Haemophilus influenzae PittEE (nontypeable): CGSHiEE_02840
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Entry
CGSHiEE_02840 CDS
T00543
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homeserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
hip
Haemophilus influenzae PittEE (nontypeable)
Pathway
hip00260
Glycine, serine and threonine metabolism
hip00261
Monobactam biosynthesis
hip00270
Cysteine and methionine metabolism
hip00300
Lysine biosynthesis
hip01100
Metabolic pathways
hip01110
Biosynthesis of secondary metabolites
hip01120
Microbial metabolism in diverse environments
hip01230
Biosynthesis of amino acids
Module
hip_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
hip_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
hip00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
CGSHiEE_02840 (thrA)
00270 Cysteine and methionine metabolism
CGSHiEE_02840 (thrA)
00300 Lysine biosynthesis
CGSHiEE_02840 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
CGSHiEE_02840 (thrA)
Enzymes [BR:
hip01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
CGSHiEE_02840 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
CGSHiEE_02840 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
ABQ98004
LinkDB
All DBs
Position
571007..573454
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AA seq
815 aa
AA seq
DB search
MRVLKFGGTSLANPERFSQAAKLIEQAHLEEQAAGVLSAPAKITNHLVALSEKAALNQST
DTHFNEAIEIFYNIINGLHAENNQFDLNGTKALIDAEFAQIKGLLEEIRQAGKVEDAVKA
TIDCRGEKLSIAMMKAWFEARGYSVHIVDPVKQLLAKGGYLESSVEIEESTKRVDAASIA
KDKVVLMAGFTAGNEKGELVLLGRNGSDYSAACLAACLGASVCEIWTDVDGVYTCDPRLV
PDARLLPTLSYREAMELSYFGAKVIHPRTIGPLLPQNIPCVIKNTGNPSAPGSIIDGNVK
SESLQVKGITNLDNLAMFNVSGPGMQGMVGMASRVFSAMSGAGISVILITQSSSEYSISF
CVPVKSAEVAKTVLETEFANELNEHQLESIEVIKDLSIISVVGDGMKQAKGIAARFFSAL
AQANISIVAIAQGSSERSISAVVPQNKAIEAVKATHQALFNNKKVVDMFLVGVGGVGGEL
IEQVKRQKEYLAKKNVEIRVCAIANSNRMLLDENGLNLEDWKNDLENATQPSDFDVLLSF
IKLHHVVNPVFVDCTSAESVAGLYARALKEGFHVVTPNKKANTRELVYYNELRQNAQASQ
HKFLYETNVGAGLPVIENLQNLLAAGDELEYFEGILSGSLSFIFGKLEEGLSLSEVTALA
REKGFTEPDPRDDLSGQDVARKLLILAREAGIELELSDVEVEGVLPKGFSDGKSADEFMA
MLPQLDEEFKTRVATAKAEGKVLRYVGKISEGKCKVSIVAVDLNNPLYKVKDGENALAFY
TRYYQPIPLLLRGYGAGNAVTAAGIFADILRTLQH
NT seq
2448 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgtacttaaatttggcggcacttcgcttgcaaatccggaacgtttttcccaagcg
gcgaaattgatcgagcaagctcatttagaagagcaggctgcaggtgttttatcagcacca
gccaaaataaccaaccatctcgtcgccctttctgaaaaagctgcattaaatcaatcaacc
gatacgcatttcaacgaagcaatcgaaattttctataacatcattaatggcttacatgcc
gaaaataatcaattcgacttaaatggcaccaaggcacttattgatgctgaatttgctcaa
atcaaaggattattagaagaaattcgtcaggcaggaaaagtagaagatgcagttaaagcg
accattgattgccgtggggaaaaactttctattgcaatgatgaaagcttggtttgaagca
cgtggctatagcgtacatattgtggatccagtcaagcaattattagcaaaaggcggttat
cttgagtcttcagttgaaattgaagaatcaacaaaacgtgttgatgcagcaagtattgca
aaagataaagtggtgctgatggcaggttttactgcgggtaatgaaaaaggcgagttggta
ttgctcggtcgtaatggctcagactattctgcagcctgtttagccgcttgtttaggcgca
agtgtatgcgaaatttggaccgatgtggacggcgtttatacttgcgatccgcgtttagtg
cctgatgcacgtttattaccaacgctttcttatcgtgaagcgatggaactctcttatttc
ggtgcgaaagtgattcatcctcgtacgattgggccattgttgccacaaaatattccttgt
gtcattaaaaatacaggaaatccttctgcgccaggttcgattattgatggcaatgtgaaa
tcagaaagtttgcaagttaaaggtatcactaacttagacaatttggcgatgtttaatgtg
tcaggccctggtatgcaaggtatggtaggcatggcatctcgcgtattttcagccatgtca
ggtgcaggcatttcagttattttaattactcagtcttcgtctgaatatagtattagtttc
tgtgtgcctgtgaaatctgcagaagtagcgaaaaccgtactagaaacggagtttgctaat
gaattaaatgaacatcaattagaatcaattgaagtgattaaagatttatccattatttct
gttgtgggcgatggaatgaagcaagcgaaaggcattgctgctcgtttcttctcggcatta
gcgcaggcaaacattagcattgtggcgattgcacaaggatctagcgaacgttcaatttct
gcggttgtgccgcaaaataaagccattgaagcggtgaaggctacccatcaggcgcttttc
aataataaaaaagtcgtggatatgtttttagtgggcgttggcggagtaggcggagaatta
attgagcaggtaaagcgtcaaaaggagtatctagcaaagaagaatgttgaaattcgagtt
tgtgctattgcgaattccaaccgtatgttgcttgatgaaaatggattaaatttagaggat
tggaaaaacgatttagaaaatgcgactcagccatcagattttgatgtattgctttctttc
attaaattacatcatgtggtgaatccagtatttgtagattgtacttcagccgaatctgta
gcagggctttatgctcgtgcgttaaaagaaggtttccatgtggttacgccaaacaaaaaa
gcgaatacacgagaattagtttattacaatgagttacgccaaaatgcccaagcaagccag
cataaatttttatatgaaaccaatgtaggtgcgggcttgccagttattgaaaatctccaa
aacttacttgcagcaggtgatgagcttgaatattttgaagggattttatctggctcgctt
tcctttatttttggtaagttggaagaaggactttctctttcagaagtaaccgcacttgcg
cgtgaaaaaggctttactgagccagatcctcgagatgatctttctggacaagatgtagca
cgcaaattattaattcttgctcgtgaagcgggaattgaacttgaactttcagatgttgaa
gttgaaggtgtattgccgaaaggcttctccgatggaaaatctgcagatgagtttatggca
atgttgccacagcttgacgaggagtttaaaactcgcgttgccacagctaaagcagaaggc
aaagtattgcgttatgttggaaaaattagtgaaggaaaatgcaaagtatccatcgttgcg
gtagatctgaataatccactttataaagtgaaagatggtgaaaatgccttggcattttat
actcgttattatcaaccgattccacttttattacgtggttatggcgcaggtaatgcagtt
actgcggcaggtatctttgcagatattttaagaacattacaacattaa
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