Hyaena hyaena (striped hyena): 120246360
Help
Entry
120246360 CDS
T07257
Symbol
NOS2
Name
(RefSeq) nitric oxide synthase, inducible isoform X1
KO
K13241
nitric-oxide synthase, inducible [EC:
1.14.13.39
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv00220
Arginine biosynthesis
hhv00330
Arginine and proline metabolism
hhv01100
Metabolic pathways
hhv04020
Calcium signaling pathway
hhv04066
HIF-1 signaling pathway
hhv04146
Peroxisome
hhv04371
Apelin signaling pathway
hhv04926
Relaxin signaling pathway
hhv05010
Alzheimer disease
hhv05014
Amyotrophic lateral sclerosis
hhv05022
Pathways of neurodegeneration - multiple diseases
hhv05133
Pertussis
hhv05140
Leishmaniasis
hhv05142
Chagas disease
hhv05145
Toxoplasmosis
hhv05146
Amoebiasis
hhv05152
Tuberculosis
hhv05200
Pathways in cancer
hhv05222
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
120246360 (NOS2)
00330 Arginine and proline metabolism
120246360 (NOS2)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
120246360 (NOS2)
04066 HIF-1 signaling pathway
120246360 (NOS2)
04020 Calcium signaling pathway
120246360 (NOS2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
120246360 (NOS2)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
120246360 (NOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
120246360 (NOS2)
09162 Cancer: specific types
05222 Small cell lung cancer
120246360 (NOS2)
09171 Infectious disease: bacterial
05133 Pertussis
120246360 (NOS2)
05152 Tuberculosis
120246360 (NOS2)
09174 Infectious disease: parasitic
05146 Amoebiasis
120246360 (NOS2)
05145 Toxoplasmosis
120246360 (NOS2)
05140 Leishmaniasis
120246360 (NOS2)
05142 Chagas disease
120246360 (NOS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
120246360 (NOS2)
05014 Amyotrophic lateral sclerosis
120246360 (NOS2)
05022 Pathways of neurodegeneration - multiple diseases
120246360 (NOS2)
Enzymes [BR:
hhv01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
120246360 (NOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
120246360
NCBI-ProteinID:
XP_039109764
LinkDB
All DBs
Position
Unknown
AA seq
1164 aa
AA seq
DB search
MACPWQFLFKAKAHQSNLTEETDINNNVGKAARAPSSLVTQDDSKCHSLSKHRNEPPQAL
TGTVKTVPEFLGKLDVPPSACPRHVRIKNWGSGMTFQDTLHHKAKGDLACRSKSCLGAIM
NPKSLTRGPRDKPTPPDELLPQAIEFVNQYYSSFKEAKIEEHLARVEAVTKEIETTGTYQ
LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFDHICRHVRYATNNGNI
RSAITVFPQRSDGKHDFRIWNAQLIRYAGYQMPDGTVIGDPASVEFTQLCIDLGWKPKYG
RFDVVPLVLQADGRDPELFEIPPDLVLEVPMEHPKHEWFRELGLKWYALPAVANMLLEVG
GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNVLEEVGRRMGLETHKLASLWKDRAVVEINV
AVLHSFQKQNVTIMDHHSAAESFMKYMQSEYRSRGGCPADWIWLVPPISGSITPVFHQEM
LNYVLSPFFYYQVEAWKTHVWQDETRRPRRRKVPFRVLVKAVLFASMLMRKTMASRVQAT
ILFATETGKSETLARDLGALFSCAFNPKVLCMDQYRLSNLEEEQLLLVVTSTFGNGDSPS
NGEKLKKSLFMLKELTNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGATQLAPTGEGD
ELSGQEEAFRGWAVQTFKAACETFDVRGKHLIQIPKLYTSNVTWDPHRYRLVQDSQPLDL
NKALSSMHAKNVFTMRLKSQQNLQSPQSSRATLLVVLSCEDGHRLSYVPGEHLGVFPGNQ
LALVRGILERVVDGPAPHQPVCLETLSESGSYWVRDKRLPPCSLSQALTYFLDITTPPTQ
LLLRKLAQLATEEAERQRLETLCQPSEYNKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQL
PILKPRYYSISSCRARTPTEVHLTVAVLTYRTRDGQGPLHHGVCSTWLSGLKPQDPVPCF
VRSVGGFQLPEDPSQPCILIGPGTGIAPFRSFWQQRLHDAEHKGLRGGRMTLVFGCRRPE
EDHLYREEMLEMAQKGVLHAVHTAYSRLPGQPKVYVQDVLRQRLASEVLRVLHEEQGHLY
VCGDVRMARDVALTLKHLLAAKLSLSEEQVEDYFFQLKSQKRYHEDIFGAVFPYEVKTDG
ATRQPSNPQVPAAHGPRDSCCHGT
NT seq
3495 nt
NT seq
+upstream
nt +downstream
nt
atggcctgtccctggcagtttctgttcaaggccaaagcccaccagtccaacttgactgag
