Haliaeetus leucocephalus (bald eagle): 104829149 Help Entry 104829149         CDS       T08630                                  Symbol OBSCN Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism hle  Haliaeetus leucocephalus (bald eagle) Pathway hle04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:hle00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     104829149 (OBSCN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hle01001]     104829149 (OBSCN)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hle04131]     104829149 (OBSCN) Enzymes [BR:hle01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      104829149 (OBSCN) Protein kinases [BR:hle01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    104829149 (OBSCN) Membrane trafficking [BR:hle04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     104829149 (OBSCN) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 PK_Tyr_Ser-Thr Izumo-Ig Ig_4 V-set_CD47 Ig_6 fn3 SOS1_NGEF_PH C2-set_2 C1-set RhoGEF FN3_DSCAM-DSCAML_C Zwei_Ig_N PH Adeno_E3_CR1 ABC1 IQ RHG20_PH IQ_SEC7_PH Zn_ribbon_RRN7 Motif Other DBs NCBI-GeneID:  104829149 NCBI-ProteinID:  XP_010561564 LinkDB All DBs Position Unknown AA seq 9580 aa AA seqDB search MDYSSFSGVPRFLTRPKAFMVSVGKDATLSCQIIGNPIPVVSWEKDKLPVQSGGRFKTTE DGDLYRLTIYDLNLEDSGQYICRAKNTIGEAFAAVSIKVGEETTVTESAPYFIQKPSSIK VTLGEDAMFKCKVQGSPPLSVNWEKDGRHLQNQADAGRFQIESAGESNALTIQRARLGDS GTYTCRAENPIGSASASAALVVETQGFSNPGSSSHFDTSCGKTASLLSHLQKRREEIRTK GARNATFGALTRTCSVTEGKHAKLSCYVTGEPKPEIVWKKDNEVILEGRRHVIYEDDQEN FVLKILFCKQVDNGLYTCTASNLAGQTYSSVLVTVKEPSIPFKEKLQDLEVREKESATFQ CEVPVPSTETAWFKEETKLRQSKKYNIEEEGTYRRLTVQNVTTDDDAVYICEMKEGSRTI AELSVQGNIIKKLPRKTAVFINDTAIFCVELDNECQNIRWLKNKEEVKPSDRISITCSGK QHTMIIRECKMEDAGEIVFLADESRTSTQFTVTTPKKPPTQPPVDPLVKNKTETSVTLAW SPPKMDRPIPIDGYVVERKKLTGFTWVRCHESHVPVPEFTVSNLSEEADYQFRVSAVNAY GQSPYLEFPGSMHLEPVLAVKTPLTTVEAVPGGDALFTLDLTTTCSGTWYLNGKVLQESE TYIIKRTQTTHTLIIKNVTKNDDGAEVKFVANNVDTSTKMRVKGAAVRFTNKSRDIEKVS ARLREEAKLQAELSDTEATVKWMKDGKELKSNEKYELQTVGKRHILKIHNTAAEDAGVYE CICEGDKMLYQLSVKAFANFINKEKSGGVIRAIAGKQAEFVSETSEANIMVKWYKDGKEI TASKKFTIEDKGKLHKLVASAVTKEDEGTYTCKIGDDTLIFDLKVSDEAVTFVNKPKTTP EISVSPSENLELVCEVSAASGAVVWKKDQTEVKQDQRTTVISQGTHRKLIIKKVTQQDQG SYTCETKDDRTTFQVKVREREDVFTNKDKVQKEVKAILTQNATLSCEVAQEKTDVKWYKE GKLITSSKKFKVESEGKSRRLVVGQVEKKDAGEYTCEAAGQKLTFKIVVTEEEDAFVNKE KVQKEVKAAVTQNATLSCEVAQEKTDVKWYKEGKLITSSKKFKVESEGKSRRLVVGQVEK KDAGEYTCEAAGQKLTFKIDVTDDVFEHKDKVQKEVKAVLKENATLSCEVAQEKTDVKWY KEGKLITSSKKFKVESEGKSRRLVVGQVEKKDAGEYTCEAAGQKLTFKIDVTEPEVVFTN KDKVQKEVKAILTQNATLSCEVAQEKTDVKWYKEGKLITSSKKFKVESEGKSRRLVVGQV EKKDAGEYTCEAAGQKLTFKIDVTEPKPAFINQEKVQKEVNAVLTESATLSCEVAEDTTE VKWYKDGRLLISSRKFKIETAGKTRRLVIEQLEKKDAGEYICEAAGQKLTFKLEPTEPEA KFEKKVVQKEPLIVQEHESFTLTTSVTPETAVVKWFKDGTEIKASKKYEIKSEEASRTLT VNLAESTDTAVYTCQTKNDKQEFKVQVKEIPVKFAKKLEAVNAEIGGSVSLTCDVSHAKG KVVWRRNGVEIKPSRRFQIHEEGIKRTLTITGIRAEDEGEYSCESRDDKSSITITPKAPR VVKFITTLNSVVSEEGKEAVFKCTVSPSDAVVTWLRNGVKIEASKKYVISQKDTNHSLTI TDLTLEDAAEISANAEGVKSTANLRVREASISFKKKLEPRTVEEKDTVTLEVELTKPAEV KWMRNSIILKPSEKIELKAEGTKHTLVVKDITFADRGFYCCESPDDKTQAKINVEMRQIK LVKGLQPLQVSEKGTVTFEVEVSHEDVEGIWQKDGVRLKPSPNVSIGVLGKKHSLTLSSV TLEDAGLISFKADGIHSSGRLTVTELPVKISKPLVDISVTQKDKVAFECELSRPNVDVKW FKDGKELQQSKKVGIISQGNKRSLIIHKCEYEDQGTYTCEAAEDKTSATLKVHARDIKIV KPLEDVEVNEYESASFVCEISHDEVQTQWYKNDNKMKAADNIRMRQDGRTYSLTYMCVQV EDAAEIKFVAEKAESCAQLTVKELPVKIVKPLRDKIALEKHRGFLECQVSRANAKVRWYK KDVEIHPSDKYEIVSDGVYRKLIINDADYEDEDTYTCDAFDDKSSANFFVEEQSISIVKE LCDEDVTEPEEAKFECEISIPSVKPPKWSLRGEVLQAGRNIIMQQEDTIHRLIILKTSAD MTGTVQFSIGKSKSTANLLVRDYHIQITRKMEDKTALERHSVILSCDFRPSPKVVKWFKD HTPIEPSEKYKIKREQHSAELKILKVKPEDAGVYKCRAGNAETEATLTVEARNVEVLKHL QDVEIEEESSAVFSCELSHDDEDVEWFLNGTLLYTNNFNDIRNVGNCYTLTMKHVKPEDA GTVTMKSDKVSESVRLKVIEKPAVFMKSLDDVFGEERGMIKLECEVSKEKVKPVWKKDGV KLTSSNKYEQIQSGKTLCLLIHDLEKTDAGLYTCDIGTDVAKSKVSVQELNIGITKRLKN TEIQEGEDCTFECILSHESIDDFNWTLNGSKVKSGGRFKASNTGRKYTLNIKSVIPDDSG EVVFTARGLISKASLVVKEKPTEITKQLEDKTSTAGQDISVSCELSKPDVSIRWYKDGKA IRKSQKYDLHQEGTQAILIIHDSTVKDSGEYTCETEVSKTKARITVQEKPNYFVKELSDL KADESGTAVFMCQSEKAASSVVWRKGIAELRTSRKYEITQKGQILQLTIKNLEKNDSDTY TCDIGDAQSRAKLVVQGQKVLITEDLEDVTVLEGESAVFKCRISPVDYSKVQWFLDKTPL HTNELNEIESQPGGYHLLMLKKLSLKDSGVITFEAGDKKTSASLVVKEKPCIFTKELLDT EVTEGEDVILHCETSKSDSPVKWCKDGKSLRNSSKYNISRLGFEAKLVIHRAEERDSGRY ECEAGAAKSSAVITVKELPVLFKQELQNEEAKEGKQIKLTCELSKPDTPVKWMKGDTVLY ASEKYEFKQHGTVAELIIRDVKSIDSGDYTCSTGEQKTTARVKVNAVPVLFKQALENTEM EEGKSVSLRCELTKADATVVWKKGEATLQASAKYEMKQKGTVAELVIHHAEPEDAGRYTC DTGDQQSTAHVKIHAASALIQELKSVEAVEGGTATLRCQLSREVPVEWRKGHALLRPSNK YRMRQEGTLAELLIHDLDPRDAGDYTCVVGNEKTTAALSVNALPILFQEEMSKKEATEGE AVTLHCKLSKSAPVEWRKGSKVLKPSEKYKIEQEGPFAELMIRDLELADAGDYSCVCGDQ ETTAALTVNVLPALFTKELTDEEATEGKSVSLRCELNKAAANVEWKKGFKTLKSSDKYKM KRKGVVAELIIQNLDVTDAGNYSCVCGDQQTMAVLTVHALPAFFKEGLKNREATDGATAT LHCELSKVGVPVEWKKGDKTLKPSDKYRMRQEDTAAELLIRDLVVEDTGEYTCVCGDQKT SAVLTVHALPALFKKDLVNMEATENGTAVLQCELTKPTPVEWRKGQKVLKPSEKYKMRLK DTIAELTIHSLEERDAGDYTCVCGDKMTTASLTVHALPPHFKKELKNVEATENGMATFCC ELNKPAAAVEWRKGDRALETNDKFTMRCEGTTAELVIRDLDLTDAGDYTCCYEDQKTTAA LKVNALPAHFKKEMKNEEATEGGTATLQCELSRAASVEWKKKHKVLKLSEKYTIRQEGTT AQLLIHALEVKDAGEYTCVCGDEKTTAALTVHALPALFKEELRNEEATEGEVVTLRCELT