Hathewaya histolytica: NCTC503_01906
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Entry
NCTC503_01906 CDS
T05971
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
hhw
Hathewaya histolytica
Pathway
hhw00230
Purine metabolism
hhw01100
Metabolic pathways
hhw01110
Biosynthesis of secondary metabolites
Module
hhw_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
hhw00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NCTC503_01906 (purL)
Enzymes [BR:
hhw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NCTC503_01906 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
DJ-1_PfpI
NapD
FGAR-AT_PurM_N-like
GATase_3
Motif
Other DBs
NCBI-ProteinID:
VTQ92111
UniProt:
A0A4U9RL89
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All DBs
Position
1:complement(1880592..1884383)
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AA seq
1263 aa
AA seq
DB search
MHPNIHRAFVEKKLNFNVEAQNLLKDLKENLCIKGLENLRLVNRYDIFGIENEEFEKVIK
YILSEPNVDDVFEENINDKGDRLFAVEYLEGQYDQRKDAAEQCIRLILEGKECIVKNAKV
IILYGSISDEEFQKIKNYYINKVDSKEASIEKPESLKVNLNIKNEVQSLLGFTELNEEGL
RDFIEKQSLAMNFEDIKLVQDHFRKEKRIPTITEIKVIDTYWSDHCRHTTFNTIIENVEF
EGGKYTEPVKETYEEYLKIRKQVYKNKYKEKSLMDMAVIGMKNLRKLGKLDDLDESDEIN
ACSIVIPVDINGNEEKWLLMFKNETHNHPTEIEPFGGASTCLGGAIRDPLSGRSYVYQAM
RVTGSADPRMPIEDTLKGKLPQSKITKEAARGYSSYGNQIGLATGQVTELYHEDFMAKRM
EVGAVIGAAPYTNVRRENPSPGDVVILLGGRTGRDGCGGASGSSKEHDEKSILNCGAEVQ
KGNAPTERKIQRLFRNPKVVSMIKKCNDFGAGGVSVAIGELADGLIIDLDKVPKKYEGLD
GTELAISESQERMAVVIEKENIDKFINYAEKENLEATVVAEVTEEKKVIMKWKDKIILNL
DRDFLDTNGAKQYINIKVASPSEDDYFKQRSENYKDKNLAERFLKNLQDLNICSQKGLTE
MFDSTVGAGTVFMPFGGKYQLTPNEVMACKIPVLEGETNTASLMSYGYNPKIGKWSPFHG
AMYSVVESITKIVAAGGDYSKIRLSFQEYFEKLYDNPEKWGKPFTALLGALHVQNKLGIP
AIGGKDSMSGTFKDINVPPTLVSFAVTHAKTYNLITPEFKKANNHVVLFKAVRGADGVTH
FDILKNNFNVVHKLISERKIISASSVKYGGIAESIAKMTFGNKIGFKFKTEFNKENIFSS
DYGSILAEFNGDISILDKYKGISYEIIGKTLKKEEIVLDCENKISIDKAIDVWSNPLEGI
FKTEYHSEQSEIFKFSIEEPKFIGKAYNKKSNLLIKDVKPKVLIPVFPGTNCEYDCMKAF
EKAGGDAEIFIFNNMNNYKIKESIDEMASRIKESQIIMIPGGFSAGDEPDGSGKFISAVF
RNEKIKDSVRELLNVRDGLILGICNGFQALIKLGLLPYGDIVDIKEDSPTLTFNAIGRHI
SCITNTKIVSTKSPWFNLVHEGDIHNVPVSHGEGRFYATEDVTKELFSKGQVATQYVDLS
GKPTYDVRYNPNGSLMAIEGITSPDGRILGKMGHSERIGNELYKNVPGEYDQKIFKSGIE
YFK
NT seq
3792 nt
NT seq
+upstream
nt +downstream
nt
atgcatccaaatattcatagggcttttgtagaaaagaaactaaattttaatgttgaggcg
caaaaccttttaaaagatctaaaagaaaatctttgtataaaaggtttagaaaatctaaga
ttagtaaataggtatgatatttttggaatagaaaatgaggagtttgagaaggtaataaag
tatattttaagtgagcctaatgtagatgatgtttttgaagagaatataaatgacaaaggg
gatagactgtttgcggtagaatatttggaaggacaatatgaccaaagaaaagatgctgcg
gaacaatgcattagacttatactcgagggtaaagagtgtatagttaagaatgcaaaagtc
ataatattatacggaagcatctctgatgaagaatttcaaaaaataaagaattactatatt
aataaagttgattctaaagaggcaagtatagaaaaacctgaaagtttaaaggttaattta
aatattaaaaatgaagttcaaagtttattaggatttacagaacttaatgaggaaggactt
agggattttatagaaaaacaaagtcttgctatgaattttgaagatataaaattagtacaa
gatcattttagaaaagaaaaaagaatacctactataacggaaataaaggttatagatacg
tattggtcagatcactgtaggcatactacatttaatactataatagaaaatgttgagttt
gaaggtggaaagtatacggaaccggtaaaagaaacttatgaagaatatttaaagataaga
aagcaagtttataaaaataaatataaagagaaatctttaatggacatggctgtaattggg
