Haemophilus influenzae Hi375: NF38_08465
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Entry
NF38_08465 CDS
T03485
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hih
Haemophilus influenzae Hi375
Pathway
hih00300
Lysine biosynthesis
hih00550
Peptidoglycan biosynthesis
hih01100
Metabolic pathways
hih01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hih00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NF38_08465 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NF38_08465 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NF38_08465 (murF)
Enzymes [BR:
hih01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NF38_08465 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Beta-prop_FAM234A_B
Motif
Other DBs
NCBI-ProteinID:
AIT68214
UniProt:
A0A2R3GIH8
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Position
complement(1728442..1729815)
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AA seq
457 aa
AA seq
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MIKLSTVQLAQILQAKLIGDENVQVEEINTDTRKSVSNSLFFALKGEKFDAHQYLDQAVS
QGALALVVQQENSSILVPQLVVKDTRIALGELAKWLREKINPRTVAMTGSSGKTTVKEMT
ASILQHTAADSEAVLFTNGNFNNDIGVPLTLLRLTEKHRFAVIELGANHQNEINYTTKLV
QPNAALINNIAPAHLEGFGSLAGVVQAKGEIYRGLTKNGVAIINAEHNHLDIWQKEISNH
AIQYFNGKDYSVKNVQGNEQGSTFTLVSPQGEIDISLPYLGEHNVKNALAATALAMNVGA
TLADVKAGLEQRSQVKGRLFPIQVTPNLLLLDDTYNANKDSLCAAIDVLKSYDAFLILCV
ADMKELGENSLAIHREVGQYVNLVNLDLVCSYGNESAVISEAVLGKHFTDKTEMVDFLVP
LIENQLQQNKKVVVLGKGSRSMKMEDVIYSLKDKIKC
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgattaaactctctactgtacaacttgcacagattcttcaagctaaattaattggcgat
gaaaatgtgcaagttgaagaaattaatacggatactcgaaaaagcgtatcaaatagctta
ttttttgctttaaaaggcgaaaaatttgatgctcatcaatatcttgatcaagcggtgtca
cagggtgcgcttgcgcttgttgttcagcaagaaaactcgtctattttagttcctcaactt
gtggttaaagacactcgtattgctttgggcgagcttgcaaaatggttacgcgagaaaatt
aatccgcgtactgtggcgatgaccggctcttctggaaaaaccacagtaaaagaaatgaca
gcaagtattttgcagcataccgcagcagattcagaagcggtactttttaccaatggtaac
ttcaataacgatataggtgtgcctttaactctgcttcgcttaacagaaaaacatcgtttt
gctgtgattgaacttggtgcaaatcatcaaaatgaaatcaattacaccacaaaattagtt
caacctaatgccgcattgattaataatattgcgcccgcacatttagaggggtttggttct
ttagcgggagttgttcaagcaaaaggcgagatttatcgaggtttaacaaaaaatggtgtg
gcgattatcaatgctgaacataatcacttagatatttggcaaaaagaaattagtaatcac
gccattcaatatttcaacggcaaggactattccgtcaaaaatgttcaaggtaacgaacaa
ggttcaacctttacgttagtttctccgcaaggcgaaattgatattagtttaccttatctt
ggagagcataatgtaaaaaatgctttagctgctaccgcactagcgatgaatgttggtgct
acgcttgccgatgtcaaagctggattagaacaacgttcacaagtgaaagggcgtttattt
cctattcaagtaacgcctaatttattgttattagatgatacttataacgcaaataaagat
tctctctgtgcggctattgatgtcctaaaaagttatgatgctttccttattctatgtgtc
gcagatatgaaagaattgggcgaaaattctctcgctattcatcgtgaagttggacaatat
gttaatttggtaaatttagatttggtgtgttcttatggcaatgaaagtgcggttatttct
gaggctgttttgggtaagcattttacggataaaactgaaatggtggatttcttagttcca
cttattgaaaaccaattacaacaaaataaaaaagttgtggtgctgggaaaaggctcacgc
tcaatgaaaatggaagatgtgatctattcattaaaggataaaattaaatgttag
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