KTASVEWKKGHTVLKPSEKYKMRQKDVTAELVIHNLNENDAGDYTCVCGDKQSTASLAVH ALPARIKESLKDEEVTEGQAATLRCELSKVAQVEWRKGSRLVKASDKYKMRQEGTVMKLL IHDVELKDAGEYTCVCGEQETTAALIVHALPALFKEELKDLQATESQTATLRCELTKAAA VSWQKGNKILRASEKYIMRQDNTLAELEICDLELKDAGDYTCVCGDQHTTASLTVNALPV VFKEELKNEEVLEGTSVSLHCELSKAAPVQWKIGSKVLKASDKYQMRQPGTTAELVIRDL EVKDAGDYTCVCGDQKTTATLTVHALPPLFKEELKNKEAEEGGEVALRCELTKAAPVEWR KDQRILKESEKYKMRQEGTKAELVIHKIAEEDAGDYTCVCGEHQTTAVLTVQAVPPFFQE EMTSEEAVEGGTATLRCELSKASARVQWKKGPRVLTSDKKYSTRREGCVVELVVHDLDLN DAGEYTCVCGDKTTTAVLTVHALPPEFKKDLKDLEAVESGTAALHCELTKPAVVKWMKGQ EVLKASSKYKMSQDGAVAKLIIHELDMEDTGDYTCVCGDQRTTATLTVNALPALFKQELQ NTEAEEGGTATLRCELTKPKAPVEWRKGDITLYPGLKYEMKQQGSTAELVIYDLELDDSG RYTCDSGHQQTTAVVTVHALPVTFKQPLQNKESEEGGTATFCCELSKPNAAVEWRKGGVG LQPSQKYEMRQRECLVELLIHNLKLEDTGEYSCDTGDQETKASLNVKALPVLFKKELKDK EAEEGAAVKFQCELTKDNATVEWRKGTMQLFACAKYEIKLSGRTAELVIHNIEPEDASDY TCDTGDQQSTAVLRVNAIKPQLKQQLKNEEVEVGGTARLRCEISISKAEVEWRKDGVVLH SSSKYEMWQDGTLRELRVHRLEPRDAGEYSCKAGDETSSAKLTVKEPDVTIVSGLKDMVV FEGDDVTFRCQVSHENARDVEWKLQDVVLQNNEMNEISVEKGKIHTLTLRKVTEQDIGTI TFRVGPHTSTAELTVKEPAAAIVETLKDVTLYEGEDAVFECRLSRETTQDAQWFLGDVPL QSNEMNEIRVQGTRHTLILRKVTLEDCGPISFKVGQHTSAAQLTVQAKNSILQGLENVEA VEGGEALFECYLSKPECYNYNWLIDDEPAKTTENTEMVYFENGRRHLLLLKNLTPQDSCR VTFTCSDAMTSAFLTVKGWRLQILQPLTDVEVSPGEKATFSCVLSEAVPINEVAWYSNDI EIQSDEDWEVQADGNKYKLILKKAQPHHSGEVTFASREAIASAKLSVIAHPDPPEEPEVL SKNSHSVTLSWYKPLSDGGCDILGYNVERKIPGIGWQSCSKAIIQNTEFVVDDLTLGEPY RFRVSAINKVGASEPVHFPQTVRLEPPVTVTHPLVGGSVSEGEVARLECQLSSETEKRVT WLKGKEQIQAGGRYEILSNGKKQILIIHAFKPEDQDTYTCMVSPEVKSVASLCLEVPTVA MLKEIVQEASSASQPEELVDGHVQPSLPPEAAQEGDLHLLWEALAKKRRMSREPTLDSIS EVPEEDEKLQKLRKEEAEMSHYYSEEYSTCDELARTGEADFSFTSSDDESRAGTPSLVNY LKKAGKASVSVTSKVQSIPTGKLWKQWEKSSVETVVAAPAAKPAEPEVPDLDDPSMNKAA VKIQAAFKGYKVRKEIKQQECPVFTETFKDFSGEPGSTLHLECVAHSKTDMKVRWLKDGE ELSDGRYYHIDNYSDGTCSLIITGLERKDAGKYTCEASNKFGKVSHSAKVVIGSTDSETE SSSGSELDDAFRKAGRRLHRLFKAKISTEISDVEEELFVSADEGDIEVVDHQTYREDDQY IYIKFEILSEAKTAATRFREMFGALGIPVEIDILEQGPKKIELRIGKATPPTHGKFAPPV VRPPPPLLTTDTAPMFMTELQNQEVQDGYPVSFDCIVVGKPLPTVRWFKDGKAIEENDHY MINEDQEGCHQLIITAVVPTDMGVYRCLAENNMGVASTKAELRVDLTSTDYETAADATET SSYYSAKEYISSREQEESTTEEEQLPQIFDELHDIHVAPGASLAKFHLKVKGYPQPRLYW FKNGQPLKASDRILKTDKQEFHSLEIRDVTKADAGQYSIFVINSAGSAFSSARLLVKDPD EKEEPSETDSFEQLIPPRFLERFTNKKVKKGASITLSVKVEGHPPPTITWLKEESQEDIL WIKPDTPGYKLASSNMHHSLILLDVKKKYSGTYTCIATNKAGQSICTATLEVADVKEAEV LTQERVMVSEAIMTTLGAIHPSETGEGDLETGREGVPKSPISLADVGSEEFFQKLTSHIS EMVSAKISQATLRVPGAESDDESKTPSASPRHGRSRPSSIAQESSSESEDGDSRGEIFDV YMVTADYVPAAPDRETITLKEGQYVEVLDSAHPLKWLVRTKPTKSSPSRQGWVSPAYLDK KLKLSPEWGTTEAPEFPGEFVSEDEYKRKLSVLIQELLISEEDYIQDLQFLQTHHLKFTE TCPNVPGAVASQKSTIFRNIDDIARFHSSVFLQGLQKCDTDDDVAMCFIKHEAEFNKYIQ YLVGRVQAESIVVSKAVQDFYKRYTDEILTNEDPSQPLIPPLQHYLEKPINRIQQYQTII KELIRNKARNSQNCTLLEQAYAVVSALTRRAENNLHVSLIENYPGTLESLGEPIRQGHFI VWEGAPGARVAWKGHKRHVFLFKNYIVICKPKRDTKTDTYSYIFKNIMKLNNIDVNDLVE GDDRAFEIWHEREDLVRKYLLQARTVNIKNSWVKEICGIQQRISEPVWIPPDFEEELAEC TAELGETVKLACKVTGAPKPSVSWYKDGKPVEVDPHHIIIEDPDGSCTLILDNLTGVDSG QYMCFASSPAGNASTLGKILVQVPPRFVNKVRNAYFVEGEDAQFTCTIEGAPRPQIRWYK DGVLLKNTSKYQTFSEPRSGIIVLVVKNPSNEDMGHYECELVNRLGSAKSGAELYHHSAA ALTQERRGDQAITIEGHSPSRSPRAEPTPEPVYVSKIRQPVHRHEQETTSKSAVPMLFVT EPEDRQGAAARDVITETKGEEKKPKWVEVEEIIEFKVKKSPKPARKRGSSPAKQGKDDSG VLTFTFPSSRPRRSPEDDPNTNNSNNKLVEQSKSLPNDSLSEADIQPLVYATEEEGPQVS SEDRSSPCESDQLGNSSFMDYGTEGKSFPQETSARYGSDVASPLLACGGEPLVFSFETAA ADQQELLFSPASPEVKEEVDELDISWPIEEGVPEVMQDVLPEEDNVIIVDEPEELQTDDI STRDRKILTHNGKVLTLEDLEDYVPKEGETYGCDDQNRRAEKPCEISVLQTEINEPTIGK PVLLNLVRPVVSKPRQRFFSQFEEHIPGGMFMTASRVTGVQSVGPSNISFHVTPGVHAAT AAASPGPSFTVKPSFCTEVQLSADNGQSSFKTEVSTRTLSYGTVGMTSPQSEVETSVQAS LQRADKEIKTALKKLVDSASLLVTLPPGMREEVGGLGLPGSIPSDHSETAAGPSVLVHEA STQTQTAGGHDKAQRQVPAEEPSVPKPSPGPSSEETAAGDESTQERTVPITRTSPATGAG GWYRREGDVVWDVHSEVYIETTERTCVYKTEEKTPTSPPYMQVTIEDVQVNSGERAKFQA VIEGTPQPTVLWFKGTSLLTDSNRLHQGKEGTTYFLVVDNAVSEDGGVYTCVAKNAGGEV LCKAELIVHEGNKDQAAKKVATRRKLHSLYEVKQEIGRGCFSFVKRVVHKGNRVSCAAKF IPLRSKTKARAHQERDILASLSHDRITRLLDQFETRKTLILILELCSSEELLDRLFKKSV VTEAEVKLYIKQILEGIKYLHDNNILHLDIKPLNILMVYPEREDLKLCDFGFAQKITPSE PQFSKYGSPEFVAPEIVSQSPVSKGTDIWAVGVITYLSLTCKSPFAGENDRGTLINIQNG EISWTTPDFVHLSEDAKDFMKGILQQDPKARPSASDCLSHQWFMHNPPLEAAHFINTKQL KFIVARSKWQRSLMCYKSILVMRSIPEILERTHDNTSLAISRHLIDESTSSSTSGSSSDN ENSHFPTKRHFGSTPELHLSIFDAPSHQEPPKHAREEKQTKISVPPVKPMRRKYASMKGE VGDKSPTESKELMASILKEKEEGLLPRLQDEGAEQSQRSGAAEPSSVRTSTESTSNLCQK EKPDVFLSDKDRIEKAGDGTEKPPVCVPRQSVIKSTFYSQAAELPARGPSSPGREFRRHL DRARRTFRKAGYSKVPLSGLREPLLEQFELEEEEGKSDYGDDHRESLLGSLTKSASFDTA RKPPHPAIAGGSRSRSLDDYRLRASRSVREQHILEEDCDILSQESCAEGGDHCDISAGPG KGCFVDTAKQEDFRRTSKDCSEEQPPPSTQCEGNGCPAGFVQQLERLPVSPHRSENRKHL LKKSKATYIEEEVKDLEGKSPILTAQGSDVTASSAQKHESMEGKSFPGSASDTAFQEGKQ SISTLTKPETTSKTAPTSKGDAYLPQESAHSTDVHPDLKGGSLLIQRTAPVPPWKDKRQK HSHEKTSAHSVVKSDLTEHESSAVLTGPQTETDSLPVCKDKSQELSGQTVPATTALVGIR PDTLTALHTADEGAHQKMKTHKEMKSAVLEDEGPGITGITPPSAHDGESQACKRAAGHVD TESAVLKGEHLIPKVPPPKSTPTLVSDGAEKAEREWPARSKDRLAVLRNESSAVTEVVPS LAHEAEIEGTEPQKVSEGRGTVPAVRESRHRARTVSSQNTGLPSACEKEKQERSKAPLRS EVRSVVTASASRAAGQTMPAPVPKAGPQVFEQHRVVHPGGRVSTDLKSGPPGVLTASPPE AAPASVYELEYEEYPKVYGEGRSVALESGSWDAGKTVPPSLGKDQSQELSHHRSSFYSDE