gaaacagacatcaacaacaatgtggggaaagccgcccgggccccctccagtctagtgaca
caggatgactccaagtgtcacagcctcagcaagcaccggaatgagcccccccaggccctc
acggggacagtgaagacggttccagaattcctggggaagctggatgtgcccccatcggcc
tgcccacggcacgtgaggatcaaaaactggggcagtgggatgaccttccaagatacactt
caccacaaggccaaaggggaccttgcttgcaggtccaagtcatgtctgggagccatcatg
aaccccaaaagtttgaccagaggacccagggacaagcctacccccccagacgagcttcta
cctcaagccatcgaatttgtcaaccagtattacagctctttcaaagaggcaaaaatagag
gaacatctggccagggtggaagcggtaacaaaggagatagaaacaacaggaacctatcag
ctgacgggagatgagctcatcttcgccaccaagcaggcctggcgcaacgccccccgctgc
atcgggcggatccagtggtccaacctacaggtcttcgacgcccggagctgttccactgcc
caggagatgttcgatcacatctgtagacacgtgcgttatgctaccaacaatggcaatatc
aggtcggccatcaccgtgttcccccagcgcagcgatggcaagcatgacttccggatctgg
aacgcccagctcatccgctatgctggctaccagatgcccgatggcacagtcattggggac
cctgccagcgtggagttcacccagctgtgcatcgacctgggctggaagcccaagtatggc
cgcttcgacgtagtgcctctggtcctgcaggctgacggccgagaccccgagctcttcgaa
atcccgcctgaccttgtgctcgaggtgcccatggaacatcccaagcatgagtggttccgt
gagctggggctcaagtggtacgccctgcccgccgtggccaacatgctgctcgaggtgggt
ggcctggagttcccagggtgcccgttcaacggctggtacatgggcacggagatcggggtc
cgggacttctgtgacgttcagcgctacaacgtgctggaggaagtgggcagaaggatgggc
ctggagacgcacaagttggcctcgctctggaaggaccgtgctgtcgtcgagatcaatgtc
gcggtgctccacagtttccagaagcaaaacgtgaccatcatggaccaccactcagccgca
gagtccttcatgaagtacatgcagagcgagtaccggtcccgggggggctgccctgccgac
tggatttggctggtgcccccgatttctggaagcatcactcctgtgttccaccaagagatg
ttaaactatgtcctgtcccctttcttctactaccaggtggaggcctggaaaacccatgtc
tggcaggatgagacgcggagaccccggagaaggaaggttccgttccgagtcttggttaaa
gctgtgctcttcgcctccatgctgatgcgcaagaccatggcgtcccgagtccaagccacc
atcctctttgcgacggagacgggaaagtcagaaacgctggcccgggacctaggagccttg
ttcagctgtgccttcaaccccaaggtcctctgcatggaccagtaccggctgagcaacctg
gaggaagagcagctgctgctggtggtgaccagcacgtttgggaacggagactcccccagc
aacggagagaaactgaaaaagtccctcttcatgctgaaagagcttaccaacaagttcagg
tatgccgtgtttggcctcggctccagcatgtaccctcggttctgcgcctttgctcacgac
atcgaccagaagctgtcccatctgggggccactcagctcgcccccacaggggaaggggat
gagctcagtggacaggaggaagccttccgcggctgggccgtgcaaaccttcaaggcagcc
tgtgagacgttcgacgtgcgaggcaagcacctcattcagatccccaagctctacacgtcc
aacgtgacctgggacccacaccgctacaggctcgtgcaggactcacagcctctggacctc
aacaaagccctcagcagtatgcacgccaagaacgtgttcaccatgaggctcaaatcacag
cagaacctccagagtccgcagtccagccgcgccaccctcctggtggtgctctcctgtgag
gatggccaccggctgagctacgtgcccggggagcacctcggggttttcccaggcaaccag
ctggctctggtgcgaggcatcttggagcgggtggtggacggccctgcaccccaccagccc
gtgtgcctggagaccctcagcgagagcggaagctactgggtcagagacaagcggctgccc
ccatgctcgctcagccaggccctcacctacttcctggacatcaccaccccccctacgcag
ctgctgctccgcaaactggcacagctggccacggaggaggcagagaggcagcggctggag
accctgtgccagccctcagagtacaacaagtggaagttcaccaatagccccacattcctg
gaggtgctggaggagttcccgtccctgcgcgtgtctgctggcttcctgctctcccagctg
cctattctgaaaccccggtactactccatcagttcgtgcagggcccgtacacccacggag
gtccacctcactgtggctgtgctcacgtaccgcacccgagatggccaaggtcccttgcac
cacggtgtctgcagcacatggctcagcgggctgaagccccaagacccagtaccctgcttt
gtgagaagtgtcggcggcttccagctgcccgaggacccctcccagccctgcatcctcatt
gggcctggcacaggcatcgcccccttccgcagcttctggcagcagcggctccatgacgcc
gagcacaaagggctccggggcggccgcatgaccctggtgtttgggtgccgccgccccgag
gaggaccacctctatcgggaggagatgttggagatggcccagaagggggtgctgcatgcg
gtgcacacagcctattcgcgcctgcctggccagcccaaggtctatgttcaagatgtcctg
cggcagcggctggccagcgaggtgctccgcgtgctccatgaggagcagggccacctgtat
gtctgcggggacgtgcgtatggcccgggatgtggcccttaccctgaagcacctgctggcc
gccaagctgagcctgagcgaggagcaggttgaggactatttcttccaacttaagagccag
aagcgctaccatgaagatatcttcggtgctgtctttccctacgaagtgaagacggacggg
gccacaaggcagcccagcaatccccaagtgccagcagcccatgggccacgtgacagttgc
tgccacggaacttaa
DBGET
integrated database retrieval system
