctgttcaagtaacctcagcagagcgaacaaaggtcctggggcagtcggtcttt ctgaatgacatctattacgcttcagaaattgaggagatctgcctggtggacgagaaccag tttaccttaaccattgcaaaccagggcaccccgctcaccttcatgcaccaggagtgcgaa gccatcgtccagtccatcattcacatccggacgcgctgggagctgtcgcagcccgactcc atcccccagcacaccaagattcggcccaaagatgtccctgggacactgctcaatattgca ttacttaatttaggcagctcggaccctagtttacggtcagctgcctataatcttctctgt gccttaacttgtacctttaatttgaaaatcgagggccagttactagagacgtcaggttta tgcatccctgccaacaacaccctctttattgtctctattagtaagaccctggcagccaac gagccacatctcaccttagaatttttggaagagtgtatttctggatttagcaaatctagt attgaactgaaacatctctgtttggaatacatgactccctggctgtccaacctcgtccgt ttttgtaagcacaatgatgatgccaaacgacaaagagttaccgccattctcgataagctc ataacaatgaccataaatgagaaacagatgtacccatctattcaagccaaaatctggggg agccttgggcagattacagatctccttgacgtcgttctagacagtttcatcaaaaccagt gcaacaggtggcttgggatcaataaaagccgaggtgatggcagatactgctgtagctttg gcttctggaaatgtgaaattggtttcaagcaaggttattggaaggatgtgcaaaataatt gacaagacgtgcttgtctccaactcccaccttagaacaacatctcatgtgggacgatatc gccatcctagcacgctacatgctgatgctgtccttcaacaattcccttgatgtggccgct catctcccctacctcttccacgtcgtcactttcttagtagccacggggccactctccctc agagcttccacgcacggactggtcattaatatcattcactccctgtgtacttgctcacag ctgcattttagtgaagagaccaagcaagttttgagactcagcttgacagagttctcctta cccaagttttacttgctgtttggcattagcaaagtcaagtcggccgccgtcatcgccttc cgctcgagttaccgggacaggtcgttctctcccggctcctatgagagggagacatttgct ttgacctccttggaaacagtcacagaagctttgttggagatcatggaggcatgcatgaga gatattccaacttgcaagtggctggaccagtggacagaactagctcagagattcgcattc caatataatccgtccctgcaacctcgagctcttgttgtctttggctgtattagcaagcgt gtgtctcacgggcagataaagcagattatccgtattcttagcaaggcacttgagagttgc ttaaaaggacctgatacttacaacagtcaagttctgatagaagccacagtaatagcgcta accaaattacagccactcctcaataaggactcccctctgcacaaagccctcttctgggtg gcggtggccgtgctccagctcgacgaggtgagcttgtactcagcaggctccgcactcctg gagcagaacctgcacaccttagacagtctgcgcatattcaacgacaagagtccggaggaa gtatttatggccatccggaatcctctggaatggcactgcaagcagatggaccattttgtt ggactcaacttcaactctaactttaacttcgcgctggttggacacctcttaaaaggctac aggcatccttcgcctgccatcgttgcaagaacggtcagaattctgcacacactactgact ctggttaacaaacacagaaactgtgacaagtttgaggtgaacacacagagcgtggcttac ttagcagccttactcacagtgtctgaggaggttcgaagtcgctgcagcctaaaacataga aagtctcttcttcttactgatatttcaatggaaaatgttcctatggatacatatcccatc caccatggcgaccccaactataggacactaaaggagaaccagccgtggtcgtctcccaaa ggttctgaaggctaccttgccgccacctatcctaccgtgggccagaccagtccccgggcc aggaaatccatgagtttggacatggggcagccttctcaggccaatacgaagaagttgctg ggaacaaggaaaagttttgatcacttgatatcagacacaaaggctcctaaaaggcaagaa atggaatcagggatcacaacaccccccaaaatgaggagagtagcagaaactgattatgaa atggagactcagaggatttcctcgtcgcagcaacacccgcatttacgtaaagtctcggtg tctgaatcaaatgttctcttggatgaagaagtacttactgatccgaagatccaagcgctc cttcttaccgttctggctacgctggtaaaatataccacagatgaatttgatcagcgaatt ctttatgaatacttagcggaagccagtgtggttttccccaaagtttttcccgtcgtacac aatttgttggactctaagatcaacacgctgttgtcattgtgccaagatccaaatctgtta aatccaattcatggaattgtgcagagtgtggtgtaccatgaagagtccccaccgcagtac cagacctcttacctgcaaagttttggttttaatggcttgtggcggtttgcaggacccttt tcaaagcaaacccaaatcccagactatgctgagcttattgttaagtttcttgatgccttg attgacacgtatttgcctggaattgatgaagaaaccagtgaggagtccctcctgacaccc acttctccttatcctcctgcagtgcagagccagctcagtatcactgctaaccttaacctt tctaattccatgacctcactcgccacttcccagcattccccagggatcgacaaggagaat gtcgaactctcccccgcctctggccactgtagcagtggacgcactcgccacgggtccgcg agccaggtgcagaagcaaagaagcgctggcagtttcaaacggaatagcatcaagaagatc gtgtga

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