Haemophilus haemolyticus: NCTC10839_00005
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Entry
NCTC10839_00005 CDS
T06216
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
hhz
Haemophilus haemolyticus
Pathway
hhz00290
Valine, leucine and isoleucine biosynthesis
hhz00660
C5-Branched dibasic acid metabolism
hhz01100
Metabolic pathways
hhz01110
Biosynthesis of secondary metabolites
hhz01210
2-Oxocarboxylic acid metabolism
hhz01230
Biosynthesis of amino acids
Module
hhz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hhz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NCTC10839_00005 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NCTC10839_00005 (leuC)
Enzymes [BR:
hhz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
NCTC10839_00005 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
NCTC10839_00005 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
SQH96171
UniProt:
A0A2X4R2R6
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Position
1:complement(4214..5623)
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AA seq
469 aa
AA seq
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MAKTLYEKLFDAHVVYEAEGETPILYINRHLIHEVTSPQAFDGLRVAGRQVRQVSKTFGT
MDHSISTQVRDVNKLEGQAKIQVLELAKNTKATGIQLFDMTTKEQGIVHVMGPEQGLTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQARAKNMKIEVRGKVAPGITA
KDIILAIIGKTTMAGGTGHVVEFCGEAIRDLSMEGRMTVCNMAIEMGAKAGLIAPDETTF
EYLKGRPHAPKGKDWDDAVAYWKTLKSDEDAIFDTVVILDAKDIAPQVTWGTNPGQVISV
NETIPNPQEMADPVQRASAEKALHYIGLEAGTNLKEVKVDQVFIGSCTNSRIEDLRAAAA
VMKGRKKADNVKRILVVPGSGLVKEQAEKEGLDKIFIEAGAEWRNPGCSMCLGMNDDRLG
EWERCASTSNRNFEGRQGRNGRTHLVSPAMAAAAGMFGKFVDIRDVTLN
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atggcaaaaactctttacgaaaaattattcgatgcccacgtggtatacgaagctgaaggc
gaaacgccgattttgtatattaaccgtcatttaatccatgaagtgaccagtccacaagcc
tttgatggtttacgtgtggcaggccgtcaagtgcgccaagtaagcaaaactttcggtacc
atggatcacagcatttctactcaagtacgtgatgtgaataaacttgaaggtcaagcgaaa
attcaagtattagaactcgcaaaaaacacaaaagcgactggtattcaattattcgatatg
accaccaaagagcaaggaatcgtgcatgtgatggggcctgaacaaggcttaaccttaccg
ggcatgactatcgtttgtggtgactcccatactgccactcatggtgcattcggtgctttg
gcatttggtattggtacatccgaagtagaacacgtattagccacacaaaccttaaagcaa
gctcgcgcaaaaaatatgaaaattgaagtgcgtggcaaagtagcaccaggcattaccgca
aaagatattattcttgccatcatcggtaaaacaaccatggcgggcggtacaggccatgtg
gtggaattctgcggtgaagcgattcgtgatctttccatggaaggccgtatgaccgtatgt
aatatggcgattgaaatgggcgcgaaagccggcttaatcgcaccggatgaaactactttc
gaatacttaaaaggtcgtccacatgcaccgaaaggtaaagattgggatgatgctgtcgct
tattggaaaaccttaaaatctgatgaggatgcaatatttgatacagtggtgatattggat
gcaaaagacatcgcaccacaagtaacttgggggacaaacccagggcaggtgatttctgtg
aatgaaaccataccaaatccgcaagaaatggcagatcctgtacaacgagcttcggcggaa
aaagccttacactatattggtttggaggctggcactaatttaaaagaagttaaagttgat
caagtatttatcggatcttgtaccaactcacgtattgaagatttacgtgcagcagcggcg
gtgatgaaaggacgtaaaaaagccgataacgtaaaacggattttagtggtgccaggttcc
ggtttagtaaaagaacaagcggaaaaagaaggtttggataaaatctttatcgaagcagga
gctgaatggcgtaaccctggttgctcaatgtgtttagggatgaacgatgaccgtttaggc
gaatgggaacgttgtgcttccacgtcaaaccgtaactttgaaggtcgccaagggcgtaat
ggtcgtactcacttggtgagccccgcgatggcagcggctgcgggaatgtttggtaaattc
gttgatattcgtgatgtaacattaaactaa
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