ESAVLEGLVDEMVSLSEEMNVWAESVSGEEECRKPISAPTEMFYKGLGTQAPMDTSFPSV QGGKREVSELDDLAEPYLVVSEESVVLEGQGVQTVPHECEHLEDLAFESPTSSQVSVSST ESLDTGKRPSQVTVSKDTGKHPEVSLVKIKDLSDETPSLGSGTPKLDISEVEPAYLNFSD LYDIVYFPFEFMNYRKPPPKPTGRRFIPFGERARSPPARHLHKDKRLCIREEAEDKNRKN HLEISEDSKATNLLAMGKGSESHKEMYGPQKGSSGKQKSSFYNKPGLFKPYARSHSVEQS VEQSLKKKVKASVAHISKILKGKISPEPEAEEGSLKRKSALSSFKFSSLMPKEKAPSFTE ELIDQAAAIGQCVTLSCRTAAHSSLHINWFRDGIAVHSSSRILISATLKNFQLLTILSVN ADDFGIYTCVATNSLGSASTSCVIRKAELPPSPPPPDIVEVYEDGVQVVWKPVETNTPVH YTVQCKSEDGEWTTLASDIADCCYYAKNLSKGFIYCFRIACTSKAGMGPYSDPSAKVKIT GKDQMAATEEESEIITPSEPFPTYQTYAFQTEIKRGRFSIVRQCREKVSGKTLAAKIIPY WQEDKQTVLLEYQVLRKLHHTNIAQLKGAYVSPRHLVLIQEMCVGPELLHSLALRTSYSE VEVRDYLWQILSATEYLHAHNILHLDLRSENMIITEPNLLKLLDFGNAQFYTQDKVITMD KCMDYVETMELLTEQGALPQTDIWSVGITAFIMLSANYPISSDVACEFLRTTRRGKVKLT RCYAGLSGGAVSFLQSTLCANPWDPPHQHGSPTDLLTFVCSRGRPSASECLQSPWLQETG LDNRQQALVTFPTTKLRNFLTEREKKRGLLCSKYGLMIAQ NT seq 28743 nt NT seq  +upstreamnt  +downstreamnt atggattacagctcgttcagtggagtcccccggttcttgacccgacctaaggcgtttatg gtgtctgtggggaaggatgccaccttgagctgccagatcattggaaaccccatcccagtt gtgagctgggaaaaggataaacttccagtccagtctggaggaaggtttaaaaccacggaa gatggggatctctatcggctaacaatctatgatctgaacctggaggacagcggccaatac atctgccgggccaagaacaccattggggaagcttttgcagctgtcagcatcaaagttgga gaggagaccacagtaacggagtcagccccgtacttcatccagaaaccctcctccatcaaa gtaacattgggagaagatgccatgttcaaatgcaaagtccagggcagccctcccctctcg gtcaactgggagaaggatgggagacacctgcagaaccaggctgatgctggacgcttccag attgagtctgctggggagtcaaacgctctcaccatccagcgagcccggcttggggacagc ggcacctacacctgccgggcagagaatcccatcggctccgccagcgcttcggctgcgctg gtggtggaaacgcagggtttttccaacccgggcagcagcagccacttcgataccagctgc ggcaagacggcatccttgttgtcgcacttgcaaaagaggcgggaggagatcaggaccaaa ggggcccgcaacgcgacttttggggcgctgacacgcacgtgcagcgtgacggaggggaag cacgccaagctgagctgctacgtgacgggcgagcccaagcccgagattgtgtggaagaag gacaacgaggtcattttggaagggcggcggcacgtcatctacgaggacgatcaggagaac tttgtgctgaagatcctcttctgcaagcaggtagacaacgggctgtacacctgcacggct tccaacctggcaggccagacgtacagctccgtgctcgtcaccgtcaaagaaccctcaata cccttcaaggaaaaactgcaggatcttgaagtgagggagaaggaatctgccaccttccaa tgcgaagtgcctgttccaagtacagagacagcttggttcaaggaggaaaccaaactccgg cagagcaagaaatacaacatcgaagaagagggcacgtatcgccggctcactgtccagaac gtcaccacagacgatgatgctgtctatatctgtgagatgaaagaagggagcaggaccatc gcagagttgtctgtccaagggaacatcattaaaaaacttccacgaaagactgcagtcttc ataaatgatacagccatattctgtgtggagctggacaatgaatgccagaacatccgatgg ctgaaaaataaagaagaagtgaagcccagtgatcgaatctccatcacgtgctccggcaag caacataccatgatcatccgagagtgtaagatggaagatgctggtgagattgtcttcctg gctgatgaaagcaggacttctacccagttcactgtgaccactcccaaaaaacctcccacc caacccccagttgaccctctggtgaaaaataaaacagaaacctcagtgacgctagcatgg tcccctccaaagatggaccgccccattccaattgatggctacgttgtggaacgcaagaaa ctaactggctttacctgggtgaggtgccatgagtcccacgtccctgtcccagagttcaca gtgagcaacctgtcggaagaggccgactatcagttcagagtttctgcagtcaacgcctat ggacagagcccctacctggagttcccggggagcatgcaccttgaaccggtcctggctgtg aaaacccccctgacaaccgttgaagctgtacctggaggggatgccctgtttactcttgac cttacgacgacatgttccggcacttggtaccttaatggtaaagtcttacaggaaagtgag acctacatcattaagagaacccaaactactcacaccctgatcataaagaacgtcaccaag aacgatgatggagcagaagtgaaatttgttgccaataatgttgacaccagcaccaagatg agagtgaaaggtgctgcagtgagatttaccaacaagagcagagatatagaaaaagtctct gctcggctgcgggaggaagccaaacttcaggctgagctttcggacacagaggctactgtg aagtggatgaaggatgggaaagagctcaagtccaatgaaaaatatgaacttcaaactgtg gggaagaggcacatcctgaaaattcacaacactgcagcagaggatgctggagtttatgag tgcatctgtgaaggggataaaatgctctatcagctttcagtgaaagcatttgcaaacttc ataaacaaagagaaaagtggaggagttatcagggccattgctggaaaacaggctgaattt gtttctgagacctcggaggccaacatcatggttaagtggtacaaagatggcaaagaaatc acagccagcaagaaatttaccatagaagataaaggaaaactgcataagcttgtggcttca gctgtgacaaaagaagatgaaggaacatacacatgcaaaattggagatgacactcttata tttgatttaaaagtctcagatgaagctgttacttttgtcaacaagcccaaaacaactcca gaaatttcagtcagtccttctgaaaaccttgagctggtgtgtgaggtgtcagctgcgagc ggagccgtggtatggaagaaggatcaaactgaggtgaagcaagaccagaggacaacagtc atctcccaggggacacaccgcaagctcatcatcaagaaggtgacacagcaagaccaaggg agctatacctgtgaaactaaagacgacagaacaacattccaagtcaaagtcagagagaga gaagacgtgtttacaaacaaggacaaagtacaaaaggaggtgaaggctatactgacacaa aacgccacgctgagctgcgaggtggcccaggagaagaccgacgtgaaatggtacaaggag gggaaactgatcacctcgagcaagaagttcaaggtggagtcggagggcaaatcgcgtcgt ctggtggtgggtcaggtggagaagaaagatgctggggagtacacctgtgaggctgctggc cagaaactgaccttcaagattgtcgtcacagaggaagaagatgcatttgtcaacaaagag aaggtgcagaaagaggtgaaagctgcagtaacacaaaacgccacgctgagctgcgaggtg gcccaggagaagaccgacgtgaaatggtacaaggaggggaaactgatcacctcgagcaag aagttcaaggtggagtcggagggcaaatcgcgtcgtctggtggtgggtcaggtggagaag aaagatgctggggagtacacctgcgaggctgctggccagaaactgaccttcaagatcgat gtcacagatgatgtatttgaacacaaagacaaggtacaaaaggaggtgaaggcagtgctg aaggagaacgccacgctgagctgcgaggtggcccaggagaagaccgacgtgaaatggtac aaggaggggaaactgatcacctcgagcaagaagttcaaggtggagtcggagggcaaatcg cgtcgtctggtggtgggtcaggtggagaagaaagatgctggggagtacacctgcgaggct gctggccagaaactgaccttcaagattgatgtcacagagccagaagttgtgtttacaaac aaagacaaggtacaaaaggaggtgaaggctatactgacacaaaacgccacactgagctgc gaggtggcccaggagaagaccgatgtgaaatggtacaaggaggggaaactgatcacctcg agcaagaagttcaaggtggagtcggagggcaaatcgcgtcgtctggtggtgggtcaggtg gagaagaaagatgctggggagtacacctgcgaggctgctggccagaaactgaccttcaag