Haemophilus influenzae C486: NTHIC486_00230
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Entry
NTHIC486_00230 CDS
T03721
Symbol
purL
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
hic
Haemophilus influenzae C486
Pathway
hic00230
Purine metabolism
hic01100
Metabolic pathways
hic01110
Biosynthesis of secondary metabolites
Module
hic_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
hic00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NTHIC486_00230 (purL)
Enzymes [BR:
hic01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NTHIC486_00230 (purL)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
DUF7483
Motif
Other DBs
NCBI-ProteinID:
AJO88999
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Position
complement(214274..218167)
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AA seq
1297 aa
AA seq
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MTVKTFRGSPALSEFRLTQLQQKCQQYQLPITSVYAEYLHFVEQKTSLVEDEIVKLQALL
HYGSMFSELKPAGYCLIVTPRVGTISSWSSKATDIAHNCGLSKVNRIERGIAYYFNIERD
LTEAELATLKDLLHDRMLETVLNHETEAALLFTQQEPKALTTIDILNGGRQALEQANIAL
GLALADDEMDYLVESFTALKRNPQDVELYMFAQANSEHCRHKIFNADWIIDGKKQDKSLF
KMIKNTFEKTPDFVLSAYKDNAAVMEGSKVGRWFPDPDGQYRVHQEDAHILMKVETHNHP
TAISPFPGAATGSGGEIRDEGATGRGAKPKAGLTGFSVSNLVIPNFEQPWENPLSKPNRI
ASALDIMIDAPLGSAAFNNEFGRPALLGYFRTYEEKVNSFAGKEVRGYHKPIMLAGGIGN
IRGEQVQKGEIPVGAKLIVLGGAAMNIGLGGGAASSMDSGKSKEDLDFASVQRENPEMER
RCQEVIDRCWQLGEENPILFIHDVGAGGLSNAMPELVHDGKRGGKFDLRSILCDEKGMSP
LEIWCNESQERYVLAVAPENLELFTALCERERAPFAVIGEATQAEHLILHDSHFDNNPID
LPMNVLLGKTPKMTREVLSKTVENQSLKTEGIQLKEAFHRVLRLPVVAEKTFLITIGDRS
VTGMVARDQMVGPWQIPVSDVAVTTASLDSYHGEAMAMGERSPVALLNFSASARLAVAEA
ITNIAGTHIGEMKRIKLSANWMSAAGHTGEDAGLYEAVKAVGEELCPALGLTIPVGKDSM
SMKTTWIDNGEQKSVTAPLSLVISAFARVEDVRKTLTPQLRTDKGLSSLLLIDLGEGHNR
LGATALAQVYKQLGDKPADVVKVQRLKDFYNAMQTLVAEDKLLAYHDRSDGGLITTLAEM
AFAGHCGVEVDISALGDNDLAVLFNEELGAVIQVTDSQLESVREVLKAHNLLGITHQLGT
VTADDRFEISRGSHKLFSEKRSELRSIWAELTYQMQRLRDNPECAEQEFEAKKNPDDKGL
SAFLTYDVNEDITAPFINKGVKPTIAILREQGVNSHYEMAAAFDRAGFNAIDVHMSDLMI
GRRNLAEFNAMVACGGFSYGDVLGAGGGWAKSILFNPKLHEQFSQFFINPNTLTLGVCNG
CQMISNLAEIIPGTENWPHFVRNKSERFEARVSLVKINEVDSVWFAGMAGSHMPIAVSHG
EGQVKFKSVEQFAGLKAQGIIAAQYIDNNGSPTELYPANPNGSAEGITAITNLDGRVAIM
MPHPERVFRAVSNSWHPENWTEDGAWMRLFRNARMVF
NT seq
3894 nt
NT seq
+upstream
nt +downstream
nt
atgactgtcaaaacctttcgtggctcgcctgctctttctgaatttcgtttaactcaactt
caacaaaaatgccagcaatatcaattgcctattacgtcagtttatgcagagtatttgcat
tttgttgaacaaaaaacatcgcttgtagaagatgaaatcgttaaattacaagcattattg
cattatggatcaatgttttctgaactcaagcctgcaggatattgtttaattgtgactcca
cgagtggggacaatttcctcttggtcttcaaaagcgacggacatcgctcacaattgtggt
ttgtcgaaggtaaatcgtattgaacgtggtatagcctattacttcaatattgagcgtgat
ttaaccgaagcagaattggctacgctgaaagatttattacacgaccgtatgttagaaacc
gtgttaaatcacgaaacagaagcagccttgctttttactcaacaagaacccaaagcatta
actaccattgatattttaaatggtggccgtcaagcattagaacaggcgaatattgccttg
ggtttagcgttggcagatgatgagatggattatttagtggaaagttttactgccttaaag
cgtaatccacaggatgtggagctttatatgtttgcacaagcgaattcagagcattgtcgc
cataaaatttttaatgccgattggattattgatggcaaaaaacaggataaatcgctgttt
aaaatgatcaaaaatacctttgagaaaacgcctgattttgtgctttctgcttataaagat
aatgctgcagtaatggaaggttcgaaagtcgggcgttggtttcctgatcctgatggacaa
