Haemophilus haemolyticus: NCTC10839_01810
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Entry
NCTC10839_01810 CDS
T06216
Symbol
thrA
Name
(GenBank) Aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
hhz
Haemophilus haemolyticus
Pathway
hhz00260
Glycine, serine and threonine metabolism
hhz00261
Monobactam biosynthesis
hhz00270
Cysteine and methionine metabolism
hhz00300
Lysine biosynthesis
hhz01100
Metabolic pathways
hhz01110
Biosynthesis of secondary metabolites
hhz01120
Microbial metabolism in diverse environments
hhz01230
Biosynthesis of amino acids
Module
hhz_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
hhz_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
hhz00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
NCTC10839_01810 (thrA)
00270 Cysteine and methionine metabolism
NCTC10839_01810 (thrA)
00300 Lysine biosynthesis
NCTC10839_01810 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
NCTC10839_01810 (thrA)
Enzymes [BR:
hhz01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
NCTC10839_01810 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
NCTC10839_01810 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
SQH97873
UniProt:
A0A2X4R7F0
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All DBs
Position
1:complement(1865201..1867648)
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AA seq
815 aa
AA seq
DB search
MRVLKFGGTSLANPERFSQAAKLIEQAHLEEQAAGVLSAPAKITNHLVALSEKAALNQPT
DTHFNEAIEIFYNIINGLHAENNQFDLNGTKALIDAEFAQIKGLLEEIRQAGKVEDAVKA
TIDCRGEKLSIAMMKAWFEARGYSVHIVDPVKQLLAKGGYLESSVEIEESTKRVDAASIA
KDKVVLMAGFTAGNEKGELVLLGRNGSDYSAACLAACLGASVCEIWTDVDGVYTCDPRLV
PDARLLPTLSYREAMELSYFGAKVIHPRTIGPLLPQNIPCVIKNTGNPSAPGSIIDGNVK
SEGLQVKGITNLDNLAMFNVSGPGMQGMVGMASRVFSAMSGAGISVILITQSSSEYSISF
CVPVKSAEVAKTVLETEFSNELNEHQLEPIEVIKDLSIISVVGDGMKQAKGIAARFFSAL
AQANISIVAIAQGSSERSISAVVPQNKAIEAVKATHQALFNNKKVVDMFLVGVGGVGGEL
IEQVKRQKEYLAKKNVEIRVCAIANSNRMLLDENGLCLDDWKNDLENATQPSDFDVLLSF
IKLHHVVNPVFVDCTSAESVAGLYARALKEGFHVVTPNKKANTRELAYYNELRQNAQASQ
HKFLYETNVGAGLPVIENLQNLLAAGDELEYFEGILSGSLSFIFGKLEEGLSLSEVTALA
REKGFTEPDPRDDLSGQDVARKLLILAREAGIELELSDVEVEGVLPKGFSEGKSADEFMA
MLPQLDEEFKTRVSTAKAEGKVLRYVGKICEGKCKVSIVAVDQNNPLYKVKDGENALAFY
TRYYQPIPLLLRGYGAGNAVTAAGIFADILRTLQH
NT seq
2448 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgtacttaaatttggcggcacttcgcttgcaaatccagaacgtttttcccaagca
gcgaaattgatcgagcaagctcatttagaagagcaggcagcaggtgttttatccgcacca
gccaaaataacgaatcatctcgtcgccctttctgaaaaagctgcattaaatcaaccaacc
gatacgcatttcaacgaagcaatcgaaattttctataacatcatcaatggcttacatgcc
gaaaataatcaattcgacttaaatggcaccaaagcgcttattgatgctgaatttgctcaa
atcaaaggattattagaagaaattcgtcaggcaggaaaagtagaagatgcagttaaagcg
acgattgattgccgtggtgaaaaactttctatcgcaatgatgaaggcttggtttgaagcg
cgtggctatagcgtacatattgtggatccagtcaaacaattattggcaaaaggcggttat
cttgaatcttctgttgaaattgaagaatcaacaaaacgtgttgatgcagcaagtatcgca
aaagataaagtggtgcttatggcaggctttactgcgggtaacgaaaaaggtgagttggtg
ctgctcggtcgtaatggctcagattattctgcagcctgtttagccgcttgtttaggcgca
agcgtatgcgaaatttggaccgatgtggatggcgtttatacttgtgatcctcgtttagtg
cctgatgcacgtttattgccaactctttcttatcgtgaagcgatggagctttcttatttc
ggtgcgaaagtgattcatcctcgtacgattggcccattgttgccacaaaatattccttgt
gtcattaaaaatacaggaaatccttctgcgccgggttcgattattgatggcaatgtgaaa
tcagaaggtttacaagtcaaaggtatcactaacttagataacttggcgatgtttaatgta
tcaggccctggtatgcaaggcatggtaggcatggcatctcgcgtattttcagctatgtca
ggtgcaggcatttcagtcatcttaattacccagtcttcatctgaatatagtattagtttc
tgtgtgcctgtgaaatctgcagaagtagcgaaaaccgtactagaaactgaattttctaat
gaattaaatgaacatcaattagaaccaattgaagtgattaaagatttatccattatttct
gttgtgggcgatggaatgaagcaagcgaaaggcattgctgctcgtttcttctctgcgtta
gcacaggcaaatattagcattgtggcgattgcacaaggttctagtgaacgttcaatttct
gcggttgtgccgcaaaataaagcgattgaagcggtgaaggctacccatcaggcacttttc
aataataaaaaagtagtggatatgtttttagtgggcgttggtggagtaggcggagaatta
attgagcaggtaaagcgccaaaaggagtatctagcaaagaagaatgttgaaattcgagtt
tgtgctattgcgaattcaaaccgcatgttgctcgatgaaaatggattgtgtttagacgat
tggaaaaacgatttagaaaatgcgactcagccatcagattttgatgtattgctttctttc
attaaattacatcatgtggtgaatccagtatttgtagattgtacctcagccgaatctgta
gcagggctttatgctcgtgcgttaaaagaaggtttccatgtggttacgccaaataaaaaa
gcgaatacacgagaattagcttattacaatgagttacgccaaaacgctcaagcaagccaa
cataaatttttgtatgaaacgaatgtgggcgctggtttgccagtgattgaaaatcttcaa
aacttacttgccgcgggcgatgaacttgaatattttgaaggtattttatctggctccctt
tcctttatttttggtaaattggaggaaggactttctctttcagaagtcaccgcacttgcg
cgtgaaaaaggctttactgagccagatccccgtgatgacctttcaggacaagatgtagca
cgtaaattattaattcttgctcgtgaagctggaattgaacttgaactttcagatgttgaa
gttgagggggtattgccgaaaggcttctctgaaggaaaatcagcagatgaatttatggca
atgttgccacagcttgatgaagagtttaaaactcgtgtttccaccgctaaagctgaaggc
aaagtattacgttatgttggaaaaatttgcgaaggtaaatgtaaagtatctattgtagca
gtcgatcagaataacccactttataaagtgaaagacggtgaaaatgctttggcattttat
actcgttattaccaaccgatcccacttttattacgtggttatggcgcaggcaatgcggtt
actgcggcaggtatctttgcagatattttaagaacattacaacattaa
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