Hathewaya histolytica: NCTC503_00580
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Entry
NCTC503_00580 CDS
T05971
Symbol
cysG_2
Name
(GenBank) uroporphyrinogen III synthase/methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
hhw
Hathewaya histolytica
Pathway
hhw00860
Porphyrin metabolism
hhw01100
Metabolic pathways
hhw01110
Biosynthesis of secondary metabolites
hhw01120
Microbial metabolism in diverse environments
hhw01240
Biosynthesis of cofactors
Module
hhw_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
hhw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
NCTC503_00580 (cysG_2)
Enzymes [BR:
hhw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
NCTC503_00580 (cysG_2)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
NCTC503_00580 (cysG_2)
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Motif
Pfam:
HEM4
TP_methylase
FANCI_S1-cap
Motif
Other DBs
NCBI-ProteinID:
VTQ84607
UniProt:
A0A4V6KC18
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All DBs
Position
1:608943..610439
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AA seq
498 aa
AA seq
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MKGKVFLVGAGPGDYKLLTLKGLDCVKNADVIVYDRLANEKILKWAKEDCEFIYVGKKSK
YHTKTQDEINEIIAEEALKGKVVTRLKGGDPYVFGRGGEEGEFLLEKGVKFEVVPGITSA
IGGLCYAGIPITHRDFASSFHVITGHLKEEENELNWSALAQLDGTLVFLMGVANLQKICN
NLIKEGKDSKTSVAIVNWAARPYQRVVSGTLEDIYEIAMEANIQPPSLIVVGGVVGLRDK
LNFYEEKPLFGKNVIVTRARTQSSKLLDKINDLGGNALEVPAIKIKEIENSGLDKAIENI
KDYTTLVLTSENAVNIFFERLFKGNKDIRSLSNFKIACIGNATAKAVKEKGIIADLVPEK
FVAESLLELLKENLTSEDKVLIPRAKEARNLLVDELKEICSVDEIKIYETLKEDIHREDI
LNVLEKENDLYVTFTSSSTVKNFIDILGKENLNLIKDKAKLVSIGPITSKTIENFGLTVH
KEAKEYTIDGVVEAIIEE
NT seq
1497 nt
NT seq
+upstream
nt +downstream
nt
atgaaaggtaaagtttttttagttggagctggaccgggagattataagttacttacacta
aaaggtttagactgtgtaaaaaatgcagatgttattgtatacgatagacttgctaatgaa
aaaattttaaaatgggcaaaagaagattgtgagtttatttatgttggtaaaaaatctaag
tatcatactaaaactcaagatgaaataaatgaaataatagcagaagaagctttaaaaggt
aaagttgtaacaagacttaaagggggagacccttatgtatttggtagaggtggagaagaa
ggcgaatttttacttgaaaaaggtgtaaagtttgaagtagtacctggtataacttcagct
ataggtggactatgctatgctggtattccaataactcatagagattttgcatcatcattc
cacgttataactggacatttaaaagaagaagaaaatgaacttaactggagtgcattagcc
cagttagatggtactttagtattcttaatgggtgttgcaaaccttcaaaagatatgtaat
aaccttataaaggaagggaaagactctaaaacatctgtggctattgtaaattgggcagca
aggccttatcaaagagtggtttcaggaacattagaagatatatatgaaatagctatggaa
gctaatattcagccaccaagtctaattgttgtaggtggagttgttggacttagagataag
ctaaacttctatgaagaaaaaccccttttcggtaaaaatgttatagtaaccagagcaaga
actcaaagtagtaagcttttagataaaataaatgatttaggcggaaacgctttagaagta
cctgcaatcaaaataaaagaaatagaaaatagtggtcttgacaaggctatagaaaatatt
aaagattacacaactctagttcttactagtgaaaatgcagtaaatatattctttgaaaga
ttatttaaaggaaataaagatataagaagtctttcaaattttaaaatagcatgtatagga
aatgctactgcaaaggctgttaaagaaaaaggaataattgcagatttagtaccagaaaaa
tttgtagcagaaagtcttttagaattattaaaagaaaatcttacaagtgaggataaagta
ttaataccaagagctaaggaagctagaaatcttttagttgatgaattaaaagaaatatgt
tctgtggatgaaattaaaatttatgaaactttaaaagaggatattcatagggaagatatt
ttaaatgtactggaaaaagagaatgatttatatgtaacatttactagttcttctacagtt
aaaaactttatagatatattaggaaaagagaacttaaatttaataaaagataaagccaaa
ttagtatcaataggaccaataacttcaaaaactatagaaaattttggcctaacagtacat
aaagaggcaaaagagtatacaatagatggtgtagtagaggctataatagaagagtag
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