Hyaena hyaena (striped hyena): 120248043 Help Entry 120248043         CDS       T07257                                  Symbol ITGA2 Name (RefSeq) integrin alpha-2 isoform X1   KO K06481   integrin alpha 2 Organism hhv  Hyaena hyaena (striped hyena) Pathway hhv03271   Virion - Rotavirus hhv04145   Phagosome hhv04151   PI3K-Akt signaling pathway hhv04510   Focal adhesion hhv04512   ECM-receptor interaction hhv04611   Platelet activation hhv04640   Hematopoietic cell lineage hhv04810   Regulation of actin cytoskeleton hhv04820   Cytoskeleton in muscle cells hhv05165   Human papillomavirus infection hhv05200   Pathways in cancer hhv05205   Proteoglycans in cancer hhv05222   Small cell lung cancer hhv05410   Hypertrophic cardiomyopathy hhv05412   Arrhythmogenic right ventricular cardiomyopathy hhv05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:hhv00001]  09120 Genetic Information Processing   09125 Information processing in viruses    03271 Virion - Rotavirus     120248043 (ITGA2)  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     120248043 (ITGA2)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     120248043 (ITGA2)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     120248043 (ITGA2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     120248043 (ITGA2)   09142 Cell motility    04820 Cytoskeleton in muscle cells     120248043 (ITGA2)    04810 Regulation of actin cytoskeleton     120248043 (ITGA2)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     120248043 (ITGA2)    04611 Platelet activation     120248043 (ITGA2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     120248043 (ITGA2)    05205 Proteoglycans in cancer     120248043 (ITGA2)   09162 Cancer: specific types    05222 Small cell lung cancer     120248043 (ITGA2)   09172 Infectious disease: viral    05165 Human papillomavirus infection     120248043 (ITGA2)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     120248043 (ITGA2)    05412 Arrhythmogenic right ventricular cardiomyopathy     120248043 (ITGA2)    05414 Dilated cardiomyopathy     120248043 (ITGA2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hhv04147]     120248043 (ITGA2)    04515 Cell adhesion molecules [BR:hhv04515]     120248043 (ITGA2)    04090 CD molecules [BR:hhv04090]     120248043 (ITGA2) Exosome [BR:hhv04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    120248043 (ITGA2)   Exosomal proteins of bladder cancer cells    120248043 (ITGA2) Cell adhesion molecules [BR:hhv04515]  Integrins   Integrin alpha subunits    120248043 (ITGA2) CD molecules [BR:hhv04090]  Proteins   120248043 (ITGA2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  VWA FG-GAP Integrin_A_Ig_2 Integrin_A_Ig_3 VWA_2 FG-GAP_3 FG-GAP_2 vWA_SIBA-E HisK_sensor ITGAX-like_Ig_3 Integrin_alpha Motif Other DBs NCBI-GeneID:  120248043 NCBI-ProteinID:  XP_039112139 LinkDB All DBs Position Unknown AA seq 1178 aa AA seqDB search MRPGWTGGAPLLVLLLSQGILKCCMAYNIGLLGAKIFSGPSSEQFGYAVQQFINPKGNWL LVGSPWSGFPENRMGDVYKCPIDLSTATCEKLNLETATTIPNVTEMKTNMSLGLTLTRNL GTGGFLTCGPLWAQQCGSQYYATGVCSDISPDFQLLASFAPAVQTCPSLIDVVVVCDESN SIYPWEAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVIFNLNTFKTKDAMIEATSRTY QFGGDLTNTFKAIQYAKDFAYKAAAGGRPGATKVMVVVTDGESHDGSMLKAVIDECNNDN ILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFS IEGTIQGGDNFQMEMSQVGFSADYSPQKDILMLGAVGAYAWSGTVVQQTSHGHLIFPKQA FDQILQDKNHSSYLGYSVATISTGKGIHFVAGAPRANYTGQIVLYRVNENGNVTIIQAHR GDQIGSYFGSVLCSVDVNKDSVTDVLLVGAPMYMNDLKKEEGRVYLFTITKGILNWHQFL EGPDGVENSRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHEGTIHMNYSQK ILGSDGAFRSHLQYFGRSLDGYSDLNGDSITDVSIGAFGQVVQLWSQSIADVSVNASFTP EKITLFNKNADIKLKLCFSAKFRPTKQNSQVAITYNITIDADLYSSRVTSRGLFKENNER CLQKNMTVSQTQSCSEYIIHIQKPSDVVSSLDLCVNISLENPGTSPALEAYSEKAKVFSI PFYKDCGDDGVCSSDLVLDVQQLSAAQDQPFIVSNQNKRLTFSVMLKNKRESAYNTGIVI DFSENLFFASWTMPVDGTEVICQIASSQKSVTCDVGYPALKRQQQVTFMINFDFNLQNLQ NQASLNFQALSESSEENKADNLVNFKIPLLYDADIHITRSTNINFYEVSSDGNIPSIVHS