Haemophilus influenzae 86-028NP (nontypeable): NTHI1160
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Entry
NTHI1160 CDS
T00248
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
hit
Haemophilus influenzae 86-028NP (nontypeable)
Pathway
hit00290
Valine, leucine and isoleucine biosynthesis
hit00620
Pyruvate metabolism
hit01100
Metabolic pathways
hit01110
Biosynthesis of secondary metabolites
hit01210
2-Oxocarboxylic acid metabolism
hit01230
Biosynthesis of amino acids
Module
hit_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hit00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
NTHI1160 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NTHI1160 (leuA)
Enzymes [BR:
hit01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
NTHI1160 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
NAD_binding_10
RdfA
Motif
Other DBs
NCBI-ProteinID:
AAX88023
UniProt:
Q4QLS4
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All DBs
Position
1100087..1101634
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AA seq
515 aa
AA seq
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MTDRVIIFDTTLRDGEQALKASLTVKEKLQIALALERLGVDVMEVGFPVSSQGDFESVQT
IARHIKNARVAALSRAVDKDIDAAYQALKVAEAFRIHTFIASSALHVEAKLKRSFDDVVG
MAVAAVKRARNYTDDVEFSCEDAGRTGIDNICRIVEAAINAGATTVNIPDTVGFCLPNEY
GNIIAQVRNRVPNIDKAVISVHCHNDLGMATANSLTAVQNGARQIECTINGIGERAGNTS
LEEVVMAMKVRQDFMGVDTRINTQEIHRVSQMVSQLCNMPIQPNKAIVGSNAFAHSSGIH
QDGMLKNKNTYEIMSPETIGLKKEKLNLTARSGRAAVKGHMADMGYNEQDYDLDKLYDAF
LKLADKKGQVFDYDLEALAFIDMQQGDEDRLVLDKLSAHSTKEYPATAFVQLKLDGEKLS
TSSIGGNGPVDAVYNAILNLTGLEIKMSHYNLTAKGEGAEALGQVDIVVEHKGRKFHGVG
LATDIVESSALALVHAINAIYRAHKVADIKSHKHH
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgacagatcgcgttattatttttgataccaccttgcgtgatggggaacaggcgttaaaa
gcaagtttgacggtaaaagaaaaattacagatcgctttagcacttgaacgcttaggtgtg
gatgtaatggaagtggggtttcccgtttcttctcaaggggattttgaatcggtacaaacc
attgcgcgccatatcaaaaacgctcgtgttgccgcgttatctcgagccgtagataaagac
attgatgccgcataccaagcattgaaagtggcagaagcattccgtattcatacttttatt
gcaagctcggcattacacgttgaagcgaaattaaaacgttcttttgatgatgtggtagga
atggcagttgcagcagtgaaacgcgcacgtaattatacggatgatgttgagttctcttgc
gaagatgcggggcgtacgggcattgacaatatctgtcgtattgtagaggcggcaattaat
gcaggtgcaactacagtaaacattccagataccgttggtttctgcttaccaaatgaatac
ggcaatattattgctcaagtgcgtaatcgcgtgccgaatatcgacaaagccgtgatttcc
gtgcattgccacaatgacttaggtatggcaaccgctaattctttaaccgctgtacaaaat
ggtgcacgccaaattgaatgtactattaatggaattggggaacgtgcgggcaatacttcc
cttgaagaagtggtaatggcaatgaaagtgcgtcaagatttcatgggcgtggatactcgt
attaatacccaagaaattcatcgcgtgagtcaaatggttagccagctttgcaatatgcca
attcagccgaataaagccattgtaggctcaaatgcttttgcccattcttctggtattcat
caagatggtatgttgaaaaacaaaaatacctacgaaattatgtctccagaaaccattggt
ttgaaaaaagaaaaattgaatttaactgcacgttctggtcgtgcggctgtgaaaggtcat
atggcggatatgggctacaacgaacaagattatgatttggataaattgtatgacgcgttc
ttaaaattggcggataaaaaaggtcaagtgtttgattatgatttggaagccttggcattt
atcgatatgcaacaaggggatgaagatcgtttggtattagataaactttctgcgcattca
accaaagaatatccagcaacagcctttgttcaattgaaattagatggcgaaaaattaagc
acttcgtcaattggtggtaacggcccagtagatgcggtttataacgccatcttaaattta
acaggcttagaaatcaaaatgtctcactataacttaaccgctaaaggcgagggcgcagaa
gcattagggcaagtggatattgtggtggaacacaaagggcgtaaattccacggtgttggt
ttagcaacagacatcgttgaatcttccgcacttgctttagtccacgctatcaatgccatt
tatcgcgcacataaagtggcagacattaaaagccataaacatcactaa
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