Haemophilus influenzae 86-028NP (nontypeable): NTHI1162
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Entry
NTHI1162 CDS
T00248
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
hit
Haemophilus influenzae 86-028NP (nontypeable)
Pathway
hit00290
Valine, leucine and isoleucine biosynthesis
hit00660
C5-Branched dibasic acid metabolism
hit01100
Metabolic pathways
hit01110
Biosynthesis of secondary metabolites
hit01210
2-Oxocarboxylic acid metabolism
hit01230
Biosynthesis of amino acids
Module
hit_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hit00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NTHI1162 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NTHI1162 (leuC)
Enzymes [BR:
hit01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
NTHI1162 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
NTHI1162 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AAX88025
UniProt:
Q4QLS2
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All DBs
Position
1103050..1104459
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AA seq
469 aa
AA seq
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MAKTLYEKLFDSHIVYEAEGETPILYINRHLIHEVTSPQAFDGLRVANRQVRQVNKTFGT
MDHSISTQVRDVNKLEGQAKIQVLELDKNTKATGIKLFDITTKEQGIVHVMGPEQGLTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQARAKSMKIEVRGKVASGITA
KDIILAIIGKTTMAGGTGHVVEFCGEAIRDLSMEGRMTVCNMAIEMGAKAGLIAPDETTF
AYLKDRPHAPKGKDWDDAVAYWKTLKSDDDAQFDTVVTLEAKDIAPQVTWGTNPGQVISV
NETIPNPQEMADPVQRASAEKALHYIGLEAGTNLKDIKVDQVFIGSCTNSRIEDLRAAAA
VMKGRKKADNVKRILVVPGSGLVKEQAEKEGLDKIFIAAGAEWRNPGCSMCLGMNDDRLG
EWERCASTSNRNFEGRQGRNGRTHLVSPAMAAAAGMFGKFVDIREVALN
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atggcaaaaacactttacgaaaaattatttgattcccacattgtttatgaagcagagggc
gaaacgccaattttgtatattaaccgtcatttgattcacgaagtaactagtccgcaggct
tttgatgggttacgcgtcgcaaatcgccaagtacgccaagtaaacaaaacttttggcaca
atggatcacagcatttctactcaagtacgagacgtcaataaacttgaaggtcaagcgaaa
attcaagtgttagaattggataaaaataccaaagcaacaggtattaaattatttgatata
acaaccaaagagcaaggcattgtacacgttatggggcctgaacaaggtttaaccttaccg
ggtatgacaattgtttgtggtgattcacacaccgcaacgcacggtgcatttggtgccttg
gcttttggtattggtacttctgaagtagaacacgtattagccactcaaactttaaaacag
gctcgagcaaaaagtatgaaaattgaagtgcgtggtaaagttgcatcaggtattacggca
aaagatattattcttgccattatcggtaaaaccactatggcaggcggaacaggacacgtt
gtagaattctgcggcgaagcgatccgagacctttctatggaggggcgtatgactgtatgt
aatatggcgattgaaatgggtgcaaaagcaggcttgattgcgccagacgaaaccacattt
gcatatttgaaagatcgtccacacgcaccgaaaggcaaagattgggatgatgccgtagct
tattggaaaaccttaaaatctgacgatgatgcacaatttgacactgtggtaacgctagaa
gcaaaagacatcgcaccacaagtcacttgggggacaaacccagggcaggtaatttctgtg
aatgaaactataccaaatccgcaagaaatggcagatcctgtacaacgtgcttcggcagaa
aaagccttacattatattggcttggaagctggcactaatttaaaagatattaaagttgat
caggtgttcatcggatcttgcaccaactcgcgtattgaagatttacgcgcagcagcggct
gtaatgaaaggtcgtaaaaaagcggataatgtaaaacgtattttagtagtaccaggttct
ggcttagtgaaagaacaagcggaaaaagagggcttggataaaatctttattgccgcaggt
gcagaatggcgtaatccaggttgttcaatgtgtttaggaatgaacgacgaccgtttaggc
gaatgggaacgttgtgcttccacgtcaaaccgtaactttgaggggcgtcaaggtcgtaat
gggcgtacccatttagtaagtcctgcaatggcggcagcagcaggaatgttcggtaaattt
gttgatattcgtgaagtggcattaaattaa
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