atgaaaaacctcagaaagttaggcaaactagatgatttagatgaatctgatgagataaat
gcatgcagtatagttattccagtggatattaatggaaatgaagaaaaatggcttttaatg
tttaagaatgaaacccataaccacccaacagaaatagaaccttttggaggtgcatccact
tgtcttggtggcgctatacgtgatcctttatcagggagaagctatgtatatcaagctatg
cgtgtaacaggatctgcagatccaagaatgcctatagaagatacattaaaaggaaaactt
cctcaaagtaaaataacaaaagaggctgcaagaggatacagtagctatggaaatcaaata
ggccttgctacaggacaagttacagaattatatcatgaggattttatggcaaaaagaatg
gaggttggagctgttataggtgcagcaccatatacgaatgttagaagagaaaatccaagt
cctggggatgtagttatattgttaggaggtagaactgggagagatggatgtggtggagca
tcaggttcatctaaagaacatgatgaaaaatctatattaaattgtggcgctgaagttcaa
aaaggaaatgcacctacagaaagaaaaattcaaagattatttagaaatcctaaagttgta
agtatgattaaaaaatgtaatgactttggagcaggtggagtttcagttgctataggagaa
ctagcagatggactaattatagatttagataaggttcctaaaaagtatgaaggcttagat
ggaacagaacttgctatatctgaatctcaagagcgaatggctgtagttatagagaaagaa
aacatagacaaatttataaattatgctgaaaaagaaaatttagaagcaacagtagtagca
gaggttactgaagagaaaaaagtaattatgaagtggaaagataaaataatattaaattta
gatagagattttttagatactaatggggcaaaacagtatatcaatataaaagttgcctct
ccatctgaggatgattactttaaacaaagaagtgaaaattacaaggataaaaatttagca
gaaagatttttaaagaatcttcaagatctgaatatatgttcacaaaaaggtttaactgaa
atgtttgatagtactgtaggagcaggaacagtatttatgccttttggaggtaagtaccaa
cttactcctaatgaggttatggcatgtaaaataccagttttggaaggagaaacaaataca
gcttctctaatgtcttatggatacaatcctaaaatagggaaatggagtcctttccatggg
gcaatgtattctgtagtagaatctattactaaaatagtagcagctggtggggattacagt
aagataagattatcttttcaagaatatttcgagaaactttacgataatccagaaaaatgg
ggtaaaccatttacagctttattaggtgcattacatgttcaaaataaattaggaatacca
gctataggtggtaaggatagtatgtctggaacctttaaggatataaatgttcctccaacc
ctagtttcttttgcagtaactcatgctaagacatataatttaattactccagagtttaaa
aaggctaataatcatgtagttttatttaaggctgtgagaggagcagatggagttacacat
tttgatattttaaagaataattttaatgtagtacacaaattaataagtgaacgaaaaata
atatctgcatcatcagttaagtatggtggaatagctgaaagcatagcaaaaatgactttt
ggaaataaaattggttttaaatttaaaactgaatttaataaagagaatatattctccagt
gattatggtagtattttagctgaatttaacggagatataagtatattagataaatataaa
ggtatttcttatgaaataataggcaagacattgaaaaaagaagaaatagttttagattgt
gagaataagatatccatagataaggccatagatgtgtggagcaatcctttagaaggaatt
tttaaaactgaataccattctgaacaaagtgaaatttttaaatttagcatagaagagcct
aaatttataggaaaggcatataataagaaaagtaatcttcttattaaagatgtaaaacca
aaagttttaattccagtgttcccaggtacaaattgtgagtatgattgtatgaaggctttt
gaaaaagctggtggtgatgctgaaatatttatatttaataatatgaataattataaaata
aaagagtctatagatgaaatggcaagtagaataaaagaaagccagattataatgattccg
ggtggatttagtgcaggagatgaaccagatggttcgggaaaatttatatcagctgtattt
agaaatgaaaagataaaagattccgtaagagaacttttaaatgtaagggatggattaata
ttaggaatatgtaatggattccaggctttaattaaactaggtcttctgccttatggtgat
attgtagatattaaggaggattcaccaaccttaacatttaatgctataggaagacatata
tcttgcataacaaatacaaagattgtgtctacaaagtcaccatggtttaatttggtacat
gaaggagatatacacaatgtacctgtatcacatggagaaggtagattttatgcaacagaa
gatgtgacgaaggaattgttttcaaaaggacaagtggcaactcaatacgtagatttaagt
ggaaaacctacttatgatgtaagatacaatcctaatggttctttaatggctattgaggga
attactagccctgatggaagaatcttagggaaaatgggtcactcagagagaataggaaat
gaattatacaaaaatgtacctggggagtatgatcaaaaaatatttaaatcaggaattgaa
tattttaaataa
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