Haemophilus influenzae C486: NTHIC486_01608
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Entry
NTHIC486_01608 CDS
T03721
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hic
Haemophilus influenzae C486
Pathway
hic00300
Lysine biosynthesis
hic00550
Peptidoglycan biosynthesis
hic01100
Metabolic pathways
hic01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hic00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NTHIC486_01608 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NTHIC486_01608 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NTHIC486_01608 (murF)
Enzymes [BR:
hic01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NTHIC486_01608 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Beta-prop_FAM234A_B
Motif
Other DBs
NCBI-ProteinID:
AJO90287
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Position
complement(1658895..1660268)
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AA seq
457 aa
AA seq
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MIKLSTVQLAQILQAKLIGDENVQVEEINTDTRKSVSNSLFFALKGEKFDAHQYLDQAVS
QGALALVVQQENSSISVPQLVVKDTRIALGELAKWLREKINPRTVAMTGSSGKTTVKEMT
ASILQHTAADSEAVLFTNGNFNNDIGVPLTLLRLTEKHRFAVIELGANHQNEINYTTKLV
QPNAALINNIAPAHLEGFGSLVGVVQAKGEIYRGLTKNGVAIINAEHNHLDIWQKEISNH
AIQYFNGKDYSVKNVQGNEQGSTFTLVSPQGEIDISLPYLGEHNVKNALAATALAMNVGA
TLADVKAGLEQRSQVKGRLFPIQVTPNLLLLDDTYNANKDSLCAAIDVLKSYDAFLILCV
ADMKELGENSLAIHREVGQYINLVNLDLVCSYGNESAVISEAVLGKHFTDKTEMVDFLVP
LIENQLQQNKKVVVLGKGSRSMKMEDVIYSLKDKIKC
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgattaaactctctactgtacaacttgcacagattcttcaagctaaattaattggcgat
gaaaatgtgcaagttgaagaaattaatacagatactcgaaaaagcgtatcaaatagctta
ttttttgctttaaaaggcgaaaaatttgatgctcatcaatatcttgatcaagcggtgtca
cagggtgcgcttgcgcttgttgttcagcaagaaaattcatccatttctgttccacaattg
gtggttaaggatacccgtattgccttgggtgaacttgcaaaatggttacgtgagaaaatt
aatccacgtactgtggcgatgaccggctcttctggtaaaaccacggtaaaagaaatgacg
gcaagtattttgcaacataccgcagcagattcagaagcggtactttttaccaatggtaac
ttcaataacgatataggtgtgcctttaactctacttcgcttaacagaaaaacatcgtttt
gctgtgattgaacttggtgcaaatcatcaaaatgaaatcaattacaccacaaaattagtt
caacctaatgccgcattgattaataatattgcgcccgcacatttagaggggtttggttct
ttagtgggagttgttcaagcaaaaggcgagatttatcgaggtttaacaaaaaatggtgtg
gcgattatcaatgctgaacataatcacttagatatttggcaaaaagaaatcagcaatcac
gccattcaatatttcaacggcaaggattattccgtcaaaaatgttcaaggtaacgaacaa
ggttcaacctttacgttagtttctccgcaaggcgaaattgacatcagcttgccttatctt
ggagagcataatgtaaaaaatgctttagctgctaccgcactagcgatgaatgttggtgct
acgcttgccgatgtcaaagctggattagaacaacgttcacaagtgaaagggcgtttattt
cctattcaagtaacgcctaatttattgttattagatgatacttataacgcaaataaagat
tctctctgtgcggctattgatgtcctaaaaagttatgatgctttccttattctatgtgtc
gcagatatgaaagaattgggcgaaaattctctcgctattcatcgtgaagttggacaatat
attaatttggtaaatttagatttagtgtgttcttatggcaatgaaagtgcggttatttct
gaggctgttttgggcaagcattttacggataaaactgaaatggtggatttcttagttcca
cttattgaaaaccaattacaacaaaataaaaaagttgtggtgctaggaaaaggctcacgc
tcaatgaaaatggaagatgtgatctattcattaaaggataaaattaaatgttag
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