Haemophilus influenzae PittEE (nontypeable): CGSHiEE_07035
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Entry
CGSHiEE_07035 CDS
T00543
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
hip
Haemophilus influenzae PittEE (nontypeable)
Pathway
hip00290
Valine, leucine and isoleucine biosynthesis
hip00620
Pyruvate metabolism
hip01100
Metabolic pathways
hip01110
Biosynthesis of secondary metabolites
hip01210
2-Oxocarboxylic acid metabolism
hip01230
Biosynthesis of amino acids
Module
hip_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hip00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CGSHiEE_07035
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CGSHiEE_07035
Enzymes [BR:
hip01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CGSHiEE_07035
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
NAD_binding_10
RdfA
Motif
Other DBs
NCBI-ProteinID:
ABQ98736
UniProt:
A5UD85
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All DBs
Position
complement(1401630..1403177)
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AA seq
515 aa
AA seq
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MTDRVIIFDTTLRDGEQALKASLTVKEKLQIALALERLGVDVMEVGFPVSSQGDFESVQT
IARHIKNARVTALSRAVDKDIDAAYEALKVAEAFRIHTFIASSALHVEAKLKRSFDDVVG
MAVAAVKRARNYTDDVEFSCEDAGRTGIDNICRIVEAAINAGATTVNIPDTVGFCLPNEY
GNIIAQVRNRVPNIDKAVISVHCHNDLGMATANSLTAVQNGARQIECTINGIGERAGNTS
LEEVVMAMKVRQDFMGVDTRINTQEIHRVSQMVSQLCNMPIQPNKAIVGSNAFAHSSGIH
QDGMLKNKNTYEIMSPETIGLKKEKLNLTARSGRAAVKGHMADMGYNEQDYDLDKLYDAF
LKLADKKGQVFDYDLEALAFIDMQQGDEDRLVLDKLSAHSTKEYPATAFVQLKLDGNKLI
TSSIGGNGPVDAVYNAILNLTGLEIKMSHYNLTAKGEGAEALGQVDIVVEHKGRKFHGVG
LATDIVESSALALVHAINAIYRAHKVADIKNHKHH
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgacagatcgcgttattatttttgataccaccttgcgtgatggggagcaggcgttaaaa
gcaagtttgacggtaaaagaaaaattacagatcgctttagcacttgaacgcttaggtgtg
gatgtaatggaagtagggtttcctgtttcttctcaaggggattttgaatctgttcaaacc
attgcgcgccatattaaaaacgctcgtgttaccgcgttatctcgagccgtagataaagac
attgatgccgcatatgaagccttaaaagtggcagaagcattccgtattcatacgtttatt
gcaagttccgcattgcacgttgaagcgaaattaaaacgttcttttgatgatgtggtagga
atggcagttgcagcagtgaaacgcgcacgtaattatacggatgatgttgagttctcttgc
gaagatgcaggtcgtacaggcattgataatatctgtcgtattgttgaagcggcaattaat
gcgggggcaactacggtaaatattcccgatacagtcggtttttgcttaccaaatgaatac
ggcaatattattgctcaagtgcgtaatcgcgtgccgaatattgataaagcagtgatttcc
gtgcattgccataatgacttaggtatggcaaccgctaattctttaacggcagtacaaaat
ggtgcgcgccaaattgaatgtaccattaatggaattggtgaacgtgcaggcaatacttcc
cttgaagaagtggtgatggcaatgaaagttcgtcaggattttatgggcgtggatactcgt
attaatacccaagaaattcatcgcgtgagtcaaatggttagccaactttgcaatatgcca
attcaaccgaataaagccattgtgggttcaaatgcttttgcccattcttctggtattcat
caagatggtatgttgaaaaacaaaaatacttacgaaattatgtctccagaaaccatcggt
ttgaaaaaagaaaaattgaatttaaccgcacgttctggtcgtgcagctgtgaaaggtcat
atggcagatatgggctataacgaacaagattacgatttggataaattgtatgacgcgttc
ttaaaattggcggataaaaaaggtcaagtgttcgattatgatttggaggccttggcgttt
atcgatatgcaacaaggggatgaagatcgtttggtattagataaactttctgcgcattca
accaaagaatatccagccacagcctttgttcaattgaaattagatggtaataaattaatc
acttcgtcaattggtggcaatggcccagtggatgcggtttataacgccatcttaaattta
acgggtttagaaatcaaaatgtctcactataacttaactgctaaaggcgagggcgcagaa
gcattagggcaagtggatattgtggtggaacacaaagggcgtaaattccacggtgtcggt
ttagcgacagacattgttgaatcttccgcacttgctttagtccacgccatcaatgccatt
tatcgcgcgcataaagtggcagatattaagaatcataaacatcattaa
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