atcgatgtcacagagccaaaacctgcatttataaaccaggaaaaggtccagaaggaggtg aatgctgtcctgacagaaagtgccaccctcagctgtgaggtagcagaggatacaactgaa gtgaaatggtataaggatggaagactgcttatttcctctagaaaattcaaaatagaaact gcgggcaaaacccggcgcctggttatagagcagctggagaagaaagatgctggagaatat atctgtgaggctgcaggccagaagctgactttcaagttggaaccaactgaaccagaggct aaatttgaaaagaaagttgtccagaaagagcctctcattgttcaagaacatgaaagcttc acactgactacttcagtaacacctgaaactgctgtagtaaagtggttcaaggatggaaca gaaatcaaggcgagcaagaaatacgagatcaagagtgaggaggcatccaggacgctgaca gtgaacctggctgagagcacagacactgctgtgtacacgtgccagacaaagaacgacaag caggaattcaaagtacaggtgaaagaaatcccagtgaagtttgccaaaaaacttgaagct gttaatgccgagattggaggcagcgtctctttgacctgtgatgtgagccacgccaaaggg aaggtggtgtggcgcaggaatggcgttgagatcaagcccagcagacgtttccagattcat gaggagggcatcaaacgaaccctgacaataacagggatccgggctgaggatgagggagag tactcctgcgagtccagagatgacaagagcagcattaccatcacccccaaagctcccaga gtggtgaaattcattacgactctcaacagcgtggtctctgaggaaggaaaagaggctgtg ttcaagtgcaccgtctctcccagtgatgccgtggtcacttggctcaggaatggtgtcaag attgaagccagcaagaagtacgtgatctcgcagaaggacaccaaccacagcctcaccatc actgatctgaccctggaagatgcagctgaaatctccgccaatgctgagggtgtcaaaagc acagccaacctcagagtccgagaggcctcaatctcattcaagaagaaactggagcccaga acagttgaagagaaggacacagtgaccttggaggtagagctgaccaagcctgcagaggtg aagtggatgaggaacagcatcatattgaagcccagtgaaaaaatagagctcaaagctgag ggaacaaagcataccttggtggttaaagacatcacctttgcagacaggggcttctactgc tgtgagagtcctgatgacaagacccaagccaagatcaatgtggaaatgaggcagatcaag ctggtgaaaggtcttcagcctctccaagtctccgagaaagggaccgtcaccttcgaggtg gaggtatcgcatgaggacgtggaagggatctggcagaaggatggcgttcggctgaagcct tcaccgaatgtcagtattggtgtcctggggaagaaacattcgctgactctctcttcggtg actcttgaagatgcaggactcatctccttcaaagcagatggcattcattcatcagggagg ctcactgtgacagaactgcctgtgaaaatcagcaaacctttggtagacatcagtgtaact cagaaggacaaggtcgcattcgagtgtgagctgtccaggcccaacgtggatgttaagtgg ttcaaggatgggaaggagctccagcaaagtaaaaaagtggggattatttcccagggaaat aagagaagcctcattattcacaagtgtgaatatgaagaccagggaacctatacatgtgaa gcagctgaagacaagacatcagctaccctaaaggttcatgcccgagatatcaagattgtt aaaccactggaagatgtggaagtgaatgaatatgagagtgcatctttcgtctgtgagatt tcacacgatgaggtccaaacccaatggtacaaaaatgacaacaagatgaaggctgccgac aatattagaatgcgtcaagacggaaggacctattcactgacttacatgtgcgtccaagtc gaagacgcagcagagatcaaatttgttgcagaaaaagcagaatcttgtgcccagcttact gtaaaagagctgcctgtaaaaattgtgaaacctttacgagataagattgctcttgaaaaa catcggggtttcctggagtgccaggtgtctcgtgccaatgccaaagtgaggtggtacaaa aaggacgttgaaattcaccccagtgacaaatacgaaattgtgagcgatggtgtctatcgg aaactcatcatcaatgatgcagattatgaagatgaagacacgtacacttgtgacgccttt gatgacaaaagcagtgctaatttctttgttgaagagcaatccattagtattgtaaaggag ttgtgtgatgaggatgtgactgagcctgaagaagccaagtttgaatgcgagatatccatt ccatccgtgaaaccccccaaatggtctctacgtggagaagtcttacaggctggcagaaac attataatgcagcaagaagacaccatccacaggctgataatactgaaaaccagtgctgat atgacaggcaccgttcagttctccattggcaaatcaaaatccacagcaaacttgcttgtc agagattaccacatacagatcaccaggaagatggaggacaagacagctctggagcgccat tcagtcatcctgtcctgcgacttcaggccttctccaaaggttgtgaagtggttcaaggac cacacacccattgagccctccgagaagtacaaaatcaagcgggagcagcattcggcagag ctgaagatattgaaggtgaagcccgaagacgctggtgtgtacaagtgcagggctggaaac gcggagaccgaagccacgttgaccgttgaagcccgcaacgtagaagtactcaaacacctg caggacgtggaaattgaagaagagagttccgccgtcttctcctgcgagctgtctcatgac gacgaggatgtggaatggttcctcaacggcaccctcctttacaccaacaatttcaatgac atcaggaacgttggcaattgctacacgctgacgatgaagcacgtcaagcctgaggacgct ggcacagtgaccatgaagtcagacaaggtgtcagagagcgtgcgtctgaaggtgatagag aagcctgctgtcttcatgaagtccttggatgatgtttttggtgaggagcgaggcatgatt aaactggaatgcgaagtctccaaagagaaggtcaaacctgtttggaaaaaggatggtgtg aaactcacttctagtaacaagtatgagcagatacagtctgggaagaccctgtgcctcctt atccatgaccttgaaaagacagatgcaggtttatacacctgtgatattggcactgacgtt gccaagtcaaaggtcagcgttcaggaactgaacattggcatcaccaaacggctgaagaac actgaaatccaggagggagaagattgcacttttgagtgtattttgtcccatgaaagcatt gatgacttcaactggacgctgaatgggagcaaagtgaaaagtggtgggcgatttaaagcc tctaacacgggtcggaaatatacgctcaatatcaaaagtgtgattcctgatgattctgga gaagtcgttttcactgcccgtggtctaatctccaaggcttctctagttgtaaaagaaaaa cctactgagattacaaaacagctggaggataaaacatccacagcggggcaggacatcagc gtgagctgcgaattgtcgaaacctgatgtgagcatcaggtggtacaaggatggcaaagca atccgaaaaagccagaaatatgacttgcaccaagagggaacacaggccattctgatcatc catgactccacagtcaaggacagtggggagtacacctgtgagacagaggtctctaaaaca aaagccaggatcacggtgcaagaaaaacccaattattttgtcaaggaactttcagatctg aaagctgatgaaagtggaactgcagtttttatgtgccagagtgagaaagctgcatcctct gtagtctggaggaaaggcatagctgaactcaggaccagcaggaaatacgagatcacacag aaaggacaaatcctccagctgaccataaagaacttggagaaaaatgacagtgatacttac acctgcgacattggtgatgcccagtccagagccaagctagtcgtgcaaggccagaaagtg ctaataacagaagacctggaagatgtcactgtgttagagggagaatctgccgtgtttaaa tgcagaatctctcctgtagactatagcaaagtgcagtggtttttggataaaaccccactc cataccaatgaacttaatgagatcgagtctcagcctggtggatatcacctgctaatgctg aaaaaactctcactgaaggactcgggggtcattacatttgaagctggtgataagaaaaca tctgccagtttggttgttaaagagaagccctgcatcttcacaaaggagctccttgatact gaagtcactgagggagaggatgtgatccttcactgtgaaacctccaaatcagacagccct gtaaagtggtgcaaagatgggaagagccttaggaattcttccaagtataacatcagccgg ttgggatttgaagccaagcttgtcattcacagggcagaagaaagagacagtggcagatat gagtgtgaggctggagcagctaaaagtagtgcggttattactgtcaaggaattaccagtt cttttcaagcaagagctccaaaatgaagaagctaaagaaggaaaacaaatcaagctgacc tgtgagctcagcaaacctgatacaccagtgaaatggatgaaaggagacactgttctctat