KEGG   Hathewaya histolytica: NCTC503_01899
Entry
NCTC503_01899     CDS       T05971                                 
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
hhw  Hathewaya histolytica
Pathway
hhw00230  Purine metabolism
hhw00670  One carbon pool by folate
hhw01100  Metabolic pathways
hhw01110  Biosynthesis of secondary metabolites
Module
hhw_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:hhw00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    NCTC503_01899 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    NCTC503_01899 (purH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hhw04147]
    NCTC503_01899 (purH)
Enzymes [BR:hhw01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     NCTC503_01899 (purH)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     NCTC503_01899 (purH)
Exosome [BR:hhw04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   NCTC503_01899 (purH)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS
Other DBs
NCBI-ProteinID: VTQ92069
UniProt: A0A4U9RJM3
LinkDB
Position
1:complement(1874379..1875884)
AA seq 501 aa
MKRALISVFYKEGILEFAKFLEERGVEIISTGGTYKHLKENGVNVIDVSEVTGFDEILDG
RVKTLHPKVHGGILAIRENEKHMKVLKEKEITPIDMVVVNLYPFFEKVKEDLNFEDKIEF
IDIGGPTMLRSAAKNFKDVVVISDTKDYKKVMEEIADGNNVSLKTRRYLAGKVFNLTSAY
DAAISNFILEEEYPNYLSLSYEKAMDLRYGENPHQSAALYKDTNGEGLINNYTQLNGKEL
SYNNIKDMDIAFKVVCEFEEAACCALKHNTPCGVAVESHGDGIKDVYSKAFQCDPISIFG
GVVALNRTVDKSTAEEMVKIFLEIVIAPDFTEEALEVLRSKKNLRVIKCELKRENKKELV
KVDGGILVQSTDNKLIDEIKVVTEKKPTEKDMKDLIFGMKVVKYVKSNAIVVVKDGMAKG
IGGGQVNRIWATVEALDRAKDGVVLASDAFFPFRDCVDEAHKYNIKAIIQPGGSRGDEES
IKACDEHGIAMVFTGIRHFKH
NT seq 1506 nt   +upstreamnt  +downstreamnt
atgaagagagctttaattagtgttttttataaggaagggattctagaatttgcaaagttt
ttagaggaaagaggagtagagattatatctactgggggaacttataaacatttaaaggaa
aatggagtaaacgttatagatgtttcagaagtaacgggctttgatgaaatattagacgga
cgtgtcaagacccttcatccaaaggttcatggaggaatattagccataagggaaaatgaa
aaacatatgaaagttttaaaggaaaaagaaataacaccaatagatatggttgttgtaaat
ctttatcctttctttgaaaaagtaaaagaagatttaaactttgaagataagatagagttt
atagatattggtggccctactatgctaagatctgcggctaaaaattttaaggatgtagtt
gtaatttcagatactaaggactataaaaaagttatggaagagatagctgatggaaataat
gtatcacttaaaacaagaagatatttagcaggaaaagtatttaatctaacatcagcttac
gatgctgctattagtaattttattttagaagaagagtatccaaactacttatctttatct
tatgaaaaagctatggacttaaggtatggtgaaaatcctcatcaaagtgctgctctttat
aaagatactaacggagaaggattaataaataattatactcagctaaatggtaaagaacta
tcttataacaatataaaagatatggatatagcatttaaagtagtatgtgagtttgaagag
gctgcctgttgtgcattaaaacataatacgccttgtggagtagcagttgagagccatggt
gatggtataaaagatgtgtactcaaaagcatttcaatgtgatcctatatcaatttttgga
ggagtagtagccttaaataggactgtagataagagtacagcagaggaaatggttaaaata
tttttagaaattgttatagctccagattttacggaagaagctttggaggttttaagatct
aagaaaaatctaagagtaattaaatgtgaacttaaaagagaaaataaaaaagaactagta
aaagtagatggtggtatactagtacaaagcacggataataaattaatagatgaaataaaa
gtagttacagaaaaaaaacctacagaaaaagatatgaaagatttaatatttggcatgaag
gttgtaaaatatgtaaaatctaatgctatagttgtagttaaagatggaatggctaaaggt
attggtggtggtcaagtaaataggatttgggctacagtggaagctctagatagagctaaa
gatggagtagtccttgcatcagatgctttcttcccatttagagattgtgtagacgaagca
cataaatacaacataaaggctataattcaaccaggtggttcccgtggtgatgaggaatct
ataaaagcatgtgatgaacatggaattgctatggtatttacgggtataagacattttaaa
cattaa

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