Haliaeetus leucocephalus (bald eagle): 104832595
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Entry
104832595 CDS
T08630
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
hle
Haliaeetus leucocephalus (bald eagle)
Pathway
hle04217
Necroptosis
hle04620
Toll-like receptor signaling pathway
hle04621
NOD-like receptor signaling pathway
hle05164
Influenza A
hle05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
hle00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
104832595 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
104832595 (TYK2)
04621 NOD-like receptor signaling pathway
104832595 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05164 Influenza A
104832595 (TYK2)
05168 Herpes simplex virus 1 infection
104832595 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hle01001
]
104832595 (TYK2)
Enzymes [BR:
hle01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
104832595 (TYK2)
Protein kinases [BR:
hle01001
]
Non-receptor tyrosine kinases
JAK family [OT]
104832595 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
SH2_1
FERM_F1
Kinase-like
Kdo
SH2
ABC1
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
104832595
NCBI-ProteinID:
XP_010567152
LinkDB
All DBs
Position
Unknown
AA seq
1186 aa
AA seq
DB search
MSLCQCTVKHSESDAEGCCFLASSGLKVCLHWSGEEEQERCQTYAQGTLSAEEICIDLAR
RIGITPLCYSLFALYDTQSRVWLPPNHLFKISKDTNLNLLFRMRYYFRNWHGMNDKEPAV
YRNVPRQSDSPDEKLQGGALLDKSSFEYLFEQGKFEFINDVASLKDLQTEQEIQRFKNES
LGMAVLHLSHIAIKKGISLEEVARKYSFKDCIPRSFYRQIQQNNYLTKFRMKNVFKKFVQ
RFQRHTVSTGKLTVQDIMYKYLATLEHLAPRFGSELFPVLSLETSSEGEKVQLYVNGGHS
QLEHGQALLPKDRPVTHEVLVTGTTGIQWRPVPVESIENFSHRGYFGRKSRNKELEPKGP
TQPAERSEPKWVHFCDFREITHIVVKDCRVSINRQDNKCLEVVLPSPESALSLVSLVDGY
FRLTADSSHYLCHEVAPPRLVMSILNGIHGPMQEEFVFAKLRREEQEEGLYIIRWSVLDF
NRMILSVVKRGHQQAPGVQGALKYRQFRIQKKGNSFVLEGWDREFSTLRELLDVLKGCTL
KSGDESFTVKRCCPPKPGEISDLLIMRKVKDSTKQILNLTQLSFHQIRKNEITQRAHLGQ
GTRTNIYDGVLNVCGTTGADDEAEYFSTEQNNNSREMHVVLKVLDPSHRDIALAFFETAS
LMSQVSHVHLAFVHGVCVRGSENIMVEEFVEHGPLDVLLRKEKGRVTVGWKITVAKQLAS
ALSYLEDKNLVHGNVCAKNILLARKGLEDGSVPFVKLSDPGVSFTVLSREERVDRIPWIA
PECVWDVGNLSTAADKWSFGTTLLEICFDADVPLKERTPSEKERFYEKRHRLPEPSCKEL
ATLICQCLNYTPVERPSFRTILRDLTQLQPHNLVDVTSVNPDFPVSDPTVFQKRYLKKIR
ELGEGHFGKVSLYCYDPTNDGTGEMVAVKSLKSGCSQQLLTSWKREIEILKTLYHENIVK
YKGCCSEQGEKIVQLIMEYVPLGSLRDYLPKHNVSLAHILLFAQQICEGMAYLHSLHYIH
RDLAARNVLLENENVVKIGDFGLAKAIPEGHEYYRVCEDGDSPVFWYAVECLKECKFYYA
SDVWSFGVTLYELLTRCDSSQSPPVKFIEMIGATQGQMTVLRLIELLDRGKRLPSPKDCP
CEIYRLMKNCWEAEASFRPAFHNLVPILKNFHEKYRAQAPSVFSLC
NT seq
3561 nt
NT seq
+upstream
nt +downstream
nt
atgtctctgtgccaatgcacggtgaagcacagcgagtcggatgccgaaggctgttgcttc
ttggcgagcagtggcttgaaggtttgcctgcactggagtggcgaagaggagcaggagcgg
tgccagacctacgcccagggcacactcagcgccgaggagatctgcatcgacctcgcacga
aggatcggcatcacgccgctgtgctacagcctcttcgccctctatgacacccagagccga
gtctggctcccgcccaaccacctcttcaaaatcagcaaagacaccaacctcaacctgctt
ttccgcatgaggtactactttcggaattggcatgggatgaacgacaaggaaccagcggtt
tatcgcaatgtgccccgacagagcgattcccccgatgagaagctgcaaggaggagccttg
ctcgacaaatcgtccttcgagtatctgtttgagcaggggaaatttgaattcatcaatgac
gtcgcgtctttgaaagacctccagactgaacaggagatccagaggttcaagaacgaaagc
ttgggcatggccgtgcttcacctctcgcacatcgccatcaaaaaaggcatctcccttgag