gccagcgagaagtatgaatttaagcagcatggtactgtggcagagctcattattcgagat gtcaaatcgatagactctggggactatacctgcagcactggggaacagaagaccactgct cgggtgaaagtaaatgctgtccctgtcctttttaaacaagccctggagaacacagaaatg gaagaggggaaatctgtctccttgcgctgcgaactcacaaaagctgatgccaccgtggtg tggaagaagggagaagccacgctccaggcaagtgccaaatacgaaatgaagcagaagggg acagtggcggagctggtgattcatcatgcagagccagaagatgcgggaagatacacctgt gacactggagaccagcagagcacagcccacgtcaaaatccatgccgcctctgcgctcatc caagagctgaagagcgtggaagctgtggaaggtgggactgccaccctgcgatgccagctg agcagagaggtccccgtggagtggaggaaggggcacgctcttctccggccgagtaacaag tacaggatgaggcaggagggaacattggctgagctgctgatccatgatctggacccaagg gatgctggagactatacatgtgtagtggggaacgaaaaaaccacagcagccttatcagtg aatgccttgcctatcctcttccaagaagaaatgtcaaaaaaggaagctacagagggggag gcagtcactttgcactgtaaactgagcaaatcggccccggtcgaatggagaaaggggagt aaggtcctcaagccaagtgaaaagtacaaaatagagcaggaaggtccctttgcagagctg atgatccgggatttggaattggcagacgctggtgattacagctgtgtgtgtggagatcaa gagactacggctgctttgacagtaaatgtcctgcctgctcttttcaccaaagaactgaca gatgaagaagccacagaaggtaaaagtgtgtctctgcgctgtgagctgaacaaggctgct gctaacgtggagtggaagaagggattcaagacgctcaaatcaagcgacaaatacaaaatg aaacgcaaaggcgtcgttgctgagcttataatccaaaatctagacgtgacggatgctggg aattattcctgtgtgtgtggagaccagcagactatggcagttttaacagtacatgctttg cctgcatttttcaaagaaggattgaagaacagagaagccacggatggtgcaacagccact ctgcactgcgagctgagcaaggtcggtgtcccagtagagtggaaaaaaggggacaagaca ctcaaaccaagtgataagtataggatgagacaagaagacaccgctgcagagctgttgatc cgagatctggtggtagaagatacaggagaatatacctgtgtgtgtggagatcagaagacc tcggctgtcttgacagtccatgctttgcctgcactgttcaaaaaagaccttgtcaatatg gaagccacagaaaacgggacggctgttctgcagtgtgagctaactaaacccactccggtg gagtggaggaaagggcaaaaggtgctcaagcctagcgagaagtacaaaatgagactgaag gataccattgctgagctgaccatccatagcctggaggaacgagatgcgggagattacaca tgcgtgtgcggagacaagatgactactgcatccctgacagtgcatgcccttcctccgcat tttaaaaaagagttgaagaacgtggaagccacagaaaatggcatggccactttttgctgt gaactgaacaagccggcagctgctgtggaatggaggaaaggagacagggccctcgagaca aatgacaagttcaccatgagatgtgagggcacaactgctgagctggtgatccgtgattta gatctgacagatgctggagattacacatgctgttatgaagatcagaaaactaccgctgcg ctaaaagtgaacgccttgcctgcacacttcaagaaagagatgaagaatgaagaagccact gaaggtggaacagccacgctacaatgtgagctatctagggctgcctctgtggagtggaaa aagaaacacaaagtgctcaaattgagtgaaaaatatactataagacaggaaggtactaca gcgcaactgctgatccatgctttagaagtcaaggatgctggggagtatacctgtgtgtgt ggagacgagaagactactgcagcactgacagtgcatgcccttcctgctctcttcaaagaa gagttaagaaatgaggaagccacagagggtgaagtggtgactctgcgctgtgagctgacc aagaccgcttcagtggagtggaaaaagggacacacagtactcaaacctagcgagaaatac aaaatgaggcagaaggatgtcactgcagaactggtgatccataatctaaatgagaacgat gctggtgattatacctgtgtgtgcggggataagcagtccacagcttccttagcagtacat gcgctgcctgcacgcatcaaggaaagcctgaaagacgaggaggtaacagaaggtcaagca gccactctgcgctgtgagctgagcaaggttgctcaagtagagtggagaaagggaagccgt ttggtcaaagccagcgacaaatacaaaatgagacaggagggcacggtcatgaagctgctg atccatgacgtagaattgaaagatgctggagagtacacttgtgtgtgtggagaacaggag acgacagctgccttgatagtgcatgccttgcctgcacttttcaaagaagaactgaaggac ctgcaagccacggaaagccaaacagccactctgcgctgtgagctgaccaaggctgcagct gtgtcatggcagaaaggaaacaaaatactcagggcaagtgaaaagtacatcatgcggcag gataatacccttgctgagctggaaatttgtgatctagagctgaaggacgcaggagattac acctgtgtgtgtggagaccaacacaccacggcttctctgacagtgaatgccctgccagtg gttttcaaggaagaactgaagaatgaagaagtcctagaaggaacatcagtctctctgcat tgtgaattaagcaaagcagctccagtacagtggaaaatagggtccaaagtgctcaaagca agtgacaaatatcaaatgagacagcctggcaccactgcagagctagtcattcgtgaccta gaagtaaaggacgctggagattacacctgtgtgtgtggtgaccagaagacaacagcaacc ttaacggttcatgctctgccaccactctttaaggaagagctaaagaacaaggaagcagaa gaaggtggagaagtcgccctgcgctgtgagctcaccaaggctgctccggtggagtggcgg aaggatcagaggattctcaaagagagtgagaaatacaaaatgaggcaggaagggaccaag gcagagctggtgattcataaaatagctgaggaagatgcaggagactacacctgtgtgtgt ggagagcaccagactacagctgtcttaacagtacaggctgtgcctccatttttccaagaa gaaatgaccagcgaggaagcggtggaaggtggaacggccactttgcgctgtgagctcagc aaggcatctgcccgcgttcagtggaagaagggccctcgtgtcctcacctcggacaagaag tacagcacgagacgggaaggctgcgttgtggagctggtagttcacgatttagacttgaat gatgctggagaatatacctgtgtgtgtggagacaagacaaccacagctgttttgacagtg catgcactgcctccggaattcaaaaaagacctgaaggacctagaagctgtagaaagtggg acagctgctctgcactgcgagctgactaaacctgctgtggtgaagtggatgaaagggcag gaggtcctcaaagcaagcagcaaatataaaatgagtcaagatggtgctgttgcaaagctg attatccatgagctggatatggaggacactggagattacacctgtgtgtgtggagatcag cggacaactgccactttgacagtcaacgccctaccagcactttttaaacaagaacttcag aataccgaggcagaagaaggtggtacagcaacactgaggtgtgagcttaccaaacccaag gctccagtagagtggagaaaaggagatattactctctaccctggtttgaaatatgagatg aagcagcagggctccactgctgaattggtcatttatgacttagaactggacgattcagga aggtacacctgtgactctggacatcagcagacaacggctgtggtaaccgtacatgcactg cctgtcacgtttaagcaacccctacaaaataaggaatcagaggaaggaggtacagctaca ttctgctgtgagctgtcgaaacccaatgctgcagtggaatggaggaaaggaggagtgggg cttcagcccagccagaaatatgaaatgcggcagagggaatgcctggtagagctcttaatt cataatcttaaattagaagatacaggagaatacagctgtgatactggagatcaggaaaca aaagcatctttaaatgtgaaagctctgccagttcttttcaaaaaggagctcaaagacaag gaggcagaagaaggagctgcggtgaaattccagtgtgagctgacaaaggataatgcaacg gtggagtggaggaaaggcaccatgcagctcttcgcatgcgccaaatatgaaattaaacta agtggtcgcacagctgaacttgtgattcataatatagaaccagaagatgcctctgattac acgtgcgatacaggagaccagcagagcacagcagtcctcagagtgaatgccatcaaaccc