FEDIGPKFIFSVKVTTGSIPVSMASMIIHIPQYTKEQNPLMYVTGVHTDQAGDISCNAEI NPLKIGHTASSVSFNSENFRHIKELNCRSASCSNVTCWLKDLQVKREYFLNVSTRIWNGT FAASTFQTVQLTASAEIDTYNPQIYVIEENTVTIPITIMKPHEKAEVPTGVIVGSVIAGI LLLLALVAVLWKLGFFKRKYEKMSKTADEIDETTELNS NT seq 3537 nt NT seq  +upstreamnt  +downstreamnt atgcggccaggatggacggggggtgcgcccttgctggtgttactgctcagtcaaggcatt ttaaaatgttgtatggcatacaatatcggtctcctaggagcaaagatattttccggtcct tcaagtgaacagtttggctatgctgtgcagcagtttataaatccaaaaggcaactggtta ctagttggttcaccttggagtggctttcctgagaacagaatgggagatgtgtataaatgt cctatagatctgtccactgctacatgtgaaaaactgaatctggaaactgctacaaccatt cccaacgttaccgaaatgaaaaccaacatgagccttggcttgacactcacaaggaactta ggaaccggaggatttctcacgtgcggtcccctgtgggcacaacagtgcggaagccagtat tatgcaactggtgtttgttctgatatcagtcccgattttcagctcttggccagctttgca cctgcagttcagacctgcccttctctcatagatgttgtggttgtatgtgatgagtcaaac agtatttatccctgggaagcagtaaagaattttttggaaaaatttgtccaaggcctggat ataggccccacaaagacacaggtggggttaattcagtatgccaacaatccaagagttata tttaacctgaacactttcaaaaccaaagatgcaatgattgaagcaacatcccggacatac caatttggtggagatctcacaaatacattcaaagcaattcaatatgcaaaagatttcgct tataaggcagctgccggaggacgaccaggtgctaccaaagtaatggtggttgtaactgat ggtgaatcgcatgatggttccatgttgaaggccgtgattgatgaatgcaacaatgacaat atattgaggtttggcatagcggttcttgggtacttaaacagaaatgcccttgacactaaa aatttaataaaagaaattaaagcaattgccagtattccaacagaaagatattttttcaat gtgtctgatgaagcagctctactagaaaaggctggtacactcggagaacaaatttttagc attgaaggtactattcaaggaggggacaacttccagatggaaatgtcacaagtgggattc agcgcagattactctcctcaaaaggatattctgatgctgggtgcagtaggagcttatgcc tggagtggtactgtggtccagcagacatctcatggacatttgatctttcctaaacaagcc tttgaccaaattctgcaagataaaaatcacagttcatacttaggttactctgtggctacg atttctactggaaaaggcattcactttgttgctggtgctcctcgggcaaattatactggc cagatagtgctatacagggttaatgagaatggcaatgtcaccattattcaagctcaccga ggtgaccagattggctcctattttggtagtgtgctgtgctcagttgacgtgaataaagac agtgttacagatgtgctcctggtgggtgcacctatgtacatgaatgacctaaagaaagag gaaggaagagtctacctatttactatcacaaagggcattttgaattggcaccaatttctt gaaggccctgatggtgttgaaaattctcggtttggttcagcgattgcagctctttcagat atcaacatggatggttttaatgatgtaatagttggttcacccttggaaaatcagaactct ggagctgtgtacatctacaatggtcatgagggcaccattcacatgaattattcccagaaa atcttgggatctgatggagcctttaggagccatctccaatactttgggagatctttggat ggctacagtgatttaaatggggattccatcaccgatgtgtccattggagcttttggacaa gtggttcagctctggtcacagagtattgctgatgtatctgtgaatgcttccttcacacca gaaaaaattactttgttcaacaagaatgctgacataaaactcaaactctgtttcagtgca aagtttagacctactaagcaaaacagtcaagtggccattacatacaatatcacaattgat gcagacctgtattcatccagagtaacctctagagggttatttaaagaaaataatgaaaga tgcctgcagaagaatatgacagtaagtcaaacacagagttgctctgagtacatcatccac atacagaaaccctccgatgttgtcagctctttggatctgtgtgtgaacatcagtctggaa aaccctggcaccagccctgcgcttgaagcctactctgagaaggccaaggtcttcagtatc cctttctacaaggactgtggggatgacggagtctgcagctctgatctagttctagatgtc caacagctgtcagctgctcaagatcaaccctttattgtcagcaaccaaaacaaaaggtta acattttcagtaatgctgaagaataaaagggaaagtgcctacaacactggaattgttatt gatttttcagaaaacttgttttttgcttcctggaccatgccggttgatggaacagaagtc atatgccagattgcttcatctcagaagtctgttacctgtgatgtaggctaccctgcttta aagagacagcaacaggtgactttcatgattaactttgacttcaatcttcaaaaccttcag aatcaggcatctctcaatttccaagccttaagcgaaagctctgaagaaaacaaggcagat aatttggtcaatttcaaaatccctctgctgtatgacgctgatattcatataacaagatct accaatataaatttctatgaagtctcctcagatgggaatattccttcaatcgtgcacagt tttgaagatattggtccaaaattcatcttctctgttaaggtaacaacaggaagcatccca gtcagcatggcatccatgatcatccacatccctcaatacaccaaagaacagaacccgttg atgtacgtgactggggtgcacacagatcaggctggcgacatcagttgtaatgccgaaata aatccactgaaaataggacacacggcttcttctgtatctttcaacagtgaaaatttccgg cacataaaagaattgaactgcagaagtgcttcatgtagtaatgttacctgctggctgaaa gacctccaggtcaaaagagagtacttccttaatgtgtcaaccagaatttggaacgggact tttgcagcatcaaccttccagacagtacagctgacggcatctgcagaaatcgacacctat aacccccagatatatgtgatcgaagaaaacacagtcacgattcccattacgataatgaaa cctcatgagaaagctgaagtaccaactggagttatagtaggaagtgtaattgctggaatc cttttgctattagctctggttgcggttttatggaagctcggcttcttcaaaagaaaatat gaaaaaatgtccaaaactgcggatgagatcgacgagaccacagaactcaacagctga

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