Haemophilus influenzae 86-028NP (nontypeable): NTHI0909
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Entry
NTHI0909 CDS
T00248
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
hit
Haemophilus influenzae 86-028NP (nontypeable)
Pathway
hit00230
Purine metabolism
hit01100
Metabolic pathways
hit01110
Biosynthesis of secondary metabolites
Module
hit_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
hit00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NTHI0909 (purL)
Enzymes [BR:
hit01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NTHI0909 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
DUF7483
Motif
Other DBs
NCBI-ProteinID:
AAX87801
UniProt:
Q4QME6
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All DBs
Position
879318..883280
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AA seq
1320 aa
AA seq
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MQTFALFVIIRLFFYFSFIRNCNMTVKTFRGSPALSEFRLTQLQQKCQQYQLPITSVYAE
YLHFVEQKTSLVEDEIVKLQALLHYGSMFSELKPAGYCLIVTPRVGTISSWSSKATDIAH
NCGLSKVNRIERGIAYYFNIERDLTEAELATLKDLLHDRMLETVLNHETEAALLFTQQEP
KALTTIDILNGGRQALERANIALGLALADDEMDYLVESFTALKRNPQDVELYMFAQANSE
HCRHKIFNADWIIDGKKQDKSLFKMIKNTFEQTPDFVLSAYKDNAAVMEGSKVGRWFPDP
DGQYRVHQEDAHILMKVETHNHPTAISPFPGAATGSGGEIRDEGATGRGAKPKAGLTGFS
VSNLVIPNFEQPWENPLSKPNRIASALDIMIDAPLGSAAFNNEFGRPALLGYFRTYEEKV
NSFAGKEVRGYHKPIMLAGGIGNIRGEQVQKGEIPIGAKLIVLGGAAMNIGLGGGAASSM
DSGKSKEDLDFASVQRENPEMERRCQEVIDRCWQLGEENPILFIHDVGAGGLSNAMPELV
HDGRRGGKFDLRSILCDEKGMSPLEIWCNESQERYVLAVAPENLELFTALCERERAPFAV
IGEATQAEHLILHDSHFDNNPIDLPMNVLLGKTPKMTREVLSKTVENQSLKTEGIQLKEA
FHRVLRLPVVAEKTFLITIGDRSVTGMVARDQMVGPWQIPVSDVAVTTASLDSYHGEAMA
MGERSPVALLNFSASARLAVAEAITNIAGTHIGEMKRIKLSANWMSAAGHTGEDAGLYEA
VKAVGEELCPALGLTIPVGKDSMSMKTTWIDNGEQKSVTAPLSLVISAFARVEDVRKTLT
PQLRTDKGLSSLLLIDLGEGHNRLGATALAQVYKQLGDKPADVVKVQRLKDFYNAMQTLV
AEDKLLAYHDRSDGGLITTLAEMAFAGHCGVEVDISALGDNDLAVLFNEELGAVIQVADS
QLESVREVLKAHNLLGITHQLGTVTADDRFEISRGSHKLFSEKRSELRSIWAELTYQMQR
LRDNPECAEQEFEAKKNPDDKGLSAFLTYDVNEDITAPFINKGVKPTIAILREQGVNSHY
EMAAAFDRAGFNAIDVHMSDLMIGRRNLAEFNAMVACGGFSYGDVLGAGGGWAKSILFNP
KLHEQFSQFFINPNTLTLGVCNGCQMISNLAEIIPGTENWPHFVRNKSERFEARVSLVKI
NEVDSVWFAGMAGSHMPIAVSHGEGQVKFKSVEQFAGLKAQGIIAAQYIDNNGSPTELYP
ANPNGSAEGITAITNLDGRVAIMMPHPERVFRAVSNSWHPENWTEDGAWMRLFRNARMVF
NT seq
3963 nt
NT seq
+upstream
nt +downstream
nt
atgcaaacgtttgctttgttcgttataatacgtctgtttttttatttttcttttatacgg
aactgcaatatgactgtcaaaacctttcgtggctcgcctgctctttctgaatttcgttta
actcaacttcaacaaaaatgccagcaatatcaattgcctattacgtcagtttatgcagag
tatttgcattttgttgaacaaaaaacatcgcttgtagaagatgaaatcgttaaattacaa
gcattattgcattatgggtcaatgttttctgaactcaagcctgcaggatattgtttaatt
gtgactccacgagtggggacaatttcctcttggtcttcaaaagcgacagacatcgctcac
aattgtggtttgtcgaaggtaaatcgtattgaacgtggtatagcctattacttcaatatt
gagcgtgatttaaccgaagcagaattggctacgctgaaagatttattacacgaccgtatg
ttagaaaccgtgttaaatcacgaaacagaagcagccttgctttttactcaacaagaaccc
aaagcattaactaccattgatattttaaatggtggccgtcaagcattagaacgggcgaat
attgccttgggtttagcgttggcagatgatgagatggattatttagtggaaagttttact
gccttaaagcgtaatccacaggatgtggagctttatatgtttgcacaagcgaattcagag
cattgtcgccataaaatttttaatgccgattggattattgatggcaaaaaacaggataaa
tcgctgtttaaaatgatcaaaaatacctttgagcaaacgcctgattttgtgctttctgct
tataaagataatgctgcagtaatggaaggttcgaaagtcggccgttggtttcctgatcct