cagctgaagcagcagctgaagaacgaagaagtggaagtgggaggaacggccaggctgcgc tgtgagatttccattagcaaagcagaagtggagtggaggaaagatggagtcgtccttcac tcaagttccaagtatgaaatgtggcaggacggcacgctccgcgagctgcgtgttcaccgc ctggagcctagagatgctggagagtattcctgcaaggctggggatgagacgagctctgca aaactgaccgtgaaagagcctgacgtgaccatcgtgagtggcctaaaggacatggtggtg tttgaaggggatgatgtcacgtttcggtgccaggtttctcatgaaaatgcaagggacgtt gaatggaagctacaggatgttgtgctgcaaaataatgaaatgaatgagatctcagtggaa aagggaaagattcacacactgacattaaggaaggtgactgagcaggacattggcaccatc actttccgagtggggcctcacacctcgacggcagagctcacggtaaaagaaccagcagca gccatagtggagacgctgaaggacgtcactttgtatgaaggagaagacgcggtgtttgaa tgcaggctgtcccgagaaaccactcaggatgcacagtggttcctgggggatgttcccctg caatccaatgaaatgaatgagatcagagtccaagggacacgtcacactttgatcctgagg aaggtgacactagaagactgtgggcctatcagtttcaaggtcgggcagcatacctcagca gcacagctaacggtccaagccaagaacagcattctccagggcttggagaacgtggaagcc gtggaaggaggggaagccctgtttgaatgctatctttccaaacctgaatgctacaactac aactggctgattgacgatgagcctgccaaaactacagaaaacactgagatggtttacttt gaaaatgggcgcaggcaccttctgctgctgaagaacctaactccccaggacagctgcagg gtgacttttacgtgcagcgatgcgatgacctcagccttcctgacggtgaaagggtggcgc ctacagatcttgcagcccctcacagatgttgaagtctctccaggagagaaagctacgttt agctgcgttctaagtgaagctgtgccaattaatgaagttgcctggtatagtaatgacata gagatccagtcagatgaggactgggaagtacaagcagatggaaacaaatacaaacttatt ctgaaaaaagcccaaccgcatcattctggagaggtgacctttgcttccagggaagcaatt gcatcagccaagttatctgtgatagcccaccccgatccacctgaagaaccagaagtttta agtaagaacagtcactctgtaactctgtcttggtacaagccattgagcgacggtggttgt gacatcctaggctacaacgtggagaggaaaatcccaggtattggctggcagtcctgcagc aaggccattattcaaaacacggagtttgtggtggacgatctcacgctgggtgaaccctac agattccgtgtctcggctataaacaaagttggggcgagtgagccggtgcacttccctcag acggtgcggctagagcctccagttacagtcacccatcctttggtgggaggatcagtctca gaaggggaggtggctcgcttggagtgccaattatcaagtgaaactgaaaagagagtgaca tggctcaaaggaaaagaacaaatacaagctggagggagatatgagatcctctctaatgga aaaaagcagatactcattatccatgcatttaaacctgaagatcaggacacatacacctgc atggtttctccagaagtcaaatctgttgccagcttgtgtcttgaagttcccacagtggca atgctaaaagagattgtccaggaagcatcctctgcaagccaaccagaagagctcgtggat ggccacgtccagcccagcttgccccctgaggctgctcaggagggagatcttcacctcctt tgggaagccctggccaagaaacgccggatgagccgggagcccaccttggattccatcagc gaggtgcctgaagaggatgagaagcttcagaagttgaggaaggaggaagcggagatgtct cactactactcagaggagtactccacatgtgatgagctggctaggacaggagaagcagat ttctctttcacaagctcagacgatgaatctagggctgggactccttcgctagtaaactac ctcaagaaagccgggaaggcaagcgtcagtgtgactagcaaggttcagtccattcccaca ggcaaattatggaaacagtgggagaaatccagcgtggagactgttgtggctgccccagct gctaaaccagctgaaccagaagtaccagatttagatgatccttccatgaacaaggccgct gtgaagatacaagctgctttcaaaggctacaaggtcaggaaagagatcaagcaacaagag tgcccagtgtttactgagaccttcaaagatttctctggtgagcctggaagcactctccac cttgagtgtgtggcccacagcaaaactgacatgaaagtccgttggctgaaagatggggaa gagctttcagacggtcgctactatcacatagacaattacagtgatgggacctgctctttg attatcactggcctggagaggaaagatgcaggtaaatacacctgtgaggcatccaataaa tttggcaaggtttcacacagtgctaaggtggttattggcagcactgacagtgagacagag agctcgtccggcagcgagctggatgatgctttccgtaaagcaggaaggagacttcacaga ctcttcaaggccaagatctcaacagagatatctgatgtggaggaagagctttttgtcagt gcagatgaaggggacatagaggtggttgaccatcagacatatcgtgaggatgaccagtac atctacatcaagtttgaaatcttgtccgaggcaaaaactgctgccactcgattcagagag atgtttggtgctctgggaattcccgtggagattgacattttggaacaaggccctaaaaaa attgaattgcgtattgggaaagcaacaccacccacccatgggaagtttgcaccaccagta gtgagacctccaccacctttgctgactactgatacagctcccatgttcatgactgagctc caaaaccaagaggtacaagatggctatccagtcagctttgactgcattgtcgttggcaaa ccactccccacggttcgctggttcaaggatggaaaagctattgaagaaaacgatcattac atgatcaatgaggaccaggaagggtgccatcagctgatcatcacagctgtggtccccact gacatgggcgtttaccgttgccttgctgaaaacaacatgggagttgcttcaaccaaggct gagcttcgagtggatttgaccagcactgactatgagacagcagcagatgcaacagagacg tcttcttactacagtgccaaagaatatatttcaagccgagaacaggaggaatctaccact gaggaggagcaattgccccagatcttcgatgagcttcatgatattcatgtggcacctgga gcatcactggctaaatttcacctgaaagtgaaagggtacccgcagcctcgcctctattgg ttcaaaaacggacagccattaaaagcctcggatcgtatcctcaagactgataaacaggaa ttccactcactggaaattcgggatgtcactaaggcagatgctggccagtactcaatattt gtcatcaattctgctggttctgcattttcgtcagccaggctgctagtcaaagatcctgat gagaaagaagagccatcagaaacagattcctttgagcagctgataccaccaagattccta gaaagatttactaataaaaaggtgaaaaaaggtgcaagcatcacattatctgtaaaagtt gaaggacatccacccccaactatcacttggctgaaagaagagtctcaggaagatatcctg tggatcaaaccagacactcctggatataaacttgccagttcaaatatgcatcacagtcta atcctgttggatgttaaaaagaagtacagtggaacttacacgtgcattgctaccaacaag gctggccagtccatctgcaccgccaccctggaagttgcagatgtgaaagaggctgaagtt ctgacccaggagcgtgtgatggtgtcagaagccatcatgaccacactgggagctattcat ccctctgaaacaggagaaggagatcttgaaactggtagagaaggtgtacccaaaagccct atttcattagctgatgttggctcagaagagtttttccagaaactcacctcgcatatctca gaaatggtatctgcaaaaataagtcaggctacacttcgagtgccaggtgcagaaagtgat gatgaatcaaaaactccctctgcatctcctcgccatggacgatccagaccttcatccatt gctcaggagtcctcctctgaatctgaagatggggattccagaggagagatctttgacgtc tacatggtcacagctgactacgtgcctgctgctcctgacagggagaccatcaccttgaag gaaggccaatatgtggaagtccttgattcagctcatcctctgaagtggctggtcaggact aaacccacaaaatctagcccctctcgacagggttgggtgtctccagcttatctggacaaa aaattaaagttgtcaccagagtggggaacaacagaagctcctgagttccctggagagttt gtttctgaagatgaatataaaaggaagctaagcgttcttattcaagagctgttgatctca gaagaggattacattcaagatctacagttcctccagactcatcatcttaagttcaccgag