Haemophilus influenzae R2866 (nontypeable): R2866_0848
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Entry
R2866_0848 CDS
T01981
Symbol
folC
Name
(GenBank) Bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
hiz
Haemophilus influenzae R2866 (nontypeable)
Pathway
hiz00790
Folate biosynthesis
hiz01100
Metabolic pathways
hiz01240
Biosynthesis of cofactors
Module
hiz_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
hiz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
R2866_0848 (folC)
Enzymes [BR:
hiz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
R2866_0848 (folC)
6.3.2.17 tetrahydrofolate synthase
R2866_0848 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
ADO80799
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Position
864969..866282
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AA seq
437 aa
AA seq
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MNNMQLKATSPLAEWLSYLEKSHFKPIDLGLDRIQSVAEKLDLLHPAPYVITVGGTNGKG
TTCRLLETILLNHGLRVGVYSSPHLLRYNERVRIQNQDLPDEAHTASFTFIDENKTESLT
YFEFSTLSALHLFKQAKLDVVILEVGLGGRLDATNIVDSHLAVITSIDIDHTDFLGDTRE
DIAFEKAGIFCENCPVVIGEPNVPQTMLDQAEKLHCQVARRDVDWLFEQNAENWQWQNKK
VRLENLPFCQIPLANAATALAAVQCLPFDISEQTLRKSLQEVELVGRFQAIKADKREKLA
DYLGVSVETLPIIIVDVGHNPHAAKYLSEKLTALKCNIEGKMIAVCGMLKDKDANGVFEH
LTPIIDEWHCVTLGGYRGQSGDELADKLKSHFPNIQATSDNSVMDGVCTALKSAVKNDAV
LVFGSFHTVAEFWAVVE
NT seq
1314 nt
NT seq
+upstream
nt +downstream
nt
atgaataatatgcaacttaaagccacttcgccactcgctgagtggctttcttatttagaa
aaaagccattttaaacctattgatcttggtttagatcgtattcaatccgtggcagaaaaa
ttggatttacttcatcccgccccttatgtgataactgtgggggggacgaatggtaaaggc
acgacttgtcgcttgttagaaacgattctgcttaatcacggattacgtgtaggcgtgtat
tcttcgccccatttattgcgttataacgagcgagtacgcattcaaaatcaagatttaccc
gatgaagcacacactgcctcttttacttttattgatgaaaacaaaacagaatcgctgact
tattttgaatttagcaccctttctgcattgcatttatttaagcaagcaaaattagatgtg
gtgattttagaagtggggttgggtggtcgtttagatgcgaccaatattgtggatagccat
cttgctgtgattactagcatcgatattgatcacaccgattttcttggggataccagagag
gatattgcttttgaaaaagcaggaattttctgcgaaaattgccctgtcgtgattggtgaa
cctaatgtgccgcaaacaatgttagatcaggctgaaaaattacattgccaagttgctcgt
cgtgatgtggattggttatttgagcaaaatgctgaaaattggcaatggcaaaataaaaaa
gtgcggttagaaaatttgccgttttgtcagattccattggcgaatgccgcaacggctctt
gctgctgttcaatgtttaccttttgatatttcagaacagactttgcgaaaatctttgcaa
gaggtagaactggttggtcgttttcaagcaataaaagcagataaacgtgaaaaattagcg
gattatcttggcgtatcagttgaaaccttgccaataattatcgttgatgtggggcataat
cctcatgctgcaaaatatttatctgaaaaattgaccgcacttaaatgcaacattgagggc
aaaatgattgccgtatgtgggatgctcaaagacaaagatgcaaatggggtatttgagcat
ttaacacctattattgatgaatggcattgtgtaaccttaggcggttatcgcgggcagtca
ggcgatgaattagctgataaactgaaaagtcatttcccaaatattcaagctacatcagat
aattctgttatggatggggtgtgtacagcacttaaaagtgcggtaaagaatgatgctgtt
ttagtctttggatctttccacaccgtagccgaattttgggctgtggtggaataa
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