Haemophilus influenzae R2866 (nontypeable): R2866_1644
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Entry
R2866_1644 CDS
T01981
Symbol
purL
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
hiz
Haemophilus influenzae R2866 (nontypeable)
Pathway
hiz00230
Purine metabolism
hiz01100
Metabolic pathways
hiz01110
Biosynthesis of secondary metabolites
Module
hiz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
hiz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
R2866_1644 (purL)
Enzymes [BR:
hiz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
R2866_1644 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
DUF7483
Motif
Other DBs
NCBI-ProteinID:
ADO81571
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Position
complement(1671892..1675854)
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AA seq
1320 aa
AA seq
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MQTFALFVIIRLFFYFSFIRNCNMTVKTFRGSPALSEFRLTQLQQKCQQYQLPITSVCAE
YLHFVEQKTSLVEDEIVKLQALLHYGSMFSELKPAGYCLIVTPRVGTISSWSSKATDIAH
NCGLSKVNRIERGIAYYFNIERDLTEAELATLKDLLHDRMLETVLNHETEAALLFTQQEP
KASTTIDILNGGRQALERANIALGLALADDEMDYLVESFTALKRNPQDVELYMFAQANSE
HCRHKIFNADWIIDGKKQDKSLFKMIKNTFEKTPDFVLSAYKDNAAVMEGSKVGRWFPDP
DGQYRVHQEDVHILMKVETHNHPTAISPFPGAATGSGGEIRDEGATGRGAKPKAGLTGFS
VSNLAIPNFEQPWENPLSKPNRIASALDIMIDAPLGSAVFNNEFGRPALLGYFRTYEEKV
NSFAGKEVRGYHKPIMLAGGIGNIRGEQVQKGEIPVGAKLIVLGGAAMNIGLGGGAASSM
DSGKSKEDLDFASVQRENPEMERRCQEVIDRCWQLGEENPILFIHDVGAGGLSNAMPELV
HDGKRGGKFDLRSILCDEKGMSPLEIWCNESQERYVLAVAPENLELFTSLCERERAPFAV
IGEATQAEHLILHDSHFDNNPIDLPMNVLLGKTPKMMREVLSKTVENQPLKIESIQLKEA
FHRVLRLPVVAEKTFLITIGDRSVTGMVARDQMVGPWQIPVSDVAVTTASLDSYHGEAMA
MGERSPVALLDFSASARLAVAEAITNIAGTLIGEMKRIKLSANWMSAAGHTGEDAGLYEA
VKAVGEELCPALGLTIPVGKDSMSMKTTWIDNGEQKSVTAPLSLVISAFARVEDVRKTLT
PQLRTDKGFSSLLLIDLGEGHNRLGATALAQVYKQLGDKPADVVKVQRLKDFYNAMQTLV
AEDKLLAYHDRSDGGLITTLAEMAFAGHCGVEVDISALGDNDLAVLFNEELGAVIQVADS
QLESVREVLKAHNLLGITHQLGTVTADDRFEISRGSHKLFSEKRSELRSIWAELTYQMQR
LRDNPECAEEEFEAKKNPDDKGLSAFLTYDVNEDITAPFINKGVKPTIAILREQGVNSHY
EMAAAFDRAGFNAIDVHMSDLMIGRRNLAEFNAMVACGGFSYGDVLGAGGGWAKSILFNP
KLHEQFSQFFINPNTLTLGVCNGCQMISNLAEIIPGTENWPHFVRNKSERFEARVSLVKI
NEVDSVWFAGMAGSHMPIAVSHGEGQVKFKSVEQFAGLKAQGIIAAQYIDNNGSPTELYP
ANPNGSAEGITAITNLDGRVAIMMPHPERVFRAVSNSWYPENWTEDGAWMRLFRNARMVF
NT seq
3963 nt
NT seq
+upstream
nt +downstream
nt
atgcaaacgtttgctttgttcgttataatacgtctgtttttttatttttcttttatacgg
aactgcaatatgactgtcaaaacctttcgtggctcgcctgctctttctgaatttcgttta
actcaacttcaacaaaaatgccagcaatatcaattgcctattacgtcagtttgtgcagag
tatttgcattttgttgaacaaaaaacatcgcttgtagaagatgaaatcgttaaattacaa
gcattattgcattatggatcaatgttttctgaactcaagcctgcaggatattgtttaatt
gtgactccacgagtggggacaatttcctcttggtcttcaaaagcgacagacatcgctcac
aattgtggtttgtcgaaggtaaatcgtattgaacgtggtatagcctattacttcaatatt
gagcgtgatttaaccgaagcagaattggctacgctgaaagatttattacacgaccgtatg
ttagaaaccgtgttaaatcacgaaacagaagcagccttgctttttactcaacaagaaccc
aaagcatcaactaccattgatattttaaatggtggccgtcaagcattagaacgggcgaat
attgccttgggtttagcgttggcagatgatgagatggattatttagtggaaagttttact
gccttaaagcgtaatccacaggatgtggagctttatatgtttgcacaagcgaattcggag
cattgtcgccataaaatttttaatgccgattggattattgatggcaaaaaacaggataaa
tcgctgtttaaaatgatcaaaaatacctttgagaaaacgcctgattttgtgctttctgct
tataaagataatgctgcagtaatggaaggttcgaaagtcgggcgttggtttcctgatcca