acctgtcccaatgtcccgggagctgtcgccagtcagaaatccaccatcttcagaaatatt gatgacattgctcgttttcattccagtgtcttcctccaaggcttgcagaaatgtgacact gatgatgatgtggccatgtgctttatcaagcacgaagcagagtttaataagtacatccag tacctcgtggggagggtacaggctgagtcgattgttgtcagcaaagccgtccaggatttc tacaagagatacacagatgaaattttaactaatgaagatccttcacagccacttatccca ccactgcagcactacctggaaaaacccataaacaggatccagcagtatcagactataatc aaggaattaatccgaaacaaagcaagaaatagccaaaactgcactttgctggagcaggct tatgccgttgtgtctgcactcacccgaagagcagaaaacaacctccacgtctcactcatt gagaattatccagggaccttggaaagccttggtgaacccatccgacagggccacttcatt gtgtgggaaggagctccaggagctagagtggcatggaaaggacacaaaagacatgtcttt ctcttcaaaaattatattgtgatctgcaaaccgaagcgagacacaaagacagacacctac agttacatctttaagaacatcatgaagctgaacaacatagacgtgaacgaccttgtggaa ggggatgaccgggcgtttgagatctggcacgaacgggaggacttggtccgcaagtacctc cttcaggcacgtacagtaaatatcaagaactcctgggtgaaggagatctgtggcatacag cagcggatcagcgagcccgtctggatacctccagactttgaggaagaactggcagagtgt acagctgagctgggagagacagtcaagctggcttgcaaagtcacaggagctcccaagcca tctgtcagctggtacaaagatggaaagcctgtggaggtggatccccatcacattataata gaagatcccgatggttcttgcacattgatcttggacaacctaacgggtgttgactcagga cagtacatgtgctttgcttccagtcctgctggaaacgccagtaccttaggaaagatcctt gttcaagtgccaccacggtttgtgaacaaggttagaaatgcttattttgtcgagggtgaa gatgctcagtttacctgtactattgaaggagcacctaggcctcaaatcagatggtacaaa gatggtgtactgttgaagaacacaagtaaataccagactttcagtgaaccacggagtggc ataatagtcctggtggtgaagaacccttccaatgaagatatgggacactatgaatgtgag ctggtgaacagattagggtctgcaaaaagtggagcagaactttaccatcacagtgctgca gccctgacccaggagaggagaggagaccaagccattaccatagaaggtcattcgccttcc cgctccccgagagcggagccaactccagagccagtttatgtttcaaagatcaggcagcct gtccacagacatgagcaggagacaacatcgaagtctgctgttcccatgctttttgtcaca gaaccagaggacaggcaaggagcagcagctagagatgtcatcacagagaccaagggggaa gagaaaaagcccaagtgggttgaagtggaagaaataattgaattcaaggtgaaaaaatca ccaaaacctgcaaggaaaagaggttcttccccagcaaaacaaggaaaagatgactcaggg gtgttaacgttcacttttcccagctcaaggcctaggcgttccccagaagatgatccgaac acaaacaactccaacaataaattggtggaacagtcaaaatctttgcctaatgacagtctc tctgaagccgatatccagcccctcgtgtatgcaaccgaggaagaaggacctcaagtcagc agcgaggacagaagctccccgtgtgagtccgaccagctaggaaatagttcctttatggat tatggaaccgaaggaaagagcttcccccaggaaacaagtgctcgctatgggtcggacgtt gcttccccgctgcttgcctgtgggggtgagcctctggtcttcagttttgagacggctgct gcagaccagcaggaacttctgttctcaccagcgagtccagaggttaaggaagaggtagat gaattagacatatcttggcctattgaagagggggtacccgaagtaatgcaagatgtcctt ccagaagaggataatgtcattatagttgatgaaccagaggaactacagacagacgacatt agcacccgggaccgcaaaatcttaacccacaatggcaaagtattaactctggaggatctt gaagactatgttcccaaagaaggtgagacctatgggtgtgacgaccagaaccgtagggca gagaaaccctgcgagatctctgtgctccagactgagattaacgagccaacgattgggaag ccagtgctgctgaatctggtgagacctgtggtgtccaagcccaggcaaagatttttcagc cagtttgaggagcacattcccgggggcatgttcatgacagcatctagagtaaccggcgtg cagtctgtaggcccctcaaacatctctttccacgtgacgcctggagtgcacgcagcaaca gcagcagcttctcccggtccctccttcacagtgaaaccatctttctgcaccgaagtccag ctctcagcagacaatggacagtcaagctttaaaactgaagtttccacaagaaccctcagc tatggaactgttggaatgacttccccacagtcagaggtggagacttctgtccaggcctcg cttcagcgtgccgataaggagatcaagacagctctaaagaaactcgtggactcggcatca ctgctggtgactcttcccccgggcatgcgagaagaagtcggtggccttggccttcctggg tccattccttcagaccactcagaaacagcagccgggccctctgtgctagttcatgaagcc agtacccaaacccagactgctggagggcatgacaaagcacaaaggcaggtcccagccgaa gaaccaagcgtgccaaagcccagccctggtccttcctctgaagagacagctgctggagat gagagcactcaggagcgcactgttcctattaccagaacatcaccagccacaggggcagga ggctggtacagaagagaaggagatgtggtctgggatgtacacagtgaagtttatattgag accacggaaagaacttgtgtgtataagactgaggagaagaccccaacaagtcctccctat atgcaagtgacaatcgaggatgtgcaggtgaattctggggagcgtgccaaatttcaggca gtcattgaaggaacccctcagccaaccgttttgtggtttaagggcacttccttgctgaca gacagcaacaggctccatcaagggaaggaaggaacaacatatttcttagtcgttgacaat gctgtctcagaagatggtggtgtttatacctgtgttgccaaaaatgcaggaggggaggtt ttgtgcaaagcagagctgattgtacatgaaggtaataaagaccaagcggcaaagaaagtg gccaccaggagaaagctccattccctttatgaggttaagcaggagattggaaggggctgc ttcagctttgtgaaacgagttgtacacaaagggaacagagtgtcttgtgctgccaaattc atacctctacgaagcaaaacgaaggctcgagcgcatcaagagagggatattcttgcctct ctatcccatgacagaattaccaggctcctggatcagtttgaaacacggaaaacactgatt ttgattctggagttatgctccagcgaagagctccttgaccgtttattcaagaagagtgtt gtcactgaagcagaggtcaaattgtatatcaagcaaattttggaaggaatcaaatatctt catgataacaacatccttcatttggacattaagccactgaatatcctcatggtttatcct gaaagggaagaccttaagctctgtgactttggatttgctcagaagatcacgccctctgag cctcagttcagcaaatacgggtctccggagtttgttgccccagaaattgtttctcagtca ccagtgtcaaaaggaactgatatctgggctgttggagtcatcacatatttaagcctaaca tgcaagtctccatttgctggggagaacgacagaggaacccttataaatatccagaatggg gaaatttcatggaccactcctgattttgttcacttgagtgaagatgcaaaggactttatg aaagggattctacagcaggaccccaaagccaggcctagtgcttcggactgtctttcccac cagtggttcatgcataatccccccctcgaagcagctcatttcattaataccaagcagctc aaattcatcgtggctcggagcaagtggcagcggtctctgatgtgctataaatccatactg gtaatgcgatctatcccagaaatcctagaaaggactcatgacaacacctccctggccatc tcccgacatcttattgacgaaagcacttcatccagtaccagcggctcctcttcagacaat gagaactcgcacttccccacgaagaggcactttggctctacacccgaactgcacttgtcc atatttgatgcaccaagccaccaggagcctccaaaacatgcaagagaagagaagcaaacc aaaatctctgtccctccagtaaaacccatgaggaggaagtatgcttcaatgaaaggtgag gtgggggacaaatcacctacagaaagtaaagagctcatggcaagtatcttaaaggagaaa