Haemophilus influenzae 86-028NP (nontypeable): NTHI0167
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Entry
NTHI0167 CDS
T00248
Symbol
thrA
Name
(GenBank) aspartokinase/homoserine dehydrogenase
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
hit
Haemophilus influenzae 86-028NP (nontypeable)
Pathway
hit00260
Glycine, serine and threonine metabolism
hit00261
Monobactam biosynthesis
hit00270
Cysteine and methionine metabolism
hit00300
Lysine biosynthesis
hit01100
Metabolic pathways
hit01110
Biosynthesis of secondary metabolites
hit01120
Microbial metabolism in diverse environments
hit01230
Biosynthesis of amino acids
Module
hit_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
hit00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
NTHI0167 (thrA)
00270 Cysteine and methionine metabolism
NTHI0167 (thrA)
00300 Lysine biosynthesis
NTHI0167 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
NTHI0167 (thrA)
Enzymes [BR:
hit01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
NTHI0167 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
NTHI0167 (thrA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AAX87152
UniProt:
Q4QP95
LinkDB
All DBs
Position
complement(151293..153740)
Genome browser
AA seq
815 aa
AA seq
DB search
MRVLKFGGTSLANPERFSQAAKLIEQAHLEEQAAGVLSAPAKITNHLVALSEKAALNQST
DTHFNEAIEIFYNIINGLHAENNQFDLNGTKALIDAEFAQIKGLLEEIRQAGKVEDAVKA
TIDCRGEKLSIAMMKAWFEARGYSVHIVDPVKQLLAKGGYLESSVEIEESTKRVDAANIA
KDKVVLMAGFTAGNEKGELVLLGRNGSDYSAACLAACLGASVCEIWTDVDGVYTCDPRLV
PDARLLPTLSYREAMELSYFGAKVIHPRTIGPLLPQNIPCVIKNTGNPSAPGSIIDGNVK
SESLQVKGITNLDNLAMFNVSGPGMQGMVGMASRVFSAMSGAGISVILITQSSSEYSISF
CVPVKSAEVAKTVLETEFANELNEHQLESIEVIKDLSIISVVGDGMKQAKGIAARFFSAL
AQANISIVAIAQGSSERSISAVVPQNKAIEAVKATHQALFNNKKVVDMFLVGVGGVGGEL
IEQVKRQKEYLAKKNVEIRVCAIANSNRMLLDENGLNLEDWKNDLENATQPSDFDVLLSF
IKLHHVVNPVFVDCTSAESVAGLYARALKEGFHVVTPNKKANTRELVYYNELRQNAQASQ
HKFLYETNVGAGLPVIENLQNLLAAGDELEYFEGILSGSLSFIFGKLEEGLSLSEVTALA
REKGFTEPDPRDDLSGQDVARKLLILAREAGIELELSDVEVEGVLPKGFSEGKSADEFMA
MLPQLDKEFKTRVATAKAEGKVLRYVGKISEGKCKVSIVAVDLNNPLYKVKDGENALAFY
TRYYQPIPLLLRGYGAGNAVTAAGIFADILRTLQH
NT seq
2448 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgtacttaaatttggcggcacttcgcttgcaaatccggaacgtttttcccaagcg
gcgaaattgatcgaacaagctcatttagaagagcaggctgcaggtgttttatctgcacca
gccaaaataaccaaccatctcgtcgccctttctgaaaaagctgcattaaatcaatcaacc
gatacgcatttcaacgaagcaatcgaaattttctataacatcatcaatggcttacatgcc
gaaaataatcaattcgacttaaatggcaccaaggcacttattgatgctgaatttgctcaa
atcaaaggattattagaagaaattcgtcaggcaggaaaagtagaagatgcagttaaagcg
accattgattgccgtggggaaaaactttctattgcaatgatgaaagcttggtttgaagcg
cgtggctatagcgtacatattgtggatcctgtcaaacaattattggcaaaaggcggttat
cttgaatcttctgttgaaattgaagaatcaacaaaacgtgttgatgcagcaaatatcgca
aaagataaagtggtgctgatggcaggttttactgcgggtaatgaaaaaggcgagttggta
ttgctcggtcgtaatggctcagactattctgccgcctgtttagccgcttgtttaggcgca
agtgtatgcgaaatttggaccgatgtggacggcgtttatacttgcgatccgcgtttagtg
cctgatgcacgtttattaccaacgctttcttatcgtgaagcgatggaactctcttatttc
ggtgcgaaagtgattcatcctcgtacgattgggccattgttgccacaaaatattccttgt
gtcattaaaaatacaggaaatccttctgcgccaggttcgattattgatggcaatgtgaaa
tcagaaagtttgcaagttaaaggtatcactaacttagacaatttggcgatgtttaatgtg
tcaggccccggtatgcaaggtatggtaggcatggcatctcgcgtattttcagccatgtca
ggcgcaggcatttcagttattttaattactcagtcttcgtctgaatatagtattagtttc
tgtgtgcctgtgaaatctgcagaagtagcgaaaaccgtactagaaacggagtttgctaat
gaattaaatgaacatcaattagaatcaattgaagtgattaaagatttatccattatttct
gttgtgggcgatggaatgaagcaagcgaaaggcattgctgctcgtttcttctcggcatta
gcgcaggcaaacattagcattgtggcgattgcacaaggatctagcgaacgttcaatttct
gcggttgtgccgcaaaataaagccattgaagcggtgaaggctacccatcaggcgcttttc
aataataaaaaagtcgtggatatgtttttagtgggcgttggtggagtaggcggagaatta
atagagcaggtaaagcgtcaaaaggagtatctagcaaagaagaatgttgaaattcgagtt
tgtgctattgcgaattccaaccgtatgttgcttgatgaaaatggattaaatttagaggat
tggaaaaacgatttagaaaatgcgactcagccatcagattttgatgtattgctttctttc
attaaattacatcatgtggtgaatccagtatttgtagattgtacttcagccgaatctgta
gcagggctttatgctcgtgcgttaaaagaaggtttccatgtggttacgccaaacaaaaaa
gcgaatacacgagaattagtttattacaatgagttacgccaaaatgcccaagcaagccag
cataaatttttatatgaaaccaatgtaggtgcgggcttgccagttattgaaaatctccaa
aacttacttgcagcaggtgatgagcttgaatattttgaagggattttatctggctcgctt
tcctttatttttggtaagttggaagaaggactttctctttcagaagtaaccgcacttgcg
cgtgaaaaaggctttactgagccagatcctcgagatgatctttctggacaagatgtagcg
cgcaaattattaattcttgctcgtgaagcgggaattgaacttgaactttcagatgttgaa
gttgaaggtgtattgccgaaaggcttctctgaaggaaaatctgcagatgagtttatggca
atgttgccacagcttgacaaggagtttaaaactcgcgttgccacagctaaagcagaaggc
aaagtattgcgttatgttggaaaaattagtgaaggaaaatgcaaagtatccatcgttgcg
gtagatctgaataatccactttataaagtgaaagatggtgaaaatgccttggcattttat
actcgttattatcaaccgattccacttttattacgtggttatggcgcaggtaatgcagtt
actgcggcaggtatctttgcagatattttaagaacattacaacattaa
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