gaagtggccagaaaatacagcttcaaggactgcatcccacgttccttctaccgccagatc
cagcagaacaactacctgaccaaattccgcatgaaaaacgtcttcaagaagtttgtgcag
cgtttccagcggcacacggtcagcaccggcaagctgacagtgcaggacatcatgtacaaa
tacctggctaccttggagcacctcgcacctcgctttgggagtgagctcttccctgtgctc
tccttggagacctcctccgagggtgaaaaggtgcagctgtacgttaacgggggacattca
cagctggagcacgggcaggcgctgctccccaaggaccgacctgtcacccacgaagtcctt
gtcaccggcacaaccgggatccagtggcggcccgtacctgtagagagcatcgagaacttc
tcccatcgtgggtattttgggaggaagagcagaaacaaagagctggagcccaaggggccg
actcagccagcagagcggagcgagccaaaatgggtccatttctgtgatttccgggagatc
acacacattgtcgtcaaggactgtagggtcagcatcaaccggcaggacaacaagtgcctg
gaagtggttctcccatcccctgagagcgcgctttccttggtttcactggtggatggttat
ttccgactcacggctgactccagccactacctgtgtcacgaagtggcaccgccgcgactc
gtgatgagcatcttgaatggcatccatgggcccatgcaggaggagtttgtttttgccaag
ctacgacgggaggagcaggaagaagggctctacatcatccgctggagtgtccttgacttc
aacaggatgattctctccgtggtgaaaaggggccaccagcaggctcctggggtgcaggga
gccctcaagtacaggcaattccggatccaaaaaaaaggaaactcctttgtgctggaaggg
tgggaccgggagttttccactttgcgggagctcttggatgtactcaagggctgcacgctc
aaatctggcgatgaaagcttcacggtgaagagatgctgtccacccaaaccaggagagatt
tcggacctgctgatcatgcggaaggtgaaggatagcacgaagcagatccttaacctgacc
cagctcagcttccaccagatccgcaagaacgagatcactcagcgagcccacctggggcag
ggcacccgcacaaacatctacgatggggtgctcaacgtctgcgggaccaccggggctgac
gacgaagctgagtatttctccaccgagcagaataacaacagccgggagatgcacgtggtc
ctcaaagtcctggatcccagccacagagacattgccctggcgttttttgagacagccagc
ctgatgagccaagtgtcgcacgtccacttggctttcgtgcacggagtctgcgtgcgaggt
tccgagaatatcatggtggaggagtttgtggaacatggacctctggatgtgctgctgcgg
aaagagaaaggccgggtcaccgtgggctggaaaatcaccgtggccaagcagttggctagt
gccttgagctacctggaggacaaaaacctggtgcatggcaacgtgtgtgcaaaaaacatc
ctgctagccaggaaggggctggaagatggatccgtgcctttcgtgaagctcagcgacccc
ggagtcagcttcacggtgctctctcgagaagagcgcgtggaccggatcccctggatcgcc
ccggaatgcgtctgggatgtgggaaacctcagcactgcagctgacaaatggagctttggc
accacgttgctggaaatctgcttcgacgccgatgtcccactcaaggagcgcactccttcg
gagaaagaacgtttctatgagaagagacatcgcctgcccgagccgtcctgcaaggagctg
gccaccctcatctgtcagtgcctgaactacacccccgtcgagcggccgtccttccggacc
atcctgcgggatctcacccagctccagccgcacaacctggtagacgtcacctcggtgaac
cccgacttcccggtgtcggaccccaccgtctttcagaagcgttacctgaaaaagattcgg
gagctgggggagggtcactttggcaaggtgagcctgtattgctatgaccccacgaacgac
gggacgggggaaatggtggccgtcaaatcactcaaatctggctgcagccagcagctgctg
accagttggaagagggaaatcgagatcctcaagacgctttatcatgaaaacattgtcaag
tacaagggttgctgcagtgagcagggagagaagatcgtgcagctgatcatggagtacgtg
cccctcggcagcctgcgcgactacttgcccaagcacaacgtcagcctggcccacatcctg
ctcttcgcccagcagatctgtgagggcatggcctatctgcactccctccactacatccac
agggaccttgctgctcgcaacgtgctgctggagaatgaaaatgtggtgaaaatcggggat
tttggtttagccaaagccatccccgagggccatgagtattaccgtgtctgcgaggatggg
gacagccccgtcttttggtacgccgtggagtgcctcaaggagtgtaagttttactacgcg
tccgacgtctggtccttcggggtgactctctatgagctcctgacccgctgcgactccagc
cagagccctcccgtgaaattcatcgagatgatcggggcgacgcaggggcagatgacagtg
ctgcggctgattgagctgctggacagggggaagaggctgccaagtcccaaggactgtcct
tgcgagatttaccggctgatgaagaactgctgggaagcagaggcttccttccgcccagcc
ttccacaacctcgtccccatcctcaagaacttccacgagaaataccgggctcaggctccc
tccgtcttcagcctctgctga
DBGET
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