gatggacaatatcgtgttcatcaagaagatgtgcacattttaatgaaagtagaaacacat
aaccatcccacagcaatttcgccatttcctggtgctgcaacaggctctggcggggagatt
cgtgatgaaggggcaacggggcgtggggcaaaacccaaagcaggtttaacaggtttctcg
gtgtctaacctcgctattccaaattttgaacaaccttgggaaaatccattgtctaaacca
aatcgcattgcttctgccttagatattatgatagatgcgcctttaggtagtgcggtattt
aataatgaatttggtcgcccagcattattaggttatttccgtacttatgaagaaaaagta
aatagttttgcaggaaaagaagtacgcggttatcacaagccgattatgttagcgggagga
atcggtaatattcgtggcgaacaggttcaaaaaggcgaaattccagtcggtgctaaattg
atcgtgttgggtggggcagcaatgaacatcggtttaggtggtggtgctgcttcttcgatg
gacagtggtaaatcaaaagaagatttagattttgcttctgttcaacgtgaaaatccggaa
atggaacgccgctgccaagaagttattgaccgctgttggcaattaggcgaagaaaatcca
atcctgtttattcacgatgtgggtgcgggtggtttatctaatgcaatgcctgaattggta
catgatggcaagcgtggaggaaaattcgatctgcgttctattctttgtgatgaaaaaggt
atgtcgccattggaaatttggtgtaatgaatcgcaagaacgttatgtattagccgttgcg
ccagaaaacctcgaattatttacctcactttgtgagcgtgaacgtgccccttttgcagtg
attggcgaagcaacacaagcagaacatttaatcttgcacgatagtcatttcgataataat
ccaattgatttaccaatgaatgtgttattaggcaaaacgccgaaaatgatgcgtgaggtt
ttgtcaaaaacagtggaaaatcaaccacttaaaatagaaagtattcaattaaaagaagca
ttccaccgtgtattacgtttacccgttgttgcagaaaaaactttcttaattactattggt
gatcgctcggtaacaggaatggtagcccgagatcaaatggtggggccttggcaaatcccc
gtgtctgatgtggctgttactactgcttcactggatagctaccacggcgaagcaatggca
atgggcgaacgctctccagttgccttgctagatttctcggcttcggcacgtttagctgtg
gcggaggccattactaacattgctggcaccctaattggcgagatgaaacgtattaaactt
tctgccaactggatgagtgcagcaggtcacacaggcgaagatgcgggactttatgaagca
gtaaaagctgtgggcgaagaactttgtcctgcgttaggcttaactattcctgtgggtaaa
gactcaatgtcgatgaaaaccacttggatcgataatggcgaacaaaaatcagtgaccgcc
ccactttcgttagtaatttccgcttttgctcgtgtagaagatgtacgtaaaacgcttacg
ccacaacttcgtaccgacaaaggtttctcgagtttattgctaattgatttaggcgaaggg
cataatcgattaggtgcgaccgcacttgctcaagtgtacaaacagttaggagacaagcct
gccgatgtggtaaaggttcaacgcttaaaagatttttacaatgcaatgcaaactttagtg
gcagaagataaattattggcttatcacgaccgttcggacggcggtttaatcacaactctt
gcagaaatggcgtttgctgggcattgtggggtagaagttgatatttcagctttaggcgac
aacgatttagcggtattatttaacgaagaattgggagcggttatccaagttgccgatagc
caattagaaagcgtacgtgaggtgttgaaagctcacaatttgcttggtattacccaccaa
ttaggtacggtaactgctgatgatcgctttgagatcagccgcggcagccataaattattc
agcgaaaaacgctctgaattacgtagtatttgggcagaattaacttaccaaatgcaacgc
ttacgcgataatccagagtgtgctgaggaagagtttgaagctaagaaaaaccctgacgac
aaaggcttatccgcatttttgacttacgatgtgaatgaagatattactgcgccatttatc
aataaaggtgtaaaaccaaccattgcaattttacgtgaacaaggtgtaaatagtcattat
gaaatggcagcagcgtttgatcgtgcaggctttaatgcaattgacgtgcatatgtctgat
ttaatgattggtcgtcgtaatttagcagaattcaatgcaatggttgcttgtggcggtttc
tcttacggcgatgtgcttggtgcagggggcggttgggcaaaatccatcttatttaacccg
aaattacacgagcaattcagccagttttttatcaatccaaacacactaaccttaggcgta
tgtaacggttgtcaaatgatctctaacttggcggaaattatcccaggtacagaaaactgg
ccgcattttgtacgcaacaaatctgaacgctttgaagcgcgtgtgagtttagtgaaaatt
aatgaagtggattcagtttggtttgcaggaatggctggctcacatatgcccattgcggtt
tctcacggggaaggacaagttaagtttaaatcagttgaacagtttgcaggcttaaaagca
caaggcattattgccgcacaatatattgacaacaacggtagccccactgaactatatcct
gccaatccgaatggttctgcggagggcattactgcaattacaaatcttgatgggcgagtt
gctattatgatgccacaccctgaacgtgtgttccgtgctgtgagtaactcttggtaccca
gaaaactggacagaagacggtgcgtggatgagattattcagaaatgcaagaatggtattt
tag
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