gatggacaatatcgtgttcatcaagaagatgcgcacattttaatgaaagtggaaacgcat
aaccatcccacagcaatttcgccatttcctggtgctgcaacaggctctggcggggagatt
cgtgatgaaggggcaacggggcgtggggcaaaacccaaagcaggtttaacaggtttctcg
gtgtctaacctcgttattccaaactttgaacaaccttgggaaaatccattgtctaaacca
aatcgcattgcttctgccttagatattatgatagatgcgcctttaggtagtgcggcattt
aataatgaatttggtcgcccagcattattaggttatttccgtacttatgaagaaaaagta
aatagttttgcaggaaaagaagtacgcggttatcacaagccgattatgttagcgggagga
atcggtaatattcgtggcgaacaggttcaaaaaggcgaaattccaatcggtgctaaattg
atcgtgttgggtggggcagcaatgaacatcggtttaggtggtggtgctgcttcttcgatg
gacagtggtaaatcaaaagaagatttagattttgcttctgttcaacgtgaaaatccggaa
atggaacgccgctgccaagaagttattgaccgctgttggcaattaggcgaagaaaatcca
atcctgtttattcacgatgtgggggcgggtggtttatctaatgcaatgcctgaattggta
catgatggcaggcgtggaggaaaattcgatctgcgttctattctttgtgatgaaaaaggt
atgtcgccattggaaatttggtgtaatgaatcgcaagaacgttatgtattagccgttgcg
ccagaaaacctcgaattatttaccgcactttgtgagcgtgaacgtgccccttttgcagtg
attggcgaagcaacacaagcagaacatttaatcttgcacgatagtcatttcgataataat
ccgattgatttaccaatgaatgtgttattaggcaaaacgccgaaaatgacgcgtgaggtt
ttatcaaaaacagtggaaaatcaatcacttaaaacagaaggtattcaattaaaagaagca
ttccatcgtgtattacgtttacccgttgttgcagaaaaaactttcttaattactattggt
gatcgctcggtaacaggaatggtagcccgtgatcaaatggtgggaccttggcaaattcct
gtatctgatgtggctgttactactgcttcactggatagctaccacggcgaagcaatggca
atgggcgaacgctctccagttgccttgctaaatttctcggcttcggcacgcttagctgtg
gcggaggcgattactaacattgctggcacccacattggcgagatgaaacgtattaaactt
tctgccaactggatgagtgcagcaggtcacacaggcgaagatgcgggactttatgaagca
gtaaaagctgtgggcgaagaactttgtcctgcgttaggtttaactattcctgtgggtaaa
gactcaatgtcgatgaaaaccacttggatcgataatggcgaacaaaaatcagtgactgcc
ccactttcattagtaatttccgcttttgctcgtgtagaagatgtacgtaaaacgcttacg
ccacaacttcgtaccgacaaaggtttatcgagtttattgctaattgatttaggcgaaggg
cataatcgattaggtgcgactgcacttgctcaagtgtacaaacagttaggagacaagcct
gccgatgtggtaaaggttcaacgcttaaaagatttttacaatgcaatgcaaactttagtg
gcagaagataaattgttggcttatcacgaccgttcggacggcggtttaatcacaactctt
gcagaaatggcgtttgcagggcattgtggggtagaagttgatatttcagctttaggcgac
aacgatttagcggtattatttaacgaagaactgggagcggttatccaagttgccgatagc
caattagaaagtgtacgtgaggtgttgaaagctcacaatttgcttggtattacccaccaa
ttaggtacggtaactgctgatgatcgctttgagatcagccgcggcagccataaattattc
agcgaaaaacgctctgaattacgtagtatttgggcagaattaacttaccaaatgcaacgc
ttacgcgataatccagagtgtgctgagcaagagtttgaagctaagaaaaaccctgacgac
aaaggcttatccgcatttttgacttacgatgtgaatgaagatattactgcgccatttatc
aataaaggtgtaaaaccaaccattgcaattttacgtgaacaaggtgtaaatagtcattat
gaaatggcagcagcgtttgatcgagcaggctttaatgcaattgacgtgcatatgtctgat
ttaatgattggtcgtcgtaatttagccgaattcaatgcaatggttgcttgtggcggtttc
tcttacggcgatgtgcttggcgcagggggcggttgggcaaaatccatcttatttaacccg
aaattacacgagcaattcagccagttttttatcaatccaaacacactgaccttaggcgta
tgtaacggttgtcaaatgatctctaacttggcggaaattatcccaggtacagaaaactgg
ccgcattttgtacgcaacaaatctgaacgctttgaagcgcgtgtgagtttagtgaaaatt
aatgaagtggattcagtttggtttgcaggaatggctggctcacatatgcccattgcggtt
tctcacggggaaggacaagttaagtttaaatcagttgaacagtttgcaggcttaaaagca
caaggcatcattgctgcacaatatattgacaacaacggtagccccaccgaactatatcct
gccaatccgaatggttctgcggagggcattactgcaattacaaatcttgatgggcgagtt
gctattatgatgccacaccctgaacgtgtgttccgtgctgtgagtaactcttggcaccca
gaaaactggacagaagacggtgcgtggatgagattattcagaaatgcaagaatggtattt
tag
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