tatcgtgttcatcaagaagatgctcacattttaatgaaagtggaaacacataaccatccc
acagcaatttcgccatttcctggtgctgcaacaggctctggcggggagattcgtgatgaa
ggggcaacggggcgtggggcaaaacccaaagcaggtttaacaggtttctcggtgtctaac
ctcgttattccaaactttgaacaaccttgggaaaatccattgtctaaaccaaatcgcatt
gcttctgccttggatattatgatagatgcgcctttaggtagtgcggcatttaataatgaa
tttggtcgcccagcattattaggttatttccgtacttatgaagaaaaagtaaatagtttt
gcaggaaaagaagtgcgcggttatcacaagccgattatgttagcgggaggaatcggtaat
attcgtggcgaacaggttcaaaaaggcgaaattccagtcggtgctaaattgatcgttttg
ggtggggcagcaatgaacattggtttaggtggtggtgctgcttcttcgatggacagtggt
aaatcaaaagaagatttagattttgcttctgttcaacgtgaaaatccggaaatggaacgc
cgctgccaagaagttattgaccgctgttggcaattaggcgaagaaaatccaatcctgttt
attcacgatgtgggtgcgggtggtttatctaatgcaatgcctgaattggtacacgatggc
aagcgtggaggaaaattcgatctgcgttctattctttgtgatgaaaaaggtatgtcgcca
ttggaaatttggtgtaatgaatcgcaagaacgttatgtattagccgttgcgccagaaaac
ctcgaattatttaccgcactttgtgagcgtgaacgtgccccttttgcagtgattggcgaa
gcaacacaagcagaacatttaatcttgcacgatagtcatttcgataataatccaattgat
ttaccaatgaatgtgttattaggcaaaacgccgaaaatgacgcgtgaagttttgtcaaaa
acagtagaaaatcaatcacttaaaacagaaggtattcaattaaaagaagcattccatcgt
gtattacgtttacccgttgttgcagaaaaaactttcttaattactattggcgaccgttct
gtaacaggtatggtggcacgagatcaaatggtgggtccttggcaaatccccgtgtctgat
gtggctgttactactgcttcactggatagctaccacggcgaagcaatggcaatgggcgaa
cgctctccagttgccttgctaaatttctcggcttcggcacgcttagctgtggcggaggcg
attactaacattgctggcacccacattggcgagatgaaacgtattaaactttctgccaac
tggatgagtgcagcaggtcacacaggcgaagatgctggactttatgaagcagtaaaagct
gtgggcgaagaactttgtcctgcgttaggcttaactattcctgtgggtaaagactcaatg
tcgatgaaaaccacttggatcgataatggcgaacaaaaatcagtgaccgccccactttca
ttagtaatttccgcttttgctcgtgtagaagatgtacgtaaaacgcttacgccacaactt
cgtaccgacaaaggtttatcgagtttattgctaattgatttaggcgaagggcataatcga
ttaggtgcgactgcacttgctcaagtgtacaaacagttaggagacaagcctgccgatgtg
gtaaaggttcaacgcttaaaagatttttacaatgcaatgcaaactttagtggcagaagat
aaattgttggcttatcacgaccgttcggacggcggtttaatcacaactcttgcagaaatg
gcgtttgcagggcattgtggggtagaagttgatatttcagccttaggcgacaatgattta
gcggtattatttaacgaagaattgggagcggttatccaagttaccgatagtcaattagaa
agtgtacgtgaggtgttgaaagctcacaatttgcttggtattactcaccaattaggtacg
gtaactgctgatgatcgctttgagatcagccgcggcagccataaattattcagcgaaaaa
cgctctgaattacgtagtatttgggcagaattaacttaccaaatgcaacgcttacgcgat
aatccagagtgtgctgagcaagagtttgaagctaagaaaaaccctgacgacaaaggctta
tccgcatttttgacttacgatgtgaatgaagatattactgcgccatttatcaataaaggt
gtaaaaccaaccattgcaattttacgtgaacaaggtgtaaatagtcattatgaaatggca
gcagcgtttgatcgtgcaggctttaatgcaattgacgtgcatatgtctgatttaatgatt
ggtcgtcgtaatttagccgaattcaatgcaatggttgcttgtggcggtttctcttacggc
gatgtgcttggcgcagggggcggttgggcaaaatccatcttatttaacccgaaattacac
gagcaattcagccagttttttatcaatccaaacacactgaccttaggcgtatgtaacggt
tgtcaaatgatctctaacttggcggaaattatcccaggtacagaaaactggccgcatttt
gtacgcaacaaatctgaacgctttgaagcgcgtgtgagtttagtgaaaattaatgaagtg
gattcagtttggtttgcaggaatggctggctcacatatgcccattgcggtttctcacggg
gaaggacaagttaagtttaaatcagttgaacagtttgcaggcttaaaagcacaaggcatc
attgccgcacaatatattgacaacaacggtagccccactgaactatatccagccaatccg
aatggttctgcggagggcattactgcaattacaaatcttgatgggcgagttgctattatg
atgccacaccctgaacgtgtgttccgtgctgtgagtaactcttggcacccagaaaactgg
acagaagacggtgcgtggatgagattattcagaaatgcaagaatggtattttaa
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