gaagaagggctccttcccagacttcaagatgaaggagcagagcagtcccaaagaagtggt gctgctgagccttcatcagtgaggacttccacggaaagcacatccaatctatgtcagaag gaaaaaccagatgtatttttatctgataaggacagaattgaaaaggctggggatgggaca gaaaagccacctgtctgtgtccctagacagagtgtcattaaaagcactttctacagccaa gcagctgagctacctgccagggggccttcctcaccaggcagggagttcagaaggcacctg gacagagccagaagaactttccggaaagctggatattcaaaggtgcccctcagtggtctc cgtgaacccctcctagagcagtttgaactggaagaagaagaaggaaagtctgactatgga gatgatcacagggaaagtctgcttggttccttgaccaaatcagcttcatttgacactgca aggaaaccaccacatcctgccatcgctggtgggagccgaagccgttccctggatgactac aggctgagagcgtcaagatcagtgagggaacagcatattttggaagaagactgtgatata ttgtcacaggaaagttgcgctgaaggtggcgaccactgcgacatttctgcagggcctggc aagggatgttttgtagacactgcaaagcaagaggactttaggagaaccagcaaggattgc tcagaagagcagccccctccttccacgcaatgtgagggtaatgggtgcccagctggtttt gtgcaacagctagagagacttccagtgtcgcctcataggagcgagaataggaaacattta ctgaagaagtcaaaagctacttacattgaggaggaagtcaaagatttggaaggcaaaagc cccattctgactgcccagggctcagatgtaactgcatcatcagctcaaaaacatgaaagc atggagggtaaatctttccctggcagtgcctctgacactgcttttcaggagggaaaacag tccatttcaactctcacaaagccagagaccacctccaagacggcccctacgagtaaggga gatgcgtatctgccccaggagtctgctcacagtaccgacgtccatccagacctaaaaggt gggagcttgcttatccaaaggacagccccagttccaccttggaaagacaaaaggcagaaa cattcgcatgagaagacttctgctcatagcgttgtcaaatctgatctcacggagcatgaa agctctgctgttttaacaggcccacaaacagaaacagattcccttccagtatgtaaagac aaaagtcaggaactttctggtcaaactgttccagcaactactgccttggtgggcatacgg ccagataccctaactgctctgcacacagctgatgaaggggctcatcagaagatgaaaacc cataaagagatgaagtcagctgtcctggaggatgaaggaccaggtattacaggaatcact ccaccatcagcccatgatggtgaaagccaagcgtgcaagagggctgctggtcacgtagac acagaatcagccgtcctgaagggagagcatctcattccaaaagtcccaccaccaaaatca acgccgaccttggtctccgatggagcagagaaggcggaaagggaatggccagctcgtagc aaggacaggcttgctgttttgaggaatgaaagctcagctgtcacagaggttgttcccagt ttggcccatgaggctgaaatcgagggcactgaaccccagaaagtttctgaaggccgtggc acggtgcctgctgttcgggagagcagacaccgagctagaactgtgtcctcccaaaatact ggcctcccttcggcctgtgagaaggaaaagcaagaacgttcaaaggcaccgcttcgcagt gaggtcagatctgttgtgacagcaagtgcaagccgagcagctggacagactatgcctgct cccgtccccaaggctggacctcaggtgtttgagcagcacagggttgtacatcccggtggc agagtttctactgatctgaagagcgggcctccgggtgtcttaactgcttcaccaccagaa gctgctccagcttcagtttatgagctagaatatgaggaatatccaaaggtttatggtgag ggtagaagtgttgccttagaaagtggaagctgggatgctggaaaaactgtcccaccatca ctcggcaaggatcaaagtcaggagctctcacatcacaggtcttctttttacagcgatgag gagtctgccgtgctggagggcttagtggatgagatggtttccctctctgaagagatgaat gtttgggcagagtcagtctctggtgaggaggaatgcagaaagcccatctctgctcccaca gagatgttctacaaaggcttaggtacccaagcgcccatggacacctccttcccttcggta caagggggtaaaagagaggtctctgagctggatgaccttgcagaaccctatcttgttgtg agtgaggagtcagtggtactggaagggcagggagtacagacggttcctcatgaatgtgag catctggaggacttagcgtttgagagccccacttctagtcaagtgagtgtttcctcaaca gaaagcctggacactggaaaaagacccagtcaagtgacggtgagcaaggacactggtaaa cacccagaagtttctttagtgaaaatcaaagacctgtcggacgaaacgcccagtcttggc agtggaactccaaaacttgacatatcagaggtagagcctgcctatttgaatttctctgac ttgtatgacattgtctattttccatttgaatttatgaactataggaagcctccacccaaa ccaactggtagacggtttataccttttggtgaaagggcaaggtcacctcctgcaagacat ttgcataaggataaaagactgtgcatcagagaagaggcagaggacaagaacaggaagaac catttggaaatatctgaggattcaaaggcaactaacttactagccatggggaaagggtca gagagtcataaagaaatgtatggcccccaaaagggctcaagtggtaagcagaaaagctcc ttctacaacaagccggggctctttaagccatatgcaaggtctcattcagtggagcagtca gtggagcagagtctgaagaagaaagtaaaagcttctgttgcccatatttcaaaaatcctg aaaggaaagatatctcctgagccagaggcagaagaaggatctctgaagaggaaatcagca ctctcttcattcaagttctcaagcctcatgccaaaggagaaagcaccttcgttcactgag gagctcatcgatcaggctgctgccatcggacagtgcgtgacgctgtcgtgccggacggcc gctcactcctccctgcacatcaactggttccgagatgggatagctgtccacagcagcagc cggatccttatctcagccacgctcaaaaacttccagctattaactattctctctgttaat gctgatgattttggtatttacacctgcgtggccacaaactccctgggctcagcatccacc tcttgcgtcataagaaaagcagagcttcctcccagccctccaccccctgacatcgtggag gtctacgaggatggagtgcaggtggtctggaaacctgtggaaaccaacacccccgtccat tacactgtccagtgcaagagcgaagatggggagtggacgactcttgcttctgacatcgct gactgctgctactatgccaaaaatctctccaaggggtttatctactgcttcaggatagcc tgcaccagtaaagcaggaatgggcccttacagcgacccatctgccaaagtaaaaatcact ggcaaggatcaaatggctgctactgaagaagagagcgaaataatcacaccatccgagcct ttcccaacctaccagacctacgccttccaaacagagatcaaaaggggtcgtttcagcatc gtccgacagtgcagggaaaaagtaagcggcaagactttagctgctaaaattatcccttac tggcaagaggacaagcaaactgtgctcctggagtaccaagtcctgaggaagcttcatcac acaaacatagctcagctgaagggagcctacgtcagcccacggcacttagtgctgatccag gagatgtgcgtgggaccagagctactccactctttggcattacggacatcatactccgaa gtggaggttcgagactacttgtggcagatcctcagtgccacggagtacctccacgcacac aacatcctgcacttggatctcaggtctgaaaacatgatcatcactgagcccaacctgctg aaactcctggattttggcaatgcacagttctacacacaagacaaagttattaccatggac aagtgcatggactatgttgaaaccatggaactgctgacagagcaaggagccctcccgcaa actgatatctggtccgtcggaatcacggctttcatcatgttgagtgccaactaccccatc agctccgacgtagcctgcgagtttctgagaacaaccaggaggggtaaagtgaagctcaca cggtgctacgcgggtctctccgggggagcggtgtcctttctccagagtacgctgtgtgca aacccctgggatcctcctcaccagcacggatccccgactgatcttctcacctttgtctgt tctaggggaaggccgtcagcctcggagtgccttcagagcccgtggctccaggagacaggt ttagacaacaggcagcaagccctggttaccttccccaccaccaaactgaggaatttcctc accgaacgggaaaagaaaaggggcctgctgtgctccaagtacggcctcatgattgcacag tga

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